Articles

Showing 65 articles

• Review

  Published 12 October 2026

  Tavapadon in Parkinson’s disease: D1/D5 receptor pharmacology, clinical evidence, and translational perspectives

  Mohamed Alsharif · Omran Shrebaty · Mohammad Oudah · Raghad Saud AlOubili · Dalal Mohammed Akram Motabagani · Jenan M. Alnamly · Gadi Khalid Sindi · Ahmad E. L. Bana

  Frontiers in Aging Neuroscience

  doi 10.3389/fnagi.2026.1959744

• Original Research

  Published 12 October 2026

  Sex differences in electrocardiographic patterns among patients with acute coronary syndromes

  Francesco Vitali · Giorgia Azzolini · Marco Zuin · Nicola Bianchi · Michele Malagù · Martina De Raffele · Anna Cantone · Federico Sanguettoli · Federico Gibiino · Cristina Balla · Elisabetta Tonet · Rita Pavasini · Gianluca Campo · Matteo Bertini

  Frontiers in Cardiovascular Medicine

  doi 10.3389/fcvm.2026.1758485

• Original Research

  Published 12 October 2026

  Age-specific agreement between Hi-DongDong and UTAP-2 articulation assessments in Korean children aged 2–13 years

  Jinju Lee · Sejin Kwon · Jin Young Ko · Yulhyun Park · Jaewon Lee · Ju Seok Ryu · Jee Hyun Suh

  Frontiers in Pediatrics

  doi 10.3389/fped.2026.1944143

• Original Research

  Published 12 October 2026

  Barrier and no-touch techniques in gastrointestinal surgery: a best evidence summary

  Qingqing Du · Hailei Bian · Shan Wu · Fangyuan Sun · Li Ni

  Frontiers in Surgery

  doi 10.3389/fsurg.2026.1948728

• Clinical Trial

  Published 12 October 2026

  Preliminary evaluation of ProSpare ® , a rectal obturator for prostate bed radiotherapy within the randomised multicentre POPS trial (NCT02978014)

  Sarah Stewart · Karen Thomas · Jenni Parmar · Alison Claire Tree · Chris Parker · Helen McNair · Sophie Alexander · Julia Henderson · James Talbot · Christopher Scrase · Chee Goh · Reena Davda · Emma Gray · Peter Hoskin · Sarah Needleman · Jenny Nobes · Kamalram Thippu Jayaprakash · Yvonne Rimmer · Ranachandran Venkitaraman · Anna Wilkins · Vincent Khoo · Julia Murray · David Paul Dearnaley

  Frontiers in Oncology

  doi 10.3389/fonc.2026.1758462

• Study Protocol

  Published 9 October 2026

  Effect of epidural spinal cord stimulation combined with personalized neurorehabilitation in chronic motor-complete spinal cord injury: study protocol for the phase II single-arm feasibility RESTORES (RESToration Of Rehabilitative function with Epidural spinal Stimulation) trial

  Kai Rui Wan · Zhi Yan Valerie Ng · Seng Kwee Wee · Fatimah Misbaah · Wen Li Lui · Min Wee Phua · Tegan Plunkett · Neethu Robinson · Aung Aung Phyo Wai · Cuntai Guan · Ananda Sidarta · Rosa Qi Yue So · Brian Premchand · Kezia Susanto · Luca Cocchi · Seyed Ehsan Saffari · Rui Xin Justin Ker · Wai Hoe Ng

  Frontiers in Neurology

  doi 10.3389/fneur.2026.1967078

• Systematic Review

  Published 9 October 2026

  Mapping the methodological framework of diabetic retinopathy interventional trials: a scoping review on trial design, execution, and reporting practices

  Zixuan Wang · Xuwei Liu · Ming Yang · Guanchi Yan · Xuechun Fan · Jing Yu · Jinyue Zhao · Yingjing Shi · Xi Chen

