Opinion
Published
On the physics of chromatin molecular complex: from phase-separation to membrane adsorption
Andrea Fontana · Andrea M. Chiariello
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1951961
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 69 articles
Review
Published
Functional single-cell omics in gynecological cancers immunotherapy: from heterogeneity dissection to clinical translation
Dong-mei Li · Kai-ge Pei · Bo-wen Yang · Ming-rong Qie · Jin-feng Xu · Lan Zhong · Liang Song
Frontiers in Immunology
doi 10.3389/fimmu.2026.1981010
Review
Published
Lactate dynamics at the Pseudomonas aeruginosa –host interface: bacterial metabolism, host defense, and emerging links to histone lactylation
Yi Jian · Zhijie Wu · Yuqiang Liang · Jin Cao · Mei Li · Fashuang Yang · Ke Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1979311
Review
Published
Microbial-derived metabolites in cancer: evidence boundaries, immune mechanisms and translational pathways
Xuefeng Shi · Shunjun Wang · Wenhao Ouyang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1947330
Review
Published
Role of histone post-translational modifications in preeclampsia: from pathogenesis to diagnostic and therapeutic strategies
Yuanxuan Ma · Renwei Zhang · Mengting Yang · Jingli Wang · Bo Hou · Shiguo Liu
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1973542
Review
Published
Decoding Zmiz1 : a key transcription coactivator in development and disease
Rajan K C · Anoushka Shenoy · Most Ayesha Siddika · Nehal R. Patel · Stryder M. Meadows · Maria J. Galazo
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1933470
Original Research
Published
Direct RNA sequencing-based multi-omics profiling reveals transcriptional and post-transcriptional remodeling in mice with diet-induced atherosclerosis
Xin Liu · Xueyu Han · Wenjun Qiu · Fengming Guo · Yan Guo · Yipeng Gao · Yuxin Liu · Ruichen Xu · Ke Hu · Bo Shen
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1953461
Original Research
Published
Gypenoside LI modulates autophagy-associated apoptosis in clear cell renal cell carcinoma by PPARG/PTEN/PI3K/AKT/mTOR/ULK1 signaling network
Ruyi Liu · Hao Yu · Hui Liu · Yujie Wei · Anxin Wang · Qi Huang · Hui Xu · Xiuming Li
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1956477
Case Report
Published
Case Report: Hyperinsulinemic hypoglycemia and arterial aneurysms in KAT6B-related disorder: case observation and literature perspective
Nicola Improda · Francesco Maria Rosanio · Giada Ballarin · Fabio Acquaviva · Giangiacomo di Nardo · Lorenza Lepore · Antonia Pascarella · Virginia Mirra · Maria Rosaria Licenziati
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1938759
Original Research
Published
Variable alterations in frequencies of CRISPR/Cas9-induced nucleotide deletion and insertion in transgenic maize callus tissues exposed to chromatin modifiers
Bettina Nagy · Aysha Jameel · Gábor V. Horváth · Katalin Török · Ferhan Ayaydin · Nikolett László · Divya Teja Dondapati · Sándor Mórocz · Zoltán Zombori · Györgyi Ferenc · Dénes Dudits
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1924094
Review
Published
The 19S proteasome as a therapeutic target in hematologic malignancies
Idaly M. Olivas · Mayra A. Gonzalez-Henry · Saeedeh Darvishi · Evelyn M. Esparza · Anna M. Eiring
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1918833
Original Research
Published
Alcohol and male infertility: is there a safe dose? Evidence of accessory gland dysfunction, oxidative stress, and sperm DNA damage
P. Jagadesh · T. B. Sridharan
Frontiers in Reproductive Health
doi 10.3389/frph.2026.1934203
Review
Published
Telomeric autophagy in human health, aging, and diseases
Xingyao Li · Xili Wu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1922188
Original Research
Published
Cellular, chromatin-accessibility, and spatial contextualization of bulk transcriptional patterns linked to positive peritoneal cytology in endometrial cancer
Jiangang Huang · Binglai Luo · Zhiqing Hu · Shuping Lin · Jinyong Wang · Meiyan Lin
Frontiers in Genetics
doi 10.3389/fgene.2026.1924936
Study Protocol
Published
Randomized non-inferiority within-patient trial of density gradient processing of sequential ejaculates versus centrifugation-free sperm separation device for ICSI in men with elevated sperm DNA fragmentation- study protocol
