Articles

Showing 49 articles

• Original Research

  Published 12 October 2026

  Plasmodium falciparum putative Hsp90 functionally complements yeast Hsp90 and is inhibited in an isoform-specific manner

  Shradha Ravindra Khamitkar · Monalisa Bag · Vaibhav R. Kini · Mansi Singh · Badal Kumar Sethi · Sunanda Bhattacharyya

  Frontiers in Parasitology

  doi 10.3389/fpara.2026.1944050

• Original Research

  Published 12 October 2026

  Interpreting imported malaria genomes: population-genomic sensitivity analyses of West Africa-associated Plasmodium falciparum isolates detected in China

  Xuli Du · Ye Hu · Haimo Shen · Mengyu Li · Yuxin Wang · Yanli Bai · Shenbo Chen · Yanting Fan

  Frontiers in Cellular and Infection Microbiology

  doi 10.3389/fcimb.2026.1950822

• Systematic Review

  Published 8 October 2026

  Antimalarial and antiplasmodial compounds (2024–2026): a systematic review of synthetic, semi-synthetic, and natural agents

  Bertin Mikolo · Gelase Fredy Nsonde Ntandou · Hermeline Tabuna Nee Ntalani

  Frontiers in Tropical Diseases

  doi 10.3389/fitd.2026.1944733

• Original Research

  Published 30 September 2026

  Protoberberine alkaloids berberine and palmatine employ Pf Pgh-1 transporter to enter the digestive vacuole and kill the malaria parasite by inhibiting heme biocrystallization

  Nekpen Erhunse · Prachi Tomar · Dinkar Sahal · Agam Prasad Singh

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1949463

• Original Research

  Published 18 September 2026

  Low prevalence of Plasmodium falciparum pfhrp 2 and pfhrp 3 gene deletions in archived samples collected before and after nationwide malaria-RDT rollout in Kenya

  Martha N. Kivecu · Victor Mobegi · Cavin Mgawe · Brenda M. Kania · Gladys C. Chemwor · Raphael O. Okoth · Edwin W. Mwakio · George Obiero · Jennifer M. Mutisya · Jackline A. Juma · Agnes C. Cheruiyot · Benjamin H. Opot · Amanda L. Roth · Bernhards R. Ogutu · Dennis W. Juma · Lynette Isabella Ochola-Oyier · Ben Andagalu · Hoseah M. Akala

  Frontiers in Epidemiology

  doi 10.3389/fepid.2026.1817539

• Original Research

  Published 15 September 2026

  Inhibition of Plasmodium DNA double strand repair by the combined action of 17-AAG and ML216

  Km Tanishka · Wahida Tabassum · Deepak Kumar Rout · Maria Mukherjee · Mrinal Kanti Bhattacharyya

  Frontiers in Parasitology

  doi 10.3389/fpara.2026.1896831

• Review

  Published 14 September 2026

  Mechanisms of insecticide resistance in mosquitoes and their implications for disease control

  Rakesh Padhan · Jatin Kumar · Bharti Goyal · Ram Das · Vikas Kumar · Soumyaranjan Pradhan · Kailash C. Pandey · Tarun Kumar Vats · Bhuvan Dixit

  Frontiers in Malaria

  doi 10.3389/fmala.2026.1890327

• Review

  Published 11 September 2026

  AI and silkworm biomanufacturing: a new paradigm for malaria therapeutics access

  Anthony Pilorget · Sospeter Ngoci Njeru · Damaris Matoke-Muhia · Christophe Loizel

  Frontiers in Malaria

  doi 10.3389/fmala.2026.1909034

• Original Research

  Published 11 September 2026

  Probing the activity of BM212, an antimycobacterial, and its derivatives against multiple life cycle stages of Plasmodium falciparum

  Benedetta Salvucci · Mariëtte van der Watt · Chiara Tammaro · Michela Guida · Lucrezia Pantaleo · Janette Reader · Tayla Rabie · Sizwe Tshabalala · Mariska Naude · Natanya Venter · Tyrick Welcome · Erica Erlank · Lizette L. Koekemoer · Mariangela Biava · Lyn-Marié Birkholtz · Giovanna Poce

