Case Report
Published
Case Report: Isolated leptomeningeal relapse after systemic control in PALB2-altered pancreatic cancer
Jian Yuan · Yangxian Xu · Qihao Zhou · Guorong Yuan · Meizhen Ye
Frontiers in Medicine
doi 10.3389/fmed.2026.1927688
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 61 articles
Original Research
Published
Definitive radiotherapy versus surgery after neoadjuvant immunochemotherapy for locally advanced esophageal squamous cell carcinoma: a propensity score-matched study of efficacy and safety
Qiuying An · Yage Jia · Menglu Liu · Liyuan Fu · Jingxin Bai · Zihan Zhang · Jin Yan · Yajing Wang · Hongshan Ji · Yuhao Su · Ping Zhang · Zhiguo Zhou
Frontiers in Oncology
doi 10.3389/fonc.2026.1885302
Case Report
Published
Natural history and literature review of primary intracranial CIC-rearranged sarcomas: case report
Arissa Khan · Maryam Khan · Abigail Bowser · Sahara Cathcart · Nicole Shonka · Sean Kelly · Daniel Surdell · Breann Bowar · Danielle Cunningham · Qateeb Khan
Frontiers in Oncology
doi 10.3389/fonc.2026.1958689
Original Research
Published
Beyond binary: a novel anatomical-geographical-biological framework for perineural invasion risk stratification in oral squamous cell carcinoma – a proof-of-concept study
Shanthi Velusamy · Prajwal Dange · Karthik N. Rao · Teertha Shetty · Nethra R. · Rekha V. Kumar · Karthik S. Rishi · Aruna Korlimarla · Srinath B.S. · Sreeram M.P.
Frontiers in Oncology
doi 10.3389/fonc.2026.1897905
Clinical Trial
Published
Preliminary evaluation of ProSpare ® , a rectal obturator for prostate bed radiotherapy within the randomised multicentre POPS trial (NCT02978014)
Sarah Stewart · Karen Thomas · Jenni Parmar · Alison Claire Tree · Chris Parker · Helen McNair · Sophie Alexander · Julia Henderson · James Talbot · Christopher Scrase · Chee Goh · Reena Davda · Emma Gray · Peter Hoskin · Sarah Needleman · Jenny Nobes · Kamalram Thippu Jayaprakash · Yvonne Rimmer · Ranachandran Venkitaraman · Anna Wilkins · Vincent Khoo · Julia Murray · David Paul Dearnaley
Frontiers in Oncology
doi 10.3389/fonc.2026.1758462
Original Research
Published
A real-world nomogram integrating predictive markers for disease-free survival in postmenopausal triple-negative breast cancer receiving anthracycline/taxane-based chemotherapy
Yan Lin · Shao-hong Yu · Chai-Ming Zeng · Shuang-long Cai · Lei Han
Frontiers in Oncology
doi 10.3389/fonc.2026.1904801
Review
Published
Halogenated and metallic scaffolds as novel efflux pump inhibitors: mechanistic insight in overcoming antimicrobial and cross-domain resistance
Manaf AlMatar · Raja Lakhal · Kamaleldin H. Kamaleldin · Arig Ibrahim-Hashim
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1923157
Original Research
Published
Longitudinal peripheral immune dynamics during anti-programmed cell death 1 neoadjuvant therapy in esophageal squamous cell carcinoma
Linpeng Li · Lingwen Meng · Xinru Chen · Jiahui Li · Pengfei Li · Bo Dong · Chengjing Huang · Wei Zhou · Nuan Li · Guodong Sun · Jiawei Li · Guojie Tan · Li Jiang · Dan Tian
Frontiers in Immunology
doi 10.3389/fimmu.2026.1917487
Review
Published
Botanical polysaccharides as veterinary vaccine adjuvants: structure, receptors, and translational limits
Ran Guan · Chaoyun Yang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1982641
Original Research
Published
Baseline SII and SIRI identify immune-inflammatory susceptibility and improve risk stratification of early subclinical cardiac dysfunction during non-steroidal aromatase inhibitor therapy
Cenyu Li · Zhengyu Tao · Yihan Wu · Chen Wu · Zi Wang · Xiaoning Wang · Huijuan Dai · Meng Jiang · Jun Pu
Frontiers in Cardiovascular Medicine
doi 10.3389/fcvm.2026.1888328
Case Report
Published
Case Report: Ribociclib-associated bilateral neurotrophic keratitis requiring amniotic membrane transplantation during adjuvant treatment of early breast cancer
Danielle DeCicco · Sanjana Nethagani · Lingo Lai · Danish Safi
Frontiers in Oncology
doi 10.3389/fonc.2026.1932226
Mini Review
Published
The role of platelet-rich plasma in repeated implantation failure: a review of biological mechanisms and clinical efficacy
