Review
Published
Immunometabolic crosstalk between dysfunctional adipose tissue and the brain: implications for postoperative cognitive dysfunction in obesity
Ya-Jiao Hu · Juan Ni · Jin-Xi Zhang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1965479
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Showing 9019 articles
Original Research
Published
Endophytic Pseudomonas pergaminensis DR1 controls anthracnose and promotes growth of medicinal orchid Pleione bulbocodioides
Yun-Qiao Xie · Kai-Feng Tao · Neng-Qi Li · Jian Yue · Juan Su · Jiang-Yun Gao
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1909299
Original Research
Published
Mendelian randomization of gut microbiota and exploratory testing of preventive effect of commercial Rothia mucilaginosa in constipated mice
Peishi Jiang · Xiaoqing Yang · Chenghao Zhang · Yuwei Li · Chen Xu
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1941480
Review
Published
Glutamine metabolic reprogramming in acute and chronic kidney diseases: mechanistic insights and therapeutic implications
Ruotong Xu · Jin Zhao · Minna Liu · Yifan Qiao · Xiaoxuan Ning · Shiren Sun
Frontiers in Immunology
doi 10.3389/fimmu.2026.1939528
Review
Published
Recombinant bacterial β -galactosidases for lactose bioconversion and galacto-oligosaccharide production: a comparative overview
Anel Kostanova · Yuliya Shamsiyeva · Zhiger Akishev · Bekbolat Khassenov · Annelya Tursunbekova
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1943869
Original Research
Published
Machine learning–based validation of Human Phenotype Ontology (HPO) terms for systemic autoinflammatory diseases using the Eurofever Registry: the ODINO project
Caterina Matucci-Cerinic · Giacomo Cavalca · Matteo Vergani · Roberta Caorsi · Marielle van Gjin · Guilaine Boursier · Eugenia Mosci · Giovanni Fiorito · Paolo Uva · Marco Gattorno
Frontiers in Immunology
doi 10.3389/fimmu.2026.1936099
Mini Review
Published
Inoculum-dependent activity of contemporary β-lactam agents against carbapenemase- producing Enterobacterales
Tokeshwar Kumar Sahu · Pravin Gadkari · Jaishriram Rathored
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1964408
Review
Published
Macrophage functional plasticity in periodontitis: microenvironmental regulation, disease progression, and therapeutic targeting
Ziqi Gu · Xinyu Li · Gulinur Awuti
Frontiers in Immunology
doi 10.3389/fimmu.2026.1973755
Review
Published
Vector-borne zoonotic bacteria in Tunisia: from fragmented data to an integrated One Health surveillance framework
Mourad Ben Said · Rachid Selmi · Hanène Belkahia
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1951493
Review
Published
Hypoxia-inducible factor-1α–mediated metabolic reprogramming in sepsis-associated organ dysfunction: organ-specific metabolic mismatch and therapeutic perspectives
Yuge Wu · Jiantao Lu · Yue Mo · Yaoqi Xu · Xiaoxi Yan · Caifen Yan · Yingzhen Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1998563
Review
Published
Metabolic-epigenetic regulation of the HBV cccDNA reservoir: pathways underpinning viral persistence
Qing Peng · Liyuan Hao · Shenghao Li · Fei Yu · Na Li · Fanghang Ye · Xiaoyu Hu
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1968789
Review
Published
From correlation to causation: dissecting the detection methodologies of oral bacterial-fungal crosstalk in health and disease
Yixin Zhang · Nanyan Bian · Zhuojun Dong · Biao Ren · Juan Li
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1937704
Review
Published
Nutritional regulation of the tumor immune microenvironment: metabolic mechanisms, immunotherapy response, and nursing implications
Danwei Zhong · Congjue Li · Zunyao Xiao
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938564
Original Research