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1919483

• Review

  Published 9 September 2026

  Advanced nanomaterials for malaria theranostics

  Suresh Thangudu · Karthik Nuthalapati · Chiranjib Patra · Ganesh Kamble · Chiranjeevi Korupalli · Ganesh Gollavelli

  Frontiers in Malaria

  doi 10.3389/fmala.2026.1925644

• Review

  Published 26 August 2026

  Molecular mechanisms underlying drug resistance in protozoan parasites: emerging mechanisms and therapeutic perspectives

  Kavithma Uduwela · Koshila Ranasinghe

  Frontiers in Parasitology

  doi 10.3389/fpara.2026.1934996

• Perspective

  Published 21 August 2026

  Holding the line against artemisinin partial resistance in Africa: the case for preemptive treatment policy

  Shyamkumar Sriram

  Frontiers in Malaria

  doi 10.3389/fmala.2026.1916099

• Original Research

  Published 21 August 2026

  Retrospective study of association between Plasmodium falciparum malaria density and platelet count at Presbyterian Hospital, Agogo

  Theophilus Arthur-Gyimah · Doreen Asantewa Abeasi · Frank Bediako Agyei · Stephen Owusu Apau · Josephine Yeboah Agyapong

  Frontiers in Malaria

  doi 10.3389/fmala.2026.1875477

• Brief Research Report

  Published 17 August 2026

  Navigating imaging artifacts: challenges with visualizing intrinsically fluorescent antimalarials

  Emily K. Bremers · David Anaguano · Paul R. Carlier · Vasant Muralidharan · Maria Belen Cassera

  Frontiers in Parasitology

  doi 10.3389/fpara.2026.1919904

• Mini Review

  Published 17 August 2026

  Salivary gland microbiome of Anopheles gambiae: a mini-review of acquisition, composition, and functional significance

  Celestina O. Olafusi · Israel S. Afolabi · Olubanke O. Ogunlana

  Frontiers in Insect Science

  doi 10.3389/finsc.2026.1911294

• Editorial

  Published 13 August 2026

  Editorial: Global perspectives on severe vivax malaria: incidence, outcomes, and biological mechanisms

  Dhanpat Kumar Kochar

  Frontiers in Malaria

  doi 10.3389/fmala.2026.1923808

• Original Research

  Published 13 August 2026

  Ex vivo maturation of the malaria parasite egress protease SERA6 aids pathway dissection and inhibitor development

  Chrislaine Withers-Martinez · Zahie Taha · Christine R. Collins · Fiona Hackett · Michele S.Y. Tan · Christelle Soudy · Dhira Joshi · Joanna Redmond · Benedict Davies · Sarah Maslen · Mark Skehel · Roger George · Svend Kjaer · Michael J. Blackman

  Frontiers in Parasitology

  doi 10.3389/fpara.2026.1823181

• Original Research

  Published 10 August 2026

  Investigating angiotensin II concentration in modulating Plasmodium falciparum infection and angiotensin receptor activation

  Auley De · Aparna Tiwari · Medha Agarwal · Veena Pande · Abhinav Sinha

  Frontiers in Parasitology

  doi 10.3389/fpara.2026.1852476

• Original Research

  Published 8 July 2026

  Chemical profiling and pharmacological potential of myxobacteria isolated from Brazilian mangrove sediments

  Renan S. Oliveira · Luís G. F. Feitosa · Caio S. Moura · Elthon G. Ferreira · Andrezza J. Gozzo · Letícia V. Costa-Lotufo · Norberto P. Lopes · Anna C. C. Aguiar · Marcelo J. P. Ferreira · Paula C. Jimenez

  Frontiers in Natural Products

  doi 10.3389/fntpr.2026.1816108

• Original Research

  Published 10 June 2026

  Different agroecosystems have similar Anopheles – Microsporidia MB infection dynamics in the Ahero region of Western Kenya: implications for symbiont control strategies

  Joseph Gichuhi · Tullu Bukhari · Thomas Ogao Onchuru · Oscar Mbare · Erick Odoyo · Jeremy Keith Herren