  Frontiers in Endocrinology

  doi 10.3389/fendo.2026.1961622

• Original Research

  Published 9 October 2026

  Therapeutic alliance and predictive validity of reflective functioning in conjoint mentalization-based treatment for borderline personality disorder

  Dag Anders Ulvestad · Elfrida Hartveit Kvarstein · Andreas Ekberg · Peder Ludvig Sætre · Geir Pedersen · Theresa Wilberg

  Frontiers in Psychology

  doi 10.3389/fpsyg.2026.1919516

• Study Protocol

  Published 9 October 2026

  Cognitive remediation in schizophrenia: efficacy and role of neuroplasticity in “top-down” and “bottom-up” mechanisms—a randomized, double-blind, treatment-as-usual-controlled study protocol

  Juan I. Cifuentes · Constanza Orellana · Diego Tello · Cristian Ramírez · Catalina Prieto · Jessica M. Guasti · Rodrigo R. Nieto

  Frontiers in Psychiatry

  doi 10.3389/fpsyt.2026.1936475

• Systematic Review

  Published 8 October 2026

  Antimalarial and antiplasmodial compounds (2024–2026): a systematic review of synthetic, semi-synthetic, and natural agents

  Bertin Mikolo · Gelase Fredy Nsonde Ntandou · Hermeline Tabuna Nee Ntalani

  Frontiers in Tropical Diseases

  doi 10.3389/fitd.2026.1944733

• Original Research

  Published 8 October 2026

  A personalized nutrition intervention advances meal timing and is associated with reduced postprandial lipid and inflammatory responses in night shift workers

  Maaike van der Rhee · Tim J. van den Broek · Inês Chaves · Martijn E. T. Dollé · Linda W. M. van Kerkhof · Alex Burdorf · Heidi M. Lammers-Van der Holst · Johanneke E. Oosterman · Suzan Wopereis

  Frontiers in Nutrition

  doi 10.3389/fnut.2026.1912094

• Review

  Published 7 October 2026

  GLP-1 receptor agonists as potential disease-modifying agents in Parkinson’s and Alzheimer’s disease: mechanisms, clinical trial evidence, and the neuroprotection horizon

  Mohamed Alsharif · Omran Shrebaty · Mohammad Ammar Aloudah · Mayar Alqahtani · Raghad Saud Aloubili · Marafi Jammaa Ahmed · Bana Albani · Ahmad El Bana

  Frontiers in Aging Neuroscience

  doi 10.3389/fnagi.2026.1969490

• Original Research

  Published 7 October 2026

  Network analysis reveals that total hip arthroplasty restores shared segmental motion before segmental differentiation

  Madhur Mangalam · Brian Schlattmann · Christopher Deans · Elizabeth Wellsandt

  Frontiers in Network Physiology

  doi 10.3389/fnetp.2026.1916345

• Clinical Trial

  Published 6 October 2026

  An intravaginal ring for HIV pre-exposure prophylaxis: assessment of safety and pharmacokinetics in a randomized, placebo-controlled clinical trial

  Kathleen L. Vincent · John A. Moss · Mark A. Marzinke · Richard B. Pyles · Lauren Dawson · Trevelyn J. Olive · Irina Butkyavichene · Amalia E. Castonguay · John M. Cortez · Mariana Remedios-Chan · Patricia Galvan · Sofia Rivera · Simon Webster · Manjula Gunawardana · Amy P. Adler · Christina M. Ramirez · Hans M. L. Spiegel · Craig W. Hendrix · Peter A. Anton · Marc M. Baum

  Frontiers in Cellular and Infection Microbiology

  doi 10.3389/fcimb.2026.1955105

• Systematic Review

  Published 5 October 2026

  Fetal and neonatal outcomes of pregnancies complicated by maternal sleep-disordered breathing: a systematic review

  Mayu Niisaka · Jun Hosomichi · Sakina Mitsuishi · Shiho Kino · Takashi Ono

  Frontiers in Physiology

  doi 10.3389/fphys.2026.1775697

• Original Research

  Published 2 October 2026

  Effects of individualized blood flow restriction during brief twice-weekly low-load cycling on mobility and muscle function in adults older than 70 years

