ReviewPublished 7 October 2026The 19S proteasome as a therapeutic target in hematologic malignanciesIdaly M. Olivas · Mayra A. Gonzalez-Henry · Saeedeh Darvishi · Evelyn M. Esparza · Anna M. EiringFrontiers in Cell and Developmental Biologydoi 10.3389/fcell.2026.1918833
Mini ReviewPublished 3 September 2026Beyond RNA/DNA: exploring the emerging role of Poly(ADP-ribose): structure, function, and condensate formationLipika Baidya · Hung T. NguyenFrontiers in Biophysicsdoi 10.3389/frbis.2026.1930609
ReviewPublished 17 August 2026Mesenchymal stem cell senescence as a potency brake: causes, consequences, and curesSen Zhou · Yu Xie · Yanjie Guo · Yufu Zhang · Yusi LiuFrontiers in Agingdoi 10.3389/fragi.2026.1929624
Original ResearchPublished 7 August 2026Functional phosphoproteomic analysis of SMG1 in nonsense-mediated mRNA decay and DNA damage repair in cancerApoorva K. A. Pai · Leona Dcunha · Athira Perunelly Gopalakrishnan · Samseera Ummar · Athira C. Rajeev · Rajesh RajuFrontiers in Systems Biologydoi 10.3389/fsysb.2026.1788470
Original ResearchPublished 20 February 2026Roscovitine derivative optimization via molecular dynamics reveals potent and selective CDK5 bindersLorenzo Botta · Giovanni Carotenuto · Manuel Arcieri · Elena Di Nisio · Valerio Perticaroli · Tiziana Castrignanò · Raffaele Saladino · Rodolfo NegriFrontiers in Chemical Biologydoi 10.3389/fchbi.2026.1741100
Cell DeathPublished 3 September 2025C/EBPβ deficiency enhances keratinocyte apoptosis after UVB-induced DNA damage via regulation of the type I IFN and TNF responsesEmma E. Tobin · Ayushma Sharma · Samantha T. Kros · Dereje D. Jima · Sophia C. Gray · Jonathan R. HallFrontiers in Cell Deathdoi 10.3389/fceld.2025.1658598
