Review
Published
Precision immuno-oncology in triple-negative breast cancer: from PD-L1 to multimodal biomarkers, ADC–ICI combinations, and global real-world integration
Jingna Wu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1911879
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Showing 8583 articles
Original Research
Published
The effects of co-application of organic fertilizer and limestone powder on soil organic carbon and its fractions in rubber plantations: associations with microbial necromass carbon and Fe/Al oxides
Jifen Yang · Shunjun Geng · Xiaoling Shi · Qianghao Zhang · Chunxia Yang
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1970224
Original Research
Published
House dust mite drives biphasic immunomodulation of inflammatory dendritic epidermal cells via glucose metabolism in atopic dermatitis
Ying Zhao · Cuie Gao · Xin Sui · Lan Ge · Huan Wang · Sisi Deng · Qiquan Chen · Lu Liu · Jing Tian · Tong Mu · Li Wang · Zhiqiang Song
Frontiers in Immunology
doi 10.3389/fimmu.2026.1887390
Original Research
Published
The multifaceted role of SsrB in S . Typhi H58 during THP-1 macrophage infection
Marion Fernandez · Soham Deolankar · Moirangthem Kiran Singh · Parisa Zangoui · Linda J. Kenney
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1849419
Review
Published
Epigenetic and mitochondrial regulation in kidney disease: emerging mechanisms and therapeutic opportunities
Atul Rawat · Narayan Prasad · Chandan Komalkumar · Harshit Singh · Saurabh Chaturvedi · Sultan Ahmed · Brijendra Kumar · Ravi Shankar Kushwaha
Frontiers in Immunology
doi 10.3389/fimmu.2026.1910925
Review
Published
Lactate dynamics at the Pseudomonas aeruginosa –host interface: bacterial metabolism, host defense, and emerging links to histone lactylation
Yi Jian · Zhijie Wu · Yuqiang Liang · Jin Cao · Mei Li · Fashuang Yang · Ke Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1979311
Mini Review
Published
Spatial heterogeneity in glioblastoma: linking single-cell and spatial multi-omics to vaccine immunotherapy
Juan Yuan · Yong Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1921816
Review
Published
Botanical polysaccharides as veterinary vaccine adjuvants: structure, receptors, and translational limits
Ran Guan · Chaoyun Yang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1982641
Original Research
Published
Low-frequency passive mechanical stimulation produces antidepressant-like effects in rats involving gut–brain axis modulation
Rong Gao · Wenjing Pu · Yifei Lv · Liqiong Liu · Yan Zhao · Hao Liu · Li Chen · Nan Guan · Hongen Li
Frontiers in Immunology
doi 10.3389/fimmu.2026.1928978
Original Research
Published
Donor–recipient Hepatitis B serological patterns and post-transplant HBV events in pediatric living donor liver transplantation: a single-center retrospective cohort with a nested case series
Ying Le · Haifeng Tang · Quanhai Zhang · Jiajun Weng · Lianbin Huang · Xiaoke Dai · Mingman Zhang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1977829
Original Research
Published
Early dynamics of eosinophils and the neutrophil-to-lymphocyte ratio are associated with severe immune-related adverse events during nivolumab therapy for metastatic renal cell carcinoma
Ondřej Fiala · Jan Králíček · Jindřich Kopecký · Michal Vočka · Tomas Buchler · Hana Študentová · Jana Obertová · Beáta Rondzíková · Martin Matějů · Dominik Šafčák · Matej Hrnčár · Peter Priester · Martina Spisarová · Anežka Zemánková · Radka Lohynská · Michaela Tkadlecová · Lucie Grmelová · Petr Stránský · Bohuslav Melichar · Patrik Palacka · Alexandr Poprach
Frontiers in Immunology
doi 10.3389/fimmu.2026.1944728
Brief Research Report
Published
Distinct spatial immune architectures in tumor and tumor-adjacent tissues of early-stage non-small cell lung cancer
