Review
Published
Macrophage functional plasticity in periodontitis: microenvironmental regulation, disease progression, and therapeutic targeting
Ziqi Gu · Xinyu Li · Gulinur Awuti
Frontiers in Immunology
doi 10.3389/fimmu.2026.1973755
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Showing 4909 articles
Review
Published
Vector-borne zoonotic bacteria in Tunisia: from fragmented data to an integrated One Health surveillance framework
Mourad Ben Said · Rachid Selmi · Hanène Belkahia
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1951493
Review
Published
Hypoxia-inducible factor-1α–mediated metabolic reprogramming in sepsis-associated organ dysfunction: organ-specific metabolic mismatch and therapeutic perspectives
Yuge Wu · Jiantao Lu · Yue Mo · Yaoqi Xu · Xiaoxi Yan · Caifen Yan · Yingzhen Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1998563
Review
Published
Metabolic-epigenetic regulation of the HBV cccDNA reservoir: pathways underpinning viral persistence
Qing Peng · Liyuan Hao · Shenghao Li · Fei Yu · Na Li · Fanghang Ye · Xiaoyu Hu
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1968789
Review
Published
Histotripsy in tumor therapy: advances in non-thermal mechanical ablation, immune modulation, and clinical translation
Yangyang Ma · Xinan Long · Jiangpeng Cheng · Lizhi Niu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1858144
Review
Published
From correlation to causation: dissecting the detection methodologies of oral bacterial-fungal crosstalk in health and disease
Yixin Zhang · Nanyan Bian · Zhuojun Dong · Biao Ren · Juan Li
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1937704
Review
Published
Nutritional regulation of the tumor immune microenvironment: metabolic mechanisms, immunotherapy response, and nursing implications
Danwei Zhong · Congjue Li · Zunyao Xiao
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938564
Review
Published
Tebentafusp induces systemic immune activation, but tumor immune remodeling remains incompletely validated: a narrative review in metastatic uveal melanoma
Francesca Rifaldi · Filippo De Braud · Michele Del Vecchio · Lorenza Di Guardo
Frontiers in Immunology
doi 10.3389/fimmu.2026.1934256
Review
Published
Precision immuno-oncology in triple-negative breast cancer: from PD-L1 to multimodal biomarkers, ADC–ICI combinations, and global real-world integration
Jingna Wu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1911879
Review
Published
Epigenetic and mitochondrial regulation in kidney disease: emerging mechanisms and therapeutic opportunities
Atul Rawat · Narayan Prasad · Chandan Komalkumar · Harshit Singh · Saurabh Chaturvedi · Sultan Ahmed · Brijendra Kumar · Ravi Shankar Kushwaha
Frontiers in Immunology
doi 10.3389/fimmu.2026.1910925
Review
Published
Lactate dynamics at the Pseudomonas aeruginosa –host interface: bacterial metabolism, host defense, and emerging links to histone lactylation
Yi Jian · Zhijie Wu · Yuqiang Liang · Jin Cao · Mei Li · Fashuang Yang · Ke Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1979311
Mini Review
Published
Spatial heterogeneity in glioblastoma: linking single-cell and spatial multi-omics to vaccine immunotherapy
Juan Yuan · Yong Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1921816
Review
Published
Botanical polysaccharides as veterinary vaccine adjuvants: structure, receptors, and translational limits
Ran Guan · Chaoyun Yang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1982641
Review
Published
Microbial-derived metabolites in cancer: evidence boundaries, immune mechanisms and translational pathways
Xuefeng Shi · Shunjun Wang · Wenhao Ouyang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1947330
Brief Research Report
Published
Distinct spatial immune architectures in tumor and tumor-adjacent tissues of early-stage non-small cell lung cancer
Isabella Polic · Claudio Arrechedera · Jared K. Slone · Amanda Montoya · Emily Bontekoe · Peixin Jiang · Anika Patel · Tatiana V. Karpinets · Xiaogang Wu · Xingzhi Song · Qianyun Luo · Heladio Ibarguen · Auriole Tamegnon · Mei Jiang · Cara Haymaker · Annikka Weissferdt · Ara A. Vaporciyan · Lydia E. Kavraki · Tina Cascone · Ignacio Wistuba · Luisa Maren Solis Soto · John V. Heymach · Jianjun Zhang · Don L. Gibbons · Alexandre Reuben
Frontiers in Immunology
doi 10.3389/fimmu.2026.1981839
Review
Published
Ulvan, carrageenan, and fucoidan: comparative immunomodulatory mechanisms and future directions in major algal sulfated polysaccharides
Shuang Zhao · Zhangyi Xia · Jinlin Liu · Meijing Zhang · Maozi Lin · Guangmao Ding · Longchen Tang · Fang Su · Jingyi Sun · Chao Zhao
Frontiers in Immunology
doi 10.3389/fimmu.2026.1949951
Review
Published
CAR-T-cell therapy for autoimmune neurologic diseases