Fanourios Makrygiannakis · Thomas Vrekoussis · Maria Marmara · Aikaterini Berdiaki · Antonis Makrigiannakis
Frontiers in Reproductive Health
doi 10.3389/frph.2026.1907558
Original Research
Published
Design of multi-epitope vaccine based on G2c genotype PEDV antigen and its immunogenicity and protective effect in piglets
Hao Luo · Zaixing Sun · Jingxin Wang · Lin Lan · Baoning Wang
Frontiers in Veterinary Science
doi 10.3389/fvets.2026.1942409
General Commentary
Published
Commentary: Resistance breakers: a novel approach to tackle biofilm associated infections and antimicrobial resistance
Wenjie Guo · Ke Xue
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1976224
Review
Published
Advances in artificial intelligence-driven MRI research in Alzheimer’s disease
Lihua Deng · Yan Zeng · Peiling Ou · Suyi Zhou · Yu Gou · Cong Huang
Frontiers in Neurology
doi 10.3389/fneur.2026.1943265
Review
Published
Blood-based inflammatory biomarkers in ovarian cancer: addressing the challenge of early detection, metastasis, and prognostic stratification
Emmanuel Ifeanyi Obeagu
Oncology Reviews
doi 10.3389/or.2026.1914468
Original Research
Published
Design of a tetravalent dengue vaccine incorporating T-cell epitopes from NS3 and NS5 proteins and B-cell epitopes from the envelope protein using an immunoinformatics approach
Theerawat Dobutr · Pemikar Srifa · Nawamin Pinpathomrat
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1934834
Original Research
Published
Serum GDF15 as a potential biomarker for treatment response and survival in patients with resectable locally advanced gastric cancer undergoing neoadjuvant chemotherapy
Can Cao · Shunda Wang · Shikang Ding · Hongyun Huang · Tian Yu · Moxi Chen · Yibin Xie · Jianchun Yu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1948454
Review
Published
Treatment of oligometastatic disease in colorectal cancer: from molecular biology to multimodal strategies
G. Arrichiello · A. Piccolo · F. Carlino · E. Franzese · A. Ventriglia · M. Annunziata · V. Patanè · M. De Siero · M. D. Bisceglia · M. Orditura
Oncology Reviews
doi 10.3389/or.2026.1932297
Review
Published
Multimodal biomarkers for early detection and immunotherapy assessment in hepatocellular carcinoma: integrating liquid biopsy, AI-based imaging and tumor immune profiling
Yuli Zhao · Xiaolei Chen · Hanyu Zhao
Frontiers in Genetics
doi 10.3389/fgene.2026.1951687
Review
Published
Mitochondrial metabolic plasticity in cancer: hybrid bioenergetic states and translational targeting in surgical oncology
Debdeep Chattopadhyay · Ramya Lakshmi Rajendran · Nida Mubin · Durva Tendulkar · Thoudam Debraj Singh · Subhrojyoti Ghosh · Saurabh Kumar Jha · Prakash Gangadaran · Byeong-Cheol Ahn
Experimental Biology and Medicine
doi 10.3389/ebm.2026.11244
Original Research
Published
Reverse vaccinology and immunoinformatics-driven design of a multiepitope vaccine candidate against Renibacterium salmoninarum
Cristóbal Morales · Vicente Arriagada · Erick Bonilla · Bruno Prina · Esteban Godoy · Benjamín Molina-Chávez · Alberto Osorio · Emilio Gutierrez · Victor Roa · Leonardo A. Gómez · Ángel A. Oñate
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1899416
Original Research
Published
Fatty acid profile and antimicrobial activity of chloroform extracts from the red microalga Porphyridium purpureum against pathogenic intestinal bacteria
Natália Popiorek dos Santos · Rodolfo Moreira Baptista · Bruno Galler Kubelka · Marcelo Gonçalves Montes D’Oca · Jéssica Thais de Lima · Danielle Tapia Bueno · Amanda Fonseca Leitzke · Daniela Fernandes Ramos
Frontiers in Natural Products
doi 10.3389/fntpr.2026.1884549
Original Research
Published
Immunoinformatics-guided design and in silico evaluation of BAFF- and APRIL-adjuvanted multi-epitope vaccine candidates against human metapneumovirus
Reham M. Alahmadi · Maaweya Awadalla · Halah Z. Al-Rawi · Ayman Mubarak · Wafa Ali Eltayb · Mohnad Abdalla · Han Yu · Bandar Alosaimi
Frontiers in Virology
doi 10.3389/fviro.2026.1949694
Original Research
Published
