Review
Published
MeCP2 functions as a DNA methylation reader in immune homeostasis and cancer
Grace C. Stroman · Clara Mellows · Kevin Pruitt
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1917394
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 50 articles
Review
Published
From chromatin to proteostasis: multilevel gene regulation in Mendelian diseases
Himanshu Goel · Gunjan Garg
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1944086
Review
Published
Circular RNAs: from transcriptional noise to engineered therapeutics
Aaron C. Chack · Chad V. Pecot
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1894220
Original Research
Published
Arsenic induced Hippo pathway dysregulation linked to hTERT hypo-methylation in breast cancer patients
Archana Chaudhary · Manish Kumar · Lalit Mohan · Abhay Kumar · Rishikesh Kumar · Shailesh Kumar · Kumar Pranay · Nandani Kumari · Rizwanul Haque · Md. Margoob Ahmad
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1853054
Mini Review
Published
Phenotypic plasticity in fish cell lines: conceptual links to aquatic epigenetics
Daisuke Ikeda
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1867376
Methods
Published
Elucidation of chromatin loops among regulatory regions using Hi-TrAC
Yaqiang Cao · Qingsong Tang · Keji Zhao
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1858923
Review
Published
The microbiome and its impact on the epigenome in cancer
Akhil Kapoor · Rohit Kumar · Anuj Gupta · Bipinesh Sansar · Bal Krishna Mishra · Mahesh Chaudhary · Archi Rungta · Gopalakrishna Kallapura · Kumar Prabhash
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1857307
Original Research
Published
A placental DNA methylation score associated with early-onset preeclampsia and maternal vascular malperfusion pathology
Hannah J. Illing · Alexa A. Freedman · Lauren Keenan-Devlin · Gregory E. Miller · Ann E. Borders · Linda M. Ernst · Wendy P. Robinson
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1749513
Editorial
Published
Editorial: Epigenetics and metabolism: a closed liaison in tumor cells
Serena Castelli · Nicolò Mangraviti · Rohan Kodgule
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1886632
Systematic Review
Published
Environmental epigenetic modifiers in neurodegenerative diseases: a systematic review of epigenomic mechanisms and therapeutic targets
Pranay Wal · Sunita Mishra · Debashish Pradhan · Ankita Wal · Debashis Purohit · Lalit Mohan Nainwal · Vivek Dhir · Amin Gasmi
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1833533
Review
Published
Mobile small RNAs as mediators of stress-induced epigenomic remodeling and systemic stress adaptation
Muhammad Daniyal Junaid · Muhammad Shahzad Iqbal · Muhammad Waqar Nasir · Muhammad Waseem Akhter
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1827933
Review
Published
The pioneering work of Howard Cedar and his team in unraveling the roles DNA methylation plays in regulating genome function
Eugin Destici · Eric Mendenhall · Alon Goren
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1754553
Mini Review
Published
Epi-liquidomics: redefining cancer diagnostics through epigenetic profiling
Shahper Nazeer Khan · Mohammad Harris Siddiqui · Aamir Ahmad · Luca Guarnera · Salamatu Tijjani Isah
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1813822
Review
Published
The impact of epigenetics on tumor metabolism: Friend or foe in drug response?
