Mini Review
Published
Spatial heterogeneity in glioblastoma: linking single-cell and spatial multi-omics to vaccine immunotherapy
Juan Yuan · Yong Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1921816
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Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 7032 articles
Review
Published
Botanical polysaccharides as veterinary vaccine adjuvants: structure, receptors, and translational limits
Ran Guan · Chaoyun Yang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1982641
Review
Published
Microbial-derived metabolites in cancer: evidence boundaries, immune mechanisms and translational pathways
Xuefeng Shi · Shunjun Wang · Wenhao Ouyang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1947330
Original Research
Published
Low-frequency passive mechanical stimulation produces antidepressant-like effects in rats involving gut–brain axis modulation
Rong Gao · Wenjing Pu · Yifei Lv · Liqiong Liu · Yan Zhao · Hao Liu · Li Chen · Nan Guan · Hongen Li
Frontiers in Immunology
doi 10.3389/fimmu.2026.1928978
Original Research
Published
Donor–recipient Hepatitis B serological patterns and post-transplant HBV events in pediatric living donor liver transplantation: a single-center retrospective cohort with a nested case series
Ying Le · Haifeng Tang · Quanhai Zhang · Jiajun Weng · Lianbin Huang · Xiaoke Dai · Mingman Zhang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1977829
Original Research
Published
Early dynamics of eosinophils and the neutrophil-to-lymphocyte ratio are associated with severe immune-related adverse events during nivolumab therapy for metastatic renal cell carcinoma
Ondřej Fiala · Jan Králíček · Jindřich Kopecký · Michal Vočka · Tomas Buchler · Hana Študentová · Jana Obertová · Beáta Rondzíková · Martin Matějů · Dominik Šafčák · Matej Hrnčár · Peter Priester · Martina Spisarová · Anežka Zemánková · Radka Lohynská · Michaela Tkadlecová · Lucie Grmelová · Petr Stránský · Bohuslav Melichar · Patrik Palacka · Alexandr Poprach
Frontiers in Immunology
doi 10.3389/fimmu.2026.1944728
Brief Research Report
Published
Distinct spatial immune architectures in tumor and tumor-adjacent tissues of early-stage non-small cell lung cancer
Isabella Polic · Claudio Arrechedera · Jared K. Slone · Amanda Montoya · Emily Bontekoe · Peixin Jiang · Anika Patel · Tatiana V. Karpinets · Xiaogang Wu · Xingzhi Song · Qianyun Luo · Heladio Ibarguen · Auriole Tamegnon · Mei Jiang · Cara Haymaker · Annikka Weissferdt · Ara A. Vaporciyan · Lydia E. Kavraki · Tina Cascone · Ignacio Wistuba · Luisa Maren Solis Soto · John V. Heymach · Jianjun Zhang · Don L. Gibbons · Alexandre Reuben
Frontiers in Immunology
doi 10.3389/fimmu.2026.1981839
Review
Published
Ulvan, carrageenan, and fucoidan: comparative immunomodulatory mechanisms and future directions in major algal sulfated polysaccharides
Shuang Zhao · Zhangyi Xia · Jinlin Liu · Meijing Zhang · Maozi Lin · Guangmao Ding · Longchen Tang · Fang Su · Jingyi Sun · Chao Zhao
Frontiers in Immunology
doi 10.3389/fimmu.2026.1949951
Review
Published
CAR-T-cell therapy for autoimmune neurologic diseases
Yunhan Zhao · Yunyu Ding · Congfeng Tang · Zhengrong Wei · Yuqing Fan · Xianhui Hu · Jilong Yi
Frontiers in Immunology
doi 10.3389/fimmu.2026.1942249
Review
Published
Chimeric antigen receptor-engineered cell therapy for asthma: advances in targeting type 2 inflammation and translational challenges
Yifei Niu · Chenyang Jian · Peize Liu · Mengwei Wu · Haoyuan Li · Xu Li · Lili Zhi
Frontiers in Immunology
doi 10.3389/fimmu.2026.1979396
Original Research
Published
Serum SPP1 levels are associated with disease severity and 1-year mortality in primary Sjögren’s syndrome-associated interstitial lung disease
Yuting Li · Shenao Zhang · Xiaorui Ding · Qing Wang · Tong Ji · Hong Yao · Jinghong Dai
Frontiers in Immunology
