Original ResearchPublished 9 October 2026Multi-source data integration and ensemble machine learning analysis of the role of Corilagin in regulating endoplasmic reticulum stress and alleviating intestinal ischemia reperfusion injury in miceZhiyang Wang · Qin Han · Lijie Pang · Siyang Zheng · Xin Wang · Bin Tian · Kun Li · Bin Li · Feng Qiu · Yunpeng Diao · Ruqiang YuanFrontiers in Pharmacologydoi 10.3389/fphar.2026.1966534
ReviewPublished 8 October 2026Highlighting gaps in paediatric antifungal drugs: a qualitative synthesis of current data from the International Pediatric Association AMR Working GroupDhanya Dharmapalan · Madhumita Singh · Mortada El-Shabrawi · Thomas Murray · Ayebo Evawere Sadoh · Leonor Patricia Saltigeral Simental · Cyntia Ibanes-Gutiérrez · Elisavet Efstathiou · Hanan M. Fathy · Barbara Rath · Abdalla Modar Dali · Betty Nkansah Osei Mensah · Ekatherine Prokopiou · Andreas Sarantopoulos · Naveen Thacker · Joseph Haddad · Zoi Dorothea PanaFrontiers in Tropical Diseasesdoi 10.3389/fitd.2026.1970689
Original ResearchPublished 8 October 2026Characterizing and mitigating protocol-dependent gene expression bias in 3′ and 5′ single-cell RNA sequencingValeryia Shydlouskaya · S. M. Mansour Haeryfar · Tallulah S. AndrewsFrontiers in Bioinformaticsdoi 10.3389/fbinf.2026.1931243
ReviewPublished 8 October 2026Transformer models in cardiovascular medicine: current applications, translational challenges, and future directionsYang Yan · Gaoxiang Li · Taiwei Chen · Jinchuan Yan · Chen Wang · Ancai Yuan · Jiawen Zhang · Jun PuFrontiers in Artificial Intelligencedoi 10.3389/frai.2026.1962796
Original ResearchPublished 8 October 2026Prediction of conelet mortality rates in interior lodgepole pine using phenomic, nutritional, and environmental dataJulian Garcia-Abadillo · Julio Isidro y Sánchez · Diego Jarquin · Esteban Galeano · Barb R. ThomasFrontiers in Plant Sciencedoi 10.3389/fpls.2026.1845181
Original ResearchPublished 7 October 2026Acceptability of blinded continuous glucose monitoring for people with serious mental illness and type 2 diabetes: findings from an exploratory mixed-methods studyJennifer V.E. Brown · Ramzi A. Ajjan · Najma Siddiqi · Peter A. CoventryFrontiers in Clinical Diabetes and Healthcaredoi 10.3389/fcdhc.2026.1923186
Original ResearchPublished 7 October 2026Assessing digital factors influencing AI-led asset information management in hospital facilitiesMotheo Tjebane · Thabo KhafisoFrontiers in Digital Healthdoi 10.3389/fdgth.2026.1900969
PerspectivePublished 5 October 2026How AI-based techniques for brain tumour diagnosis can address data variabilityPaola Lecca · Michela LeccaFrontiers in Bioinformaticsdoi 10.3389/fbinf.2026.1916468
ReviewPublished 5 October 2026Toward interoperable bathymetric data in ocean observing systems: integrating hydrographic standards and FAIR data practicesFaisal AlsaaqFrontiers in Marine Sciencedoi 10.3389/fmars.2026.1949937
ReviewPublished 1 October 2026Human-centric digital twins in industry 5.0: technologies, applications, and future directionsSagheer Khan · Saifullah Tumrani · Nguyen Van Nam · Moataz Ahmed · Ashfaq Khan · Mushtaq KhanFrontiers in Robotics and AIdoi 10.3389/frobt.2026.1983733
