Mini Review
Published
Immunotechnology-based toolbox for care of chronic wounds
Munishwar Nath Gupta · Premlata Ambre
Frontiers in Biomaterials Science
doi 10.3389/fbiom.2026.1979352
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 121 articles
Original Research
Published
Explainable machine learning integrating CT-derived intratumoral heterogeneity for histological subtype prediction in pure ground-glass lung adenocarcinoma: multicenter validation and transcriptomic characterization
Ying Deng · Jiajun Liu · Dinghua Li · Bingyi Zhang · Bin Xiang · Wanyin Qi · Sanhong Zhang
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1958127
Review
Published
Copper complexes in the triple-negative breast cancer landscape: advances and opportunities
Paula Marynella Alves Pereira Lima · André Carlos Pereira de Matos · Gabriela da Silva Guimarães · Laryssa Aparecida Sales Barbosa · Thaise Gonçalves Araújo
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1931263
Mini Review
Published
Iron homeostasis at the interface of nutrition, infection, and iron supplementation
Özge Mert · Seray Saday · Aybala Temel
Frontiers in Nutrition
doi 10.3389/fnut.2026.1943495
Original Research
Published
Low-affinity anti-HER2-CAR T cells efficiently eradicate HER2 + and HER2 low cancer cells with reduced toxicity on healthy tissue
Leonard Knoedler · Konstantin Herfeld · Julian N. Scherer · Kaiji Fan · Dhyani Shah · Sascha Goettert · Luisa Becker · Iria Lloshi · Suqi Li · Dennis C. Harrer · Matthias A. Fante · Tobias Wertheimer · Roland Schelker · Severin Guetter · Misbah Tariq · Omer Khalid · Alexander Scheiter · Wolfgang Herr · Christian Schmidl · Moritz Jesinghaus · Markus Tschurtschenthaler · Hendrik Poeck · Markus Perl
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1895507
Systematic Review
Published
The CXCL12/CXCR4 axis in breast cancer-associated fibroblasts: a transcriptome analysis and systematic literature review
Sergey Vladimirov · David Sergeevichev · Maria Bogachek · Alina Kazakova · Anastasia Leonteva · Vladimir Richter · Anna Nushtaeva
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1920541
Original Research
Published
Multi-cohort screening of PANoptosis-related genes reveals PARP1 as a key target, and AZD5305 exerts anti-tumor effects in neuroblastoma
Shujun Shi · Zhaoxia Zhang · Junyi Luo · Zhaoying Wang · Tao Mi · Liming Jin · Xiangpan Kong · Jinkui Wang · Junhong Liu · Li Wang · Dawei He
Frontiers in Oncology
doi 10.3389/fonc.2026.1903085
Review
Published
Extracellular vesicles in colorectal cancer: M2 polarization, bidirectional regulation of CAFs, metastasis, and treatment
Xiaoling Wang · Zhaohua Lai · Hanlu Chen · Mei Yang · Huapei Kang · Fangsheng Wang · Junyun Huang · Yuxin Deng
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1980961
Review
Published
Glutamine metabolic reprogramming in acute and chronic kidney diseases: mechanistic insights and therapeutic implications
Ruotong Xu · Jin Zhao · Minna Liu · Yifan Qiao · Xiaoxuan Ning · Shiren Sun
Frontiers in Immunology
doi 10.3389/fimmu.2026.1939528
Mini Review
Published
T-cell metabolic reprogramming in systemic lupus erythematosus: linking intracellular metabolism to effector differentiation and senescent-like/exhausted-like states
Yi Zou · Zhichu Ren · Yuki Kudo · Michihito Kono
Frontiers in Immunology
doi 10.3389/fimmu.2026.1961063
Original Research
Published
Spatial analysis of placentae during congenital cytomegalovirus infection suggests distinct cellular profiles in immune and trophoblast cells: an exploratory study
Elise Sintim-Aboagye · Huy Quang Quach · Indrani Mukherjee · Will Sherman · Katelyn T. Nguyen · Neil Ferland · Sheila Farnan · Kamila Otrubova · Namisha Verma · Dawn Littlefield · Sohan Punia · Erica Johnson · Mark Blackstad · Mark R. Schleiss · Andrew P. Norgan · Clive M. Gray · Elizabeth Ann L. Enninga · Rana Chakraborty
