Review
Published
Analytical similarity as the primary determinant of monoclonal antibody development: toward evidence-efficient regulatory frameworks
Sarfaraz K. Niazi
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1801236
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 160 articles
Original Research
Published
Optimization of a malachite green–pyrophosphatase assay for the Zika virus RNA-dependent RNA polymerase and preliminary identification of natural product modulators
Vanessa Aitken · Anthony F. T. Moore · Manuel Terrazas-López · Salvador Rodarte · Eda Koculi
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1749327
Review
Published
Neuro-regulatory drug discovery (NRGDD): a neural-circuit framework for systemic therapeutic modulation
Sarfaraz K. Niazi
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1782364
Review
Published
Beyond GLP-1: underexplored peptide–receptor systems as the next frontier in drug discovery
Sarfaraz K. Niazi
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1792418
Review
Published
Traditional medicine and natural product based therapeutics in gingivitis management and microbial interactions
Pranita Rath · Sudipta Kumar Patra · Manisha Dash · Sandeep Kumar Behera · Shibani Mohapatra · Kabir Suman Dash · Alok Kumar Panda
Frontiers in Antibiotics
doi 10.3389/frabi.2026.1764314
Systematic Review
Published
Nanoparticle-mediated mRNA delivery for cancer, autoimmunity, and genetic diseases: a rapid review
Okechukwu Paul-Chima Ugwu · Fabian C. Ogenyi · Mariam Basajja · Chinyere N. Ugwu · Mundu M. Mustafa · Michael Ben Okon
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1793322
Mini Review
Published
Safety and efficacy of novel therapeutics in lupus: a narrative review
Michael F. Loncharich · Brenna E. Cafeo · Evan B. Noble
Frontiers in Lupus
doi 10.3389/flupu.2026.1800946
Mini Review
Published
Navigating the complexity of oral peptide delivery: challenges and strategies to enhance oral bioavailability
Noor-Ul-Ain Khalid · Edgardo Rivera-Delgado · Thomas von Erlach
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1809842
Review
Published
Genetics of epilepsy
Kynen Piacentini · Athanasios Gaitatzis · Sulev Kõks
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10933
Original Research
Published
Federating AI-related regulations for human therapeutics: an AI-enabled, continuously updating regulatory intelligence system
Rominder Singh · Mukesh Pareek · Michael Prokle · Eduardo Sanchez · Uwe Hohgrawe · Jared R. Auclair
Frontiers in Drug Safety and Regulation
doi 10.3389/fdsfr.2026.1718379
Original Research
Published
Multivalent display of membrane proteins using HIV-1 Gag VLPs
Neha A. Bhat · Nicholas Dunn · Xiaodi Yu · Matthew DuPrie · Supratik Dutta · Matthew McLean · Micheal D. Feldkamp · Jacqueline Kratch · Mandeep K. Mann · Simin Rahighi · Robert C. Davidson · John B. Leppard · Wan Cheung Cheung · Puneet Khandelwal
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1688204
Systematic Review
Published
Honeybee venom therapy and viral infection: a systematic synthesis of venom antiviral activity
Sirwan Sleman · Zaniar A. Abass · Barham J. Abdullah · Omed I. Abid · Masood B. Ameen
Frontiers in Virology
doi 10.3389/fviro.2026.1751614
Editorial
Published
Editorial: Emerging trends in phage therapeutics to overcome antibiotic resistance
William Calero-Cáceres · Ankush Gupta · Anju Kaushal · Paul Hyman
Frontiers in Antibiotics
doi 10.3389/frabi.2026.1788766
Mini Review
Published
Enhanced information processing in the human neocortex: cellular mechanisms and translational perspectives
Manuela Tore · Laura Monni · Alessio Di Clemente · Michele Giugliano
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2026.1770193
Review
Published
Bacterial pigments as sustainable and functional colorants in cosmetic applications: advances and prospects
Pritha Chakraborty · Mandheer Kaur · Basheer Thazeem · Jithin Thomas · Hemavathy S · Deepak Sharma
Frontiers in Bacteriology
doi 10.3389/fbrio.2026.1746114