Vipin Chandra · Shashank Sanagoudar · Jayesh Shinde · Naval Shah · Isha Suwalka · Sandro C. Esteves
Frontiers in Urology
doi 10.3389/fruro.2026.1913330
Review
Published
High-order chromatin structures mediated by phase separation in cell senescence
Wenjing Sun · Boxian Li · Zhaoyong Xu · Jing Wang · Jing Cao · Yangzhong Wang · Jiale Wang · Wenbo Gu · Pengjun Xu · Liang Wang · Wenyan Xie
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1896884
Review
Published
Chromatin remodeling in bone organoids: from epigenetic regulation to disease modeling and therapeutic translation
Yuxin Zheng · Desheng Liu · Jun Hou · Hong Ding · Yingying He
Frontiers in Genetics
doi 10.3389/fgene.2026.1975296
Review
Published
From chromatin to proteostasis: multilevel gene regulation in Mendelian diseases
Himanshu Goel · Gunjan Garg
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1944086
Review
Published
Epigenetic, chromatin-associated, and epitranscriptomic regulation in chronic pain: mechanisms and translational prospects
Jianan You · Lei Li
Frontiers in Genetics
doi 10.3389/fgene.2026.1904744
Review
Published
Molecular strategies to enhance induced pluripotent stem cell reprogramming in buffalo (Bubalus bubalis)
Eduardo Baia de Souza · Kaiana Recchia · Naira Caroline Godoy Pieri · Nathalia Nogueira da Costa de Almeida · Moysés dos Santos Miranda · Fabiana Fernandes Bressan
Frontiers in Animal Science
doi 10.3389/fanim.2026.1886584
Original Research
Published
Covariate-adjusted AP-1 motif architecture and footprinting track olaparib-adaptive chromatin remodelling
Subhajit Dutta
Frontiers in Systems Biology
doi 10.3389/fsysb.2026.1859256
Original Research
Published
In silico transcriptomic analysis nominates TSPAN32 as a central node of SCFA-driven immunometabolic reprogramming in intestinal epithelial cells
Zahra Masood · Iqra Sarwar · Ayesha Sanam · Amber Zaidi · Muhammad Zulfiqah Sadikan
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1847552
Review
Published
Epigenetics in asthma: implications for treatable traits
Vasiliki Apollonatou · Argyro Vrouvaki · Marina Moustaka Christodoulou · Athanasios Fengas · Stelios Loukides · Evangelia Fouka
Frontiers in Allergy
doi 10.3389/falgy.2026.1929559
Mini Review
Published
At the nucleus of neuronal health: Drosophila insights into LaminB-dependent homeostasis in aging and cell death
Francesco Napoletano
Frontiers in Cell Death
doi 10.3389/fceld.2026.1954383
Mini Review
Published
Beyond RNA/DNA: exploring the emerging role of Poly(ADP-ribose): structure, function, and condensate formation
Lipika Baidya · Hung T. Nguyen
Frontiers in Biophysics
doi 10.3389/frbis.2026.1930609
Review
Published
KAT5: the epigenetic regulator of central nervous system diseases
Xiaoming Xin · Lingjuan Wu · Meichen Liu · Tian Liu · Zihan Yuan · Liang Zhang · Tongqing Duan · Lei Zhang · Xianmin Zhu
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1887674
Mini Review
Published
Before hormones: early sex-specific mechanisms shaping nervous system development, function, and postnatal disease susceptibility
Maria A. Tsiarli · Erica N. Larschan
Frontiers in Behavioral Neuroscience
doi 10.3389/fnbeh.2026.1888207
Hypothesis and Theory
Published
Relative Sertoli-cell FSH hyporesponsiveness as a potential contributor to sperm DNA fragmentation: a hypothesis-driven narrative review and proposal of the FERTILE framework
Hussein Kandil
Frontiers in Urology
doi 10.3389/fruro.2026.1915445
Mini Review
Published
Epigenetic regulation in medulloblastoma: from tumor heterogeneity to diagnostic, prognostic, and translational applications
Xinling Zhang · Lailing Du · Kewei Tian · Lening Chen · Xiaoping Li
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1909580
Original Research
Published
Evaluating high-fidelity CRISPR-Cas nucleases in nucleosomal contexts using a quantitative framework
Christopher R. Handelmann · Erin Skeens · George P. Lisi · Michael J. Buck
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1759382
Review
Published
XPA confers ability of endonucleases to act processively and to incise damaged nucleosomal DNA
Muriel W. Lambert · W. Clark Lambert
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10902
Original Research
Published
Functional phosphoproteomic analysis of SMG1 in nonsense-mediated mRNA decay and DNA damage repair in cancer
