Articles

Showing 45 articles

• Review

  Published 8 October 2026

  Investigating protein conformational ensembles by native mass spectrometry and complementary biophysical techniques—the case of α-synuclein

  Stefania Brocca · Erika Ponzini · Carlo Santambrogio · Rita Grandori

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1887194

• Hypothesis and Theory

  Published 2 October 2026

  Piezometric architecture and the geometry of plasticity: a proposed electromechanical model of the Fibrosis–Plasticity axis

  Alejandro Carballo

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1806846

• Mini Review

  Published 29 September 2026

  Electrochemical scanning tunneling microscopy as a tool for probing protein function: from electron transfer to molecular recognition and chemosensation

  Josep Samitier · Anna Lagunas

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1945182

• Perspective

  Published 23 September 2026

  Peering beyond the fourth wall: should protein quaternary structure be a state space?

  Daniela Diana · Yimon Aye · Marcus J. C. Long

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1923311

• Perspective

  Published 21 September 2026

  Trans-spatial phase coupling at the lipid boundary: harnessing membrane biophysics for therapeutic condensate regulation

  Doris Loh · Russel J. Reiter

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1950241

• Perspective

  Published 16 September 2026

  Beyond static geometry: dynamic curvature in mechanobiology

  Zoé Barbier · Rémi Tranzer · Marine Luciano

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1920384

• Mini Review

  Published 3 September 2026

  Recent advances in mass spectrometry methods for the investigation of oligomeric intermediates of amyloid protein aggregation

  Carlo Santambrogio · Erika Ponzini · Frank Sobott · Rita Grandori

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1939530

• Mini Review

  Published 3 September 2026

  Beyond RNA/DNA: exploring the emerging role of Poly(ADP-ribose): structure, function, and condensate formation

  Lipika Baidya · Hung T. Nguyen

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1930609

• Original Research

  Published 31 August 2026

  Benchmarking protein-ligand co-folding across Nav, Cav and Kv-family channels

  Yu Zhu · Taufiq Rahman

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1937302

• Perspective

  Published 26 August 2026

  Biomolecular condensates, emergent properties, and the mesoscale concept gap

  Jeremy D. Schmit

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1927727

• Perspective

  Published 20 August 2026

  IDRs lead the way: cooperativity between intrinsically disordered regions and structured interaction domains drives enrichment in transcription condensates

  Arad Abazari · Dinitha Y. Caldera · Alisha Budhathoki · Ganesh Pandey · Mehdi Shafiei Aporvari · Filmon A. Medhanie · Jan-Hendrik Spille

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1891221

• Original Research

  Published 13 August 2026

  Revealing intermediate states of voltage-gated potassium channels with physics-informed deep learning: application to Kv7.1

  Julia Kacher · Mounir Tarek

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1877588

• Review

  Published 12 August 2026

  Silent Kv subunits as major players in cell membrane excitability

  Mohammed Alshemery · Mert Beyazyildirim · Joao L. Carvalho-de-Souza

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1925801

• Original Research

  Published 6 August 2026

  Targeting cancer matrix mechanics: fibronectin fiber relaxation correlates with ADAM8 expression in PDAC and is amenable to in vitro modulation

  Konstantin M. P. Wolf · Lea S. Ottenwald · Martin Wartenberg · Mamta Chabria · Viola Vogel

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1781425

• Mini Review

  Published 6 August 2026

  Probing peptide-mediated membrane pore formation by fluorescence, infrared spectroscopy, and atomic force microscopy

  Suren A. Tatulian · Munira Haque

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1870174

• Editorial

  Published 24 July 2026

  Editorial: Structural and functional roles of membrane transport proteins in cellular physiology

  Olga Vinogradova

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1926644

• Original Research

  Published 14 July 2026

  From scattering curves to structural descriptors: interpretable machine learning maps SAXS/WAXS signals to RNA structural details in defined RNA motifs

