Volume II: Revolutionizing Cardiovascular Diagnosis: Innovation and Clinical Translation of Functional Cardiovascular Imaging

Functional cardiovascular imaging has advanced faster than the evidence needed to act on it. Volume I of this Research Topic (63789) showed how quickly the field is moving, with 4D flow MRI, FFR-CT and advanced stress echocardiography reshaping how we assess cardiac anatomy, physiology and function. Volume II builds on that foundation and turns to the next question: how these technologies move from technical innovation to reliable, everyday clinical decision-making.We are particularly interested in work that is clinically consequential — studies that test whether new imaging methods change diagnosis, management or outcome, rather than describing capability alone.We welcome submissions on, but not limited to:• Next-generation modalities: photon-counting CT, hybrid PET/MR, ultrafast and contrast-enhanced ultrasound, and other emerging platforms.• AI beyond image interpretation: accelerated acquisition and reconstruction, automated quantification, foundation models, and the validation and generalisability these methods require.• Molecular and metabolic imaging: targeted tracers and probes linking imaging signal to underlying disease biology.• Imaging biomarkers and risk prediction: quantitative markers with demonstrated prognostic value, including radiomics and computational modelling or digital twins.• Multimodal and multi-omic integration: combining imaging with clinical, genetic and molecular data.• Disease-focused applications: heart failure, cardio-oncology, inflammatory and infiltrative cardiomyopathies, congenital disease, and structural intervention planning and follow-up.• Therapeutic monitoring: imaging endpoints used to track response to drugs, devices and procedures.• Reproducibility, standardisation and access: multicentre validation, harmonisation, cost-effectiveness, and point-of-care or resource-limited settings.As before, submissions should demonstrate clinical consequence, not capability alone. Topic editors: Heng Ma, Kai Lin, Wen Qin Source: https://www.frontiersin.org/research-topics/85224/volume-ii-revolutionizing-cardiovascular-diagnosis-innovation-and-clinical-translation-of-functional-cardiovascular-imaging