Frontiers in Immunology
doi 10.3389/fimmu.2026.1885923
Systematic Review
Published
Global trends and hotspots of genetic research on non-syndromic cleft lip with or without cleft palate: a bibliometric and bioinformatics analysis
Yuxuan Shang · Mingjian Zhao · Shuangshuang Gao · Shikang Gao · Mengru Zhu
Frontiers in Genetics
doi 10.3389/fgene.2026.1907333
Review
Published
Flavonoids in cancer pharmacology: molecular mechanisms, tumor microenvironment regulation, and drug resistance
Zhengyuan Yu · Zhanyi Zhou · Ni Yin · Hongcheng Ge
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1969337
Original Research
Published
Selective inhibition of aldosterone production modulates human adrenocortical (HAC15) cell fate
Kha Chin Long · Amnani Aminuddin · Najiah Ajlaa Ayub · Geok Chin Tan · A. Rahman A. Jamal · Nor Azian Abdul Murad · Nor Adzimah Johdi · Celso E. Gomez-Sanchez · Norlela Sukor · Morris J. Brown · Elena A. Azizan
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1872432
Case Report
Published
Amelanotic subungual melanoma becoming clinically apparent within 24 h after minor blunt trauma: a case report
Huiru Wang · Peng Wang · Yanyan Suo · Kang Lu · Qingfeng Xue · Huahua Li · Rui Gao · Yunchang Guo · Songjia Qu · Xiaowei Cai
Frontiers in Medicine
doi 10.3389/fmed.2026.1991898
Original Research
Published
Study on the promoting effect of microplastic exposure on prostate cancer migration and invasion based on network toxicology and single-cell sequencing technology
Haiyang Jiang · Ying Bi · Longguo Dai · Yong Zhu · Ruikang Zhang · Chen Hu · Hong Yang · Jun Li · Chongjian Zhang · Yu Bai · Ruiqian Li
Frontiers in Oncology
doi 10.3389/fonc.2026.1973812
Original Research
Published
Cross-species transcriptomic plasticity and root architectural adaptations in Brachypodium ( Brachypodium distachyon ) and barley ( Hordeum vulgare ) genotypes under different ammonium and nitrate availability
Hamid Rouina · Dilkaran Singh · Christopher Arlt · Amy Marshall-Colon · Benjamin Stich
Frontiers in Plant Science
doi 10.3389/fpls.2026.1916213
Mini Review
Published
The role of platelet-rich plasma in repeated implantation failure: a review of biological mechanisms and clinical efficacy
Fanourios Makrygiannakis · Thomas Vrekoussis · Maria Marmara · Aikaterini Berdiaki · Antonis Makrigiannakis
Frontiers in Reproductive Health
doi 10.3389/frph.2026.1907558
Original Research
Published
Regulatory role and mechanism of sRNA24 targeting pqsH in Pseudomonas aeruginosa infection immunity
Huanlan Liao · Qianying Liu · Yuyang Liu · Qiwei Li · Yujuan Xiong · Lan Wang · Yang Lu
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1933779
Original Research
Published
Pathway-level analysis suggests a maintenance-oriented transcriptional response of the ammonia-oxidizing bacterium Nitrosospira sp. NT to acidic pH
Yuxiang Song · Zhongjun Jia
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1957381
Mini Review
Published
Metabolic rewiring at the obesity–estrogen–polyamine axis in endometrial cancer: emerging mechanisms and translational opportunities
Daniel Simancas-Racines · Dolores Jima Gavilanes · Andri Matos · Gabriele Davide Bigoni-Ordóñez · Claudia Reytor-González
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1954981
Original Research
Published
Gypenoside LI modulates autophagy-associated apoptosis in clear cell renal cell carcinoma by PPARG/PTEN/PI3K/AKT/mTOR/ULK1 signaling network
Ruyi Liu · Hao Yu · Hui Liu · Yujie Wei · Anxin Wang · Qi Huang · Hui Xu · Xiuming Li
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1956477
Original Research
Published
Astrocyte maturation creates a stage-specific niche that instructs hippocampal neurogenesis
