Original ResearchPublished 8 October 2026Assessment of the transcriptional and cellular effects of CRISPRa targeting Dopa decarboxylase and GTP cyclohydrolase 1 in HEK293 and SH-SY5Y cellular models of Parkinsonian neurotoxicitySiyethaba Zinhle Bhengu · Ravesh Singh · Veron Ramsuran · Zama Ndlondlo Princess MsibiFrontiers in Cellular Neurosciencedoi 10.3389/fncel.2026.1883789
MethodsPublished 20 May 2026A high-throughput, streamlined cloning protocol to generate guide RNAs for CRISPR activationShusen Zhu · Aura A. Tamez González · Abdelrahman Alokda · Jeremy M. Van RaamsdonkFrontiers in Genome Editingdoi 10.3389/fgeed.2026.1787203