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Original Research
Published 20 August 2026
New mechanistic insight into SARM1 activation: TRIM32-mediated ubiquitination is a key lever that actuates SARM1’s catalytic action, leading to axon degeneration and cell death
Hitoshi Murata · Nahoko Tomonobu · Ken-ichi Yamamoto · Rie Kinoshita · Masakiyo Sakaguchi
Frontiers in Neural Circuits
doi 10.3389/fncir.2026.1842408