Published
Spontaneous wbbL and waaG mutations selected by phage vB_EcoP_P61425 confer resistance and attenuate virulence in ExPEC
Long Chen · Sixiang Xu · Xiaoyue Li · Pei Li · Mengmeng Su · Peifan Liu · Yilin Fang · Wei Zhang
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1953743
Original Research
Published
An exploratory study of gut microbiota and serum metabolite profiles in type 2 diabetes patients with sleep disorders
Jinkun Ma · Xinbin Zhang · Yirao Pan · Xueli Bao · Hua Yi · Jing Hua · Qianqian Mu · Lantian Liu · Chunyu Hu · Dandan Zhao · Sihua Gao
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1911955
Review
Published
Tebentafusp induces systemic immune activation, but tumor immune remodeling remains incompletely validated: a narrative review in metastatic uveal melanoma
Francesca Rifaldi · Filippo De Braud · Michele Del Vecchio · Lorenza Di Guardo
Frontiers in Immunology
doi 10.3389/fimmu.2026.1934256
Review
Published
Precision immuno-oncology in triple-negative breast cancer: from PD-L1 to multimodal biomarkers, ADC–ICI combinations, and global real-world integration
Jingna Wu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1911879
Original Research
Published
The effects of co-application of organic fertilizer and limestone powder on soil organic carbon and its fractions in rubber plantations: associations with microbial necromass carbon and Fe/Al oxides
Jifen Yang · Shunjun Geng · Xiaoling Shi · Qianghao Zhang · Chunxia Yang
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1970224
Original Research
Published
House dust mite drives biphasic immunomodulation of inflammatory dendritic epidermal cells via glucose metabolism in atopic dermatitis
Ying Zhao · Cuie Gao · Xin Sui · Lan Ge · Huan Wang · Sisi Deng · Qiquan Chen · Lu Liu · Jing Tian · Tong Mu · Li Wang · Zhiqiang Song
Frontiers in Immunology
doi 10.3389/fimmu.2026.1887390
Original Research
Published
The multifaceted role of SsrB in S . Typhi H58 during THP-1 macrophage infection
Marion Fernandez · Soham Deolankar · Moirangthem Kiran Singh · Parisa Zangoui · Linda J. Kenney
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1849419
Review
Published
Epigenetic and mitochondrial regulation in kidney disease: emerging mechanisms and therapeutic opportunities
Atul Rawat · Narayan Prasad · Chandan Komalkumar · Harshit Singh · Saurabh Chaturvedi · Sultan Ahmed · Brijendra Kumar · Ravi Shankar Kushwaha
Frontiers in Immunology
doi 10.3389/fimmu.2026.1910925
Review
Published
Lactate dynamics at the Pseudomonas aeruginosa –host interface: bacterial metabolism, host defense, and emerging links to histone lactylation
Yi Jian · Zhijie Wu · Yuqiang Liang · Jin Cao · Mei Li · Fashuang Yang · Ke Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1979311
Mini Review
Published
Spatial heterogeneity in glioblastoma: linking single-cell and spatial multi-omics to vaccine immunotherapy
Juan Yuan · Yong Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1921816
Review
Published
Botanical polysaccharides as veterinary vaccine adjuvants: structure, receptors, and translational limits
Ran Guan · Chaoyun Yang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1982641
Review
Published
Microbial-derived metabolites in cancer: evidence boundaries, immune mechanisms and translational pathways
Xuefeng Shi · Shunjun Wang · Wenhao Ouyang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1947330
Original Research
Published
Low-frequency passive mechanical stimulation produces antidepressant-like effects in rats involving gut–brain axis modulation
Rong Gao · Wenjing Pu · Yifei Lv · Liqiong Liu · Yan Zhao · Hao Liu · Li Chen · Nan Guan · Hongen Li
Frontiers in Immunology
doi 10.3389/fimmu.2026.1928978
Original Research
Published