Yunhan Zhao · Yunyu Ding · Congfeng Tang · Zhengrong Wei · Yuqing Fan · Xianhui Hu · Jilong Yi
Frontiers in Immunology
doi 10.3389/fimmu.2026.1942249
Mini Review
Published
A proposed retinal venular immune gate: a mini review of perivascular macrophages and basement-membrane organization
Zhiqing Huang · Zijian Huang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1970491
Review
Published
Chimeric antigen receptor-engineered cell therapy for asthma: advances in targeting type 2 inflammation and translational challenges
Yifei Niu · Chenyang Jian · Peize Liu · Mengwei Wu · Haoyuan Li · Xu Li · Lili Zhi
Frontiers in Immunology
doi 10.3389/fimmu.2026.1979396
Review
Published
Epigenetic rewiring of immunological memory in cancer: heterogeneity, mechanisms, and therapeutic vulnerabilities
Wenna Liu · Xiaole Pan · Yujia Zhao · Zhimei Li · Dan Wu · Ying Liang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1890189
Review
Published
Progress in research on gut microbiota regulation of tumorigenesis, progression, and therapeutic response via inflammatory cytokines
Yan Liu · Dan Zang · Jun Chen
Frontiers in Immunology
doi 10.3389/fimmu.2026.1922678
Review
Published
Calcium-dependent conformational transitions and ligand binding regulation of C-reactive protein: a comprehensive review
Bin Cheng · Zhi-Xin Yao · Guo-Qiang Wu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1963529
Mini Review
Published
Cerebrospinal fluid metagenomic next-generation sequencing for culture-negative anaerobic central nervous system infection involving Prevotella oris : attribution challenges in low-biomass specimens
Yan Li · Minghua Fan · Yuyuan Hu · Yuhang Yang · Wenyuan Li · Wei Zhang · Yanhong Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1896093
Original Research
Published
Clinical-scale manufacturing of CD137+ enriched tumor-reactive T cells for glioblastoma in the CliniMACS Prodigy
Arina Riabinska · Elvira Criado-Moronati · Emre Balta · Denis Frison · Cristina Berganza-Irusqueta · Tümay Telatar · Donata Maciaczyk · Johanna Engeln · Laura Fischer · Marieke Domdey · Imran Siddiqui · Velita Miranda · Teresa Schmidt · Sied Kebir · Yahya Ahmadipour · Martin Glas · Ulrich Herrlinger · Matthias Schneider · Anna-Laura Potthoff · Marcus Czabanka · Thomas Broggini · Sofia Stenqvist · Lisa M. Nilsson · Jonas A. Nilsson · Martina Ott · Andrzej Dzionek · Ian R. Hardy
Frontiers in Immunology
doi 10.3389/fimmu.2026.1866645
Mini Review
Published
T-cell metabolic reprogramming in systemic lupus erythematosus: linking intracellular metabolism to effector differentiation and senescent-like/exhausted-like states
Yi Zou · Zhichu Ren · Yuki Kudo · Michihito Kono
Frontiers in Immunology
doi 10.3389/fimmu.2026.1961063
Mini Review
Published
Metabolic stress and macrophage efferocytosis in osteoarthritis: mechanisms and therapeutic implications
HaoYang Wu · DeChao Yuan · RenJian He · ShiWei Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1999085
Original Research
Published
An opsonic peptide promotes radiation-induced macrophage extracellular trap clearance to alleviate inflammation
Yongchan Lee · Gaifeng Ma · Dilara Aylar · Monowar Aziz · Ping Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1970645
Original Research
Published
Tumor-educated macrophages promote ferroptosis inhibition in pancreatic cancer via activating the p62-KEAP1-NRF2 pathway
Shouying Li · Dongxue Qi · Hanyang Yi · Lina Yang · Tonglei Xu · Wenkai Zhou · Weidong Xu · Ziheng Xu · Haodong Tang · Fangliang Xie · Chunfang Zhang · Xuyang Liang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938077
Systematic Review
Published
Global trends and hotspots of genetic research on non-syndromic cleft lip with or without cleft palate: a bibliometric and bioinformatics analysis
Yuxuan Shang · Mingjian Zhao · Shuangshuang Gao · Shikang Gao · Mengru Zhu
Frontiers in Genetics
doi 10.3389/fgene.2026.1907333
Hypothesis and Theory
Published
Economic impact of biomarker-based aging interventions on healthcare costs and individual value
Federico Felizzi
Frontiers in Genetics
doi 10.3389/fgene.2026.1814599
Review
Published
MicroRNA cargo of extracellular vesicles as mediators of immune dysregulation in pediatric immune thrombocytopenia: from pathogenetic drivers to biomarkers
Lucia Argenziano · Maria Maddalena Marrapodi · Giuseppe Di Feo · Oriana Di Domenico · Francesca Rossi · Alessandra Di Paola
Frontiers in Genetics
doi 10.3389/fgene.2026.1951187
Review
Published
Alcohol-induced placental vasculopathy reprograms the placental-fetal cardiovascular axis: angiogenic mechanisms linking maternal alcohol exposure to developmental cardiovascular programming
Elisa Cebral
Frontiers in Physiology
