Original ResearchPublished 7 October 2026Natural polysaccharide-engineered POP@ZIF-67 nanoparticles coordinate antibacterial activity, macrophage polarization, and osteogenesis for chronic osteomyelitis therapyYunchang Zhao · Guangting Zhu · Mengxue Zhang · Yize Wu · Junwei Su · Jing Hu · Chao Jian · Ying YuanFrontiers in Bioengineering and Biotechnologydoi 10.3389/fbioe.2026.1935416