  Weiwei He · Serdal Kirmizialtin

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1769000

• Mini Review

  Published 10 July 2026

  Intrinsically disordered regions as drivers of protein aggregation: mechanisms, phase separation, and emerging predictive frameworks

  Rahul Kaushik · Suyong Re

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1880887

• Original Research

  Published 8 July 2026

  Chromatic discrimination in protocells toward proto vision and intelligence

  Panagiotis Mougkogiannis · Andrew Adamatzky

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1839006

• Hypothesis and Theory

  Published 8 June 2026

  Threshold transitions of 15 N fluxes reveal state-dependent root conductance and flux partitioning within steady-state nitrate isotherms

  Erwan Le Deunff · Philippe Malagoli

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1677942

• Mini Review

  Published 1 June 2026

  Biomolecular condensation meets membrane biophysics: from interfacial physical principles to emerging therapeutic opportunities

  Agustín Mangiarotti · Ernesto E. Ambroggio · M. Soledad Celej

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1860065

• Original Research

  Published 4 May 2026

  Linker peptide acts as an external mechanical clamp in a designed polyprotein

  Yanwei Wang · Bin Zheng · Peng Zheng

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1808825

• Review

  Published 1 April 2026

  Novel therapeutic approaches targeting biomechanical pathway alterations in bone diseases

  Malkiet Kaur · Manju Nagpal

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1773451

• Mini Review

  Published 25 March 2026

  From the classical colloidal theory to biomolecular condensation: implications in health and disease

  Noelia A. Melian · Aldana Gomez · Milagros B. Abate · Pamela L. Toledo · Mario R. Ermácora · Diego S. Vazquez

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1795884

• Review

  Published 9 March 2026

  IDRs in Cross-Membrane Transport: Regulation of Ion Channels and Transporters, Mechanistic Studies Made Possible by NMR and Computational Methods

  Olga Vinogradova

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1804302

• Original Research

  Published 8 January 2026

  Functional study of a novel SCN4A variant c.611C>T identified in a Japanese patient with myasthenia

  Natsuki Kira · Kosuke Yoshida · Satoe Takahashi · Ayami Yamanaka · Takashi Kimura · Kazuaki Homma · Masanori P. Takahashi · Tomoya Kubota

  Frontiers in Biophysics

  doi 10.3389/frbis.2025.1710099

• Review

  Published 3 December 2025

  A blurry view of fuzzy objects: on the roles of low-resolution structural techniques in discovery and early characterization of intrinsically disordered proteins

  Vladimir N. Uversky

  Frontiers in Biophysics

  doi 10.3389/frbis.2025.1693360

• Biophysics

  Published 30 October 2025

  Vesicular and plasma membrane glutamate transporters

  Bart Borghans · Natalia Dmitrieva · Aleksandr Nikiforov · Christoph Fahlke

  Frontiers in Biophysics

  doi 10.3389/frbis.2025.1693508

• Biophysics

  Published 8 October 2025

  Proton channel Hv1 modulates microglial responses to neurological disorders

  Maite Stratmann · Caterina Gagliardi · Melania Capasso

  Frontiers in Biophysics

  doi 10.3389/frbis.2025.1681011

• Biophysics

  Published 2 October 2025

  Identification of voltage-gated calcium currents in Helix (Cornu) serotonergic neurons, subcellular localization, and role in calcium dynamics and cellular firing of Ca V 2.1 and Ca V 2.2 subtypes

  María Laura Ríos-Reyes · Silvia Calvo-Corea · Oscar Brenes

  Frontiers in Biophysics

  doi 10.3389/frbis.2025.1652466

• Biophysics

  Published 18 September 2025

  From biophysics to cellular function: neural TELCs-membrane-anions capacitor transmembrane potential

  James Weifu Lee

  Frontiers in Biophysics

  doi 10.3389/frbis.2025.1648934

• Biophysics

  Published 7 August 2025

  Nanotribology of viruses reveals their adhesion strength and modality of motion on surfaces