  Alexander Franz · Simon Schroeder · Sanghyeon Ji · Frank Sebastian Fröschen · Ralf-Joachim Schulz · Patrick Wahl

  Frontiers in Sports and Active Living

  doi 10.3389/fspor.2026.1933001

• Clinical Trial

  Published 2 October 2026

  Impact of contraceptive initiation on the cervicovaginal mucosa: results from the UMPALA multicentre, partially randomized patient-preference interventional trial

  Betty Njoroge · Nelly Mugo · Carolina Herrera · Karen Dominguez · Louise A. Ouattara · Nazita Yousefieh · Neelima Chandra · Agnieszka Kurczewska · Stephanie Nartey · Julie Lewis · Andrea R. Thurman · Matilda Saina · Raina N. Fichorova · Jacques Ravel · Reem Sharaf Alddin · Nicola Richardson-Harman · Kenneth Ngure · Gustavo F. Doncel

  Frontiers in Reproductive Health

  doi 10.3389/frph.2026.1882772

• Systematic Review

  Published 1 October 2026

  Circulating and cerebrospinal fluid soluble TREM2 levels and risk of perioperative neurocognitive disorders in surgical patients: a systematic review and meta-analysis

  Haotian Wu · Yujie Wang · Zhifeng Gao · Huan Zhang

  Frontiers in Aging Neuroscience

  doi 10.3389/fnagi.2026.1899745

• Original Research

  Published 1 October 2026

  Preoperative staging of gastric cancer: a prospective comparison of gastric filling ultrasonography and enhanced CT with implications for surgical decision-making

  Xinxin Qin · Junmei Zhao · Litao Ge · Song Wu · Xiaofeng Sun · Wei Li

  Frontiers in Surgery

  doi 10.3389/fsurg.2026.1925096

• Original Research

  Published 30 September 2026

  Behavioral markers of motor reserve: stability, lateralization, and consistency

  David Vagni · Emanuela Principe · Melissa Pirrotta · Laura Catalano · Chiara Milasi · Morena De Francesco · Andreina Giustiniani · Chiara Arena · Francesco Scarfone · Angelo Quartarone · Domenico Bosco · Giovanni Pioggia · Antonio Cerasa

  Frontiers in Aging Neuroscience

  doi 10.3389/fnagi.2026.1921302

• Clinical Trial

  Published 30 September 2026

  Exploring adapted water polo: a feasibility study on improving psychosocial recovery in women post-breast cancer treatment

  S. Cuvelier · C. Goetgheluck-Villaron · C. Zemmour · S. Bernasconi · A. Tallet · A. Arthur · P. Dantin · P. Viens · M. Cohen · S. Calvin

  Frontiers in Sports and Active Living

  doi 10.3389/fspor.2026.1910555

• Original Research

  Published 29 September 2026

  NMA plus antitumor therapy versus antitumor therapy alone in patients with BCLC stage B or C hepatocellular carcinoma and pre-cachexia or cachexia: protocol for a prospective, multicenter, randomized, open-label phase II trial

  Ruihong Dai · Facheng Lu · Weibing Leng · Qing He · Wenhao Guo · Tao Hai · Chang Liu

  Frontiers in Gastroenterology

  doi 10.3389/fgstr.2026.1926294

• Review

  Published 28 September 2026

  Cancer prevention and interception studies registered in ClinicalTrials.gov: a landscape analysis of trial characteristics and reporting gaps

  Martha Fors · Paloma González · Ariel Torres · Lizbeth Silva-Guayasamín · Christian Silva-Sarabia

  Frontiers in Epidemiology

  doi 10.3389/fepid.2026.1943268

• Study Protocol

  Published 28 September 2026

  Randomized non-inferiority within-patient trial of density gradient processing of sequential ejaculates versus centrifugation-free sperm separation device for ICSI in men with elevated sperm DNA fragmentation- study protocol

