Articles

Showing 178 articles

• Review

  Published 28 September 2026

  Phytocannabinoid-drug interactions: pharmacokinetic and pharmacodynamic mechanisms, clinical relevance and toxicological considerations

  Diogo Alexandre Gomes · Wellyngton Vieira Eufrázio · Marcella Silva Ribeiro · Linério Ribeiro de Novais Júnior · Flávia Rigo · Patrícia de Aguiar Amaral · Antonella Campanale · Antônio Inserra · Rafael Mariano de Bitencourt

  Frontiers in Toxicology

  doi 10.3389/ftox.2026.1952599

• Review

  Published 28 September 2026

  Multipath interaction network of annexin A2: multifaceted regulation and translational perspectives in neurological diseases

  Yong Guan · Ping Gu · Dachuang Guo · Liqiang Huang · Dongye Lian · Caicai Zhang · Jigao Feng · Hao Peng

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1916220

• Review

  Published 24 September 2026

  Black boxes and petri dishes: AI models for antimicrobial pharmacokinetics, drug properties, and resistance

  Jacob K. McPherson · Surbhi Sharma · Biswajit Mishra · Fadi Shehadeh · Eleftherios Mylonakis

  Frontiers in Bacteriology

  doi 10.3389/fbrio.2026.1926678

• Original Research

  Published 24 September 2026

  Integrated electrophysiological and payload-release assessment of neuronal responses to antibody-drug conjugates in human iPSC-derived sensory neurons: implications for in vitro neurotoxicity evaluation

  Taeko Kuroda · Xiaobo Han · Toshiki Mochizuki · Yuto Ishibashi · Aya Goto · Yuki Seki · Norimasa Miyamoto · Takashi Yoshinaga · Shoji Asakura · Ikuro Suzuki

  Frontiers in Toxicology

  doi 10.3389/ftox.2026.1855330

• Original Research

  Published 23 September 2026

  Perceived social support and life engagement among older adults using thermal health tourism services: the moderating role of aging anxiety

  Kadriye Sönmez

  Frontiers in Health Services

  doi 10.3389/frhs.2026.1901204

• Original Research

  Published 23 September 2026

  Associations between pre-to-post TMS-evoked potential changes and motor sequence learning across retention intervals

  Fransina Christina King · Narayanankutty Naduvilidam · Milos R. Ljubisavljevic · Fatima Yousif Ismail

  Frontiers in Human Neuroscience

  doi 10.3389/fnhum.2026.1925178

• Original Research

  Published 22 September 2026

  Economic evaluation of primary health care integration and targeted mass drug administration in counties in western Kenya

  Josphat Martin Muchangi · Wyckliff Omondi · Meshack Ndirangu · Carol Karutu · Irene Chami · Gilbert Wangalwa · Michael Ofire · Robert Ofwete · Kioko Kithuki · Nelly Saiti · Samuel Kamau · Lenson Kariuki · Paul Kibati · Japheth Athanasio · Geoffrey Njuhi · Yvonne Opanga · Emmanuel Musombi · Faith Mutegi · Dollycate N. Wanja · Festus Kipkorir · Hesbon Aoko · Chitiavi Juma

  Frontiers in Health Services

  doi 10.3389/frhs.2026.1858666

• Original Research

  Published 16 September 2026

  Plasma-activated water reprograms the root–rhizosphere continuum to enhance nitrogen use efficiency and sustain maize productivity under reduced nitrogen input

  Banoth Madhu · Nunavath Umilsingh · Jakku Prasanna · M. V. Priya · Surla Pradeepkumar

  Frontiers in Agronomy

  doi 10.3389/fagro.2026.1939374

• Original Research

  Published 16 September 2026

  Operationalising accessibility in marine pollution science communication: the Zeropol Hub case study

  Kathrin Kopke · Sonya Agnew · Thomas Heising · Lisa I. Devriese · Nina Vaupotič · Thomas Maes · Rian Ruhl · Sabine Pahl · Andy M. Booth · Thomais Vlachogianni

  Frontiers in Communication

  doi 10.3389/fcomm.2026.1913207

• Brief Research Report

  Published 15 September 2026

  Peripheral exosomal miRNAs as candidate molecular indicators associated with acupuncture at ST36 in an LPS-induced neuroinflammation model