Evangelia Masouti · Lucía Casares-Crespo · Andreas Sagner · Arne Gessner · Martin F. Fromm · Helena Mira · Ruth Beckervordersandforth
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1966983
Original Research
Published
A Caribbean bright spot coral reef exceeds thermal limits during the fourth global coral bleaching event
Sophie Carolan · Katherine C. R. Baldock · Holly East · Clare Fitzsimmons · Jamie A. Johnson · Andrew J. Suggitt · James R. Guest
Frontiers in Marine Science
doi 10.3389/fmars.2026.1913019
Perspective
Published
How AI-based techniques for brain tumour diagnosis can address data variability
Paola Lecca · Michela Lecca
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1916468
Review
Published
Carbon dots in tissue repair: from cell behavior to microenvironment remodeling
Xumin Li · Junsi Luo · Shuangjiang Li
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1912437
Mini Review
Published
TRIM22 in cancer: a context-dependent E3 ligase at the interface of interferon, p53, and tumor plasticity
Chenjie Qiu · Liangliang Dai
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1977247
Original Research
Published
An entosis-informed prognostic index for survival stratification and molecular characterization in lung adenocarcinoma
Yinqin Liu · Wen Zhao · Shuyi Mu · Silun Liang · Yanping Wen · Shaobin Li · Chengyan Zhan · Yanqi Cheng · Ling Tang · Yuqin Wu · Ziyou Lin · Hong Fang · Yubin Ding
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1943127
Review
Published
Intelligent defense at the edge: a comprehensive survey of federated learning, TinyML and explainable AI for intrusion detection in IoT and IIoT ecosystems
S. Sarath Kumar · M. Asha Jerlin
Frontiers in Artificial Intelligence
doi 10.3389/frai.2026.1900815
Original Research
Published
Social media use and cosmetic surgery consideration among Chinese university students: a cross-sectional test of serial mediation through beauty ideal internalization and self-objectification
Xiujie Zhou · Danni Dai · Zhen LV · Fanghao Xiao · Chenyu Wang · Jianchao Ni
Frontiers in Communication
doi 10.3389/fcomm.2026.1932859
Original Research
Published
Molecular mechanism of dynamic regulation of the proNGF/NGF ratio in controlling hair follicle cycle transition in liaoning cashmere goats
Bing Luo · Di Han · Meng Sun · Jianwei Wei · Mingqian Li · Shuai Chang · Zhiguo Quan · Ying Wang · Chunqiang Wang · Wei Ma
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1940416
Original Research
Published
ALYREF regulates glycolysis and promotes the progression of endometrial cancer through m 5 C modification of PKM2 mRNA
Yun Feng · Xueyin Li
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1831562
Original Research
Published
Longitudinal single-cell analysis identifies a chemotherapy-suppressed proliferative program associated with adverse prognosis in neuroblastoma
Aiguo Zhu · Jian Wang
Frontiers in Genetics
doi 10.3389/fgene.2026.1878093
Original Research
Published
Bacterial actin MreB as a new antibiotic target
Emőke Bódis · Beáta Longauer · András Lukács · Tamás Huber · Miklós Nyitrai · Géza Makkai · Tibor Jánosi · Rita Börzsei · Csaba Hetényi · Zoltán Gazdag · Szilvia Barkó
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1912759
Original Research
Published
Xeno-free production of lentiviral particles: implementing hPL as FBS replacement in cell culture
Mariana Soares Guedes · Marnie Cole · Daniela Yildiz
Frontiers in Toxicology
doi 10.3389/ftox.2026.1903400
Original Research
Published
Serum exosomal DDX17 in the diagnosis and action mechanism of hepatocellular carcinoma
Defa Huang · Minghong Zhao · Meijin Liu · Tao Chen · Zihao Chen · Yuhuan Xie · Haiyang Yu · Shuqian Zhong · Junyun Huang · Dingyu Rao
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1897138
Original Research
Published