Serena Castelli · Melania Franchini · Luigi Ferraro · Nicolò Mangraviti
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1755829
Mini Review
Published
Genomic and epigenomic landscape of ADPKD: towards precision diagnostics and tailored treatments
Amankeldi A. Salybekov · Aiman Kinzhebay · Sumi Hidaka · Shuzo Kobayashi
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1699528
Review
Published
Metabolic reprogramming and epigenetic effects due to reducing sugars and glycation products in cancer
Savita Bansal · Archana Burman · Taruna Arora · Meenakshi Vachher · Nalini Moza Wali · Bhupender Kumar
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1752493
Original Research
Published
Chromatin profiling for everyone: FFPE-CUTAC for the theory and practice of modern molecular biology
Yiling Xu · Steven Henikoff · Kami Ahmad
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1753710
Perspective
Published
Professor Emma Whitelaw, a pioneer of epigenetic inheritance
Alyson Ashe · Jessica J Hawes
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1733711
Original Research
Published
Comparison of enzymatic and bisulfite-based methods for sequencing-based cell-free DNA methylation profiling
Mark Ezegbogu · Peter Averill Stockwell · Glen Reid · Ben Brockway · Rajiv Kumar · Euan Rodger · Aniruddha Chatterjee
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1693925
Review
Published
Histones deacetylases in the epidermis: structure, functions and therapeutic implications
Chloé Nguyen Van · Jérôme Lamartine
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1711733
Original Research
Published
Epigenetic profiling of preterm birth: a dual-tissue methylation patterns using long-read sequencing
BalaSubramani Gattu Linga · Faisal E. Ibrahim · Aleem Razzaq · Muthanna Samara · Jameela Roshanuddin · Hind H. Adi · Aseel Al-Dewik · Ayla J. Ahmedoglu · Rand Hamdan · Amal E. I. Ahmed · M. Walid Qoronfleh · Hatem Zayed · Duaa Elshiekh · Mona Ellaithi · Mohamed Alsharshani · Palli Valapila Abdulrouf · Thomas Farrell · Bader Kurdi · Ghassan Abdoh · Hilal Al Rifai · Nader Al-Dewik
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1644521
Review
Published
Epigenetic dysregulation in pancreatic cancer: emerging biomarkers and clinical applications
Hina Sultana · Abhishikt David Solomon · Atif Khurshid Wani · Surendra K. Shukla
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1723159
Editorial
Published
Editorial: Epigenetic basis of circadian rhythm and metabolism
Rasime Kalkan · Peter S. Reinach · Zachary Harvanek · Dongsheng Yan
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1736716
Epigenetics and Epigenomics
Published
Epigenetic repurposing of carbohydrate metabolic inhibitors for insulin resistance: targeting DNMT1 and HDAC3 for β-cell restoration
Muhammad Javid Iqbal · Luis A. Salazar
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1691949
Epigenetics and Epigenomics
Published
Non-coding RNAs at the intersection of epigenetics and cancer metabolism
Nicolò Mangraviti · Serena Castelli
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1699969
Epigenetics and Epigenomics
Published
Cancer metabolism rewiring and chromatin methylation: a vulnerable epi-metabolic link
Sandra Atlante · Veronica Barbi · Carlo Gaetano · Barbara Illi
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1638572
Epigenetics and Epigenomics
Published
Pioneers of chromosome elimination
Luca Comai · Mohan Prem Anand Marimuthu
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1648270
Epigenetics and Epigenomics
Published
Discovery and structural studies of histone demethylases
Longfei Peng · Xinze Li · Hao Yang · Haonan Chen · Yue Yang · Shunfeng Peng
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1594400
Epigenetics and Epigenomics
Published
Epigenetic mechanisms of plasticity and resistance in glioblastoma: therapeutic targets and implications
Farzaneh Amirmahani · Saurav Kumar · Sree Deepthi Muthukrishnan
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1519449
Epigenetics and Epigenomics
Published
Hansemann’s anaplastic theory of cancer after 135 years
Steven Henikoff · Kami Ahmad
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1607433
Epigenetics and Epigenomics
Published
High-throughput, pan-leukocyte biomarkers for the detection of inflammation in human breastmilk and stool
M. J. Dunnet · I. M. Morison · D. M. Bond · T. A. Hore
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1535838
Epigenetics and Epigenomics
Published
Roles for epigenetics in wood formation and stress response intrees–from basic biology to forest management
Andrew Groover
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1476499
Epigenetics and Epigenomics
Published