  Seung-Nam Kim

  Frontiers in Molecular Neuroscience

  doi 10.3389/fnmol.2026.1917472

• Brief Research Report

  Published 15 September 2026

  R2Tg retrotransposon mediated targeted integration of exogenous genes into the 28S rDNA locus in mammalian cell lines for PKU gene therapy

  Xiuyuan Wang · Ziqi Wen · Rongjun Xu · Wenjing Shi · Yiling Long · Xingri Zhan · Rui Su · Jia Fei · Yumin Li

  Frontiers in Genome Editing

  doi 10.3389/fgeed.2026.1893815

• Original Research

  Published 14 September 2026

  Exploratory scaffold hopping strategies led to identification of novel histamine H 3 and H 4 receptor ligands

  Flávia B. Lopes · Denise Mönnich · Gustavo A. B. Fernandes · Steffen Pockes · João Paulo S. Fernandes

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1944403

• Review

  Published 14 September 2026

  Animal reuse in safety assessment studies: a review of current practices, challenges and 3Rs opportunities

  John S. Kendrick · David A. Shaw · Marie Jourdain · Claudia Senn · Helen Beyer · Fiona R. Sewell

  Frontiers in Toxicology

  doi 10.3389/ftox.2026.1854281

• Original Research

  Published 11 September 2026

  Pain profiles in pancreatic cancer and chronic pancreatitis: a multicenter cross-sectional analysis

  Marie-Theres Kassik · Mahya Faghih · Conrad Bandhauer · Josefine Jäger · Sophie Rauschenberg · Søren S. Olesen · Daniel A. Laheru · Lei Zheng · Anna E. Phillips · Dhiraj Yadav · Jonas Rosendahl · Vikesh K. Singh · Asbjørn M. Drewes · Marko Damm

  Frontiers in Pain Research

  doi 10.3389/fpain.2026.1903789

• Original Research

  Published 11 September 2026

  Median nerve electrical stimulation promotes myelin regeneration through regulating miR-1-3p/BDNF/TrkB-MAPK pathway in a transient cerebral ischemia rat model

  Rui Li · Jingyi Lu · Chengcai Zhang · Xiaowei Zhang · Meiqi Wang · Ping Zhang · Kunli Yang · Hongmei Fang · Ying Gao · Kistina Mohamed · Che Ismail Che Noh · Yi Li · Kai Ling Chin

  Frontiers in Behavioral Neuroscience

  doi 10.3389/fnbeh.2026.1820913

• Original Research

  Published 10 September 2026

  Palmitoylation-related lncRNAs link molecular signaling, immune remodeling, and tumor progression in glioma: prognostic modeling and functional validation of LYRM4-AS1

  Juan Xu · Chen Zhang · Lingling Pu · Xiaoyang Zhu · Xiaoan Sheng · Juanjuan Dong · Miaomiao Song · Chao Wang

  Frontiers in Molecular Neuroscience

  doi 10.3389/fnmol.2026.1901839

• Review

  Published 10 September 2026

  Semiochemical inhibitors for protecting conifers from bark beetles (Coleoptera: Curculionidae) in the Western United States: research, development, and application

  Christopher J. Fettig · Jackson P. Audley

  Frontiers in Insect Science

  doi 10.3389/finsc.2026.1939049

• Original Research

  Published 9 September 2026

  A novel assessment of self-perceptions of recovery from illness and injury in U.S. Navy service members

  Lisa M. Hernández · Nikita R. Tovey · Anu Venkatesh · Kristin J. Heaton · Justin S. Campbell · Jessica M. Hru · Marcus K. Taylor

  Frontiers in Rehabilitation Sciences

  doi 10.3389/fresc.2026.1846239

• Systematic Review

  Published 8 September 2026

  Trends and mechanistic insights into hypertension-associated hearing loss: a 20-year perspective (2005–2025)

  Jianlong Xiong · Tao Xu · Huan Wu · Liubo Xiang · Zhihao Zhao · Yuanpeng Deng · Wansheng Wang

  Frontiers in Molecular Neuroscience

  doi 10.3389/fnmol.2026.1864657

• Original Research

  Published 7 September 2026

  Revealing RELL1 signaling relying on the phosphoregulatory network analysis

  Pathiyil Sajini Sekhar · Diya Sanjeev · Amal Fahma · Suhail Subair · Athira Perunally Gopalakrishnan · Prathik Basthikoppa Shivamurthy · Rajesh Raju · Sowmya Soman

