Perspective
Published
Proposal to refine the mechanistic classification of chronic pain and corresponding clinical symptomatology
Jean-Pascal Lefaucheur
Frontiers in Pain Research
doi 10.3389/fpain.2026.1963056
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 1331 articles
Original Research
Published
Changes in exercise adherence during use of an e-health application in individuals with knee osteoarthritis
Mathilde Pelletier-Visa · Louise Jeannot · Bruno Pereira · Emmanuel Coudeyre · Charlotte Lanhers
Frontiers in Rehabilitation Sciences
doi 10.3389/fresc.2026.1900991
Clinical Trial
Published
Quantifiable ankle pump exercise monitoring for early postoperative rehabilitation after hip and knee arthroplasty: an exploratory randomized controlled trial
Jiquan Shen · Xinggao Wang · Changjian Zhou · Xiaoying Zhu · Huiyun Shen · Yuxuan Chen · Run Liu · Zhijun Ye · Bo Wang
Frontiers in Rehabilitation Sciences
doi 10.3389/fresc.2026.1933740
Brief Research Report
Published
Bridging stakeholder needs and technological capabilities to identify humanoid robot applications in rehabilitation: a case study in an ALS multidisciplinary care unit
Rachele Piras · Samuele Bordini · Riccardo K. Simi · Ilaria Consolo · Valentina Esposito · Claudia Cavaggion · Maddalena Feder · Maria Fossati · Giorgio Grioli · Antonio Bicchi · Christian Lunetta · Manuel G. Catalano
Frontiers in Robotics and AI
doi 10.3389/frobt.2026.1944029
Review
Published
The impact of clear aligners therapy on dental caries: a systematic review
Silvia Caruso · Arianna Viarchi · Domenico Ciavarella · Michele Tepedino · Sara Caruso · Roberto Gatto · Claudia T. Truppa · Antonella Mattei · Marco Severino
Frontiers in Dental Medicine
doi 10.3389/fdmed.2026.1920698
Review
Published
Role of lasers in restorative dentistry: a review and update
Rashed A. Alsahafi · Heba A. Mitwalli · Basil Almutairi · Khalid S. Almulhim · Haitham AlQuorain · Turki Alshehri · Mohammed M. Gad · Abdulrahman A. Balhaddad
Frontiers in Dental Medicine
doi 10.3389/fdmed.2026.1941265
Original Research
Published
Beyond the neck: long-term motor and non-motor outcomes of pallidal DBS in craniocervical dystonia
Matthew Remz · Pamela Zeilman · Samyukta Senthil · Rohini Kumar · Isabelle Gerzenshtein · Hikaru Kamo · Aparna Wagle Shukla
Dystonia
doi 10.3389/dyst.2026.16756
Original Research
Published
Longitudinal trends in antimicrobial resistance phenotypes in Pseudomonas aeruginosa: a seven-year study
Wael A. Alghamdi · Khalid M. Orayj · Ahmed R. N. Ibrahim · Marim A. Abdelsalam · Abdullah M. Alshehri
Frontiers in Antibiotics
doi 10.3389/frabi.2026.1912287
Original Research
Published
Beyond renal support: biological modulation across pathophysiological domains during continuous renal replacement therapy — a randomized pilot study
Fernando Sánchez-Morán · Salvador Pérez · Juan Sastre-Belloch · María Lidón Mateu-Campos
Frontiers in Nephrology
doi 10.3389/fneph.2026.1932419
Original Research
Published
Radiomic model versus R.E.N.A.L. nephrometry score for predicting the likelihood of undergoing partial nephrectomy in clear cell renal cell carcinoma
Fa-de Liu · Hui-li Yu · Du-jian Wang · Xiao-bing Ju · Yan-hao Yang
Frontiers in Urology
doi 10.3389/fruro.2026.1928982
Original Research
Published
Appropriateness of antibiotic prescribing in dental practice: results of two clinical audits conducted at a university hospital
Romain Lan · Célia Lento · Delphine Tardivo · Carole Siani · Thomas Giraud · Jean-Hugues Catherine · Florence Carrouel · Nadim Cassir · Manon Roche
Frontiers in Oral Health
doi 10.3389/froh.2026.1913184
Review
Published
Microelectrode arrays: from electrophysiology to integrated cancer treatment induced cardiotoxicity assessment
Neda Karami · Sebastian Knafl · Heinz D. Wanzenboeck · Sonia Prado-López
Frontiers in Electronics