  Frontiers in Malaria

  doi 10.3389/fmala.2026.1794884

• Original Research

  Published 3 June 2026

  Antiparasitic triterpenic ester and ursolic acid lipid nanocapsule design, cytotoxicity, and permeability evaluation for oral delivery

  Laura Schioppa · Cecilia Bohns Michalowski · Lucia Mamede · Romano Terrasi · Marie-France Hérent · Giulio G. Muccioli · Raphaël Frédérick · Michel Frederich · Ana Beloqui · Joelle Quetin-Leclercq

  Frontiers in Drug Delivery

  doi 10.3389/fddev.2026.1846904

• Brief Research Report

  Published 7 April 2026

  Haplotype diversity of Plasmodium falciparum circumsporozoite protein prior to malaria vaccine implementation in Kaelé Health District, Cameroon, 2022–2023

  Innocent M. Ali · Brenda Vasquez Martinez · Valery P. K. Tchuenkam · Jacob M. Sadler · Catherine C. Gorman · Sandrine E. Nsango · Voundi Voundi Junior · Joel Marcellin Ateba · Grace Yimga Wanda · Jeffrey A. Bailey · Rhoel R. Dinglasan · Jessica T. Lin · Jonathan J. Juliano

  Frontiers in Parasitology

  doi 10.3389/fpara.2026.1749169

• Original Research

  Published 31 March 2026

  Non-linear effects of parasite density on symptom burden and hematologic indices in pediatric Plasmodium falciparum malaria

  Olugbenga Ayodeji Mokuolu · Mohammed Baba Abdulkadir · George Oche Ambrose · Joseph Oladele Ole · Toluwani Mokuolu · Lukman Lawal · Adegboyega Joshua Agboola · Kafayat Oluwafunke Suleiman · Selimat Ibrahim · Samuel Whyte Jegede · Alexander Idu Entonu · Abdur-Rasheed Opeyemi Makinde · Okikiola Sobuur Fagbolade · Aroniyo Opeyemi Omolehin · Fuhad Damilola Azeez · Daniel Oluwagbenga Abegunde · Rahmatullah Ahuoiza Ogirima · Kolawole Temidayo Ajayi · Oluwaseun Oluwafemi Ayorinde · Akinmeji Kateanah Ibukun

  Frontiers in Malaria

  doi 10.3389/fmala.2026.1751312

• Original Research

  Published 27 November 2025

  Prevalence and Plasmodium species distribution of asymptomatic malaria parasitemia among blood donors at the Lilongwe blood transfusion center

  Collins Bowa · Ndagha Kalonga · Benjamin Mbonshi · Lungowe Sitali · Joseph Simwela · Evarister Kudowa · Amazing-Grace Tepeka

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1687355

• Original Research

  Published 11 November 2025

  Genomic dynamics of clinical Plasmodium vivax: comparative genomic hybridization in severe malaria cases

  Sampreeti Tahbildar · Pon Arunachalam Boopathi · Sanjay Kumar Kochar · Dhanpat Kumar Kochar · Mohamed Aiyaz · Raja C. Mugasimangalam · Sudha N. Rao · Ashis Das

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1667330

• Parasitology

  Published 4 November 2025

  Genetic polymorphism of Plasmodium falciparum circumsporozoite protein in Kigali, Rwanda

  Sandra Noukimi Fankem · Jean-Bosco Mbonimpa · Edgar Mutebwa Kalimba · Mariama Telly Diallo · Jacob Souopgui

  Frontiers in Parasitology

  doi 10.3389/fpara.2025.1679131

• Malaria

  Published 3 November 2025

  Editorial: Women in malaria research

  Alena Pance · Elena Gómez-Díaz · Sarah Reece

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1725748

• Malaria

  Published 3 October 2025

  Efficacy of low-dose primaquine plus artemether-lumefantrine or dihydroartemisinin-piperaquine for radical cure of Plasmodium vivax in the Solomon Islands: a randomised clinical trial