doi 10.3389/fimmu.2026.1959993
Review
Published
Progress in research on gut microbiota regulation of tumorigenesis, progression, and therapeutic response via inflammatory cytokines
Yan Liu · Dan Zang · Jun Chen
Frontiers in Immunology
doi 10.3389/fimmu.2026.1922678
Review
Published
Calcium-dependent conformational transitions and ligand binding regulation of C-reactive protein: a comprehensive review
Bin Cheng · Zhi-Xin Yao · Guo-Qiang Wu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1963529
Original Research
Published
Clinical-scale manufacturing of CD137+ enriched tumor-reactive T cells for glioblastoma in the CliniMACS Prodigy
Arina Riabinska · Elvira Criado-Moronati · Emre Balta · Denis Frison · Cristina Berganza-Irusqueta · Tümay Telatar · Donata Maciaczyk · Johanna Engeln · Laura Fischer · Marieke Domdey · Imran Siddiqui · Velita Miranda · Teresa Schmidt · Sied Kebir · Yahya Ahmadipour · Martin Glas · Ulrich Herrlinger · Matthias Schneider · Anna-Laura Potthoff · Marcus Czabanka · Thomas Broggini · Sofia Stenqvist · Lisa M. Nilsson · Jonas A. Nilsson · Martina Ott · Andrzej Dzionek · Ian R. Hardy
Frontiers in Immunology
doi 10.3389/fimmu.2026.1866645
Mini Review
Published
Metabolic stress and macrophage efferocytosis in osteoarthritis: mechanisms and therapeutic implications
HaoYang Wu · DeChao Yuan · RenJian He · ShiWei Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1999085
Original Research
Published
An opsonic peptide promotes radiation-induced macrophage extracellular trap clearance to alleviate inflammation
Yongchan Lee · Gaifeng Ma · Dilara Aylar · Monowar Aziz · Ping Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1970645
Original Research
Published
Dried blood spot IP-10 as a biomarker of tuberculosis severity and treatment responses: results from a phase IIb trial of adjunctive acetylsalicylic acid and ibuprofen
Iselin Høgbakk Edlund · Noelia Alonso-Rodriguez · Chiara Sopegno · Judith Farrés · Nino Gogichadze · Lilibeth Arias · Kaori L Fonseca · Kennedy Otwombe · Ziyaad Waja · Tumelo Moloantoa · Natasha Pillay · Thabiso Seiphetlo · Neil Martinson · Cristina Vilaplana · Anne Ma Dyrhol-Riise
Frontiers in Immunology
doi 10.3389/fimmu.2026.1924239
Original Research
Published
Integrative single-cell and bulk transcriptomic analysis identifies monocyte/macrophage senescence-associated candidate genes in pulmonary arterial hypertension
Xiaojun Chen · Weibin Wu · Yilong Liu · Guili Lian · Qingquan Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938985
Original Research
Published
SCD1 inhibition promotes lipid peroxidation and enhances anti-PD-1 response in triple-negative breast cancer
Quentin Herrera Garfia · Aurélien Azam · Eric Bonneil · Laetitia Montero-Ruiz · Mohsen Momeni · Mohammad Farran · Robin Jehay · Nor Eddine Sounni
Frontiers in Immunology
doi 10.3389/fimmu.2026.1843935
Original Research
Published
Tumor-educated macrophages promote ferroptosis inhibition in pancreatic cancer via activating the p62-KEAP1-NRF2 pathway
Shouying Li · Dongxue Qi · Hanyang Yi · Lina Yang · Tonglei Xu · Wenkai Zhou · Weidong Xu · Ziheng Xu · Haodong Tang · Fangliang Xie · Chunfang Zhang · Xuyang Liang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938077
Systematic Review
Published
Global trends and hotspots of genetic research on non-syndromic cleft lip with or without cleft palate: a bibliometric and bioinformatics analysis
Yuxuan Shang · Mingjian Zhao · Shuangshuang Gao · Shikang Gao · Mengru Zhu
Frontiers in Genetics
doi 10.3389/fgene.2026.1907333
Original Research
Published
Multi-model genome-wide association analysis reveals natural allelic variation and candidate loci for kernel phytic acid content in quality protein maize
Sushil Kumar · Sourabh Kumar · Dinesh Kumar Saini · Rainy Rainy · Abhijit Kumar Das · Chikkappa G. Karjagi · Dharampaul Chaudhary · Shailendra Singh Gaurav · Ramesh Kumar