  Charles Ault · Claudia Simon · Irina B. Tsvetkova · Pedro J. De Pablo · Bogdan Dragnea

  Frontiers in Biophysics

  doi 10.3389/frbis.2025.1623880

• Biophysics

  Published 23 May 2025

  Interaction studies between calmodulin and gating brake peptides from T-type channels

  Shivani Yaduvanshi · Veerendra Kumar

  Frontiers in Biophysics

  doi 10.3389/frbis.2025.1569091

• Biophysics

  Published 25 April 2025

  Activation of transient receptor vanilloid 4 increases connexin hemichannel activity in porcine ciliary nonpigmented epithelium

  J. F. Ek-Vitorin · M. Shahidullah · N. A. Delamere

  Frontiers in Biophysics

  doi 10.3389/frbis.2025.1543172

• Biophysics

  Published 4 April 2025

  Decoding TBCK: from bioinformatic insights of domain architecture to disease implications

  Emma M. Cagwin · Caitlin M. Padgett · Yvonne Lin · Wen Zhu

  Frontiers in Biophysics

  doi 10.3389/frbis.2025.1560824

• Biophysics

  Published 6 November 2024

  Functional dynamics of human ubiquitin C-terminal hydrolases

  Sarita Puri · Shang-Te Danny Hsu

  Frontiers in Biophysics

  doi 10.3389/frbis.2024.1479898

• Biophysics

  Published 12 June 2024

  Unlocking the brain’s zinc code: implications for cognitive function and disease

  Soheila Sabouri · Marzieh Rostamirad · Robert E. Dempski

  Frontiers in Biophysics

  doi 10.3389/frbis.2024.1406868

• Biophysics

  Published 7 May 2024

  Chaperone regulation of biomolecular condensates

  Jared A. M. Bard · D. Allan Drummond

  Frontiers in Biophysics

  doi 10.3389/frbis.2024.1342506

• Biophysics

  Published 8 March 2024

  Utilizing surface plasmon resonance as a novel method for monitoring in-vitro P-glycoprotein efflux

  Phuong H. Nguyen · Shuolin Cui · Amanda M. Kozarich · Alex Rautio · Arthur G. Roberts · May P. Xiong

  Frontiers in Biophysics

  doi 10.3389/frbis.2024.1367511

• Biophysics

  Published 23 February 2024

  Symmetry of a partially-ligated state maintained by dynamics in a negatively cooperative system

  Rebecca Strawn · Parvathi S. Murthy · Rüdiger H. Ettrich · István Pelczer · Jannette Carey

  Frontiers in Biophysics

  doi 10.3389/frbis.2024.1359979

• Biophysics

  Published 8 January 2024

  Expression, purification and folding of native like mitochondrial carrier proteins in lipid membranes

  Marzieh Tabefam · Matthew D. Smith · Masoud Jelokhani-Niaraki

  Frontiers in Biophysics

  doi 10.3389/frbis.2023.1334804

• Biophysics

  Published 4 January 2024

  Archaea membranes in response to extreme acidic environments

  Parkson Lee-Gau Chong

  Frontiers in Biophysics

  doi 10.3389/frbis.2023.1338019

• Biophysics

  Published 17 July 2023

  Protein structure and dynamics in the era of integrative structural biology

  Rita Grandori

  Frontiers in Biophysics

  doi 10.3389/frbis.2023.1219843

• Biophysics

  Published 14 June 2023

  Grand challenges in biomolecular condensates: structure, function, and formation

  Danny M. Hatters

  Frontiers in Biophysics

  doi 10.3389/frbis.2023.1208763

• Biophysics

  Published 26 May 2023

  Grand challenges in biophysics

  David Alsteens

  Frontiers in Biophysics

  doi 10.3389/frbis.2023.1215594