ReviewPublished 12 October 2026Halogenated and metallic scaffolds as novel efflux pump inhibitors: mechanistic insight in overcoming antimicrobial and cross-domain resistanceManaf AlMatar · Raja Lakhal · Kamaleldin H. Kamaleldin · Arig Ibrahim-HashimFrontiers in Microbiologydoi 10.3389/fmicb.2026.1923157
CorrectionPublished 12 October 2026Correction: Mechanism-aware and safety-validated AI for drug repurposing: a critical review and translational pharmacology frameworkMoumita Hazra · Harishchander AnandaramFrontiers in Pharmacologydoi 10.3389/fphar.2026.2009326
Systematic ReviewPublished 8 October 2026Antimalarial and antiplasmodial compounds (2024–2026): a systematic review of synthetic, semi-synthetic, and natural agentsBertin Mikolo · Gelase Fredy Nsonde Ntandou · Hermeline Tabuna Nee NtalaniFrontiers in Tropical Diseasesdoi 10.3389/fitd.2026.1944733
Original ResearchPublished 8 October 2026Identification of microglia-associated hub genes and a CX3CR1/P2RY12 two-gene diagnostic model for cross-subtype epilepsy-associated cortical malformations: integrated transcriptomic analysis with external validationHongliang Zeng · Bin LiFrontiers in Neurosciencedoi 10.3389/fnins.2026.1954412
Original ResearchPublished 26 August 2026Repurposing MK0873 as a non-covalent hTERT-Targeting compound: a proof of concept studyMaham Ansari · Abdul Wali · Mohhamed Rasul · Kristina Gemzell Danielsson · Twana Alkasalias · Muhammad MushtaqFrontiers in Agingdoi 10.3389/fragi.2026.1783019
ReviewPublished 20 August 2026A survey of LLMs in drug discovery and precision medicineHasi Hays · William J. RichardsonFrontiers in Drug Discoverydoi 10.3389/fddsv.2026.1854899
Original ResearchPublished 29 May 2026High-throughput repurposing screen identifies a DHODH inhibitor as a potent antiviral candidate against chikungunya virusEliana Castro · Diego Ezequiel AlvarezFrontiers in Drug Discoverydoi 10.3389/fddsv.2026.1846068
Mini ReviewPublished 22 April 2026Training the next-generation of biomedical scientists through artificial intelligence-driven education and research in pharmacology and pharmaceutical sciencesSantosh Kumar · Ritu Karwasra · Weinan Zhou · Jayaraman Seetharaman · Bhupesh SinglaExperimental Biology and Medicinedoi 10.3389/ebm.2026.10988
ReviewPublished 31 March 2026Revisiting old drugs and drug combinations for polycythemia vera and related neoplasmsGökhan Mergen · Hans C. HasselbalchFrontiers in Hematologydoi 10.3389/frhem.2026.1749376
ReviewPublished 9 February 2026The impact of epigenetics on tumor metabolism: Friend or foe in drug response?Serena Castelli · Melania Franchini · Luigi Ferraro · Nicolò MangravitiFrontiers in Epigenetics and Epigenomicsdoi 10.3389/freae.2026.1755829
Original ResearchPublished 16 January 2026Enhancing structure-based virtual screening of MDM2–p53 inhibitors: a benchmark of machine learning vs. traditional docking scoring functionsMarcia Yineth Castillo Tarazona · Gian Pietro MiscioneFrontiers in Drug Discoverydoi 10.3389/fddsv.2025.1731262
Digital HumanitiesPublished 31 May 2018Big Data: Challenge and Opportunity for Translational and Industrial Research in HealthcareRiccardo L. Rossi · Renata M. GrifantiniFrontiers in Digital Humanitiesdoi 10.3389/fdigh.2018.00013