  Frontiers in Bioinformatics

  doi 10.3389/fbinf.2026.1939325

• Original Research

  Published 4 September 2026

  Computational insights into synergistic mechanisms of PD-901 and 5-azacitidine targeting PTPN11 (SHP2) E76K mutation in juvenile myelomonocytic leukemia

  Abeer M. Al-Subaie · Balu Kamaraj

  Frontiers in Bioinformatics

  doi 10.3389/fbinf.2026.1887328

• Systematic Review

  Published 4 September 2026

  Organ-specific apoptotic pathways induced by micro- and nanoplastics: a systematic review of in vitro toxicological evidence

  Laura Maria Messina · Maria Concetta Scuto · Gabriella Lupo · Cinzia Maria Grazia Lombardo · Caterina Ledda · Angela Trovato Salinaro

  Frontiers in Toxicology

  doi 10.3389/ftox.2026.1908508

• Original Research

  Published 4 September 2026

  Comparative in vitro safety assessments of synthetized and plant-derived cannabidiol (CBD), and pharmacokinetics of synthetized CBD: evidence of similar toxicological profiles and accumulation upon repeated oral administration

  E. T. Wong · D. Bovard · W. K. Schlage · W. Xia · H. Isa · O. Sirbu · A. R. Kolli · G. N. Nikolajsen · S. S. Jensen · J. Ho · B. Phillips · J. Hoeng

  Frontiers in Toxicology

  doi 10.3389/ftox.2026.1844643

• Review

  Published 2 September 2026

  Beyond tobacco: understanding the growing burden of lung adenocarcinoma in women

  Michael Christian A. Virata · Rizal Michael Ramos Abello · Edroico Mari Beltran Brillante · Jasmine Soco Interior · Patrick Reyes Relacion · Ryan Gabriel C. Molen · Eryll Paolo M. Alea · John Cedric P. Mojica

  Oncology Reviews

  doi 10.3389/or.2026.1813124

• Review

  Published 1 September 2026

  Ultrasound-assisted multiscale structural engineering of plant proteins: mechanisms and structure–property relationships

  Gulcin Yildiz · Gökçen Yıldız

  Frontiers in Soft Matter

  doi 10.3389/frsfm.2026.1893101

• Original Research

  Published 28 August 2026

  Prioritizing earthquake-prone countries for implementing the operational guidance on infant and young child feeding in emergencies (OG-IFE): a descriptive risk mapping and prioritization analysis

  Aly Drame · Andrés Abarca · Jodine Chase · Mija Ververs

  Frontiers in Disaster and Emergency Medicine

  doi 10.3389/femer.2026.1830252

• Original Research

  Published 28 August 2026

  Evolution of health system resources and factors associated with the quality of care for epidemic-prone diseases in Guinea: a national cross-sectional study

  Dimaï Ouo Kpamy · Fatoumata Cherif · Sory Conde · Fodé Amara Traore · Sidikiba Sidibe · Bassirou Diarra · Peter John Winch · Abdoulaye Toure · Sakoba Keita · Seydou Doumbia · Alexandre Delamou

  Frontiers in Epidemiology

  doi 10.3389/fepid.2026.1818264

• Original Research

  Published 21 August 2026

  Identifying and resolving ethical challenges related to the enrollment of black individuals with chronic kidney disease in U.S. health registries and clinical research: a qualitative study

  Henry Asante Antwi · Adaeze Aroh · Deidra Crews · Rodney Elliot · Nicole Huillca · C. Daniel Mullins · Mehar Sandhu · Abdou Simon Senghor

  Frontiers in Epidemiology

  doi 10.3389/fepid.2026.1753620

• Original Research

  Published 21 August 2026

  Breastmilk transfer and infant exposure to atazanavir/ritonavir in breastfeeding women with HIV: results from IMPAACT 2026

  Emily Anne Barr · Mauricio Pinilla · Jeremiah D. Momper · Ahizechukwu C. Eke · Lucy Koech · Kristina M. Brooks · Victoria Ndyanabangi · Sandra K. Burchett · Sujith Valiyaparambil · Mark Mirochnick · Alice Marie Stek · Brookie M. Best · Rachael Jeffrey · Chelsea Stotz · Marije Van Schalkwyk · Renee Browning · David E. Shapiro · Kathleen M. Powis

  Frontiers in Reproductive Health

  doi 10.3389/frph.2026.1892081

• Review

  Published 20 August 2026

  From metabolism to neurodegeneration: how microglial functional reprogramming drives neurodegenerative diseases

