Original ResearchPublished 12 October 2026Camk2d upregulation is associated with postoperative cognitive dysfunction in aged rats: pharmacological inhibition of CaMKII attenuates hippocampal neuroinflammation and neuronal apoptosisKaihua Wei · Shiwen Fan · Yujia Zhao · Xiaobin Cai · Xinlei Qin · Jingwen Zhai · Liping XieFrontiers in Aging Neurosciencedoi 10.3389/fnagi.2026.1975677
Original ResearchPublished 12 October 2026Identification and validation of biomarkers related to oxidative stress in pediatric sepsis utilizing WGCNA and multiple machine learning algorithmsYumeng Liu · Gang LuoFrontiers in Bioinformaticsdoi 10.3389/fbinf.2026.1745381
Original ResearchPublished 12 October 2026Genome-wide analysis of the GATA gene family in Castanea mollissima reveals key regulators involved in salt stress responseXiangyu Wang · Xili Liu · Jun Liu · Le Niu · Huoqiang Quan · Tong Zhang · Qinuo Li · Guoyun Zhang · Liyang YuFrontiers in Plant Sciencedoi 10.3389/fpls.2026.1907055
Original ResearchPublished 8 October 2026The role of ferro-aging genes in periodontitis: novel insights based on bioinformatics analysisPoyi Chu · Danhua Wu · Jianwen Deng · XuFeng ChenFrontiers in Cellular and Infection Microbiologydoi 10.3389/fcimb.2026.1875267
Original ResearchPublished 8 October 2026The NF-Y gene family in Rosa : evolutionary divergence across three species and potential roles in heat tolerance and secondary metabolismSainan Jiang · Jun Zhang · Jie Yang · Junlan Zhang · Wen Xing · Zeqing LiFrontiers in Plant Sciencedoi 10.3389/fpls.2026.1944775
Original ResearchPublished 8 October 2026Identification of microglia-associated hub genes and a CX3CR1/P2RY12 two-gene diagnostic model for cross-subtype epilepsy-associated cortical malformations: integrated transcriptomic analysis with external validationHongliang Zeng · Bin LiFrontiers in Neurosciencedoi 10.3389/fnins.2026.1954412
Original ResearchPublished 7 October 2026Computational identification of candidate biomarkers and compounds associated with skeletal muscle insulin sensitivity improvement mediated by physical activity: an integrative multi-omics and computational chemistry studyHong Liu · Zicheng Liang · Jun Tan · Chunyun YuanFrontiers in Bioinformaticsdoi 10.3389/fbinf.2026.1885995
Original ResearchPublished 7 October 2026Integrating transcriptomic analysis and experimental validation unravels autophagy- and lactylation-related gene signatures in acute myocardial infarctionJun Peng · Li Chen · Lizhen Liu · Xiangdong Xu · Huiwen SongFrontiers in Cardiovascular Medicinedoi 10.3389/fcvm.2026.1814910
Original ResearchPublished 30 September 2026Integrated bulk and single-cell transcriptomic analyses with experimental validation identify PLOD1 as a diagnostic biomarker and TGF-β1-responsive profibrotic mediator in dupuytren’s diseaseXianjie Lin · Mingming Wang · Yutian Lin · Yinshen Zhu · Zhijiang Ye · Haoran ChenFrontiers in Molecular Biosciencesdoi 10.3389/fmolb.2026.1924451
Original ResearchPublished 28 September 2026Integrative bioinformatics screening of a M2 macrophage-associated gene signature for osimertinib resistanceYajie Huang · Yaozhong Zhang · Jian ShiFrontiers in Geneticsdoi 10.3389/fgene.2026.1928986
Original ResearchPublished 17 September 2026Multi-cohort machine learning identifies a ferroptosis-linked prognostic signature in lung adenocarcinomaRana SalihogluFrontiers in Bioinformaticsdoi 10.3389/fbinf.2026.1921468
PhotobiologyPublished 8 July 2025Gene co-expression regulatory network analysis identifies novel regulators in light signaling pathways in ArabidopsisYanan Bai · Vinh Ngoc Pham · Enamul HuqFrontiers in Photobiologydoi 10.3389/fphbi.2025.1597248
RNA ResearchPublished 15 April 2025Identification of long noncoding RNAs (lncRNAs) and co-transcriptional analysis of mRNAs and lncRNAs in transcriptomes of Anopheles gambiaeJiannong Xu · Kai Hu · Michelle M. Riehle · Vedbar S. KhadkaFrontiers in RNA Researchdoi 10.3389/frnar.2025.1555885