  Vipin Chandra · Shashank Sanagoudar · Jayesh Shinde · Naval Shah · Isha Suwalka · Sandro C. Esteves

  Frontiers in Urology

  doi 10.3389/fruro.2026.1913330

• Original Research

  Published 23 September 2026

  I need it. Without it, I wouldn't have gone, and I do want to go: patient perspectives on the acceptability and appropriateness of two patient-centered interventions to improve adherence to annual lung cancer screening

  Lorella Palazzo · Casey Luce · Anjali Vasavada · Kayne Mettert · Hongyuan Gao · James D. Ralston · Nadejda Bezman · Beverly B. Green · Kristine Rogers · Melissa L. Anderson · Yu-Ru Su · Matthew Triplette · Lisa Carter-Bawa · Karen J. Wernli

  Frontiers in Health Services

  doi 10.3389/frhs.2026.1810956

• Original Research

  Published 22 September 2026

  Effectiveness of tailored individual follow-up vs. standard one-day group course on health-related quality of life in patients with post COVID-19 condition: a randomized controlled trial

  Marte Wilson · Henriette Michalsen · Audny Anke · Synne G. Pedersen · Marina Espinasse · Nina Langeland · Rebecca J. Cox · Pål Aukrust · Tuva B. Dahl · Axel Sandvig · Maja Wilhelmsen

  Frontiers in Rehabilitation Sciences

  doi 10.3389/fresc.2026.1927300

• Clinical Trial

  Published 21 September 2026

  CaroRite™ for improving skin health and the visible signs of aging - a randomised, double-blind, placebo-controlled trial

  Amanda Rao · Janice Pellow · David Briskey

  Frontiers in Aging

  doi 10.3389/fragi.2026.1858090

• Original Research

  Published 18 September 2026

  Beyond renal support: biological modulation across pathophysiological domains during continuous renal replacement therapy — a randomized pilot study

  Fernando Sánchez-Morán · Salvador Pérez · Juan Sastre-Belloch · María Lidón Mateu-Campos

  Frontiers in Nephrology

  doi 10.3389/fneph.2026.1932419

• Clinical Trial

  Published 16 September 2026

  Perioperative challenges: does smoking compromise high-flow nasal oxygen efficacy in obese Men? A randomised controlled trial

  Huabing Wang · Chunyan Zhang · Lu Li · Yu Tian · Chao Chen

  Frontiers in Anesthesiology

  doi 10.3389/fanes.2026.1915310

• Original Research

  Published 16 September 2026

  Effects of an outpatient pulmonary rehabilitation program on exercise capacity, muscle fatigue, dyspnea, and functional status in post-COVID-19 patients: non-randomized clinical trial

  Miriã C. Oliveira · Paolo Capodaglio · Heren N. C. Paixão · Adriano L. Fonseca · Larissa R. Alves · Jairo B. S. Ribeiro Júnior · Rodrigo F. Oliveira · Tiago V. Fernandes · Daniel G. Marconi · Rodrigo A. C. Andraus · Deise A. A. P. Oliveira · Claudia S. Oliveira · Carlos H. M. Silva · Orlando A. Guedes · Wilson R. Freitas Júnior · Luis V. F. Oliveira

  Frontiers in Rehabilitation Sciences

  doi 10.3389/fresc.2026.1921478

• Brief Research Report

  Published 15 September 2026

  Serum BDNF in subacute stroke: effects of a four-week aerobic exercise intervention in the PHYS-STROKE trial

  Torsten Rackoll · Lea Doppelbauer · Konrad Neumann · Alexander Heinrich Nave

  Frontiers in Stroke

  doi 10.3389/fstro.2026.1897859

• Original Research

  Published 11 September 2026

  The value of performance-based tests in the assessment of patients with fibromyalgia: a construct validity and comprehensiveness analysis of a standardized test battery