  Qiaoqiao Cui · Ke Zheng · Qiyun Liu · Lizhen Wang · Yixin Liu · Ruifang Bai · Wei Zhang · Junhong Guo · Xueli Chang · Juan Wang

  Frontiers in Molecular Neuroscience

  doi 10.3389/fnmol.2026.1921079

• Original Research

  Published 20 August 2026

  Effects of biofertilizers under varying irrigation regimes on soybean productivity and soil fertility in arid agroecosystems

  Ulugbek Nematov · Subhana Shahmaliyeva · Bakhtiyar Matyakubov · Khayrullo Tursunov · Dilorom Yormatova · Anvarjon Karabayev · Zokir Tajiyev · Makhbuba Khayitova · Nodirbek Mirfozilov · Dilfuzaxon Karimova · Madinaxon Turdiyeva · Buta Xushvaktov · Oybek Normuratov · Shohruh Ahmadov · Jamilakhon Ermakova · Ifoda Akhmedkhodjaeva · Botir Khaitov

  Frontiers in Soil Science

  doi 10.3389/fsoil.2026.1895897

• Review

  Published 20 August 2026

  Microglia-mediated neuroinflammation in Alzheimer’s disease: mechanisms and emerging therapeutic targets

  Lianjing Xu · Ying Zhang · Li Jiang · Jin Feng Xing · Jing Hu · Tianye Lan · Guang Ta

  Frontiers in Cellular Neuroscience

  doi 10.3389/fncel.2026.1902577

• Review

  Published 18 August 2026

  The ERK MAPK pathway in mesenchymal glioblastoma: tumorigenesis, microenvironmental reprogramming, and the therapeutic promise of RAS(ON) multi-selective inhibition

  Uma M. Basole · Mary M. Fitzpatric · Joseph Donohoe · Shashank Obulasetti · William Snider · Emily Haugen · Damir Garcia · Ana Gonzalez-Manteiga · Mathieu Sertorio · Marc Oria

  Frontiers in Molecular Neuroscience

  doi 10.3389/fnmol.2026.1857885

• Review

  Published 18 August 2026

  Electromagnetic neuromodulation for chronic pain: historical context, contemporary modalities, and evidence gaps

  Laura Dipietro · Ciro Ramos-Estebanez · Paola Gonzalez-Mego · Anna Carolyna Gianlorenco · Arisara Wongtanawat · Christopher Robinson · Salim M. Hayek · Felipe Fregni · Timothy Wagner

  Frontiers in Pain Research

  doi 10.3389/fpain.2026.1901466

• Original Research

  Published 11 August 2026

  Development and evaluation of biochar formulated fertilizers for climate-smart sustainable crop production

  Alemayehu K. Shembo · Addisie Geremew · De’Zarae M. Guthrie · Kerrington N. Thompson · Emmanuel O. Ali · Selamawit Woldesenbet · Olukayode Kuloyo · Christian Davies · Ram L. Ray · Laura Carson

  Frontiers in Soil Science

  doi 10.3389/fsoil.2026.1880824

• Original Research

  Published 7 August 2026

  Wildfire contributions to prenatal PM 2.5 exposure in the contiguous United States, 2003–2019

  Menglu Liang · Amir Sapkota · Hao He · Samyam Aryal · Nicole E. Sieck · Michel Boudreaux

  Frontiers in Environmental Health

  doi 10.3389/fenvh.2026.1838836

• Original Research

  Published 7 August 2026

  Functional phosphoproteomic analysis of SMG1 in nonsense-mediated mRNA decay and DNA damage repair in cancer

  Apoorva K. A. Pai · Leona Dcunha · Athira Perunelly Gopalakrishnan · Samseera Ummar · Athira C. Rajeev · Rajesh Raju

  Frontiers in Systems Biology

  doi 10.3389/fsysb.2026.1788470

• Review

  Published 6 August 2026

  Secreted proteins of Mycobacterium tuberculosis as therapeutic targets for drug discovery

  Anthony Musaazi Kaweesa · Divya Tiwari

  Frontiers in Tuberculosis

  doi 10.3389/ftubr.2026.1736139

• Original Research

  Published 5 August 2026

  Characterization of micro- and nanoplastics in human placental tissue by pyrolysis gas chromatographic ion mobility mass spectrometry