Human acellular amniotic membrane loaded with hair follicle-derived cells promotes wound repair and appendage-like structure formation
Yanxin Jiang · Zhongwen Hou · Xichao Jian · Zeyao Tang · Yan Zhou · Xing Hu · Chengliang Deng · Shune Xiao
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1947836
Original Research
Published
Synovial fluid-derived extracellular vesicles modulate joint cell function in osteoarthritis
Alvaro Compañ · Vittoria Carrabs · María Luisa Ferrándiz · Antonio Silvestre · Ignacio Muñoz · María Carmen Carceller · María Isabel Guillén
Frontiers in Aging
doi 10.3389/fragi.2026.1894052
Methods
Published
Protocol for non-viral HDR-based CRISPR/Cas9 platform for small custom editing in primary T cells
Katariina Mamia · Anniken Solveig Matheson Sollano · Vanja Lundberg · Svetlana Vakkilainen · Eliisa Kekäläinen · Camilla Schalin-Jäntti · Eira Leinonen · Børre Fevang · Juha Grönholm · Timi Martelius · Shiva Dahal-Koirala · Emma Maria Haapaniemi
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1817322
Original Research
Published
Decoding user satisfaction during reading of pre-defined question–answer pairs: BCI approach using delta and gamma EEG
Wanjoo Park · Salma Mansour · Laehyun Kim · Mohamad Eid
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1934150
Review
Published
Community health worker denominations: a global review through the case of French Guiana
Cássio de Figueiredo · Marc-Alexandre Tareau · Claire Boceno · Maylis Douine · Cyril Rousseau · Mathieu Nacher
Frontiers in Health Services
doi 10.3389/frhs.2026.1898370
Original Research
Published
Refined protocol for quantifying hippocampal neurogenesis in organotypic slice cultures
Irem Akyel · Graham K. Sheridan
Experimental Biology and Medicine
doi 10.3389/ebm.2026.11165
Original Research
Published
Single-cell transcriptomic analysis identifies vascular smooth muscle cell transcriptional programs associated with human carotid plaque remodeling
Yi-Jie Lu · Xue-Guang Lin · Ting Wang · Fan-Xuan Huang · Ying Deng · Shuai Jiang · Jing Dong Tang · Bo Yu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1950061
Review
Published
Multifunctional Cu 2-x Se nanomaterials for cancer theranostics: recent advances, therapeutic mechanisms, and translational challenges
Jingchao He · Jiachao Xie · Yunxiao Peng · Haicheng Yu · Lina Chen · Xiaohong Wang · Haibo Sun
Frontiers in Chemistry
doi 10.3389/fchem.2026.1902573
Review
Published
Non-neoplastic histiocytic proliferations in bone marrow: a case series of uncommon morphologic findings
Melissa Ha · Shafagh Parsazad · Luke T. Dang · Elham Vali Betts · Denis M. Dwyre · Ananya Datta Mitra
Frontiers in Hematology
doi 10.3389/frhem.2026.1939019
Original Research
Published
The application of deep neural networks to the detection of lumbar hernias: results from the approaches based on convolutional networks and transformers
António Fernandes · João Pedro Mazuco Rodriguez · Susana Moleirinho · Irina Trofimenko · Ekaterina Guseva · Alexander Martinovich · Ilzane Maria de Oliveira Morais · Louise Bisolo · Luís Mendes Gomes · José Machado
Frontiers in Radiology
doi 10.3389/fradi.2026.1722312
Original Research
Published
Unraveling skeletal muscle senescence in an in vitro cell culture model
Kayo Moreira Bagri · Morgana Teixeira Lima Castelo-Branco · Claudia Mermelstein
Frontiers in Aging
doi 10.3389/fragi.2026.1866906
Original Research
Published
3-hydroxy-3-methylbutyrate (3H3MB) suppresses glioma growth and extends survival in mice
Rizwan Khan · Xingzi Lin · Francesco Marrocco · Ottavia Giampaoli · Alice Reccagni · Javeria Maqbool · Fabio Sciubba · Adriano Patriarca · Michele De Rosa · Alfredo Miccheli · Gabriele Favaretto · Fabrizio Antonangeli · Cristina Limatola · Giuseppina D’Alessandro
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1917452