  José Luis Socorro-Cumplido · Joaquim Chaler · Miriam Almirall · Judith Sánchez-Raya · Josep Blanch-Rubió · Maria José Castro · Maria Giné-Garriga · Patricia Launois · Tamara Rodríguez-Araya · Anna Arias Gassol · Geert Crombez · Raimon Milà Villarroel · Blanca Roman-Viñas

  Frontiers in Rehabilitation Sciences

  doi 10.3389/fresc.2026.1947752

• Clinical Trial

  Published 11 September 2026

  Feasibility and safety of multi-field functional electrical stimulation for distal upper-limb rehabilitation after subacute stroke: a randomised controlled feasibility trial

  Silvia Guillén-Climent · Pablo Casado-Adam · Manuela Mejías-Ruiz · Aitor Martín-Odriozola · Cristina Rodríguez-de-Pablo · Inmaculada Salcedo-Leal · Esmeralda Sillero-Ruz · María Dolores Morente-Navajas · Manuel Flores-Lara · José Peña-Amaro · Fernando Jesús Mayordomo-Riera

  Frontiers in Rehabilitation Sciences

  doi 10.3389/fresc.2026.1920617

• Study Protocol

  Published 10 September 2026

  Impact of ethanol sclerotherapy on pelvic pain and quality of life in patients with endometriomas (ESCOMA study): protocol for a randomised clinical trial

  Rodrigo Guevara-Peralta · Jose Manuel Martinez-Garcia · Carlos Ortega-Expósito · Maria Jesús Pla-Farnós · Carlos Yeste · Judit Peñafiel · Júlia Guevara-Figueras · Jordi Ponce · Amparo García-Tejedor

  Frontiers in Reproductive Health

  doi 10.3389/frph.2026.1911200

• Clinical Trial

  Published 9 September 2026

  Synergy-based Functional Electrical Stimulation for gait rehabilitation in chronic stroke: a pilot study

  Jackson Taylor Levine · Xin S. Yu · Rebecca Muñoz · Alaina Fiorenza · Irina Djuraskovic · J. D. Peiffer · Emilia Ambrosini · Simona Ferrante · Elliot J. Roth · Jozsef Laczko · Ronald James Cotton · Alessandra Pedrocchi · Jose L. Pons

  Frontiers in Rehabilitation Sciences

  doi 10.3389/fresc.2026.1847719

• Study Protocol

  Published 28 August 2026

  BRIDGES: a patient-centered, community-informed HIV doula program that supports infant feeding choice among Hispanic and Caribbean families: a study protocol

  Rachel Mpanu-Mpanu · Melanie Francis · Kassandra N. Garcia · Lunthita M. Duthely

  Frontiers in Reproductive Health

  doi 10.3389/frph.2026.1896729

• Review

  Published 27 August 2026

  Where healthcare systems fall short in long-term ostomy care: implications for quality of life, healthcare utilization, and sustainable care pathways

  Judith A. Hargreaves · Diego Schaps · Beata Buchelt

  Frontiers in Gastroenterology

  doi 10.3389/fgstr.2026.1920507

• Original Research

  Published 19 August 2026

  Exploring nightly variability in sleep apnea and changes in severity classification with multi night sleep testing in a population based cohort of young children

  Solveig Magnusdottir · Ingibjorg Ingolfsdottir · Hugi Hilmisson · Laufey Hrolfsdottir · Magnus Birkisson · Erla Hallgrimsdottir · Groa Johannesdottir · Hannes Petersen

  Frontiers in Sleep

  doi 10.3389/frsle.2026.1903809

• Methods

  Published 19 August 2026

  Open and closed loop differential target multiplexed spinal cord stimulation in patients with persistent spinal pain syndrome type II: protocol for a one year European multicenter cohort study (ENDLESS)

  Lisa Goudman · Kliment Gatzinsky · Vivek Mehta · Kavita Poply · Ashish Gulve · Iris Smet · Paul Murphy · Dirk Rasche · Georgios Matis · Jan Willem Kallewaard · José Manuel Trinidad · Pasquale De Negri · Philippe Rigoard · ENDLESS consortium · Maarten Moens

