Original Research
Published
Proteomic analysis of bioprinted pancreatic tumor models under different nutrient conditions
Busra Buyuk · Ming Li · Xueer Song · Kaiming Ye
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1921652
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Showing 307 articles
Perspective
Published
Hydrogen gas and olfactory dysfunction in Alzheimer’s disease: the Hydrogen–Olfactory–Limbic hypothesis
Ligao Bao · Dunfu Eer
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1937419
Original Research
Published
tRNA regulatory ecosystem states shape tissue and circulating small-RNA landscapes in gastric cancer
Jie Liu · Yangyang Chen · Jiaqing Hu · Xujin Wei · Xiaoling Zheng
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1960697
Original Research
Published
Exploring the immune enhancement effect of radiotherapy combined with NK cells on non-small cell lung cancer based on proteomics technology
Cui Chang · Tang Youming · Lu Ying · Lei Ningning · Guo Chunhui · Wei Dekai · Liang Mei · Wu Qiyuan · Liu Gechen · Wu Fasheng · Chen Jibing
Oncology Reviews
doi 10.3389/or.2026.1853377
Review
Published
Artificially intelligent modeling of macromolecular assemblies
Margherita Bini · Valentina Tozzini
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1856649
Review
Published
Exosomal microRNAs as biomarkers of multimorbidity risk in lean and obese women with polycystic ovary syndrome
Debarati Halder · P. V. Varshini · Tridip Mitra · A. H. Sruthi Anil Kumar · Piyush Agrawal · Mrinmoy Das · A. Senthil Kumar · R. Sajeetha Kumari · S. N. Meenakshi Sundari · Rajiv Janardhanan
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1868855
Original Research
Published
Mechanistic study on components of Angelica Pubescens-Taxillus Chinensis in improving compression-induced intervertebral disc degeneration via piezo1/NF-κB signaling axis
Fei Yang · Chaoqun Feng · Guangye Li · Junwen Deng · Yunchuan Gou · Bingyi Yang · Ying Zhang · Xin Zhou · Chuan Leng · Maoyin Luo · Rigao Chen · Xiaohong Fan
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1935597
Original Research
Published
Dynamic phosphorylation of DGCR8 regulates embryonic stem cell differentiation and microprocessor function
Ka Weng Leong · Lawrence Mok · Karen Gu · Jonathan S. Oakhill · Mark M. W. Chong
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1918038
Review
Published
Cellular remodeling of lipedema affected subcutaneous adipose tissue
Sabrina Gohlke · Francisco Garcia-Carrizo · Robin Upmeyer · Tim J. Schulz
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1893552
Original Research
Published
3-O-ethyl-L-ascorbic acid modulates pro-inflammatory cytokine and extracellular matrix-related biomarker levels in human lung fibroblasts: an in vitro study
Ali Türkan · Murat Türkoğlu · Gülistan Öncü · Hakan Sevinç
Acta Biochimica Polonica
doi 10.3389/abp.2026.16774
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Original Research
Published
Selective autophagy inhibition alleviates oxidative stress-associated neurodegeneration in an AD+CCH model
Xiaorui Huang · Jufang Chen · Zhicheng Lu · Jie Wang · Xuelian Luo · Qiuyan Qin · Qin Yang · Chongdong Jian · Xuebin Li · Jingwei Shang
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1870441
Review
Published
MSC-derived extracellular vesicles for spinal cord injury: inflammatory microenvironment modulation, stage-dependent repair mechanisms, and translational challenges
Hang Yu · Yifan Liu · Shulong Yin · Haoyue Hu · Linquan Li · Taotao Zhu · Jie Liu · Sheng Liu · Chenxi Zhao · Shiqing Feng
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1960271
Review