doi 10.3389/felec.2026.1886715
Original Research
Published
A novel minimally humanized mouse model of aniridia for preclinical evaluation of CRISPR gene editing strategies
Seyedeh Zeinab Mirjalili Mohanna · Andrea J. Korecki · Pardis Kazemian · Tess C. Lengyell · Bethany A. Adair · Blair R. Leavitt · Elizabeth M. Simpson
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1910209
Original Research
Published
Association of concomitant laparoscopy with reproductive outcomes after hysteroscopic septum resection: a longitudinal cohort study
Yu Lu · Mi Su · Qinqin Yuan · Li He
Frontiers in Reproductive Health
doi 10.3389/frph.2026.1950477
Original Research
Published
Development and validation of machine learning models for predicting rehabilitation non-response after knee arthroplasty
Niclas J. Hubel · Ferdinand Prüfer · Walter Bily · David Schneider · Bernhard Holzner · Michael J. Fischer · Vincent Grote
Frontiers in Rehabilitation Sciences
doi 10.3389/fresc.2026.1930836
Brief Research Report
Published
Preliminary usability evaluation of a teleoperated humanoid robot for pediatric waiting-room observation: clinical and technical professionals’ perspectives
Antea Scrocco · Samuele Bordini · Riccardo Kristen Simi · Elisa Matteucci · Elena Beani · Giovanni Cioni · Eugenia Conti · Maria Chiara Di Lieto · Giorgio Grioli · Antonio Bicchi · Giuseppina Sgandurra · Manuel Giuseppe Catalano
Frontiers in Robotics and AI
doi 10.3389/frobt.2026.1943197
Original Research
Published
Cross-species gene expression analysis identifies a type I interferon-associated transcriptional signature in Tregs from atopic dermatitis
Naoya Kase · Hina Nakamura · Chizuru Nakakomi · Manami Shimakata · Mai Banno · Ryotaro Kanari · Yohsuke Harada
Journal of Cutaneous Immunology and Allergy
doi 10.3389/jcia.2026.17310
Systematic Review
Published
Targeted therapies in systemic lupus erythematosus: mechanistic insights and clinical evidence from phase II and III trials
João Francisco Abrantes · Marina Dueñas-Ochoa · Roni Meidan · David Isenberg
Frontiers in Lupus
doi 10.3389/flupu.2026.1829480
Review
Published
Towards safer and more effective hemotherapy: addressing critical unmet needs in restrictive and liberal blood transfusion strategies
Emmanuel Ifeanyi Obeagu
Frontiers in Hematology
doi 10.3389/frhem.2026.1913853
Original Research
Published
Improvement in peritoneal dialysis exit-site infection rates in an integrated health care system in the United States
Max T. Hukill · Andrea M. Yeung · Talha H. Imam
Frontiers in Nephrology
doi 10.3389/fneph.2026.1825353
Brief Research Report
Published
Assessment of microexon-associated junction usage in Parkinson’s disease and spinocerebellar Ataxia type 3
Kira Mehnert · Jeannette Hübener-Schmid · Jakob Admard · Vladislav Lysenkov · German Demidov · Chrisovalantou Huridou · Jonasz Jeremiasz Weber · Olaf Riess · Nicolas Casadei
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1872346
Original Research
Published
Robust information transfer calculation reveals dynamic networks during sleep arousal
Richard Hohmuth · Jakob J. Müller · Hagen Malberg · Martin Schmidt
Frontiers in Network Physiology
doi 10.3389/fnetp.2026.1930617
Original Research
Published
Multi-cohort machine learning identifies a ferroptosis-linked prognostic signature in lung adenocarcinoma
Rana Salihoglu
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1921468
Original Research
Published
Effects of exercise-induced gradual versus instant avatar transformation on muscle strength and sense of embodiment in patients with chronic low back pain and healthy adults
Yong-Hao Hu · Yuichiro Nakaso · Takuto Nakamura · Takafumi Kanaya · Masayuki Inoue · Yukiko Shiro · Takahiro Ushida · Takuji Narumi
Frontiers in Virtual Reality
doi 10.3389/frvir.2026.1869292
Clinical Trial
Published