Editorial: Current insights in Epigenetics and Epigenomics
Steven Henikoff · Sharon Y. R. Dent · Raul Mostoslavsky · Ting Wang · Luca Comai
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1566501
Epigenetics and Epigenomics
Published
Editorial: Epigenetics and genomic causality in development and chromatin research
Ellen V. Rothenberg · Ute Deichmann
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1564074
Epigenetics and Epigenomics
Published
Effects of entinostat, quisinostat, and tubastatin-A on alcohol consumption in male high ethanol consuming rats
Sheketha R. Hauser · Laura B. Ferguson · Tiebing Liang · Erin E. Jarvis · R. Dayne Mayfield · Richard L. Bell
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1503093
Epigenetics and Epigenomics
Published
Lineage- and stage-specific activity of antigen receptor gene enhancers during lymphocyte development
Fei Ma · Fatima Zohra Braikia · Ranjan Sen
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1489362
Epigenetics and Epigenomics
Published
HDAC3 regulates the diurnal rhythms of claudin expression and intestinal permeability
Hunter Christopher · Jianglin Zhang · Sarah Olanrewaju Oladejo · Samskrathi Aravinda Sharma · Zheng Kuang
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1496999
Epigenetics and Epigenomics
Published
The impact of climate change-related disasters on mental health and epigenetics: a narrative review
Emma Antonina Roe · Engluy Khov · Hannah Kim · Beth Demelo · Savannah Zavitz · Lei Cao-Lei
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1464276
Epigenetics and Epigenomics
Published
MicroRNAs provide negative feedback and stability in gene regulatory network models of cell-state transitions
Milad Razavi-Mohseni · Michael A. Beer
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1473789
Epigenetics and Epigenomics
Published
Blood DNA methylation of CRF and its association with amygdala volume and mood in Cushing’s syndrome
Richard S. Lee · Alicia Santos · Henri Garrison-Desany · Anna Aulinas · Jenny L. Carey · Yolanda Vives-Gilabert · Olivia H. Cox · Gabriel Cuilan · Susan M. Webb · Eugenia Resmini
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1435634
Epigenetics and Epigenomics
Published
Regulation of developmentally controlled enhancer activity by extrinsic signals in normal and malignant cells: AP-1 at the centre
Alexander Maytum · Nadine Obier · Pierre Cauchy · Constanze Bonifer
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1465958
Epigenetics and Epigenomics
Published
Interplay between epigenetics and metabolism controls cancer stem cell plasticity
Jee-Eun Choi · Inwha Baek
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1424163
Epigenetics and Epigenomics
Published
Quantification of tumour-infiltrating immune cells through deconvolution of DNA methylation data in Ewing sarcomas
Sara Patrizi · Silvia Vallese · Lucia Pedace · Claudia Nardini · Alessandra Stracuzzi · Sabina Barresi · Isabella Giovannoni · Luana Abballe · Celeste Antonacci · Ida Russo · Angela Di Giannatale · Rita Alaggio · Franco Locatelli · Giuseppe Maria Milano · Evelina Miele
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1427399
Epigenetics and Epigenomics
Published
Transgenerational epigenetic inheritance: a critical perspective
Adrian Bird
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1434253
Epigenetics and Epigenomics
Published
Histone H2A variants play a key role at DNA double-strand breaks during repair pathway choice
Emile Clerf · Maxime Galloy · Amélie Fradet-Turcotte · Jacques Côté
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1445765
Epigenetics and Epigenomics
Published
A hypothetical model: Chromatin remodelers couple with acetyltransferases to trigger the elongation of RNA polymerase II (pol II)
Gongyi Zhang
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1439973
Epigenetics and Epigenomics
Published
Subcellular one carbon metabolism in cancer, aging and epigenetics
Tiziano Bernasocchi · Raul Mostoslavsky
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1451971
Epigenetics and Epigenomics
Published
Benchmark of the Oxford Nanopore, EM-seq, and HumanMethylationEPIC BeadChip for the detection of the 5mC sites in cancer and normal samples
Kseniia A. Deinichenko · Valentina G. Vynogradskaya · Pavel A. Grebnev · Valeriya M. Mikova · Dmitriy O. Bobylev · Abusaid M. Shaymardanov · Alexey A. Ivashechkin · Marina V. Erokhina · Alexandra I. Akinshina · Anna V. Semyanihina · Sergey I. Mitrofanov · Konstantin S. Grammatikati · Vladimir S. Yudin · Sergey M. Yudin · Antonida V. Makhotenko · Anton A. Keskinov · Sergey A. Kraevoy · Anna S. Makarova · Ekaterina A. Snigir · Dmitry V. Svetlichnyy · Veronika I. Skvortsova
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2024.1362926