Brief Research Report
Published
Validation of a torsinA cerebellar knockdown model of DYT1 dystonia
Yuning Liu · Hong Xing · Fumiaki Yokoi · Ariel Luz Walker · Duo Chen · Edgardo Rodriguez-Lebron · Yuqing Li
Dystonia
doi 10.3389/dyst.2026.14631
Review
Published
Brain network pathophysiology in dystonia
David A. Peterson · Myungjoo Kim · Robert Chen · David Eidelberg · Cecile Gallea · Andreas G. Horn · Stephane Lehericy · Anthony R. McIntosh · Joel S. Perlmutter · Anna Sadnicka · Terrence D. Sanger · Emiliano Santarnecchi · Philip A. Starr · Jan K. Teller · Mark Hallett · Kristina Simonyan
Dystonia
doi 10.3389/dyst.2025.15446
Review
Published
The impact of microbiome diversity and composition on host health and susceptibility to disease across amphibian life stages
Abigail J. Miller · Jamie Voyles
Frontiers in Amphibian and Reptile Science
doi 10.3389/famrs.2025.1666714
Perspective
Published
Acinetobacter baumannii: challenges presented by a drug-resistant pathogen
E.K. Goncalves · L.A. Ramos · A. Seibert · L.M. Ribeiro · S.L. McDuffie · M.C. Murray · S.E. Fiester
Frontiers in Bacteriology
doi 10.3389/fbrio.2025.1734537
Review
Published
RNA splicing in bone diseases: mechanisms, pathogenesis and therapeutics
Linlin Zheng · Hui Sun · Ning Li · Lianqing Wang · Tianchu Li · Qiaoli Zhai
Acta Biochimica Polonica
doi 10.3389/abp.2025.15819
Original Research
Published
Tunable dual-AAV sparse labeling of PV + retinal ganglion cells enables single-neuron projection by fMOST
Lingbo Zhou · Gao Tan · Yu Li · Man Yuan · Sen Jin · Wenhui Zhang · Qitian Wang · Yin Shen
Frontiers in Neural Circuits
doi 10.3389/fncir.2025.1740624
Perspective
Published
From molecules to minds – an integrative framework for living in space
Susan Ip-Jewell · Raj K. Badhan · Emmy Jewell · Surabhi Sonawane · Madhumitha Srenivasan
Frontiers in Space Technologies
doi 10.3389/frspt.2025.1725449
Mini Review
Published
Therapeutic applications of CRISPR-Cas9 gene editing
Aditya Bharti · Joann Mudge
Frontiers in Genome Editing
doi 10.3389/fgeed.2025.1724291
Mini Review
Published
Bridging Eras: integrating ancient remedies with modern biotechnology to combat Non-TB skin infections
Nisargkumar Teli · Kinjal Upadhyay
Frontiers in Natural Products
doi 10.3389/fntpr.2025.1686049
Mini Review
Published
Use of encapsulated dexamethasone sodium phosphate (eDSP) in chronic obstructive pulmonary disease, cystic fibrosis, and inflammatory bowel disorders
Biljana Horn · Giovanni Mambrini · Maureen Roden · Caralee Schaefer · Dirk Thye · Mauro Magnani
Frontiers in Drug Delivery
doi 10.3389/fddev.2025.1730142
Original Research
Published
New analogs of 5-substituted-2(1 H )-pyridone containing of natural amino acids as potential drugs in idiopathic pulmonary fibrosis. Investigation in silico and preliminary in vitro
Krystyna Dzierzbicka · Maria Skrzypkowska · Monika Gensicka-Kowalewska · Mateusz Daśko · Bartosz Słomiński
Acta Biochimica Polonica
doi 10.3389/abp.2025.15218
Epigenetics and Epigenomics
Published
Epigenetic repurposing of carbohydrate metabolic inhibitors for insulin resistance: targeting DNMT1 and HDAC3 for β-cell restoration
Muhammad Javid Iqbal · Luis A. Salazar
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1691949
Lupus
Published
Scavenger receptors: key players in the immunological puzzle of lupus
Sabine Hahn · Monika Chitre · Dominique Shepard · Romana Rashid · Zaida G. Ramirez-Ortiz
Frontiers in Lupus
doi 10.3389/flupu.2025.1679564
Molecular Medicine
Published
Antibody-drug conjugates targeting the cadherin, claudin and nectin families of adhesion molecules
Masuko Katoh · Yohann Loriot · Izuma Nakayama · Akinobu Hamada · Kohei Shitara · Masaru Katoh
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2025.1661016
Impact Journals
Published
Toward precision cardiovascular medicine: progressing basic and translational science
Rainer Schulz
Frontiers in Science
doi 10.3389/fsci.2025.1659045
Impact Journals
Published
Conventional and precision medicine: opposites or complementary ends?