Perioperative challenges: does smoking compromise high-flow nasal oxygen efficacy in obese Men? A randomised controlled trial
Huabing Wang · Chunyan Zhang · Lu Li · Yu Tian · Chao Chen
Frontiers in Anesthesiology
doi 10.3389/fanes.2026.1915310
Original Research
Published
Effect of systematic nursing intervention on perioperative ocular symptoms in refractive surgery patients: evaluation using the ocular surface disease index scale
Yidi Zhang · Ping Zhang · Ran Zhu · Xiumei Wu · Jincui Wei
Frontiers in Health Services
doi 10.3389/frhs.2026.1864071
Methods
Published
Learning from 30 years of systems thinking in healthcare
Christian von Plessen · Paul Batalden · Peter Lachman · Julie K. Johnson
Frontiers in Health Services
doi 10.3389/frhs.2026.1795979
Systematic Review
Published
An updated evidence-informed framework for dental sedation: drugs, routes, patient selection, monitoring, and emergency preparedness
Giath Gazal · Mohammad Zakaria Nassani · Sam Thomas Kuriadom · Kusai Baroudi
Frontiers in Oral Health
doi 10.3389/froh.2026.1915718
Original Research
Published
Effects of an outpatient pulmonary rehabilitation program on exercise capacity, muscle fatigue, dyspnea, and functional status in post-COVID-19 patients: non-randomized clinical trial
Miriã C. Oliveira · Paolo Capodaglio · Heren N. C. Paixão · Adriano L. Fonseca · Larissa R. Alves · Jairo B. S. Ribeiro Júnior · Rodrigo F. Oliveira · Tiago V. Fernandes · Daniel G. Marconi · Rodrigo A. C. Andraus · Deise A. A. P. Oliveira · Claudia S. Oliveira · Carlos H. M. Silva · Orlando A. Guedes · Wilson R. Freitas Júnior · Luis V. F. Oliveira
Frontiers in Rehabilitation Sciences
doi 10.3389/fresc.2026.1921478
Case Report
Published
Management of bone cement leakage after percutaneous vertebroplasty in a geriatric patient with multimorbidity: a case report
Shuai Liu · Dazhi Li · Xiaodong Wu · Yanming Li
Frontiers in Musculoskeletal Disorders
doi 10.3389/fmscd.2026.1846800
Brief Research Report
Published
Serum BDNF in subacute stroke: effects of a four-week aerobic exercise intervention in the PHYS-STROKE trial
Torsten Rackoll · Lea Doppelbauer · Konrad Neumann · Alexander Heinrich Nave
Frontiers in Stroke
doi 10.3389/fstro.2026.1897859
Original Research
Published
Predicting disease progression under a “treatment-naive” counterfactual scenario in a competing risks framework
Daniela Zugna · Nicolas Destefanis · Renata Zelic · Andreas Pettersson · Lorenzo Richiardi
Frontiers in Epidemiology
doi 10.3389/fepid.2026.1850482
Original Research
Published
Healing through faith: spirituality and shrine visitation as coping mechanisms among haemophilia patients in Kashmir—an interpretative phenomenological study
Shabnam Mushtaq · Wakar Amin Zargar · Fayaz Ahmad Paul
Frontiers in Health Services
doi 10.3389/frhs.2026.1802955
Review
Published
The future directions of CAR-T Cell therapy: unlocking the potential of immunotherapy in cancer treatment
Angel Alberto Justiz-Vaillant · Sachin Soodeen · Rodolfo Arozarena-Fundora · Patrick Eberechi Akpaka · Chandrashekhar Unakal
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2026.1931159
Original Research
Published
Struggling together in a safe place: therapists’ perspectives on the therapeutic relationship in gameChange VR therapy
Andreas Seierstad · Helen Bull · Petter Brevik · Karine Bryn · Heena Yasmin · Andre Løvgren · Jan Ivar Røssberg · June Ullevoldsæter Lystad
Frontiers in Virtual Reality
doi 10.3389/frvir.2026.1898848
Study Protocol
Published
Challenges associated with sexually transmitted infection partner notification approaches in Africa: a scoping review protocol
Noluthando Mpobole · Raikane James Seretlo · Keatlegile Moses Eskia Mabena · Hanlie Smuts · Mathildah Mpata Mokgatle
Frontiers in Reproductive Health
doi 10.3389/frph.2026.1951049
Case Report
Published