doi 10.3389/fphys.2026.1917947
Review
Published
Silencing without clearing: pharmacological modulation of the SASP in aging and disease
Lukas Fresser · Zofia Chrienova · Jan Gebrt · Patrik Oleksak · Kamil Kuca · Eugenie Nepovimova
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1911529
Review
Published
Flavonoids in cancer pharmacology: molecular mechanisms, tumor microenvironment regulation, and drug resistance
Zhengyuan Yu · Zhanyi Zhou · Ni Yin · Hongcheng Ge
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1969337
Original Research
Published
EfficientNet-CICA: a sports image classification model based on causal intervention channel attention
Junnan Yang · Shaocong Zhao
Frontiers in Physiology
doi 10.3389/fphys.2026.1905347
Original Research
Published
Breaking limits: rapid sea-to-summit ascent of Mount Everest (8,848 m) in 3 days 23 hours following normobaric-hypoxic pre-acclimatization and staged supplemental oxygen in a non-elite athlete
Irina Zelenkova
Frontiers in Physiology
doi 10.3389/fphys.2026.1873293
Original Research
Published
Berberine ameliorates thioacetamide-induced liver injury in zebrafish through PPARγ signaling and restores bile acid homeostasis
Peng Sun · Jun Wu · Xiaoyu Zhu · Yanshuang Ren · Zhanyi Zhou · Wenjian Zhen · Yuan Ma · Xue Ding · Menghan Huang · Yuying Zhang · Wei Gong · Hao Wang
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1881966
Review
Published
NEDD4-1: from molecular mechanisms to clinical translation in human diseases
Haifen Tian · Yongsheng Huang · Yun Liang · Chengjun Huang · Bingbing Wei · Chang-Neng Liao · Weijie Zhou
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1897001
Review
Published
Early life stress, lower urinary tract dysfunction, and respiratory disease: a proposed shared-mechanism framework
Tadanobu Chuyo Kamijo · Mayoko Tsuji
Frontiers in Physiology
doi 10.3389/fphys.2026.1929695
Original Research
Published
Knowledge, attitudes, and practices among users of GLP-1 receptor agonists in Saudi Arabia: a cross-sectional study
Abdullah A. Alshehri · Mohammed K. Al-Osaimi · Nawaf N. Al-Saeedi · Osama M. Al-Wagdani · Sultan S. Al-Zahrani · Fareed A. Alharthi · Ghadah H. Alshehri · Fahad H. Baali · Saeed Saad A. Alghamdi · Wael Y. Khawagi
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1912202
Review
Published
High-altitude gastric disorders: insights into maladaptation pathophysiological mechanisms, disease spectrum and prevention strategies
Huihui Shang · Rong Zhang · Youbang Xie · Airong Yang · Jing Wang
Frontiers in Physiology
doi 10.3389/fphys.2026.1944395
Original Research
Published
EGFR-TKI-associated colitis in non-small cell lung cancer: a retrospective characterization of clinical, radiographic, endoscopic, and histopathologic features
Shujun Wang · Chen Tan · Pufang Shi · Ya Li · Hefeng Zhan · Jiajing Li
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1935622
Original Research
Published
Taxifolin alleviates podocyte injury and macrophage chemotaxis associated with diabetic nephropathy by directly targeting RBP1 identified via multi-omics and machine learning
Zi-Xuan Wang · Wen-Xuan Wang · Qiong-Dan Liang · Ling-Dong Kong
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1933167
Original Research
Published
Physiologically-based pharmacokinetic model to predict pharmacokinetics of KY0467 in humans and guide dose selection in infants and children
Panpan Xie · Yanyan Yang · Xuemei He · Ming Yang · Zhixing Chen · Xi Weng · Aixin Shi
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1866331
Systematic Review
Published
Exercise programmes incorporating proximal kinetic-chain components in flexible flatfoot: a systematic review and meta-analysis of foot posture, neuromuscular, and dynamic outcomes
Zheyu Xiong · Jiguo Liang · Guanghua Li
Frontiers in Physiology
doi 10.3389/fphys.2026.1959545
Original Research
Published
Electroacupuncture pretreatment attenuates myocardial ischemia/reperfusion injury-induced ferroptosis via the p53/SLC7A11/GPX4 pathway
Jing Mao · Qian-Ru Guo · Yi-Pu Luo · Cong-Fei Liu · Zhen-Yang Cao · Yun-Tao Yu · Wen-Wei Wu · Xin-Yu Luan · Dan-Ning Xu · Hua Wang · Pu Chen · Song Wu
Frontiers in Physiology
doi 10.3389/fphys.2026.1928208
Systematic Review
Published
Effects of eccentric training on athletes’ explosive power: a systematic review and meta-analysis
Yugang Zhang · Lei Zhang · Baozhong Zhang · Min Sun · Yuan Zhuang · Ni Ma
Frontiers in Physiology
doi 10.3389/fphys.2026.1960414
Original Research
Published
Depression, anxiety, and cognitive function in patients with ischemic cerebrovascular disease: a cross-sectional study based on the Montreal Cognitive Assessment
Weiwen Chen · Yinan Zhuo
Frontiers in Neurology
doi 10.3389/fneur.2026.1854573