Immunoinformatics-based design of a multi-epitope mRNA vaccine candidate targeting the major human-infecting hepatitis E virus genotypes 1–4
Maham Mehrangaze Khonza · Zain Saeed · Zohra Jabeen · Wafaa Arab · Sehrish Kakakhel · Maham Yamin · Mazen M. Ghaith · Aneela Javed · Ali Zohaib · Rwaa H. Abdulal
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1922523
Review
Published
Chronic pain in the aging adult with sickle cell disease
Keesha Powell-Roach · Ugochi O. Ogu
Frontiers in Pain Research
doi 10.3389/fpain.2026.1907108
Original Research
Published
Phytochemical characterization and evaluation of antimicrobial activity of Eugenia sp.: antibacterial, antibiofilm and ampicillin-potentiating activities against resistant Staphylococcus aureus and Staphylococcus epidermidis
Patryne Luana da Silva Dantas · Leticia Bachmann · Alysson Camilla Blaese Gramkov · Thaynara Reichert · Nicole Prada Zibell · Maressa Danielli Dolzan · Matheus Santos Lourenço · Saulo Relison Tintino · Tatiani Karini Rensi Botelho · Diogo Alexandre Siebert · Luciano Vitali · Cícera Datiane de Morais Oliveira-Tintino · Isabel Daufenback Machado · Michele Debiasi Alberton
Frontiers in Natural Products
doi 10.3389/fntpr.2026.1920078
Mini Review
Published
Bridging soil health and human health: Mycobacterium vaccae as a keystone link
Camila Espinoza-Mendoza · Winfred Espejo · José E. Celis · Andy Banegas-Medina · Isis-Yelena Montes · Wanda Espejo-Contreras · Mauricio Schoebitz · Marco Sandoval
Frontiers in Soil Science
doi 10.3389/fsoil.2026.1957461
Original Research
Published
Effects of transcutaneous electrical nerve stimulation based on wrist-ankle acupuncture theory on the skeletal muscle repair and gut microbiota modulation in rats with gastrocnemius muscle injury
Haobin Cheng · Tingting Mai · Kai Chen · Mengcheng Cai · Fanfu Fang
Frontiers in Rehabilitation Sciences
doi 10.3389/fresc.2026.1742110
Original Research
Published
Electroacupuncture alleviates inflammatory pain by modulating the CXCL1/CXCR2 signaling axis in the spinal cord dorsal horn of rats
Xiazhen Xu · Ziyan Fang · Kaihua Song · Yang Shen · Chenxin Jiang · Mengchao Xu · Shouhai Hong
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1880288
Mini Review
Published
Curcumin as an adjunct in periodontal therapy: local effects, delivery systems, and clinical perspectives
Ana Carolina Aparecida Rivas · Mario Taba · Paola Gomes Souza
Frontiers in Dental Medicine
doi 10.3389/fdmed.2026.1861025
Systematic Review
Published
Brucea javanica oil emulsion as an adjunct to chemoradiotherapy in cervical cancer: a systematic review and meta-analysis of adverse effects reduction and immune enhancement
Buwei Han · Mingge Liang · Ding Qi · Yangfan Qu · Jinzhe Liu · Wenxia Ai · Yue Yang · Wenlan Li
Oncology Reviews
doi 10.3389/or.2026.1880668
Review
Published
Molecular hydrogen in cancer: reprogramming oncogenic signaling pathways and emerging pharmacological potential
Anirban Kumar Maity · Ajay Mallick · Debbie C. Crans · Srikanta Goswami · Soumyajit Roy
Frontiers in Chemical Biology
doi 10.3389/fchbi.2026.1915345
Case Report
Published
Urothelial carcinoma of the bladder with prostatic stromal invasion and early postoperative bone metastases: a case report
Cheng Wang · Mengyun Wang · Yue He
Frontiers in Urology
doi 10.3389/fruro.2026.1910163
Case Report
Published
Hereditary leiomyomatosis and renal cell carcinoma: a case report and literature review
Shuqi Zuo · Yafei Xue · Fei Wang · Honglin Guo · Min Cui · Xingbo Zhao · Xiaoyi Qi
Frontiers in Urology
doi 10.3389/fruro.2026.1907141
Systematic Review
Published
Occult squamous cell carcinoma presenting as oligometastatic lymphadenopathy. A systematic review with a case report
Łukasz Ważny · Jakub Ciesielka · Krzysztof Jakimów · Aleksandra Tobiasz · Paulina Kluszczyk · Grzegorz Owczarek · Mateusz Winder · Jerzy T. Chudek
Oncology Reviews
doi 10.3389/or.2026.1801426
Mini Review
Published
Leveraging ZBP1 signaling for cancer immunotherapy
Parth Desai · Chunxia Wen · Siddharth Balachandran
Frontiers in Cell Death
doi 10.3389/fceld.2026.1841599
Original Research