Original ResearchPublished 28 September 2026Two decades of prescription opioid-related cardiovascular safety signals: a FAERS-based pharmacovigilance study using machine learningLi Ma · Johnna Berryhill · John Ihrie · Ru Chen · Beverly Lyn-Cook · Paul Rogers · Weigong Ge · Ningning Wu · Huixiao Hong · Weida Tong · Wen ZouFrontiers in Drug Safety and Regulationdoi 10.3389/fdsfr.2026.1898403
ReviewPublished 24 September 2026AI-driven multi-omics integration in breast cancer: clinical applications, immunotherapy prediction, and translational challengesZi-Yao Wang · Na Liu · Min-Bin ChenFrontiers in Molecular Biosciencesdoi 10.3389/fmolb.2026.1875788
ReviewPublished 16 September 2026Reproductive performance and predictive models for litter size in sows: a narrative reviewGladness Ntshehi · Khathutshelo Agree Nephawe · Peter Ayodeji Idowu · Takalani Judas MpofuFrontiers in Animal Sciencedoi 10.3389/fanim.2026.1896800
EditorialPublished 8 September 2026Editorial: Integrative single-cell and spatial multiomics: charting cellular architecture and disease microenvironmentsWenchong Chen · Jingjing Lu · Wancheng Guo · Boyu Li · Hang Zhang · Yilin Wang · Zhaokai Zhou · Ran XuFrontiers in Bioinformaticsdoi 10.3389/fbinf.2026.1983096
ReviewPublished 5 August 2026Decoding the rhizosphere microbiome against Sclerotium rolfsii: integrating multi-omics and AI-driven predictive modelsArpita Das · Praveen Boddana · Priyanka Paul · Padripta Banerjee · Siddhartha DasFrontiers in Microbiomesdoi 10.3389/frmbi.2026.1884781
Original ResearchPublished 5 August 2026Sex differences in early brain development in a multi-site ASD likelihood cohortGabriel Blanco-Gomez · Julie Scorah · Christian O’Reilly · Stefon van Noordt · Virginia Carter Leno · Sara Jane Webb · Mayada ElsabbaghFrontiers in Computational Neurosciencedoi 10.3389/fncom.2026.1868455
Original ResearchPublished 31 July 2026Soil texture classification and mapping in semi-arid regions using machine learning and EnMAP hyperspectral dataHassan Mosaid · Ahmed Barakat · Mohamed Bayad · Nora Ezouitine · Soufiane Hajaj · Hassan Ouakhir · Mohammed Hssaisoune · Khalid El Bahjaouy · Mohamed El garnaoui · Lhoussaine Bouchaou · El Houssaine BourasFrontiers in Soil Sciencedoi 10.3389/fsoil.2026.1864901
EditorialPublished 14 July 2026Editorial: Big data in systems biologyHolger HusiFrontiers in Systems Biologydoi 10.3389/fsysb.2026.1905528
EditorialPublished 11 May 2026Editorial: Multimodal brain data integration and computational modelingJony Sheynin · Maryam Naseri · Alejandro Luis CallaraFrontiers in Neuroinformaticsdoi 10.3389/fninf.2026.1838147
ICTPublished 3 December 2018Better Patient Outcomes Through Mining of Biomedical Big DataClemens Suter-CrazzolaraFrontiers in ICTdoi 10.3389/fict.2018.00030
Digital HumanitiesPublished 31 May 2018Big Data: Challenge and Opportunity for Translational and Industrial Research in HealthcareRiccardo L. Rossi · Renata M. GrifantiniFrontiers in Digital Humanitiesdoi 10.3389/fdigh.2018.00013
Digital HumanitiesPublished 1 May 2018Big Data as a Driver for Clinical Decision Support Systems: A Learning Health Systems PerspectiveArianna Dagliati · Valentina Tibollo · Lucia Sacchi · Alberto Malovini · Ivan Limongelli · Matteo Gabetta · Carlo Napolitano · Andrea Mazzanti · Pasquale De Cata · Luca Chiovato · Silvia Priori · Riccardo BellazziFrontiers in Digital Humanitiesdoi 10.3389/fdigh.2018.00008