Apoorva K. A. Pai · Leona Dcunha · Athira Perunelly Gopalakrishnan · Samseera Ummar · Athira C. Rajeev · Rajesh Raju
Frontiers in Systems Biology
doi 10.3389/fsysb.2026.1788470
Review
Published
Seed germination: light-hormone-epigenome crosstalk at the dormancy-to-growth transition
Sunita Kushwah · Shibananda Sharma · Vikash Kumar
Frontiers in Plant Physiology
doi 10.3389/fphgy.2026.1870445
Review
Published
A cellular (bio) photon field in mitochondrial-chromatin cross-talk: a hypothesis
Roeland Van Wijk · Eduard P. A. Van Wijk
Frontiers in Photobiology
doi 10.3389/fphbi.2026.1872069
Methods
Published
Elucidation of chromatin loops among regulatory regions using Hi-TrAC
Yaqiang Cao · Qingsong Tang · Keji Zhao
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1858923
Editorial
Published
Editorial: Epigenetics and metabolism: a closed liaison in tumor cells
Serena Castelli · Nicolò Mangraviti · Rohan Kodgule
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1886632
Systematic Review
Published
Environmental epigenetic modifiers in neurodegenerative diseases: a systematic review of epigenomic mechanisms and therapeutic targets
Pranay Wal · Sunita Mishra · Debashish Pradhan · Ankita Wal · Debashis Purohit · Lalit Mohan Nainwal · Vivek Dhir · Amin Gasmi
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1833533
Brief Research Report
Published
Chromatin condensation dynamics during spermatogenesis and variation in detectability and spatial distribution of satellite DNAs outside constitutive heterochromatin in Tenebrio molitor
Patrik Majcen · Eva Šatović-Vukšić
Frontiers in Insect Science
doi 10.3389/finsc.2026.1858332
Review
Published
Mobile small RNAs as mediators of stress-induced epigenomic remodeling and systemic stress adaptation
Muhammad Daniyal Junaid · Muhammad Shahzad Iqbal · Muhammad Waqar Nasir · Muhammad Waseem Akhter
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1827933
Review
Published
The pioneering work of Howard Cedar and his team in unraveling the roles DNA methylation plays in regulating genome function
Eugin Destici · Eric Mendenhall · Alon Goren
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1754553
Mini Review
Published
Epi-liquidomics: redefining cancer diagnostics through epigenetic profiling
Shahper Nazeer Khan · Mohammad Harris Siddiqui · Aamir Ahmad · Luca Guarnera · Salamatu Tijjani Isah
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1813822
Original Research
Published
Evaluating the efficacy of SK1217 in attenuating pristane-induced lupus in mice
Swetha Kakkerla · Sridhar Kavela · Sathvika Chintalapani
Frontiers in Lupus
doi 10.3389/flupu.2026.1466123
Review
Published
Vernalization control in the Brassicaceae: a multidimensional translational landscape
Shuta Yano · Akhi Paul Chowdhury · Ayasha Akter · Ryo Fujimoto · Diana Mihaela Buzas · Kenji Osabe
Frontiers in Horticulture
doi 10.3389/fhort.2026.1791790
Original Research
Published
Clinicopathological and molecular features of solid pseudopapillary neoplasms: a retrospective series including a small subset of aggressive cases
Erdem Comut · Ahmet Celik · Alper Uguz · Orkan Ergun · Simge Baran · Asuman Argon · Deniz Nart · Funda Yilmaz · Nese Calli Demirkan
Pathology and Oncology Research
doi 10.3389/pore.2026.1612367
Original Research
Published
Global MyoG research 2004–2024: a bibliometric analysis of trends and translational implications
Luoming Hu · Weizhong Zhuang · Weimin Chen · Song Yang · Shuo Chen · Xin Wang · Qiang Gao · Jimei Chen
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10929
Review
Published
Skeletal muscle reprogramming in peripheral nerve injury: mechanisms, therapeutic roles, and complication management
Fuqiang Long · Xiaoru Pan · Anxin He · Xinlu Wang · Zairong Wei · Shaoying Gao
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10835
Review
Published
Non-canonical regulated cell death and epigenetic mechanisms in the nervous system
Adalberto Merighi · Claudia Castagna · Marco Sbriz · Laura Lossi
Frontiers in Cell Death
doi 10.3389/fceld.2026.1793102
Review
Published
The impact of epigenetics on tumor metabolism: Friend or foe in drug response?
Serena Castelli · Melania Franchini · Luigi Ferraro · Nicolò Mangraviti
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1755829