Published
Successful outcomes of pediatric dacryocystorhinostomy with adjunctive 5-fluorouracil
Alina K. Sinha · Ethan L. Kahana · Tomas E. Meijome · Adam Jacobson · Jane Z. Spadaro · Stella Y. Chung · Alon Kahana
Frontiers in Ophthalmology
doi 10.3389/fopht.2026.1805226
Review
Published
The molecular pathways of polyphenols in combating multidrug-resistant microbial superbugs: a comprehensive mechanistic review
Michael T. Bayode · Shina Oguntuase · Joseph Chimezie · Ayomide Okiti · Esther Oyedeji · Isaac Ajayi · Jeremiah Adesanya
Frontiers in Natural Products
doi 10.3389/fntpr.2026.1879559
Review
Published
Beyond static biomarkers: systems biology and AI for decoding cancer dynamics
Subhajit Dutta · Anjana Goli
Frontiers in Systems Biology
doi 10.3389/fsysb.2026.1855016
Brief Research Report
Published
Evaluating an RNA-based test for proliferation assessment and recurrence prediction in early HR+/HER2− breast cancer
Marcus Vetter · Elena Diana Chiru · Anna Gasior · Joanna Gorniak · Sara Rollinson · Leanne Gough · Mathew Harrison · Martina Sonderegger-Stalder · Matthias Matter · Simone Muenst · Christian Kurzeder
Pathology and Oncology Research
doi 10.3389/pore.2025.1612113
Original Research
Published
Efficacy and tolerability of scalp cooling in preventing alopecia during (neo)adjuvant chemotherapy for breast cancer
Dóra Sántha · Ágnes Dobi · Máté Iványi · Domonkos Válóczi · Zoltán Varga · Judit Oláh · Aliz Nikolényi
Pathology and Oncology Research
doi 10.3389/pore.2026.1612403
Case Report
Published
Durable disease control after multimodal therapy and platinum-based chemotherapy rechallenge in advanced clear cell adenocarcinoma of the urethra with lymph node metastases: a case report
Akihiro Maeda · Shohei Tobu · Shuhei Kusano · Maki Kawasaki · Hiroaki Kakinoki · Mitsuru Noguchi
Frontiers in Urology
doi 10.3389/fruro.2026.1865730
Original Research
Published
Proof-of-principle 4-marker spatial profiling reveals distinct, location-independent immune clusters in biliary tract cancers
Federico Rossari · Michele Sala · Margherita Rimini · Silvia Camera · Mara Persano · Giovanni Tonon · Chiara Bonini · Maria Giulia Cangi · Lorenza Pecciarini · Claudio Doglioni · Maurilio Ponzoni · Chiara Balestrieri · Federica Pedica · Andrea Casadei-Gardini
Pathology and Oncology Research
doi 10.3389/pore.2026.1612389
Case Report
Published
Case Report: The molecular profile of granular cell astrocytoma predicts aggressive clinical behavior, independent of morphology
Melanie Jensen · Pranoy Das · Oliver Wroe-Wright · Oscar MacCormac · Francesco Marchi · Ali Elhag · Yasir A. Chowdhury · Ross Laxton · Rebecca Ellmers · Omar Al-Salihi · Keyoumars Ashkan · Ranjeev Bhangoo · Francesco Vergani · Istvan Bodi · Zita Reisz · Jose Pedro Lavrador
Pathology and Oncology Research
doi 10.3389/pore.2026.1612388
Original Research
Published
Surgical management of ulcerative colitis-associated colorectal cancer in a 20-year period, a single-centre study
János Tajti · László Libor · Szabolcs Ábrahám · Zsolt Simonka · Anikó Maráz · Attila Paszt · Tamás Molnár · Judit Oláh · György Lázár
Pathology and Oncology Research
doi 10.3389/pore.2026.1612362
Brief Research Report
Published
Liquid-based genomic profiling in high-risk localized prostate cancer
Fabiana Bettoni · Elisângela Monteiro Coser · Ernande Xavier dos Santos · Amanda Rafaela Alves Canteli · Romualdo Morandi Filho · Vandeclécio Lira · Livia Loureiro · Marcia Dellamano · Raul Torrieri · Maria José Ferreira Alves · Leonardo Cardili · David Queiroz Borges Muniz · Éder Nisi Ilário · Roger Chammas · William Carlos Nahas · Diogo Assed Bastos · Anamaria Aranha Camargo
Frontiers in Urology
doi 10.3389/fruro.2026.1789586
Original Research
Published
Folic acid modulates the Notch1/NF-κB pathway in a rat model of lipopolysaccharide-activated hippocampal microglia
Marwa Abd El-kader · Eman A. E. Farrag · Randa El-Gamal · Eman Mohamed El Nashar · Areej M. Alshehri · Rashid A. Aldahhan · Khulood M. Al-khater · Sara El-Desouky · M. W. El-Sherbeni · Neven A. Ebrahim
Frontiers in Neuroanatomy
doi 10.3389/fnana.2026.1748518