Isabella Polic · Claudio Arrechedera · Jared K. Slone · Amanda Montoya · Emily Bontekoe · Peixin Jiang · Anika Patel · Tatiana V. Karpinets · Xiaogang Wu · Xingzhi Song · Qianyun Luo · Heladio Ibarguen · Auriole Tamegnon · Mei Jiang · Cara Haymaker · Annikka Weissferdt · Ara A. Vaporciyan · Lydia E. Kavraki · Tina Cascone · Ignacio Wistuba · Luisa Maren Solis Soto · John V. Heymach · Jianjun Zhang · Don L. Gibbons · Alexandre Reuben
Frontiers in Immunology
doi 10.3389/fimmu.2026.1981839
Review
Published
Ulvan, carrageenan, and fucoidan: comparative immunomodulatory mechanisms and future directions in major algal sulfated polysaccharides
Shuang Zhao · Zhangyi Xia · Jinlin Liu · Meijing Zhang · Maozi Lin · Guangmao Ding · Longchen Tang · Fang Su · Jingyi Sun · Chao Zhao
Frontiers in Immunology
doi 10.3389/fimmu.2026.1949951
Mini Review
Published
A proposed retinal venular immune gate: a mini review of perivascular macrophages and basement-membrane organization
Zhiqing Huang · Zijian Huang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1970491
Review
Published
Chimeric antigen receptor-engineered cell therapy for asthma: advances in targeting type 2 inflammation and translational challenges
Yifei Niu · Chenyang Jian · Peize Liu · Mengwei Wu · Haoyuan Li · Xu Li · Lili Zhi
Frontiers in Immunology
doi 10.3389/fimmu.2026.1979396
Original Research
Published
Serum SPP1 levels are associated with disease severity and 1-year mortality in primary Sjögren’s syndrome-associated interstitial lung disease
Yuting Li · Shenao Zhang · Xiaorui Ding · Qing Wang · Tong Ji · Hong Yao · Jinghong Dai
Frontiers in Immunology
doi 10.3389/fimmu.2026.1959993
Review
Published
Epigenetic rewiring of immunological memory in cancer: heterogeneity, mechanisms, and therapeutic vulnerabilities
Wenna Liu · Xiaole Pan · Yujia Zhao · Zhimei Li · Dan Wu · Ying Liang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1890189
Review
Published
Progress in research on gut microbiota regulation of tumorigenesis, progression, and therapeutic response via inflammatory cytokines
Yan Liu · Dan Zang · Jun Chen
Frontiers in Immunology
doi 10.3389/fimmu.2026.1922678
Review
Published
Calcium-dependent conformational transitions and ligand binding regulation of C-reactive protein: a comprehensive review
Bin Cheng · Zhi-Xin Yao · Guo-Qiang Wu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1963529
Mini Review
Published
Cerebrospinal fluid metagenomic next-generation sequencing for culture-negative anaerobic central nervous system infection involving Prevotella oris : attribution challenges in low-biomass specimens
Yan Li · Minghua Fan · Yuyuan Hu · Yuhang Yang · Wenyuan Li · Wei Zhang · Yanhong Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1896093
Original Research
Published
Clinical-scale manufacturing of CD137+ enriched tumor-reactive T cells for glioblastoma in the CliniMACS Prodigy
Arina Riabinska · Elvira Criado-Moronati · Emre Balta · Denis Frison · Cristina Berganza-Irusqueta · Tümay Telatar · Donata Maciaczyk · Johanna Engeln · Laura Fischer · Marieke Domdey · Imran Siddiqui · Velita Miranda · Teresa Schmidt · Sied Kebir · Yahya Ahmadipour · Martin Glas · Ulrich Herrlinger · Matthias Schneider · Anna-Laura Potthoff · Marcus Czabanka · Thomas Broggini · Sofia Stenqvist · Lisa M. Nilsson · Jonas A. Nilsson · Martina Ott · Andrzej Dzionek · Ian R. Hardy
Frontiers in Immunology
doi 10.3389/fimmu.2026.1866645
Mini Review
Published
T-cell metabolic reprogramming in systemic lupus erythematosus: linking intracellular metabolism to effector differentiation and senescent-like/exhausted-like states
Yi Zou · Zhichu Ren · Yuki Kudo · Michihito Kono
Frontiers in Immunology
doi 10.3389/fimmu.2026.1961063
Original Research
Published
An opsonic peptide promotes radiation-induced macrophage extracellular trap clearance to alleviate inflammation
Yongchan Lee · Gaifeng Ma · Dilara Aylar · Monowar Aziz · Ping Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1970645
Original Research
Published
Dried blood spot IP-10 as a biomarker of tuberculosis severity and treatment responses: results from a phase IIb trial of adjunctive acetylsalicylic acid and ibuprofen