  Frontiers in Pain Research

  doi 10.3389/fpain.2026.1922595

• Study Protocol

  Published 7 August 2026

  Youth post-discharge recovery and family adjustment after inpatient mental health treatment – study protocol for the longitudinal mixed-methods ReCoVer study

  Amos-Silvio Erik Friedrich · Martina Zemp

  Frontiers in Child and Adolescent Psychiatry

  doi 10.3389/frcha.2026.1605414

• Clinical Trial

  Published 23 July 2026

  Comparing visual outcomes in matched patients receiving a low cylinder power toric IOL or a non-toric IOL

  Kjell G. Gundersen · Richard Potvin · Steffen A. Østenstad

  Frontiers in Ophthalmology

  doi 10.3389/fopht.2026.1755069

• Original Research

  Published 21 July 2026

  Assessment of compliance and satisfaction with a self-adjusting bimodal neuromodulation device and virtual follow-up visits used for tinnitus

  Grace Conchas · Yezihalem Mesfin · Yuan He · Abigail P. Heiller · Hubert H. Lim · Meredith E. Adams · Peggy Nelson

  Frontiers in Audiology and Otology

  doi 10.3389/fauot.2026.1789957

• Clinical Trial

  Published 17 July 2026

  Long-term Impact of Intravitreal Injections on the ocular surface; a 2-year follow-up study

  Agni Malmin · Markus Vicente Tørud Olsen · Vilde Marie Thomseth · Inga-Britt Kjellevold Haugen · Tor Paaske Utheim · Vegard Asgeir Forsaa

  Frontiers in Ophthalmology

  doi 10.3389/fopht.2026.1829818

• Original Research

  Published 14 July 2026

  Impaired left atrial strain is associated with acute ischemic stroke in patients without atrial fibrillation

  Robert Trueick · Jonathan Shpigelman · Omar Dabash · John McCallig · Muhammad Ahmad Ashfaque · Muneeb Quidwai · Lisa Donaghy · Patricia Guilfoyle · Lavanya Saiva · James O'Neill · Michael J. Daly

  Frontiers in Stroke

  doi 10.3389/fstro.2026.1838151

• Systematic Review

  Published 9 July 2026

  Comparative efficacy of subsequent-line therapies for advanced triple-negative breast cancer: a bayesian network meta-analysis

  Zheng Xu · Linxian Ding · Tai Zhao · Zhoumin Xu

  Oncology Reviews

  doi 10.3389/or.2026.1834466

• Original Research

  Published 7 July 2026

  Age, race, and education as moderators of post-stroke cognitive decline following dental care

  Michael H. Parrish · Leonardo Bonilha · Karly Pikel · Caitlin Scott · Stefanie Wood · Haley N. VerKuilen · Souvik Sen

  Frontiers in Stroke

  doi 10.3389/fstro.2026.1807730

• Brief Research Report

  Published 29 June 2026

  Acute cerebrovascular disease in the Philippine Neurological Association One Database (PNA1DB)—patient profiles and disparities between public and private hospitals

  Robert N. Gan · Jose Leonard R. Pascual V · Maria Epifania V. Collantes · John Harold B. Hiyadan · Dan Neftalie A. Juangco · Ma. Cristina Z. Macrohon-Valdez · Cyrus G. Escabillas · Christian Oliver C. Co · Gemmalynn B. Sarapuddin · Maria Teresa A. Cañete · Raquel M. Alvarez · Belinda L. Mesina-Nepomuceno · Johnny K. Lokin · Marie Charmaine Sy Lukban · Rosalina E. Picar

  Frontiers in Stroke

  doi 10.3389/fstro.2026.1835562

• Original Research

  Published 17 June 2026

  Good nights sleep program: design and preliminary findings from a randomized clinical trial to improve child and parent sleep in low-income families

  Brian T. Gillis · Ben Hinnant · Olivia Martín-Piñón · Elise L. Neuhoff

  Frontiers in Sleep

  doi 10.3389/frsle.2026.1764378