Frontiers in Genetics
doi 10.3389/fgene.2026.1925511
Review
Published
Silencing without clearing: pharmacological modulation of the SASP in aging and disease
Lukas Fresser · Zofia Chrienova · Jan Gebrt · Patrik Oleksak · Kamil Kuca · Eugenie Nepovimova
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1911529
Original Research
Published
EfficientNet-CICA: a sports image classification model based on causal intervention channel attention
Junnan Yang · Shaocong Zhao
Frontiers in Physiology
doi 10.3389/fphys.2026.1905347
Original Research
Published
Admission-based predictors of in-hospital AKI in HFrEF: a single-centre retrospective study
Feng Dai · Xiaomin Li · Zihe Wang · Siyu Tan · Fengyang Han · Xiang Song
Frontiers in Physiology
doi 10.3389/fphys.2026.1928628
Methods
Published
A high-throughput 96-well plate method to measure human uterine contractility
Emilie Huon · Justine Rayssac · Marie-Charlotte Lamau · Carole Abo · Gauthier Dietrich · Ylann Abrahami · Jordan Kouby · Julien Adam · Nicolas R. Chevalier
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1953934
Original Research
Published
Breaking limits: rapid sea-to-summit ascent of Mount Everest (8,848 m) in 3 days 23 hours following normobaric-hypoxic pre-acclimatization and staged supplemental oxygen in a non-elite athlete
Irina Zelenkova
Frontiers in Physiology
doi 10.3389/fphys.2026.1873293
Original Research
Published
New software for assessment and interpretation of pulmonary function tests in adults: a comparative validation study
Khadija Ayed · Mhamed Acheche · Juan Del Coso · Ismail Laher · Ayoub Saeidi · Anthony C. Hackney · Hassane Zouhal
Frontiers in Physiology
doi 10.3389/fphys.2026.1917497
Review
Published
NEDD4-1: from molecular mechanisms to clinical translation in human diseases
Haifen Tian · Yongsheng Huang · Yun Liang · Chengjun Huang · Bingbing Wei · Chang-Neng Liao · Weijie Zhou
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1897001
Review
Published
Early life stress, lower urinary tract dysfunction, and respiratory disease: a proposed shared-mechanism framework
Tadanobu Chuyo Kamijo · Mayoko Tsuji
Frontiers in Physiology
doi 10.3389/fphys.2026.1929695
Original Research
Published
Knowledge, attitudes, and practices among users of GLP-1 receptor agonists in Saudi Arabia: a cross-sectional study
Abdullah A. Alshehri · Mohammed K. Al-Osaimi · Nawaf N. Al-Saeedi · Osama M. Al-Wagdani · Sultan S. Al-Zahrani · Fareed A. Alharthi · Ghadah H. Alshehri · Fahad H. Baali · Saeed Saad A. Alghamdi · Wael Y. Khawagi
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1912202
Review
Published
High-altitude gastric disorders: insights into maladaptation pathophysiological mechanisms, disease spectrum and prevention strategies
Huihui Shang · Rong Zhang · Youbang Xie · Airong Yang · Jing Wang
Frontiers in Physiology
doi 10.3389/fphys.2026.1944395
Original Research
Published
EGFR-TKI-associated colitis in non-small cell lung cancer: a retrospective characterization of clinical, radiographic, endoscopic, and histopathologic features
Shujun Wang · Chen Tan · Pufang Shi · Ya Li · Hefeng Zhan · Jiajing Li
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1935622
Original Research
Published
Agreement between upper-arm and wrist cuff occlusion for the assessment of vascular reactivity by digital thermal monitoring
Hamidreza Mohammadi · Ali Hashemi · Timothy O’Brien · Hamed Ghoshouni · Hirofumi Tanaka · Robert A. Kloner · Morteza Naghavi
Frontiers in Physiology
doi 10.3389/fphys.2026.1961953
Original Research
Published
Taxifolin alleviates podocyte injury and macrophage chemotaxis associated with diabetic nephropathy by directly targeting RBP1 identified via multi-omics and machine learning
Zi-Xuan Wang · Wen-Xuan Wang · Qiong-Dan Liang · Ling-Dong Kong
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1933167