Iselin Høgbakk Edlund · Noelia Alonso-Rodriguez · Chiara Sopegno · Judith Farrés · Nino Gogichadze · Lilibeth Arias · Kaori L Fonseca · Kennedy Otwombe · Ziyaad Waja · Tumelo Moloantoa · Natasha Pillay · Thabiso Seiphetlo · Neil Martinson · Cristina Vilaplana · Anne Ma Dyrhol-Riise
Frontiers in Immunology
doi 10.3389/fimmu.2026.1924239
Original Research
Published
Integrative single-cell and bulk transcriptomic analysis identifies monocyte/macrophage senescence-associated candidate genes in pulmonary arterial hypertension
Xiaojun Chen · Weibin Wu · Yilong Liu · Guili Lian · Qingquan Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938985
Original Research
Published
SCD1 inhibition promotes lipid peroxidation and enhances anti-PD-1 response in triple-negative breast cancer
Quentin Herrera Garfia · Aurélien Azam · Eric Bonneil · Laetitia Montero-Ruiz · Mohsen Momeni · Mohammad Farran · Robin Jehay · Nor Eddine Sounni
Frontiers in Immunology
doi 10.3389/fimmu.2026.1843935
Original Research
Published
Tumor-educated macrophages promote ferroptosis inhibition in pancreatic cancer via activating the p62-KEAP1-NRF2 pathway
Shouying Li · Dongxue Qi · Hanyang Yi · Lina Yang · Tonglei Xu · Wenkai Zhou · Weidong Xu · Ziheng Xu · Haodong Tang · Fangliang Xie · Chunfang Zhang · Xuyang Liang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938077
Original Research
Published
Spatial analysis of placentae during congenital cytomegalovirus infection suggests distinct cellular profiles in immune and trophoblast cells: an exploratory study
Elise Sintim-Aboagye · Huy Quang Quach · Indrani Mukherjee · Will Sherman · Katelyn T. Nguyen · Neil Ferland · Sheila Farnan · Kamila Otrubova · Namisha Verma · Dawn Littlefield · Sohan Punia · Erica Johnson · Mark Blackstad · Mark R. Schleiss · Andrew P. Norgan · Clive M. Gray · Elizabeth Ann L. Enninga · Rana Chakraborty
Frontiers in Immunology
doi 10.3389/fimmu.2026.1885923
Systematic Review
Published
Global trends and hotspots of genetic research on non-syndromic cleft lip with or without cleft palate: a bibliometric and bioinformatics analysis
Yuxuan Shang · Mingjian Zhao · Shuangshuang Gao · Shikang Gao · Mengru Zhu
Frontiers in Genetics
doi 10.3389/fgene.2026.1907333
Methods
Published
A modular verification and validation framework for hybrid-capture next-generation sequencing HLA typing in clinical histocompatibility laboratories
Alice Scarpa · Diego Ferrarese · Samantha Guidotti · Veronica Scaglia · Angela Rossi
Frontiers in Genetics
doi 10.3389/fgene.2026.1959391
Original Research
Published
Multi-model genome-wide association analysis reveals natural allelic variation and candidate loci for kernel phytic acid content in quality protein maize
Sushil Kumar · Sourabh Kumar · Dinesh Kumar Saini · Rainy Rainy · Abhijit Kumar Das · Chikkappa G. Karjagi · Dharampaul Chaudhary · Shailendra Singh Gaurav · Ramesh Kumar
Frontiers in Genetics
doi 10.3389/fgene.2026.1925511
Original Research
Published
Cross-lineage anomaly detection of microRNA expression: a framework for deriving exploratory candidate biomarkers in sarcoma
Mritunjoy Dey · Piotr Remiszewski · Ewelina Perdas · Paweł Golik · Jakub Piątkowski · Anna M. Czarnecka
Frontiers in Genetics
doi 10.3389/fgene.2026.1907450
Review
Published
MicroRNA cargo of extracellular vesicles as mediators of immune dysregulation in pediatric immune thrombocytopenia: from pathogenetic drivers to biomarkers
Lucia Argenziano · Maria Maddalena Marrapodi · Giuseppe Di Feo · Oriana Di Domenico · Francesca Rossi · Alessandra Di Paola
Frontiers in Genetics
doi 10.3389/fgene.2026.1951187
Review
Published
Alcohol-induced placental vasculopathy reprograms the placental-fetal cardiovascular axis: angiogenic mechanisms linking maternal alcohol exposure to developmental cardiovascular programming
Elisa Cebral
Frontiers in Physiology
doi 10.3389/fphys.2026.1917947
Review
Published
Silencing without clearing: pharmacological modulation of the SASP in aging and disease
