Mini Review
Published
The impact of aging, sex, and exercise on brain mitochondria
Jianhua Zhang · Victor Darley-Usmar · Yun Li
Frontiers in Aging
doi 10.3389/fragi.2026.1920914
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Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 52 articles
Mini Review
Published
Mapping the neural basis of the perception of “flow of time”: interval timing and mental time travel in the human brain
Ryuta Ochi · Mitsuru Kawamura
Frontiers in Neurology
doi 10.3389/fneur.2026.1960572
Editorial
Published
Editorial: Imaging biomarkers in neurodegenerative diseases: advances and challenges
Francesco Lanfranchi · Andrew R. Bender · Lucas Caldi Gomes
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.2009935
Mini Review
Published
Molecular mechanisms underpinning cognitive reserve and resilience
Amber Chen · Sreenithi Bhuvaneshwaran · Yash Akkara · Thomas Burke · Robert Perneczky · Magdalena Sastre
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1957901
Review
Published
Deep brain stimulation and spinal cord stimulation for chronic disorders of consciousness: a decade of clinical evidence, mechanistic insights, and critical appraisal
Dongsheng Liu · Kai Yang · Jianlei An · Sipeng Zhu · Yitong Jia · Yichen Zhou · Yong Wang · Weihua Cheng · Kaihan Jiang · Yi Yang · Shaoya Yin · Lei Liu
Frontiers in Human Neuroscience
doi 10.3389/fnhum.2026.1982589
Review
Published
The potential of AI inspired approaches for patient monitoring in drug development for Huntington’s disease: capturing the digital exhaust for activities of daily living
Amit Khanna · Graham Jones
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2026.1966010
Review
Published
Loss of microbial diversity from human–microbe coevolution: immune, epigenetic, and enteric nervous system mechanisms linking dysbiosis to neuropsychiatric and neurodegenerative diseases
Hajar Heidari · Michael Brimacombe · David A. Lawrence
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1952549
Mini Review
Published
The cochlear macrophage in presbycusis: inflammaging, neuroinflammation, and targets for therapeutic modulation
Reef K. Al-Asad · Judith S. Kempfle
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1930209
Original Research
Published
Network-level restoration of impaired memory function in early Alzheimer’s disease via GluN2B modulation: insights from a hippocampal CA1–CA3 model
Fabio Librizzi · Saana Seppälä · Marja-Leena Linne · Michele Migliore · Ausra Saudargiene
Frontiers in Computational Neuroscience
doi 10.3389/fncom.2026.1953352
Perspective
Published
Neuroimmune phenotypes in brain aneurysms and neurodegenerative diseases
Francis J. Lauzier · David C. Lauzier
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1916561
Review
Published
Telomeric autophagy in human health, aging, and diseases
Xingyao Li · Xili Wu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1922188
Original Research
Published
Therapeutic prospects of Annona crassiflora based on in vitro and in silico approaches
Lúcia Pinheiro Santos Pimenta · Gisele Avelar Lage · José Dias de Souza Filho · Alan Rodrigues Teixeira Machado · Vera Lúcia Almeida · Júlio Cesar Dias Lopes
Frontiers in Natural Products
doi 10.3389/fntpr.2026.1907968
Review
Published
Expression and role of HSPA5 in environmental toxin-induced neurological disorders
Yurong Wang · Yang Lv · Ruidong Zhao · Xin Guo · Jing Gao · Tong Wang · Dongmei Yao · Xin Li · Bingchun Liu · Jianlong Yuan
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1964213
Brief Research Report
Published
Assessment of microexon-associated junction usage in Parkinson’s disease and spinocerebellar Ataxia type 3
Kira Mehnert · Jeannette Hübener-Schmid · Jakob Admard · Vladislav Lysenkov · German Demidov · Chrisovalantou Huridou · Jonasz Jeremiasz Weber · Olaf Riess · Nicolas Casadei
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1872346
Review
Published
Mitohormesis linking metabolic dysfunction and neurodegeneration: implications for dementia and therapeutic strategies
Toshiki Otoda · Hideto Nakajima · Tadateru Takayama
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1892506
Original Research
Published
Rational discovery of peptide inhibitors targeting Keap1: a focus on neurodegenerative diseases
Nandhini Senthilkumar · Shanthi Veerappapillai
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1929781
Correction
Published
Correction: Reward contingency reorganizes lateral orbitofrontal cortex pyramidal neuron activity from reward-aligned to action-aligned during associative learning