Published
Emerging NPR-B agonists for cartilage and bone: from CNP biology to translational compound design
Yasuhiko Ago · Amali Karunathilaka · Jacky M. Guerrero-Vargas · Shunji Tomatsu
Frontiers in Chemistry
doi 10.3389/fchem.2026.1949456
Mini Review
Published
Electrochemical scanning tunneling microscopy as a tool for probing protein function: from electron transfer to molecular recognition and chemosensation
Josep Samitier · Anna Lagunas
Frontiers in Biophysics
doi 10.3389/frbis.2026.1945182
Perspective
Published
Orexins and neuregulins as exemplars of peptide physiology in the brain: experimental challenges and implications for neuropathology
Laura Clara Grandi · Marta Cerina · Alida Amadeo · Andrea Becchetti
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1933123
Review
Published
Understanding the strengths and limitations of recombinant protein studies
Daniele Dell’Orco · Karl-Wilhelm Koch
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1927411
Review
Published
Telomeric autophagy in human health, aging, and diseases
Xingyao Li · Xili Wu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1922188
Review
Published
Sustainable soft materials for food packaging: quality preservation and environmental impact
Sweta Joshi · Mantasha Hasan · Dhananjay Sharma · Mayuri Rastogi · Bushra Shaida · Swati Kimothi
Frontiers in Soft Matter
doi 10.3389/frsfm.2026.1898833
Original Research
Published
The ALLPreT panel of legume allergen preparations: characterization of optimized protein extracts for allergen composition, IgE-binding and IgE-crosslinking properties
Ana Laura Olivares-Martínez · Sim Ray Yue · Stefanie Randow · Marie Vestergaard Lukassen · Isabela Assugeni · Maria Oliver · Annette Kuehn · Kitty Verhoeckx · Katrine Lindholm Bøgh · Thomas Holzhauser
Frontiers in Allergy
doi 10.3389/falgy.2026.1938923
Original Research
Published
Consumer acceptance and stated willingness to pay a premium for plant- and insect-based foods in Greece: evidence from a younger-skewed sample
Konstantina Panagiotakopoulou · Panagiotis Zoumboulakis · Christos Theofrastos Fois
Frontiers in Sustainability
doi 10.3389/frsus.2026.1886541
Original Research
Published
Quantitative analysis of proteostasis disruption following siRNA-mediated HSP70 depletion in HeLa cells
Hatice Esenkaya
Frontiers in Genetics
doi 10.3389/fgene.2026.1856671
Original Research
Published
Virtual screening of phytochemicals against multiple protein targets of Alzheimer’s disease
Samuel Mesfin · Naamah Bloch · Abraham O. Samson
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1922953
Mini Review
Published
From dynamic condensates to pathological assemblies: the phase behavior of tau and α -synuclein
Suelen Camargo · Kevin Novelo · Scott D. Ryan
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1965177
Original Research
Published
Reverse vaccinology and immunoinformatics-driven design of a multiepitope vaccine candidate against Renibacterium salmoninarum
Cristóbal Morales · Vicente Arriagada · Erick Bonilla · Bruno Prina · Esteban Godoy · Benjamín Molina-Chávez · Alberto Osorio · Emilio Gutierrez · Victor Roa · Leonardo A. Gómez · Ángel A. Oñate
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1899416
Original Research
Published
Integrated computational investigation of Glycosmis pentaphylla -derived compounds against major venom proteins of Daboia russelii
Sana S. Hussain · Danie J. Kingsley
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1906533
Review
Published
Decellularized dental pulp extracellular matrix for pulp-dentin regeneration: a narrative review of processing, bioactivity, delivery, preclinical evidence, and translational challenges
