Vascular Anatomy and Computational Hemodynamics: Fluid-Structure Interaction in Cardiovascular Devices and Disease
Cardiovascular biomechanics is advancing rapidly through the integration of patient-specific anatomy, advanced imaging, experimental techniques, and computational modelling. A central research direction is the investigation of hemolysis, shear stress, and thrombosis risk associated with implanted cardiovascular devices, including stents, heart valves, and angioplasty devices. Imaging-driven characterization of vascular structures, using techniques such as microtomography and digital image correlation, can be integrated with fluid-structure interaction (FSI) models to capture the dynamic interplay between blood flow and deformable biological tissues.This Research Topic aims to advance understanding of the interactions between biological tissues, blood flow, and mechanical forces under physiological and pathological conditions, with a particular focus on patient-specific computational fluid dynamics (CFD) modelling of blood flow in arteries, veins, and the microcirculation. Coupling CFD with FSI enables realistic modelling of blood flow interacting with deformable vascular tissue, while advanced imaging and experimental techniques provide data on vascular structure and tissue mechanics for integration into these models. Submissions should keep biomechanical or computational analysis as the primary focus, rather than clinical outcome studies in which biomechanics is a secondary consideration.The main aims of this Research Topic are to:• Investigate the biomechanics of arteries, veins, the heart, and microcirculation using experimental and computational approaches.• Develop patient-specific CFD and FSI models to characterize blood flow and hemodynamics in healthy and pathological states.• Determine how vascular anatomy, geometric variation, and tissue mechanical properties influence blood flow and cardiovascular function.• Apply advanced imaging techniques, including microtomography and digital image correlation, to characterize vascular structure and tissue mechanics for integration into computational models.• Assess shear stress, hemolysis, and thrombosis risk associated with cardiovascular disease and implanted devices such as stents, heart valves, and angioplasty devices.• Apply biomechanical knowledge to the design and optimization of biomaterials, stents, heart valves, prostheses, and other cardiovascular implants.We welcome original research, reviews, and methods articles using experimental, computational, or hybrid approaches to address these aims. Topic editors: Łukasz Makowski, Bogdan Ciszek Source: https://www.frontiersin.org/research-topics/86932/vascular-anatomy-and-computational-hemodynamics-fluid-structure-interaction-in-cardiovascular-devices-and-disease
Articles in this collection
No articles published in this topic yet.