Zicheng Yang · Xiaolan Chen · Xiaohong Sun · Huimeng Lei
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1987114
Mini Review
Published
At the nucleus of neuronal health: Drosophila insights into LaminB-dependent homeostasis in aging and cell death
Francesco Napoletano
Frontiers in Cell Death
doi 10.3389/fceld.2026.1954383
Mini Review
Published
Recent advances in mass spectrometry methods for the investigation of oligomeric intermediates of amyloid protein aggregation
Carlo Santambrogio · Erika Ponzini · Frank Sobott · Rita Grandori
Frontiers in Biophysics
doi 10.3389/frbis.2026.1939530
Systematic Review
Published
Mapping intersectionality in dementia care research: a decadal scoping review
Martina Roes · Franziska Laporte Uribe · Simone Anna Felding · Georgina Charlesworth · Nicole Müller · Saloua Berdai · Jem Bhatt · Kuebra Altinok · Viktoria Peters-Nehrenheim
Frontiers in Dementia
doi 10.3389/frdem.2026.1779670
Review
Published
The effects of abused drugs on ferroptosis pathways: potential therapeutic targets for substance use disorders
Tamara Bouchard · Brooke Russell · Liam Liyang Guo · Tina Nguyen · Yan Cheng · Yan Y. Sanders · Ming-Lei Guo
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1899553
Review
Published
Pollutants regulate changes in pathological markers of neurodegenerative diseases: a new perspective in environmental toxicology
Xingbo Kou · Qianqian Hu · Yibo Kou · Dinghao An
Frontiers in Toxicology
doi 10.3389/ftox.2026.1814795
Original Research
Published
Evaluating the correspondence of neuropsychological profiles with clinical diagnostic criteria for frontotemporal lobar degeneration and Alzheimer's disease: insights from k -means clustering
Marie Söntgerath · Simone Cutini · Angelika I. T. Thöne-Otto · Annerose Engel · Frank Regenbrecht · Maryna Polyakova · Karsten Mueller · Nico Scherf · Fabiola Boehm · Sarah Anderl-Straub · Bernhard Landwehrmeyer · Adrian Danek · Janine Diehl-Schmid · Klaus Fassbender · Klaus Fliessbach · Holger Jahn · Holger Kornhuber · Martin Lauer · Johannes Prudlo · Matthis Synofzik · Jens Wiltfang · Markus Otto · Matthias L. Schroeter
Frontiers in Dementia
doi 10.3389/frdem.2026.1757680
Original Research
Published
In silico prediction of the permeability of phytochemicals across the blood-brain barrier
Diogo Carregosa · Iris Moreira · Diogo Rasteiro · Leonardo Vanneschi · Cláudia Nunes dos Santos
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1939611
Original Research
Published
Primary cell and tissue cultures of human choroid plexus epithelial cells
Ronja Bihlmaier · Melanie Scharr · Peter H. Neckel · Bernhard Hirt · Andreas F. Mack
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1827493
Editorial
Published
Editorial: Computational approaches to neurodegenerative diseases
Milos Antonijevic
Frontiers in Computational Neuroscience
doi 10.3389/fncom.2026.1952655
Original Research
Published
Rotenone-induced oxidative stress triggers peroxisomal alterations in BV-2 microglial cells
Alessio Valenza · Maurizio Muzzi · Francesca Rendina · Irene Montali · Daniele Pensabene · Anna Fracassi · Marco Segatto · Sandra Moreno
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1941513
Original Research
Published
Reward contingency reorganizes lateral orbitofrontal cortex pyramidal neuron activity from reward-aligned to action-aligned during associative learning
Zicheng Yang · Xiaolan Chen · Xiaohong Sun · Huimeng Lei
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1850197
Review
Published
From metabolism to neurodegeneration: how microglial functional reprogramming drives neurodegenerative diseases
Qiaoqiao Cui · Ke Zheng · Qiyun Liu · Lizhen Wang · Yixin Liu · Ruifang Bai · Wei Zhang · Junhong Guo · Xueli Chang · Juan Wang
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1921079
Original Research
Published
Gap junction protein connexin 36 proteostatic mechanisms in photoreceptor cells subjected to excitotoxic stress
Monika Katan · Klaudia Mróz · Joanna Lewin-Kowalik · Adrian Smędowski
Acta Biochimica Polonica
doi 10.3389/abp.2026.16091
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Systematic Review
Published
Premature and early menopause and neuroimaging biomarkers of neurodegenerative diseases: a systematic review
Emily Gallmetzer · Elijah Mak · Firat Kara · Burcu Zeydan · Ekta Kapoor · Chrisandra L. Shufelt · Walter A. Rocca · Kejal Kantarci
Frontiers in Dementia
doi 10.3389/frdem.2026.1912295
Review
Published
Zebrafish as a translational model for peptide-mediated synaptic dysfunction related to obesity