Donor–recipient Hepatitis B serological patterns and post-transplant HBV events in pediatric living donor liver transplantation: a single-center retrospective cohort with a nested case series
Ying Le · Haifeng Tang · Quanhai Zhang · Jiajun Weng · Lianbin Huang · Xiaoke Dai · Mingman Zhang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1977829
Original Research
Published
Early dynamics of eosinophils and the neutrophil-to-lymphocyte ratio are associated with severe immune-related adverse events during nivolumab therapy for metastatic renal cell carcinoma
Ondřej Fiala · Jan Králíček · Jindřich Kopecký · Michal Vočka · Tomas Buchler · Hana Študentová · Jana Obertová · Beáta Rondzíková · Martin Matějů · Dominik Šafčák · Matej Hrnčár · Peter Priester · Martina Spisarová · Anežka Zemánková · Radka Lohynská · Michaela Tkadlecová · Lucie Grmelová · Petr Stránský · Bohuslav Melichar · Patrik Palacka · Alexandr Poprach
Frontiers in Immunology
doi 10.3389/fimmu.2026.1944728
Brief Research Report
Published
Distinct spatial immune architectures in tumor and tumor-adjacent tissues of early-stage non-small cell lung cancer
Isabella Polic · Claudio Arrechedera · Jared K. Slone · Amanda Montoya · Emily Bontekoe · Peixin Jiang · Anika Patel · Tatiana V. Karpinets · Xiaogang Wu · Xingzhi Song · Qianyun Luo · Heladio Ibarguen · Auriole Tamegnon · Mei Jiang · Cara Haymaker · Annikka Weissferdt · Ara A. Vaporciyan · Lydia E. Kavraki · Tina Cascone · Ignacio Wistuba · Luisa Maren Solis Soto · John V. Heymach · Jianjun Zhang · Don L. Gibbons · Alexandre Reuben
Frontiers in Immunology
doi 10.3389/fimmu.2026.1981839
Review
Published
Ulvan, carrageenan, and fucoidan: comparative immunomodulatory mechanisms and future directions in major algal sulfated polysaccharides
Shuang Zhao · Zhangyi Xia · Jinlin Liu · Meijing Zhang · Maozi Lin · Guangmao Ding · Longchen Tang · Fang Su · Jingyi Sun · Chao Zhao
Frontiers in Immunology
doi 10.3389/fimmu.2026.1949951
Review
Published
CAR-T-cell therapy for autoimmune neurologic diseases
Yunhan Zhao · Yunyu Ding · Congfeng Tang · Zhengrong Wei · Yuqing Fan · Xianhui Hu · Jilong Yi
Frontiers in Immunology
doi 10.3389/fimmu.2026.1942249
Mini Review
Published
A proposed retinal venular immune gate: a mini review of perivascular macrophages and basement-membrane organization
Zhiqing Huang · Zijian Huang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1970491
Review
Published
Chimeric antigen receptor-engineered cell therapy for asthma: advances in targeting type 2 inflammation and translational challenges
Yifei Niu · Chenyang Jian · Peize Liu · Mengwei Wu · Haoyuan Li · Xu Li · Lili Zhi
Frontiers in Immunology
doi 10.3389/fimmu.2026.1979396
Original Research
Published
Serum SPP1 levels are associated with disease severity and 1-year mortality in primary Sjögren’s syndrome-associated interstitial lung disease
Yuting Li · Shenao Zhang · Xiaorui Ding · Qing Wang · Tong Ji · Hong Yao · Jinghong Dai
Frontiers in Immunology
doi 10.3389/fimmu.2026.1959993
Review
Published
Epigenetic rewiring of immunological memory in cancer: heterogeneity, mechanisms, and therapeutic vulnerabilities
Wenna Liu · Xiaole Pan · Yujia Zhao · Zhimei Li · Dan Wu · Ying Liang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1890189
Review
Published
Progress in research on gut microbiota regulation of tumorigenesis, progression, and therapeutic response via inflammatory cytokines
Yan Liu · Dan Zang · Jun Chen
Frontiers in Immunology
doi 10.3389/fimmu.2026.1922678
Review
Published
Calcium-dependent conformational transitions and ligand binding regulation of C-reactive protein: a comprehensive review
Bin Cheng · Zhi-Xin Yao · Guo-Qiang Wu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1963529
Mini Review
Published