Lukas Fresser · Zofia Chrienova · Jan Gebrt · Patrik Oleksak · Kamil Kuca · Eugenie Nepovimova
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1911529
Original Research
Published
Different stimulation methods for the rat treadmill exercise model used in cardiovascular disease research
Yu Jiang · Lihua Fang · Jingwen Xiao · Qinfei Wei · Xiaona Lin · Yan Zhang
Frontiers in Physiology
doi 10.3389/fphys.2026.1905960
Review
Published
Flavonoids in cancer pharmacology: molecular mechanisms, tumor microenvironment regulation, and drug resistance
Zhengyuan Yu · Zhanyi Zhou · Ni Yin · Hongcheng Ge
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1969337
Original Research
Published
EfficientNet-CICA: a sports image classification model based on causal intervention channel attention
Junnan Yang · Shaocong Zhao
Frontiers in Physiology
doi 10.3389/fphys.2026.1905347
Original Research
Published
Admission-based predictors of in-hospital AKI in HFrEF: a single-centre retrospective study
Feng Dai · Xiaomin Li · Zihe Wang · Siyu Tan · Fengyang Han · Xiang Song
Frontiers in Physiology
doi 10.3389/fphys.2026.1928628
Methods
Published
A high-throughput 96-well plate method to measure human uterine contractility
Emilie Huon · Justine Rayssac · Marie-Charlotte Lamau · Carole Abo · Gauthier Dietrich · Ylann Abrahami · Jordan Kouby · Julien Adam · Nicolas R. Chevalier
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1953934
Original Research
Published
Fibrinolytic suppression and increased uterine artery resistance are associated with embryo resorption in DBA/2 mated CBA/J mice
Youchen Liu · Jingjing Wang · Boning Huang · Ping Tang · Fangle Liu · Yuying Zheng · Yilin Li · Huiyi Xie · Liuqing Lin · Xinrong Yang · Xiubing Zhang · Jie Gao · Baoqin Lin
Frontiers in Physiology
doi 10.3389/fphys.2026.1942168
Original Research
Published
Breaking limits: rapid sea-to-summit ascent of Mount Everest (8,848 m) in 3 days 23 hours following normobaric-hypoxic pre-acclimatization and staged supplemental oxygen in a non-elite athlete
Irina Zelenkova
Frontiers in Physiology
doi 10.3389/fphys.2026.1873293
Original Research
Published
New software for assessment and interpretation of pulmonary function tests in adults: a comparative validation study
Khadija Ayed · Mhamed Acheche · Juan Del Coso · Ismail Laher · Ayoub Saeidi · Anthony C. Hackney · Hassane Zouhal
Frontiers in Physiology
doi 10.3389/fphys.2026.1917497
Original Research
Published
Berberine ameliorates thioacetamide-induced liver injury in zebrafish through PPARγ signaling and restores bile acid homeostasis
Peng Sun · Jun Wu · Xiaoyu Zhu · Yanshuang Ren · Zhanyi Zhou · Wenjian Zhen · Yuan Ma · Xue Ding · Menghan Huang · Yuying Zhang · Wei Gong · Hao Wang
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1881966
Review
Published
NEDD4-1: from molecular mechanisms to clinical translation in human diseases
Haifen Tian · Yongsheng Huang · Yun Liang · Chengjun Huang · Bingbing Wei · Chang-Neng Liao · Weijie Zhou
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1897001
Review
Published
Early life stress, lower urinary tract dysfunction, and respiratory disease: a proposed shared-mechanism framework
Tadanobu Chuyo Kamijo · Mayoko Tsuji
Frontiers in Physiology
doi 10.3389/fphys.2026.1929695
Original Research
Published
Knowledge, attitudes, and practices among users of GLP-1 receptor agonists in Saudi Arabia: a cross-sectional study
Abdullah A. Alshehri · Mohammed K. Al-Osaimi · Nawaf N. Al-Saeedi · Osama M. Al-Wagdani · Sultan S. Al-Zahrani · Fareed A. Alharthi · Ghadah H. Alshehri · Fahad H. Baali · Saeed Saad A. Alghamdi · Wael Y. Khawagi
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1912202
Review
Published
High-altitude gastric disorders: insights into maladaptation pathophysiological mechanisms, disease spectrum and prevention strategies
Huihui Shang · Rong Zhang · Youbang Xie · Airong Yang · Jing Wang
Frontiers in Physiology
doi 10.3389/fphys.2026.1944395