Xinli Zhang · Mengjie Dong
Frontiers in Dental Medicine
doi 10.3389/fdmed.2026.1962311
Original Research
Published
Subcellular mapping of ToBRFV movement protein in Nicotiana glutinosa via confocal laser scanning microscopy and agroinfiltration
Ritika Dwivedi · Tanu Vishwakarma · Archana Rathore · Dilip Kumar Maurya · Prabhat Kumar Maurya · Vijayanandraj Selvaraj · Praveen Chandra Verma · Susheel Kumar
Frontiers in Virology
doi 10.3389/fviro.2026.1870416
Review
Published
Paraprobiotics and postbiotics: from mechanistic evidence to food applications and clinical translation
Diana Pasarin · Iuliu-Gabriel Malos · Andra-Ionela Ghizdareanu · Antonia Gabriela Malos · Daniela Ianitchi · Gabriela Malos · Noemi Elena Virna · Catalin Bogdan Matei · Alina Alexandra Dobre · Luiza Capra · Georgeta Ramona Ivan · Bogdan Frunzareanu
Frontiers in Food Science and Technology
doi 10.3389/frfst.2026.1965558
Original Research
Published
Systemic responses to intravenous rAAV administration in boys with Duchenne muscular dystrophy
Brooke E. Harris · Brooke M. Seldin · Sam C. Towne · Orinda R. Hobson · Eli Zerpa · Victor Prima · H. Lee Sweeney · David W. Hammers
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2026.1953867
Original Research
Published
Immunoinformatics-guided design and in silico evaluation of BAFF- and APRIL-adjuvanted multi-epitope vaccine candidates against human metapneumovirus
Reham M. Alahmadi · Maaweya Awadalla · Halah Z. Al-Rawi · Ayman Mubarak · Wafa Ali Eltayb · Mohnad Abdalla · Han Yu · Bandar Alosaimi
Frontiers in Virology
doi 10.3389/fviro.2026.1949694
Original Research
Published
Immunoinformatics-based design of a multi-epitope mRNA vaccine candidate targeting the major human-infecting hepatitis E virus genotypes 1–4
Maham Mehrangaze Khonza · Zain Saeed · Zohra Jabeen · Wafaa Arab · Sehrish Kakakhel · Maham Yamin · Mazen M. Ghaith · Aneela Javed · Ali Zohaib · Rwaa H. Abdulal
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1922523
Review
Published
Genetic determinants of tendon and ligament injuries in athletes: a narrative review from single variants to gene-gene interactions
Amina Marrouh · Arij El Haddouchi · Souad Kartti · Elmostafa El Fahime · Saber Boutayeb · Younes Chagar · Christophe Baudot · Lahcen Belyamani · Taoufiq Dakka · Rachid Eljaoudi
Frontiers in Systems Biology
doi 10.3389/fsysb.2026.1858521
Original Research
Published
The optimized endolysosomal degradation assay with standardized enzyme activity represents an orthogonal method for predicting protein immunogenicity and T cell epitopes
Elif Öztemiz · Christof Regl · Hans Brandstetter · Christian G. Huber · Kitty Verhoeckx · Gabriele Gadermaier
Frontiers in Allergy
doi 10.3389/falgy.2026.1936335
Original Research
Published
Combined RNA- and DNA-targeting CRISPR ribonucleoproteins enhance suppression of HBV transcripts
Puja Banik · Addison C. Hill · Madison B. Schank · Yi Zhang · Juan Zhao · Jaeden S. Pyburn · Holly Orfield · Yuezu Wu · Mohammad J. Hajipour · Mohamed El Gazzar · Shunbin Ning · Jonathan P. Moorman · Zhi Q. Yao · Ling Wang
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1824895
Review
Published
Blood-based proteomics for schizophrenia: candidate biomarkers for risk assessment and precision psychiatry
Alexey S. Kononikhin · Anna E. Bugrova · Arina S. Foliforova · Maria I. Indeykina · Polina A. Strelnikova · Natalia V. Zakharova · Anna Y. Morozova · George P. Kostyuk · Evgeny N. Nikolaev
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1882675
Review
Published
Multifunctional biohybrid systems of plant-derived nanovesicles with inorganic nanomaterials