  Robert James · Thomas Obadia · Lyndes Wini · Albino Bobogare · Sarah Charnaud · Shazia Ruybal-Pesántez · Caitlin Bourke · Jacob E. Munro · Brioni R. Moore · Madhu Page-Sharp · Laurens Manning · Urijah Liligeto · Sophie G. Zaloumis · J. Kevin Baird · Harin Karunajeewa · Ivo Mueller

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1604498

• Malaria

  Published 17 September 2025

  Specificity and kinetics of human candidate cerebral malaria biomarkers in mice

  Cláudia Gomes · Lizeth Chicas · Kelly A. Crotty · Isaac Salzano · Davidi Tawfiles · Ana Rodriguez

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1553466

• Malaria

  Published 16 September 2025

  Molecular polymorphism of Plasmodium vivax Duffy binding protein domain II from Nicaragua, and global diversity patterns

  René Ortega-Monroy · Hugo A. Tomasini-Ovilla · Frida Santillan-Valenzuela · Alberto Montoya · Lilia Gonzalez-Ceron

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1620450

• Parasitology

  Published 4 August 2025

  Physiological, environmental, and life-history drivers of haemosporidian infections in non-passerine birds from a rehabilitation center

  Lis Marques de Carvalho e Vieira · Victor Aguiar de Souza Penha · Kevin J. McGraw · Amanda Vitória Dornelas da Silva · Erika Martins Braga

  Frontiers in Parasitology

  doi 10.3389/fpara.2025.1568852

• Parasitology

  Published 30 July 2025

  Guanine derivatives as promising candidates for the development of purine-based antimalarial drugs

  Worlanyo Tashie · Harry P. de Koning · Nancy O. Duah-Quashie · Neils B. Quashie

  Frontiers in Parasitology

  doi 10.3389/fpara.2025.1634209

• Malaria

  Published 25 July 2025

  Dynamic shift of malaria cases in northwest Ethiopia: a 10-year retrospective cohort data analysis from 2012 to 2021

  Aberham Abere · Solomon Ayalew · Bealemlay Wondale · Fentahun Tigabu · Nigus Gizachew · Takele Tesfaye · Getnet Ayalew · Banchamlak Tegegne · Mulat Yimer Melaku · Yibeltal Aschale · Adane Tilahun · Mebratu Tamir · Fentahun Megabiaw · Tegegne Eshetu · Adane Derso

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1460491

• Malaria

  Published 3 July 2025

  Impact of artemether–lumefantrine treatment, circadian rhythm, and serum replacement on the infectiousness of wild Plasmodium falciparum gametocytes to Anopheles gambiae sensu stricto mosquitoes

  Dorin Joachim Mmasi · Prisca Kweyamba · Fatuma Matwewe · Masudi Suleiman Maasayi · Nolvin J. Mvungi · Ummi Abdul Kibondo · Tibebu Habtewold · Jennifer C. Stevenson · Lorenz Martin Hofer · Sarah Jane Moore · Mgeni M. Tambwe

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1609614

• Malaria

  Published 27 June 2025

  Prevalence of Plasmodium falciparum infection in school-aged children in urban and peri-urban schools of Bamako, Mali

  Mahamoudou Toure · Fousseyni Kane · Daouda Sanogo · Soumba Keita · Bourama Keita · Abdoul Zamilou Aro · Moussa Keita · Drissa Konate · Sory I. Diawara · Alpha S. Yaro · Aissata Kone · Mahamadou Magassa · Salim Kante · Cheick O. Tangara · Karamoko Tangara · Hamady Coulibaly · Bourema Cisse · Sidibe M’Baye Thiam · Amadou S. Traore · Jeffrey G. Shaffer · Nafomon Sogoba · Mahamadou Diakite · Seydou Doumbia

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1596496

• Malaria

  Published 25 June 2025

  Targeting mucosal immunity in malaria control: the underexplored role of IgA

  Haruna Muwonge · Isaac Ssewanyana · Adoke Yeka · Pauline Byakika-Kibwika

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1557371

• Malaria

  Published 15 May 2025

  Mosquito vector diversity and malaria transmission

  Brandy St. Laurent

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1600850

• RNA Research

  Published 15 April 2025

  Identification of long noncoding RNAs (lncRNAs) and co-transcriptional analysis of mRNAs and lncRNAs in transcriptomes of Anopheles gambiae

