ReviewPublished 9 October 2026Pharmacological regulation of chondrocyte ferroptosis by plant-derived metabolites in osteoarthritis: from molecular mechanisms to targeted nanodeliveryTianci Guo · Qi Liu · Jida Wang · Keming Ren · Longyao Zhang · Jinzhong Sheng · Aifeng LiuFrontiers in Pharmacologydoi 10.3389/fphar.2026.1949976
ReviewPublished 5 October 2026Lipid droplet–mitochondria crosstalk in osteoarthritis: linking lipid routing to metabolic mismatchGang Meng · Ruijie Hou · Ping Dong · Qiannan Chen · Xueyuan Li · Kai Hu · Zixuan Du · Rong Wang · Zhaoxin ZhongFrontiers in Molecular Biosciencesdoi 10.3389/fmolb.2026.1973436
Original ResearchPublished 30 September 2026Synovial fluid-derived extracellular vesicles modulate joint cell function in osteoarthritisAlvaro Compañ · Vittoria Carrabs · María Luisa Ferrándiz · Antonio Silvestre · Ignacio Muñoz · María Carmen Carceller · María Isabel GuillénFrontiers in Agingdoi 10.3389/fragi.2026.1894052
Original ResearchPublished 30 September 2026Integrated bulk and single-cell transcriptomic analyses with experimental validation identify PLOD1 as a diagnostic biomarker and TGF-β1-responsive profibrotic mediator in dupuytren’s diseaseXianjie Lin · Mingming Wang · Yutian Lin · Yinshen Zhu · Zhijiang Ye · Haoran ChenFrontiers in Molecular Biosciencesdoi 10.3389/fmolb.2026.1924451
ReviewPublished 30 September 2026Emerging NPR-B agonists for cartilage and bone: from CNP biology to translational compound designYasuhiko Ago · Amali Karunathilaka · Jacky M. Guerrero-Vargas · Shunji TomatsuFrontiers in Chemistrydoi 10.3389/fchem.2026.1949456
Original ResearchPublished 4 September 2026Synthesis, characterisation, and in vitro assessment of hyaluronic acid-coated solid lipid nanoparticles entrapping dexamethasone palmitate designed for intra-articular administrationJinxin Zhang · Rumi Khandelia · Bridget Hogg · Ahmad Z. Bahlool · Tom Hodgkinson · Sally-Ann Cryan · John O’Byrne · David J. BraydenFrontiers in Drug Deliverydoi 10.3389/fddev.2026.1809275
ReviewPublished 4 September 2026Neuropeptide Y signaling in osteoarthritis pain: neuroimmune mechanisms, joint remodeling, and translational opportunitiesHeng Qiu · Li Wang · Danni Luo · Yong HuangFrontiers in Pain Researchdoi 10.3389/fpain.2026.1884062
Original ResearchPublished 12 January 2026A blend of tamarind (Tamarindus indica) and turmeric (Curcuma longa) has more pronounced effects on cartilage explant homeostasis than turmeric aloneMichelina Crosbie · Rachel Lamon · Kailey Vanderboom · Jamie Souccar-Young · Wendy PearsonFrontiers in Natural Productsdoi 10.3389/fntpr.2025.1764266
PerspectivePublished 17 December 2025Hemoglobin as an oxygen gasoreceptorSavani AnbalaganActa Biochimica Polonicadoi 10.3389/abp.2025.15546
Medical EngineeringPublished 5 December 2023Synergetic support of cartilage homeostasis via coupled thermal-pressure stimuli: a transcriptomic study in human cartilage explantsYanheng Guo · Theofanis Stampoultzis · Dominique P. PiolettiFrontiers in Medical Engineeringdoi 10.3389/fmede.2023.1291191