Cerebrospinal fluid metagenomic next-generation sequencing for culture-negative anaerobic central nervous system infection involving Prevotella oris : attribution challenges in low-biomass specimens
Yan Li · Minghua Fan · Yuyuan Hu · Yuhang Yang · Wenyuan Li · Wei Zhang · Yanhong Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1896093
Mini Review
Published
T-cell metabolic reprogramming in systemic lupus erythematosus: linking intracellular metabolism to effector differentiation and senescent-like/exhausted-like states
Yi Zou · Zhichu Ren · Yuki Kudo · Michihito Kono
Frontiers in Immunology
doi 10.3389/fimmu.2026.1961063
Mini Review
Published
Metabolic stress and macrophage efferocytosis in osteoarthritis: mechanisms and therapeutic implications
HaoYang Wu · DeChao Yuan · RenJian He · ShiWei Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1999085
Original Research
Published
An opsonic peptide promotes radiation-induced macrophage extracellular trap clearance to alleviate inflammation
Yongchan Lee · Gaifeng Ma · Dilara Aylar · Monowar Aziz · Ping Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1970645
Original Research
Published
Dried blood spot IP-10 as a biomarker of tuberculosis severity and treatment responses: results from a phase IIb trial of adjunctive acetylsalicylic acid and ibuprofen
Iselin Høgbakk Edlund · Noelia Alonso-Rodriguez · Chiara Sopegno · Judith Farrés · Nino Gogichadze · Lilibeth Arias · Kaori L Fonseca · Kennedy Otwombe · Ziyaad Waja · Tumelo Moloantoa · Natasha Pillay · Thabiso Seiphetlo · Neil Martinson · Cristina Vilaplana · Anne Ma Dyrhol-Riise
Frontiers in Immunology
doi 10.3389/fimmu.2026.1924239
Original Research
Published
Integrative single-cell and bulk transcriptomic analysis identifies monocyte/macrophage senescence-associated candidate genes in pulmonary arterial hypertension
Xiaojun Chen · Weibin Wu · Yilong Liu · Guili Lian · Qingquan Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938985
Original Research
Published
SCD1 inhibition promotes lipid peroxidation and enhances anti-PD-1 response in triple-negative breast cancer
Quentin Herrera Garfia · Aurélien Azam · Eric Bonneil · Laetitia Montero-Ruiz · Mohsen Momeni · Mohammad Farran · Robin Jehay · Nor Eddine Sounni
Frontiers in Immunology
doi 10.3389/fimmu.2026.1843935
Original Research
Published
Tumor-educated macrophages promote ferroptosis inhibition in pancreatic cancer via activating the p62-KEAP1-NRF2 pathway
Shouying Li · Dongxue Qi · Hanyang Yi · Lina Yang · Tonglei Xu · Wenkai Zhou · Weidong Xu · Ziheng Xu · Haodong Tang · Fangliang Xie · Chunfang Zhang · Xuyang Liang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938077
Original Research
Published
Spatial analysis of placentae during congenital cytomegalovirus infection suggests distinct cellular profiles in immune and trophoblast cells: an exploratory study
Elise Sintim-Aboagye · Huy Quang Quach · Indrani Mukherjee · Will Sherman · Katelyn T. Nguyen · Neil Ferland · Sheila Farnan · Kamila Otrubova · Namisha Verma · Dawn Littlefield · Sohan Punia · Erica Johnson · Mark Blackstad · Mark R. Schleiss · Andrew P. Norgan · Clive M. Gray · Elizabeth Ann L. Enninga · Rana Chakraborty
Frontiers in Immunology
doi 10.3389/fimmu.2026.1885923
Systematic Review
Published
Global trends and hotspots of genetic research on non-syndromic cleft lip with or without cleft palate: a bibliometric and bioinformatics analysis
Yuxuan Shang · Mingjian Zhao · Shuangshuang Gao · Shikang Gao · Mengru Zhu
Frontiers in Genetics
doi 10.3389/fgene.2026.1907333
Hypothesis and Theory
Published
Economic impact of biomarker-based aging interventions on healthcare costs and individual value
Federico Felizzi
Frontiers in Genetics
doi 10.3389/fgene.2026.1814599