Review
Published
Neu5Gc and beyond: sialylation at the innate immune and thromboinflammatory interface of xenotransplantation
Jae Young Kim
Frontiers in Transplantation
doi 10.3389/frtra.2026.1968710
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Articles
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Showing 328 articles
Original Research
Published
Integrative bioinformatics screening of a M2 macrophage-associated gene signature for osimertinib resistance
Yajie Huang · Yaozhong Zhang · Jian Shi
Frontiers in Genetics
doi 10.3389/fgene.2026.1928986
Review
Published
Multipath interaction network of annexin A2: multifaceted regulation and translational perspectives in neurological diseases
Yong Guan · Ping Gu · Dachuang Guo · Liqiang Huang · Dongye Lian · Caicai Zhang · Jigao Feng · Hao Peng
Frontiers in Genetics
doi 10.3389/fgene.2026.1916220
Review
Published
CLDN18 and FGFR2 splicing variants are emerging tumor-associated antigens for cancer therapy
Masuko Katoh · Masaru Katoh
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2026.1927389
Specialty Grand Challenge
Published
The grand challenge in cellular neurophysiology
Björn Kampa · Arianna Maffei
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1980835
Original Research
Published
Integrative multi-omics characterization of KLRB1/CD161 in diffuse large B-cell lymphoma: associations with immune context, subtype biology, and therapeutic response
Erwei Li · Yingying Tang · Yuanyuan Wanyan · Yu Liang
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1903725
Original Research
Published
TrkC-dependent regulation of dendritic branching shapes dendritic bundle architecture in the rat granular retrosplenial cortex
Toshio Miyashita
Frontiers in Neural Circuits
doi 10.3389/fncir.2026.1925955
Perspective
Published
Bioaminergic signaling in parasitic flatworms: a perspective for linking GPCRs to behavior and drug discovery
Erika Bistran · M. Evelyn Carpenter · Daniel J. Sprague
Frontiers in Parasitology
doi 10.3389/fpara.2026.1933406
Original Research
Published
Quadrimodal in vivo assay for detection of adverse neuro-behavioral effects: validation using dextromethorphan
Günther K. H. Zupanc · Abigail L. Zodl · Naya M. Sabha
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1917655
Original Research
Published
Immunoinformatics-guided design and in silico evaluation of BAFF- and APRIL-adjuvanted multi-epitope vaccine candidates against human metapneumovirus
Reham M. Alahmadi · Maaweya Awadalla · Halah Z. Al-Rawi · Ayman Mubarak · Wafa Ali Eltayb · Mohnad Abdalla · Han Yu · Bandar Alosaimi
Frontiers in Virology
doi 10.3389/fviro.2026.1949694
Original Research
Published
Immunoinformatics-based design of a multi-epitope mRNA vaccine candidate targeting the major human-infecting hepatitis E virus genotypes 1–4
Maham Mehrangaze Khonza · Zain Saeed · Zohra Jabeen · Wafaa Arab · Sehrish Kakakhel · Maham Yamin · Mazen M. Ghaith · Aneela Javed · Ali Zohaib · Rwaa H. Abdulal
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1922523
Review
Published
Therapeutic reprogramming of natural killer cells for solid tumors: expanding frontiers into rare and ultra-rare malignancies
Francesca Rosato · James W. Hodge
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1955532
Review
Published
Purinergic signaling in the gut neuro-glial-immune axis: mechanisms of homeostasis, inflammation, and gastrointestinal dysfunction
Eduardo E. Valdez-Morales · Andrómeda Liñán-Rico · Raquel Guerrero-Alba
Frontiers in Gastroenterology
doi 10.3389/fgstr.2026.1954794
Review
Published
Molecular systems of emerging viruses: replication, host immune evasion, cross-species adaptation and precision countermeasures
Abdul Bari Hejran · Parwiz Niazi · Mohammad Yaqoub Sangin
Frontiers in Virology
doi 10.3389/fviro.2026.1926007
Review
Published
GPCR signaling systems facilitate precision interventions for multi-oncology therapy
Ashley Del Pozo · Mia Pardo · Tabitha Boeringer · Carter J. Craig · Ramzia Sorathia · Madeline Millican · Stuart Maudsley
Frontiers in Systems Biology
doi 10.3389/fsysb.2026.1940022
Original Research
Published
Integrated microarray-based and single-cell transcriptomic analyses reveal cell adhesion-related fibrotic remodeling signatures in heart failure
Shun Zhang · Le Li · Zuohua Li · Xiaojun Wang · Juan Zhou · Qing Lyu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1929610
Original Research
Published
DHA-dominant Omega-3 compositions enhance PSD-95 organization and glutamatergic protein expression