Original Research
Published
Physiologically-based pharmacokinetic model to predict pharmacokinetics of KY0467 in humans and guide dose selection in infants and children
Panpan Xie · Yanyan Yang · Xuemei He · Ming Yang · Zhixing Chen · Xi Weng · Aixin Shi
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1866331
Systematic Review
Published
Exercise programmes incorporating proximal kinetic-chain components in flexible flatfoot: a systematic review and meta-analysis of foot posture, neuromuscular, and dynamic outcomes
Zheyu Xiong · Jiguo Liang · Guanghua Li
Frontiers in Physiology
doi 10.3389/fphys.2026.1959545
Original Research
Published
Independent correlates of vancomycin steady-state trough concentration among patients undergoing combined CABG and valve surgery: observational findings for intra-aortic balloon pump support
Bei-bei Shao · Tao Feng · Ji-cheng Jiang · Wen-lu Xing · Ming Ni · Lu-lu Li · Chao Liu · Shu-ping Meng · Yong-cheng Ma · Ai-feng Wang
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1888382
Original Research
Published
Associations between spike velocity and physical characteristics in elite sitting volleyball players
Shaocheng Sun · Meiling Ren · Jinhu Yan
Frontiers in Physiology
doi 10.3389/fphys.2026.1992570
Original Research
Published
Quercetin attenuates polystyrene nanoplastic-induced intestinal barrier injury through modulation of macrophage inflammatory responses
Jian Kang · Heng Yang · Yan Wang · Xin Zhang · Chunyang Zhu · Yanhong Zhou · Yanqin Li
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1973458
Systematic Review
Published
Effects of eccentric training on athletes’ explosive power: a systematic review and meta-analysis
Yugang Zhang · Lei Zhang · Baozhong Zhang · Min Sun · Yuan Zhuang · Ni Ma
Frontiers in Physiology
doi 10.3389/fphys.2026.1960414
Original Research
Published
Reporting signals of selected extrapyramidal adverse events with four newer second-generation antipsychotics: a disproportionality analysis of FAERS spontaneous reports
Pan Ma · Qin Xiao · Yunpei Zhao · Xin Zhang · Huan Ma · Dan Chen · Linli Xie
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1921943
Original Research
Published
Whole-exome sequencing reveals cumulative rare variant burden associated with susceptibility to anti-tuberculosis drug-induced liver injury in a Han Chinese cohort
Yang Hao · Xiaoqing Zhang · Daiyun Huang · Shengyin Qin · Yunxiao Lin · Jianwen Ruan · Lu Shen · Na Zhang · Zhenting Wang · Cong Huai · Jianquan Zhang
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1952049
Original Research
Published
Depression, anxiety, and cognitive function in patients with ischemic cerebrovascular disease: a cross-sectional study based on the Montreal Cognitive Assessment
Weiwen Chen · Yinan Zhuo
Frontiers in Neurology
doi 10.3389/fneur.2026.1854573
Review
Published
P2Y 12 inhibition, adenosine signaling, and bone remodeling: differential skeletal pharmacology of antiplatelet agents
Zhuoqun Ma · Wei Luo · Yuanbo Li · Hong Li · Chaomin Li
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1897702
Mini Review
Published
From emergency myelopoiesis to trained immunity? Reframing post-stroke myeloid reprogramming along the brain-bone marrow axis
TongZhu Wei · YongJiu Wang
Frontiers in Neurology
doi 10.3389/fneur.2026.1976078
Original Research
Published
Clinical study of isokinetic training with joint control tasks on lower limb function in stroke patients with proprioceptive impairment: a preliminary randomized controlled trial
Zhendong Zhang · Huixian Yu · Ping Li · Na Li · Yumei Zhang
Frontiers in Neurology
doi 10.3389/fneur.2026.1881854
Perspective
Published
Precision targeting of type 2 inflammation in COPD: identifying candidates for dupilumab therapy
Kezhuo Zhong · Kaiying Lv · Qun Liang
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1971309