Amanda Costa Rodrigues · Adriel Parahyba Lacerda · Lincoln Takashi Hota Mukoyama · Gleyce Barrios de Carvalho · Júlia Aparecida Lima da Mata · Danieli Fernanda Buccini · Octavio Luiz Franco · Ludovico Migliolo
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2026.1845252
Review
Published
Bioactive constituents of Hericium erinaceus: extraction strategies, health benefits and food applications
Vibhuti Gurung · Narashans Alok Sagar · Nitu Rani
Frontiers in Natural Products
doi 10.3389/fntpr.2026.1872464
Correction
Published
Correction: Automated ROI detection allows rapid quantification of synaptic activity across tens of thousands of synapses in cell culture
John Carl Begley · Harald Prüss · Paul Turko · Camin Dean
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2026.1904571
Hypothesis and Theory
Published
Neuroinflammation as a failure of allostatic integrity: a hierarchical-circular model of biological memory for pathogenesis in neurodegenerative and neuropsychiatric diseases
Samuel Ruesga Mundo
Frontiers in Systems Neuroscience
doi 10.3389/fnsys.2026.1888548
Review
Published
The nano-neuro nexus: smart sensors at the frontier of detecting neurodegeneration
Arpit Mehrotra · Abhilasha Sood · Shraddha Yadav · Aditi D. Raval · S. Renuka Jyothi · Ashok Kumar Sah · Chandan Sharma · Laxmidhar Maharana
Frontiers in Nanotechnology
doi 10.3389/fnano.2026.1843615
Review
Published
Post-translational modifications as a regulatory code for tau function in health and disease
Abigail J. Nordbeck · Bhirisha Sharma · Charles A. Garcia · Jui-Heng Tseng
Frontiers in Dementia
doi 10.3389/frdem.2026.1834737
Review
Published
Revisiting the clastosome: a stress-induced nuclear proteolytic compartment of mammalian cells
Miguel Lafarga · María T. Berciano · Noemí Rueda · Sofía Cardona-Cortés · Olga Tapia
Frontiers in Neuroanatomy
doi 10.3389/fnana.2026.1839944
Systematic Review
Published
Environmental epigenetic modifiers in neurodegenerative diseases: a systematic review of epigenomic mechanisms and therapeutic targets
Pranay Wal · Sunita Mishra · Debashish Pradhan · Ankita Wal · Debashis Purohit · Lalit Mohan Nainwal · Vivek Dhir · Amin Gasmi
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1833533
Original Research
Published
Automated ROI detection allows rapid quantification of synaptic activity across tens of thousands of synapses in cell culture
John Carl Begley · Harald Prüss · Paul Turko · Camin Dean
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2026.1832103
Case Report
Published
Case Report: A converging pathology: Chediak–Higashi syndrome and IEI-associated lymphoproliferative disease
Carlos R. Varón · Santiago Andrés Suárez-Gómez · Daniela Varón · Libelly Gómez Flórez · Carolina Cortes-Urrea · Elda Graciela Vélez Colmenares · Isabella Corona
Frontiers in Hematology
doi 10.3389/frhem.2025.1650494
Photonics
Published
Light-induced secretion and transformation of neurotransmitter dopamine
Shuanghong Wei · Chang Liu · Zuomeng Wu · Jianmin Si · Xingxing Huo · Cailiang Shen · Yi Zhen · Dongwei Liu · Lei Chen
Frontiers in Photonics
doi 10.3389/fphot.2025.1647467
Neuroscience
Published
AMPA receptors in the evolving synapse: structure, function, and disease implications
Fleming Francis · Dewan Chettri · Deepak Nair
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2025.1661342
Biophysics
Published
Proton channel Hv1 modulates microglial responses to neurological disorders
Maite Stratmann · Caterina Gagliardi · Melania Capasso
Frontiers in Biophysics
doi 10.3389/frbis.2025.1681011
Drug Delivery
Published
Strategies for delivering drugs across the blood-brain barrier for the treatment of neurodegenerative diseases
Xiaopei Zhang · Manfei Fu · Yuanfei Wang · Tong Wu
Frontiers in Drug Delivery
doi 10.3389/fddev.2025.1644633
Molecular Medicine
Published
Neural stem cells in adult neurogenesis and their therapeutic applications in neurodegenerative disorders: a concise review
Teketay Bayleyegn Derso · Bemrew Admassu Mengistu · Yitayew Demessie · Melkie Dagnaw Fenta · Kalkidan Getnet
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2025.1569717
Molecular Medicine
Published
Epigenetic regulation of TDP-43: potential implications for amyotrophic lateral sclerosis
D. Y. Mengistu · M. Terribili · C. Pellacani · L. Ciapponi · M. Marzullo
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2025.1530719
Molecular Medicine
Published
Human-specific gene ARHGAP11B —potentially an additional tool in the treatment of neurodegenerative diseases?
Wieland B. Huttner
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2024.1465647