Gerardo Medina · Stephen D. Baird · Lilia A. Rodriguez-Alcocer · Alex E. MacKenzie
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2026.1947075
Original Research
Published
The aryl hydrocarbon receptor is expressed in non-sensory cells in the cochlea and regulates hair cell survival
Sujata Pandey · Brandon C. Cox
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1943479
Original Research
Published
Unraveling skeletal muscle senescence in an in vitro cell culture model
Kayo Moreira Bagri · Morgana Teixeira Lima Castelo-Branco · Claudia Mermelstein
Frontiers in Aging
doi 10.3389/fragi.2026.1866906
Review
Published
Novel bioactive compounds in the treatment of osteoporosis: chemistry-driven discovery from preclinical validation to clinical translation
Honghui Fan · Songtao Jin
Frontiers in Chemistry
doi 10.3389/fchem.2026.1917991
Original Research
Published
The role of challenging exercise in improving behavioral dysfunction in a mouse model of Parkinson’s disease
Yuan Zeng · Ping Chen · Quan Yang · Bing Liu · Liuting Huang · Kai Zhang · Shumin Liu
Frontiers in Behavioral Neuroscience
doi 10.3389/fnbeh.2026.1887753
Original Research
Published
Adoptive T Cell therapy for cancer and autoimmune disease: current advances, challenges, and future directions
Qiu-Hong Bao · Angel Wu · Jianming Pang · Junwei Wang · Qingqing Chen · SuWen Wu
Oncology Reviews
doi 10.3389/or.2026.1905358
Original Research
Published
Sex-associated circadian signaling signatures in the lateral hypothalamus
Sara K. Pintwala · Patrick M. Fuller
Frontiers in Sleep
doi 10.3389/frsle.2026.1895831
Review
Published
Brain endothelial homeostasis in psychiatric disorders: mechanisms, evidence, and translational opportunities
Mengjie Zhang · Xueying Huang · Lin Yao · Wenqing Wu
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1901256
Original Research
Published
Identification of natural TLR4 modulators through network pharmacology and molecular modeling in SARS-CoV-2 Acinetobacter baumannii co-infection
Mebarka Ouassaf · Shafi Ullah Khan · Kannan R. R. Rengasamy · Nada S. Alhaggass · Bader Y. Alhatlani
Frontiers in Chemistry
doi 10.3389/fchem.2026.1916568
Frontiers in Science Viewpoint
Published
Is the glucose ketone index a biomarker of metabolic flexibility?
Shaminie J. Athinarayanan · Benjamin T. Bikman · Richard J. Johnson
Frontiers in Science
doi 10.3389/fsci.2026.1963812
Review
Published
The future directions of CAR-T Cell therapy: unlocking the potential of immunotherapy in cancer treatment
Angel Alberto Justiz-Vaillant · Sachin Soodeen · Rodolfo Arozarena-Fundora · Patrick Eberechi Akpaka · Chandrashekhar Unakal
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2026.1931159
Brief Research Report
Published
SST interneuron maturation extends beyond the second postnatal week and is driven by coordinated transcriptional and functional remodeling
Ourania Christodoulou · Konstantinos Diskos · Angeliki Velli · Panagiotis Moulos · Kyriaki Sidiropoulou · Myrto Denaxa
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1892850
Review
Published
Mitohormesis linking metabolic dysfunction and neurodegeneration: implications for dementia and therapeutic strategies
Toshiki Otoda · Hideto Nakajima · Tadateru Takayama
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1892506
Review
Published
Extracellular matrix and perineuronal nets in neural plasticity, memory, and epileptogenesis
Hanxiao Zhu · Qiongfen Li · Yun Li · Wei Wang
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1945520
Original Research
Published
Exploratory scaffold hopping strategies led to identification of novel histamine H 3 and H 4 receptor ligands
Flávia B. Lopes · Denise Mönnich · Gustavo A. B. Fernandes · Steffen Pockes · João Paulo S. Fernandes
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1944403
Review
Published
Molecular and ecological determinants of viral emergence in tropical regions: a One Health perspective integrating host–pathogen interactions, immune dysregulation, translational diagnostics, and epidemiological surveillance
Md Nazmul Hossen · Md Shamim Uddin · Md Imran Hossain · Md Shahriar Haque Noman · Tarin Naher
Frontiers in Tropical Diseases
doi 10.3389/fitd.2026.1849794
Original Research
Published
Electroacupuncture alleviates inflammatory pain by modulating the CXCL1/CXCR2 signaling axis in the spinal cord dorsal horn of rats
Xiazhen Xu · Ziyan Fang · Kaihua Song · Yang Shen · Chenxin Jiang · Mengchao Xu · Shouhai Hong