Persistent refractory hypercapnia following tracheostomy decannulation in a patient with brainstem hemorrhage: a case report
Yunhong Deng · Fuqiang Wang · Yaojiang Li · Dongzhen Xue · Jinfeng Liang · Hanbo Chen · Wenying Xie · Bizhou Fu · Man Hao
Frontiers in Rehabilitation Sciences
doi 10.3389/fresc.2026.1874164
Original Research
Published
Residual hearing and sound quality in cochlear implant patients
Anika S. Walia · Nolan Chiles · Lauren O'Brien · Daniel Uralov · Thomas Willcox · Rebecca Chiffer · Jacob B. Hunter
Frontiers in Audiology and Otology
doi 10.3389/fauot.2026.1913231
Original Research
Published
Factors associated with common mental disorder symptoms and lived experiences among adults with hypertension in Nepal: a mixed-methods study
Lisasha Poudel · Binita Acharya · Bipsana Shrestha · Shreya Shrestha · Archana Shrestha · Buna Bhandari · Brandon A. Kohrt · Dristy Gurung · Sauharda Rai
Frontiers in Epidemiology
doi 10.3389/fepid.2026.1769884
Perspective
Published
Global challenges for lens and cataract research
Michael Wormstone
Frontiers in Ophthalmology
doi 10.3389/fopht.2026.1949916
Study Protocol
Published
Effectiveness of mobile text messages v/s traditional health education on improving knowledge about oral cancer at a primary dental health care center, Cuttack, Odisha: a randomized controlled trial protocol
Amaranath Behera · Hemamalini Rath · Utkal Kesari Mohanty · Gaurav Sharma · Saharsh Vir Jha · Krishnapriya Sekar · Anisha Dutta · Sharmistha S. Udgata · Saroj Kumar Behera · Subham Baroi · Satyaprabha Rout · Payal Maharana
Frontiers in Oral Health
doi 10.3389/froh.2026.1922583
Original Research
Published
Nationwide epinephrine auto-injector dispensing in Greece: a drug-utilization study providing insights into anaphylaxis epidemiology and emergency-treatment preparedness
George N. Konstantinou
Frontiers in Allergy
doi 10.3389/falgy.2026.1906574
Brief Research Report
Published
Developing a spherical video-based virtual reality program to facilitate embodiment: a proof-of-concept study
Nancy A. Baker · Alexandro Guerrero · Robert R. Edwards
Frontiers in Virtual Reality
doi 10.3389/frvir.2026.1878621
Original Research
Published
Role of essential and trace elements in chronic myeloid leukemia: associations with serum trace element profiles and hematological parameters
Ajay Kumar Yadav · Umesh Choudhary · Anupam Aich · Lalit Prashant Meena · Royana Singh · Shivam Tiwari · Ashish Ashish
Frontiers in Aging
doi 10.3389/fragi.2026.1920709
Brief Research Report
Published
Patient knowledge and views on the health impacts of climate change in primary care: a cross-sectional survey study
Melanie S. Stewart · Sahil K. Tolia · Siddhi M. Deshpande · Andrea R. McGowan · Amy Y. Zhao · Katherine L. Hughey · Alexander S. Rabin
Frontiers in Climate
doi 10.3389/fclim.2026.1930073
Review
Published
Analysis of the heterogeneity of the immune microenvironment of bone metastases and new strategies of nanotechnology intervention
Chenyang Wu · Xueli Qiu · Chao Wang · Jinyu Bai · Xiaozhong Zhou
Oncology Reviews
doi 10.3389/or.2026.1820639
Technology and Code
Published
The Desired Sensation Level bone conduction device prescriptive formula: new adaptations and applications for skin-driven bone conduction fittings
Susan Scollie · Steve Beaulac · Krystal Beh · Matthew Holden · Marlene Bagatto · Shilpi Banerjee · William (Bill) Hodgetts
Frontiers in Audiology and Otology
doi 10.3389/fauot.2026.1846344
Original Research
Published
The burden among caregivers who are caring for patients with dementia admitted under private nursing services
Asmahan A. M. Abdo · Erilyn Leigh C. Manalo · Liela Santander · Janice Samaco · Myra Aler · Moby Benny · Deborah Okemmuo · Maria Katrina Bacal · Samah Swedan · Kalpana Singh
Frontiers in Dementia
doi 10.3389/frdem.2026.1873575