Valentin Fuster · Filip K. Swirski · Girish N. Nadkarni
Frontiers in Science
doi 10.3389/fsci.2025.1701495
Science archive
Published
Molecular targets of cannabinoids and their derivatives in epilepsy – a review with focus on CBD
Sebastian Marciniak · Weronika Wasyluk · Andrzej Wojtak
Acta Biochimica Polonica
doi 10.3389/abp.2025.15251
Lab on a Chip Technologies
Published
Advancements and challenges in culturing patient-derived cancer cells for personalized therapeutics
Yatian Fu · Bee Luan Khoo · Chwee Teck Lim
Frontiers in Lab on a Chip Technologies
doi 10.3389/frlct.2025.1663420
Natural Products
Published
A review on integrative approaches in oncology: bridging ayurvedic medicine and modern cancer therapeutics
Sudhanshu Kumar Jha · Neha Singh · Ozasvi R. Shanker · Ishika Antil · Jaydeep Singh Baghel · Vittal Huddar · Richa Tripathi
Frontiers in Natural Products
doi 10.3389/fntpr.2025.1635197
Health Archive
Published
Behavioral signature of trihexyphenidyl in the TOR1A (DYT1) knockin mouse model of dystonia
Ahmad Abdal Qader · Yuping Donsante · Jeffrey E. Markowitz · H. A. Jinnah · Chethan Pandarinath · Ellen J. Hess
Dystonia
doi 10.3389/dyst.2025.15034
Biophysics
Published
Nanotribology of viruses reveals their adhesion strength and modality of motion on surfaces
Charles Ault · Claudia Simon · Irina B. Tsvetkova · Pedro J. De Pablo · Bogdan Dragnea
Frontiers in Biophysics
doi 10.3389/frbis.2025.1623880
Parasitology
Published
Guanine derivatives as promising candidates for the development of purine-based antimalarial drugs
Worlanyo Tashie · Harry P. de Koning · Nancy O. Duah-Quashie · Neils B. Quashie
Frontiers in Parasitology
doi 10.3389/fpara.2025.1634209
Neuroscience
Published
The gut and heart’s role in reward processing
Minel Arinel · Karim Abdelaal
Frontiers in Integrative Neuroscience
doi 10.3389/fnint.2025.1479923
Drug Delivery
Published
Gene hydrogel platforms for targeted skin therapy: bridging hereditary disorders, chronic wounds, and immune related skin diseases
Liangtao Li
Frontiers in Drug Delivery
doi 10.3389/fddev.2025.1598145
Drug Delivery
Published
Synergistic mechanotherapy and sonopermeation guided by mathematical modeling for solid tumor treatment
Marina Koutsi · Triantafyllos Stylianopoulos · Fotios Mpekris
Frontiers in Drug Delivery
doi 10.3389/fddev.2025.1549098
Drug Delivery
Published
The stealth effect from a medicinal chemist perspective: definition and updates
Domenico Fuoco
Frontiers in Drug Delivery
doi 10.3389/fddev.2025.1564120
Medical Engineering
Published
Whole secretome of mesenchymal stem cells is fully incorporated in lipid bicontinuous cubic phases
Sandra Barata-Antunes · Rui A. Sousa · António J. Salgado · Bruno F. B. Silva
Frontiers in Medical Engineering
doi 10.3389/fmede.2025.1397406
Synthetic Biology
Published
Genetic circuits in synthetic biology: broadening the toolbox of regulatory devices
Marik M. Müller · Katja M. Arndt · Stefan A. Hoffmann
Frontiers in Synthetic Biology
doi 10.3389/fsybi.2025.1548572
Bacteriology
Published
Blood microbiome and cardiometabolic disease: insights, therapeutic strategies, and future directions
Ikram Khan · Imran Khan · Ali Sher Bacha · Yu Xiaohui · Ping Xie · Xiao-dong Xie · Zhiqiang Li
Frontiers in Bacteriology
doi 10.3389/fbrio.2025.1541085
Malaria
Published
Malaria “chemoprevention and vaccination strategies” for children living in endemic areas of Africa: a review
Winnie Nambatya · Moses Ocan · Bjarne Robberstad · Jane Achan · Richard Idro
Frontiers in Malaria
doi 10.3389/fmala.2025.1336324
Molecular Medicine
Published
Editorial: Tuberculosis: host immunity, diagnostics and therapeutics
Anthony G. Tsolaki · Amy K. Barczak · Uday Kishore
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2025.1568256
Health Archive
Published
Cerebellar contributions to dystonia: unraveling the role of Purkinje cells and cerebellar nuclei
Nichelle N. Jackson · Jacob A. Stagray · Heather D. Snell
Dystonia
doi 10.3389/dyst.2025.14006
Arachnid Science
Published
Thou shalt not pass - arachnid venom peptides interacting with biological membranes
Yachen Wang · Shaodong Guo · Katie F. Jee · Volker Herzig
Frontiers in Arachnid Science
doi 10.3389/frchs.2024.1490313