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1880288
Original Research
Published
A multi-residue electrostatic clamp in HIV-1 CRF01_AE Tat underlies high-affinity engagement with NMDA and hDAT receptors
Shaughn Dominic M. Padon · Ana Joy P. Lozano
Frontiers in Tropical Diseases
doi 10.3389/fitd.2026.1923721
Original Research
Published
Efficacy and safety of tapinarof cream once daily in Japanese pediatric patients with atopic dermatitis: a 60-week phase 3 trial consisting of an 8-week, double-blind, vehicle-controlled period and a 52-week, open-label extension period
Atsuyuki Igarashi · Gaku Tsuji · Ryusei Murata · Shuichi Fukasawa · Satoshi Yamane
Journal of Cutaneous Immunology and Allergy
doi 10.3389/jcia.2026.17307
Review
Published
Smart biomaterials for precision drug delivery: emerging strategies for site-specific targeting and controlled therapeutic release
Sivakumar Singaravelu · Rajkamal Balu · Chinnaiyan Senthilkumar · Jayabalan Jayaprakash
Frontiers in Biomaterials Science
doi 10.3389/fbiom.2026.1912922
Original Research
Published
Palmitoylation-related lncRNAs link molecular signaling, immune remodeling, and tumor progression in glioma: prognostic modeling and functional validation of LYRM4-AS1
Juan Xu · Chen Zhang · Lingling Pu · Xiaoyang Zhu · Xiaoan Sheng · Juanjuan Dong · Miaomiao Song · Chao Wang
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1901839
Brief Research Report
Published
A laboratory amitraz resistance assay for Varroa destructor may not be a reliable predictor of field-level amitraz efficacy
Devan Rawn · Kiley J. Epperson · James C. Fulton · Cameron J. Jack
Frontiers in Bee Science
doi 10.3389/frbee.2026.1886628
Review
Published
Guanfacine and HCN channels: bridging neuroinflammation and prefrontal cortex function in autism spectrum disorder
Kazuhiko Yamamuro · Takahira Yamauchi · Manabu Makinodan
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1915506
Original Research
Published
Distinct retinal oxygenation patterns in acute zonal occult outer retinopathy assessed by multimodal imaging
Scott Tschuppert · Christophe Valmaggia · Margarita G. Todorova
Frontiers in Neuroimaging
doi 10.3389/fnimg.2026.1902215
Original Research
Published
Therapeutic potential of Cola nitida against dexamethasone- and scopolamine-induced cognitive and cardiac dysfunction
Lawrence Dayo Adedayo · Olugbenga S. Michael · Gideon Opeyemi Ayilara · Mayode Elizabeth Olumoroti · Olubayode Bamidele · Saminu Samaila · Ibtihel Dhaya · Nafisat Dasola Akorede · Patrick Oluwole Abolarin · Laurette N. Ofodile
Frontiers in Behavioral Neuroscience
doi 10.3389/fnbeh.2026.1803200
Correction
Published
Correction: Hypoxia-induced metabolic shifting and AHR/BCRP axis impairment drive placental dysfunction in early-onset preeclampsia and FGR
Jingjing Shi · Wenxuan Zhu · Haixia Liu · Ping Yang · Yongzhong Gu · Wen Peng · Jinlai Meng
Frontiers in Toxicology
doi 10.3389/ftox.2026.1953267
Review
Published
Pathological neural and immune synapses in glioblastoma progression: mechanisms and therapeutic opportunities
Ashwin Jainarayanan · Aishwarya Vedula · Neeraj Soni
Frontiers in Neural Circuits
doi 10.3389/fncir.2026.1919817
Perspective
Published
Bridging AI, molecular dynamics, and experiments for mechanism-aware TCR engineering in cancer immunotherapy
Mario Frezzini · Daniele Narzi
Frontiers in Chemical Biology
doi 10.3389/fchbi.2026.1909618
Original Research
Published
Diversity of glutamate receptors in glial cells of the mouse optic nerve
Nine F. Kompier · Marcus Semtner · Sophie Walter · Christian Steinhäuser · Christiane Nolte · Helmut Kettenmann
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1911068
Brief Research Report
Published
Reversal of repetitive TMS-induced LTP-like plasticity by a novel compound in rats
Ugur Damar · Paul MacMullin · Sameer Dhamne · Alexander Rotenberg
Frontiers in Neural Circuits
doi 10.3389/fncir.2026.1925688
Original Research
Published
Revealing RELL1 signaling relying on the phosphoregulatory network analysis
Pathiyil Sajini Sekhar · Diya Sanjeev · Amal Fahma · Suhail Subair · Athira Perunally Gopalakrishnan · Prathik Basthikoppa Shivamurthy · Rajesh Raju · Sowmya Soman
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1939325
Case Report
Published
Case Report: Pembrolizumab–induced myasthenia gravis with isolated anti-titin antibody positivity after thymectomy for thymoma
Ju Hye Kim · Ji Yeon Chung · Jeong Bin Bong
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1932554