  Jiannong Xu · Kai Hu · Michelle M. Riehle · Vedbar S. Khadka

  Frontiers in RNA Research

  doi 10.3389/frnar.2025.1555885

• Malaria

  Published 9 April 2025

  Quantification of Plasmodium falciparum: validation of quantitative polymerase chain reaction assays for detection of parasites in controlled human malaria infection studies

  Elizabeth Kibwana · Domtila Kimani · Nick J. Edwards · Kelvias Keter · Agnes Mutiso · Lydia Nyamako · Rose Gatheru · Adrian V. S. Hill · Philip Bejon · Katie J. Ewer · Melissa C. Kapulu

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1497613

• Malaria

  Published 28 March 2025

  Primaquine-induced hemoglobinuria: a case report of a G6PD deficient malaria patient with Mahidol trait from Bandarban, Bangladesh

  Md Fahad Zamil · Ching Swe Phru · Anamul Hasan · Afrida Tabassum Trina · Mohammad Shahbaz · Shahrear Tanvir Ahmed · Mohammad Sharif Hossain · Mohammad Shafiul Alam

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1544378

• Malaria

  Published 24 February 2025

  Allelic variations in putative antimalarial drug resistance and vaccine candidate genes among Plasmodium vivax reference genomes

  Suman Tamang · Aditi Arya · Vineeta Singh

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1530088

• Malaria

  Published 31 January 2025

  High rate of false positive malaria rapid diagnostic tests in a district hospital in Uganda

  Susanne E. Mortazavi · Allan Lugaajju · Anna-Clara Ivarsson · Sara Karlsson Söbirk · Hans Norrgren · Kristina E. M. Persson

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1545825

• Malaria

  Published 30 January 2025

  Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives

  Dagmawi Woldesenbet · Yalewayker Tegegne · Abdulhakim Mussema · Elias Tamene · Kemal Mohamed · Wagaw Abebe · Melese Mekuria · Kasahun Bogale · Habtamu Geremew · Mufta Muzemil Shifa · Mulugeta Aemero Tegegne

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1492444

• Malaria

  Published 28 January 2025

  Parasitological and clinical correlates of Plasmodium–Schistosoma mansoni co-infection and its determinants among Plasmodium- infected patients in the Wolaita Zone, South Ethiopia regional state

  Kemal Mohamed · Tariku Belay · Ahmed Zeynudin

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1519846

• Malaria

  Published 14 January 2025

  Molecular identification of pfcytb, pfdhfr, and pvmrp1 mutations in imported malaria cases in Chile

  Alan Oyarce · Lizbeth Huaccha · Esteban M. Cordero · Bárbara Parra · Jorge Fernández · Mario E. Soto-Marchant · Natalia T. Santis-Alay · María Isabel Jercic

  Frontiers in Malaria

  doi 10.3389/fmala.2024.1516733

• Malaria

  Published 12 December 2024

  Burden and clinical characteristics of recurrent Plasmodium vivax infections, and impact of primaquine for radical cure: a systematic scoping review in India

  Loick Pradel Kojom Foko · Vineeta Singh

  Frontiers in Malaria

  doi 10.3389/fmala.2024.1511568

• Malaria

  Published 28 November 2024

  Proteomic profile of plasma-derived extracellular vesicles from Colombian pregnant women with Plasmodium -soil transmitted helminths coinfection

  Jahnnyer A. Martínez-Moreno · Alberto Ayllon-Hermida · Berta Barnadas-Carceller · Carmen Fernández-Becerra · Hernando A. del Portillo · Jaime Carmona-Fonseca · Eliana M. Arango-Flórez

  Frontiers in Malaria

  doi 10.3389/fmala.2024.1484359

• Malaria

  Published 1 November 2024

  Plasticity in malaria parasite development: mosquito resources influence vector-to-host transmission potential

  Catherine E. Oke · Aidan J. O’Donnell · Petra Schneider · Sarah E. Reece

  Frontiers in Malaria

  doi 10.3389/fmala.2024.1481816