Original ResearchPublished 8 October 2026Assessment of the transcriptional and cellular effects of CRISPRa targeting Dopa decarboxylase and GTP cyclohydrolase 1 in HEK293 and SH-SY5Y cellular models of Parkinsonian neurotoxicitySiyethaba Zinhle Bhengu · Ravesh Singh · Veron Ramsuran · Zama Ndlondlo Princess MsibiFrontiers in Cellular Neurosciencedoi 10.3389/fncel.2026.1883789
Original ResearchPublished 18 September 2026A novel minimally humanized mouse model of aniridia for preclinical evaluation of CRISPR gene editing strategiesSeyedeh Zeinab Mirjalili Mohanna · Andrea J. Korecki · Pardis Kazemian · Tess C. Lengyell · Bethany A. Adair · Blair R. Leavitt · Elizabeth M. SimpsonFrontiers in Genome Editingdoi 10.3389/fgeed.2026.1910209
MethodsPublished 20 May 2026A high-throughput, streamlined cloning protocol to generate guide RNAs for CRISPR activationShusen Zhu · Aura A. Tamez González · Abdelrahman Alokda · Jeremy M. Van RaamsdonkFrontiers in Genome Editingdoi 10.3389/fgeed.2026.1787203