Ningtao Yuan · Tao Meng · Hong Bi
Frontiers in Materials
doi 10.3389/fmats.2026.1967278
Review
Published
Lysosomes as chemical and metabolic organizers of central nervous system injury and repair
Tengfei Zhao · Hanxu Huang · Yifan Wang · Yuliang Zhong · Zhiwei Zhong · Deting Xue · Wei Zhu · Kan Xu
Frontiers in Chemistry
doi 10.3389/fchem.2026.1891677
Original Research
Published
Enzyme-mediated site-specific functionalization of mRNA-containing TMV nanorods produced in yeast
Jerrell Tisnado · Ana Luisa Duran Meza · David Silverio Moreno Gutierrez · Nina M. Harpell · Alyssa Cruz · Charles M. Knobler · William M. Gelbart
Frontiers in Virology
doi 10.3389/fviro.2026.1955107
Review
Published
Engineering TnpB as a compact RNA-guided genome editor from molecular constraints to design principles
Bin Ma · Yimiao Li · Dongsheng Zhang · Yu Wu · Jie Gao · He Li · Shuang Jia
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1945303
Original Research
Published
Genome edited sheep generated by zygote electroporation of prime editor ribonucleoproteins
Zhixuan Yu · Junjin Li · Menghao Liu · Qi Qi · Zengyi Duan · Ziyu Yang · Boyuan Guan · Jiawang Chen · Jian Hou
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1931608
Original Research
Published
Multi-omics analysis unveils inflammatory and metabolic alterations between the synovium and cartilage in patients with knee osteoarthritis
Wenlong Xu · Shao Cheng · Zhen Wang · Shang Ma · Xiaokun Dong · Jinxin Ma · Bowen Zheng · Bingqi Wei · Shangzeng Wang
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1855139
Original Research
Published
Evaluation of the phytochemical profile, biological activities, and acute toxicity of Cistus ladanifer aerial part extracts: experimental and in silico investigations
Fatima Zahra Ayyad · Mouad Lahyaoui · Hajar Lahyaoui · Morad Kaddouri · Mohamed El Yaqoubi · Mouhcine Hayani · Amina Bari · Ahde El Imache · Joe Miantezila Basilua · Abdelaaty A. Shahat · Mohammed S. Alharbi · Touriya Zair
Frontiers in Chemistry
doi 10.3389/fchem.2026.1911960
Original Research
Published
DHA-dominant Omega-3 compositions enhance PSD-95 organization and glutamatergic protein expression
Gerardo Medina · Stephen D. Baird · Lilia A. Rodriguez-Alcocer · Alex E. MacKenzie
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2026.1947075
Review
Published
Expression and role of HSPA5 in environmental toxin-induced neurological disorders
Yurong Wang · Yang Lv · Ruidong Zhao · Xin Guo · Jing Gao · Tong Wang · Dongmei Yao · Xin Li · Bingchun Liu · Jianlong Yuan
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1964213
Original Research
Published
A novel minimally humanized mouse model of aniridia for preclinical evaluation of CRISPR gene editing strategies
Seyedeh Zeinab Mirjalili Mohanna · Andrea J. Korecki · Pardis Kazemian · Tess C. Lengyell · Bethany A. Adair · Blair R. Leavitt · Elizabeth M. Simpson
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1910209
Review
Published
Breaching the Weismann barrier – a role of vitellogenin yolk proteins in nematode non-Mendelian inheritance
Shiela Pearl Quiobe · Ralf J. Sommer
Frontiers in Ecology and Evolution
doi 10.3389/fevo.2026.1956995
Review
Published
Circular RNAs: from transcriptional noise to engineered therapeutics
Aaron C. Chack · Chad V. Pecot
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1894220
Original Research
Published
A novel approach to HPV16 VLP construction and production with improved accessibility and particle sorting potential
Morgan Williamson · Caleb Boren · Rahul Kumar · Lauren Gollahon
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2026.1941186