  Nikita E. Harvey · Justine R. Bissonnette · Stacy Lambe · T. Nadine Burry · John G. Sled · John C. Kingdom · Ahmet A. Baschat · André J. Simpson · Lindsay S. Cahill · Karl J. Jobst

  Frontiers in Analytical Science

  doi 10.3389/frans.2026.1881804

• Original Research

  Published 5 August 2026

  Women as agents of change in community-based waste management: a thematic analysis

  Hilmiana · Imas Soemaryani · Rina Novianty Ariawaty · Kurniawan Saefullah · Devi Alviani · Tri Febrianti · Dara Sagita Triski

  Frontiers in Human Dynamics

  doi 10.3389/fhumd.2026.1852099

• Brief Research Report

  Published 4 August 2026

  Immunoglobulin replacement therapy in antineutrophil cytoplasmic antibody-associated vasculitis with rituximab-associated hypogammaglobulinemia: infection outcomes and disease course in a retrospective cohort

  Matthew Gross · Aditi Singh · Raj Roshan · Antoine Azar · Duvuru Geetha

  Frontiers in Nephrology

  doi 10.3389/fneph.2026.1861999

• Review

  Published 3 August 2026

  The human health and well-being benefits of birds: a systematic scoping review of interaction patterns

  Matthew H. E. M. Browning · Olivia McAnirlin · William Miller · Hunter Beard · Matthew W. Breed · Sofia Elena Rubalcava · Charlie Engelman · Nazanin Hatami · Anisha Jaggi · Allison Maynard · Holly Merker · Saeedeh Morassafar · Kathy L. Siepker · Seunguk Shin · Marianne Vinas-Rogers · Kuiran Zhang · Landon Pollack

  Frontiers in Bird Science

  doi 10.3389/fbirs.2026.1871909

• Case Report

  Published 3 August 2026

  Case Report: Recurrent hypoglycemia due to graft-derived insulinoma in a patient with type 1 diabetes following pancreas-kidney transplantation

  Carme Figueredo · Maria Iraola · Marta Aymerich · Neus Villamor · Ivan Archilla · Joana Ferrer-Fàbrega · Antonio J. Amor · Pedro Ventura-Aguiar

  Frontiers in Transplantation

  doi 10.3389/frtra.2026.1889705

• Review

  Published 31 July 2026

  Phosphorylation dynamics of sodium-independent organic anion transporter SLCO4A1 and its role in diseases: a review

  Jaytha Thomas · Suhail Subair · Althaf Mahin · Athira Perunelly Gopalakrishnan · Prathik Basthikoppa Shivamurthy · Athira C. Rajeev · Rajesh Raju

  Frontiers in Systems Biology

  doi 10.3389/fsysb.2026.1780024

• Perspective

  Published 28 July 2026

  Redefining the geography of pharmaceutical innovation: Kelly Chibale as a harbinger for integrated drug discovery in Africa

  Fidele Ntie-Kang · Peter Mubanga Cheuka · Richard Kwamla Amewu · Elizabeth V. M. Kigondu · Collen Masimirembwa

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1884834

• Case Report

  Published 28 July 2026

  Case Report: Non-invasive [ 89 Zr]Zr-DFO-trastuzumab positron emission tomography in the multimodal characterisation of platinum-resistant high-grade serous ovarian cancer

  Joana do Mar Ferreira Machado · Robert Winzer · Rudi Apolle · Almuth Forberger · Kristof Zarschler · Torsten Knieß · Martin Kreller · Klaus Kopka · Oliver C. Kiß · Jan Dominik Kuhlmann · Pauline Wimberger · Matthias Miederer · Theresa Link

  Frontiers in Nuclear Medicine

  doi 10.3389/fnume.2026.1832138

• Mini Review

  Published 28 July 2026

  Trehalose metabolism: an integrative hub linking energy homeostasis and development in insects

  Sharada D. Mohite · Rakesh S. Joshi

  Frontiers in Insect Science

  doi 10.3389/finsc.2026.1872741

• Case Report

  Published 24 July 2026

  Congenital hepatic fibrosis in an adult female combined with Von Meyenburg complex and autosomal dominant polycystic kidney disease: a case report

  Xinrui Ren · Yu Cui · Jiayi Song · Yiwen Tang · Xiaoying Xie · Wanchun Zhu · Zhuo Yu · Lingying Huang · Yueqiu Gao

  Frontiers in Gastroenterology

  doi 10.3389/fgstr.2026.1876545