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  • Original Research

    Published

    Low-affinity anti-HER2-CAR T cells efficiently eradicate HER2 + and HER2 low cancer cells with reduced toxicity on healthy tissue

    Leonard Knoedler · Konstantin Herfeld · Julian N. Scherer · Kaiji Fan · Dhyani Shah · Sascha Goettert · Luisa Becker · Iria Lloshi · Suqi Li · Dennis C. Harrer · Matthias A. Fante · Tobias Wertheimer · Roland Schelker · Severin Guetter · Misbah Tariq · Omer Khalid · Alexander Scheiter · Wolfgang Herr · Christian Schmidl · Moritz Jesinghaus · Markus Tschurtschenthaler · Hendrik Poeck · Markus Perl

    Frontiers in Bioengineering and Biotechnology

    doi 10.3389/fbioe.2026.1895507