Original ResearchPublished 14 September 2026Exploratory scaffold hopping strategies led to identification of novel histamine H 3 and H 4 receptor ligandsFlávia B. Lopes · Denise Mönnich · Gustavo A. B. Fernandes · Steffen Pockes · João Paulo S. FernandesFrontiers in Drug Discoverydoi 10.3389/fddsv.2026.1944403