Review
Published
Immunometabolic crosstalk between dysfunctional adipose tissue and the brain: implications for postoperative cognitive dysfunction in obesity
Ya-Jiao Hu · Juan Ni · Jin-Xi Zhang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1965479
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 94 articles
Mini Review
Published
A proposed retinal venular immune gate: a mini review of perivascular macrophages and basement-membrane organization
Zhiqing Huang · Zijian Huang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1970491
Hypothesis and Theory
Published
A SynNotch-PiggyBac gene circuit for inflammation-responsive IL-10 delivery in Alzheimer’s disease: a hypothesis and design framework
Suhani Gupta · Ronav Gupta
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1866161
Mini Review
Published
Molecular mechanisms underpinning cognitive reserve and resilience
Amber Chen · Sreenithi Bhuvaneshwaran · Yash Akkara · Thomas Burke · Robert Perneczky · Magdalena Sastre
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1957901
Original Research
Published
TSC1-mTORC1 signaling in Alzheimer’s disease: an integrated bioinformatic analysis linking gene expression to neuropathology
Zheng Liu · Yuchen Yu · Yu Wang · Shuohan Ning · Tongshuai Huang · Jingqi Li · Sihan Fan · Chaolong Lu
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1920487
Hypothesis and Theory
Published
Immunometabolic synaptopathy: linking metabolic syndrome to epileptogenesis through trained immunity and parvalbumin interneuron vulnerability
Baihui Zhang · Wenjin Wang · Tao Li · Hua Huang
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1979155
Case Report
Published
Glioblastoma, IDH-wildtype, with spontaneous transdural and calvarial invasion: a case report and literature review
Jianhang Lin · Jiayi Lin · Jiana Zhang · Haiqing Xie · Dawei Liu · Shaolei Guo
Frontiers in Medicine
doi 10.3389/fmed.2026.1908149
Original Research
Published
Cannabidiol preserves astrocyte viability and attenuates injury-induced glial stress responses across zebra finch song control nuclei
Dylan A. Marshall · Karen A. Litwa · Ken Soderstrom
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1972787
Original Research
Published
Influenza A (H1N1)pdm infection exacerbates behavioral, cognitive, and synaptic impairments in 5xFAD mice
Anastasiya Rakovskaya · Alexey Lozhkov · Valeria Tverdokhlebova · Yana Zabrodskaya · Egor Vinokurov · Valeria Kirenskaya · Alexander Erofeev · Angelika Garshinina · Valeria Zryacheva · Anna Shtro · Ekaterina Pchitskaya · Olga Vlasova · Ekaterina Elpaeva · Pavel Dav · Ilya Bezprozvanny · Andrey Vasin
Frontiers in Behavioral Neuroscience
doi 10.3389/fnbeh.2026.1955816
Original Research
Published
Identification of microglia-associated hub genes and a CX3CR1/P2RY12 two-gene diagnostic model for cross-subtype epilepsy-associated cortical malformations: integrated transcriptomic analysis with external validation
Hongliang Zeng · Bin Li
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1954412
Original Research
Published
Caveolin-1 defines astrocyte mechanobiology in the glial lamina of the optic nerve head
Anja K. Hoffmann · Anna Dlugosch · Michelle C. Geigenfeind · Amelie Seemann · Michael H. Elliott · Rudolf Fuchshofer · Andrea E. Dillinger
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1909639
Review
Published
Balloon cells in type II focal cortical dysplasia: developmental origins, molecular signatures, and epileptogenic mechanisms
Yan Gao · Xinna Ji · Shuo Feng · Yanyan Gao · Lingxue Li · Bing Wang · Xue Zhang · Qian Chen
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1963535
Original Research
Published
Multi-cohort meta-analysis, single-cell and Mendelian randomization analyses with experimental validation identify RHBDF2 as a shared mediator of ulcerative colitis and blood–brain barrier disruption
Jiongjiong Cheng · Aman Xu
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2026.1970578
Original Research
Published
Regional tau burden tracks with lower microglial HLA class II transcription in the human brain
Fan Li · Suqin Jin · Ping Wang · Hui Yang · Xianghua Zhuang · Feifei Feng · Peng Cheng
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1979981
Original Research
Published
Integrated transcriptomic and proteomic profiling reveals C3-associated hippocampal neuroimmune remodeling in sodium bicarbonate-treated sepsis-associated encephalopathy
Housheng Deng · Hua Ling · Lie Liu · Qiuli He · Hao Wang · Zhiming Zhang
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1954272
Original Research
Published
Nicotine and tobacco smoke reshape neuronal signaling networks from a single-nucleus transcriptomic perspective
Jian Jiang · Anfu Hu · Yixiao Jin · Xia Li · Guo-Jun Zhou · Yi Shen · Chengyun Xu · Xing Ji · Ximei Wu · Hong-Juan Wang
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1953804
Original Research
Published
Transspinal temporal interference stimulation enhances neuroplasticity-associated responses and facilitates motor recovery after spinal cord injury in mice
Peng Zheng · Yan Chen · Yujiao Yue · Xianbin Wang · Shuang Wu
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1950023
Systematic Review
Published
Circulating and cerebrospinal fluid soluble TREM2 levels and risk of perioperative neurocognitive disorders in surgical patients: a systematic review and meta-analysis
Haotian Wu · Yujie Wang · Zhifeng Gao · Huan Zhang
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1899745
Mini Review
Published
Astrocytes at the interface of peri-ictal breathing dysfunction and SUDEP
Isato Fukushi · Isamu Ozaki · Mieczyslaw Pokorski · Yasumasa Okada
Frontiers in Network Physiology
doi 10.3389/fnetp.2026.1955271
Original Research
Published
Electroacupuncture inhibits pyroptosis to improve motor function in an MPTP-induced mouse model of Parkinson’s disease
Yu-Chen Ying · Yi-Yue Dong · Guang-Yan Chen · Xi Wang · Qian Fan · Xi-Chen Wu · Yue-Lai Chen
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1968826
Original Research
Published
Coordinated cellular architecture reveals weakened cortical structure–behavior coupling in normal aging
Xiaoyi Zhan · Pengcheng Tan · Tirzah Tan · Chia-Chien Chen
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1932616
Original Research
Published
Transient synaptic refinement and glial adaptations after whisker denervation in adult mice
Sean Collier · Laxmi Iyer · Kimberly R. Byrnes · Emily Petrus
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1941129
Review
Published
Connectomes: a re-emerging hub dataset for neuroscience
Sebastian Kyllmann · Ian W. Keesey
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1911198
Original Research
Published
Divergent cellular responses to sciatic nerve crush versus transection: bilateral MYCN induction and distinct DRG neuronal responses
Shilian Zhou · Ziyan Huang · Zhongyuan Lin · Jingwei Chen · Xinyu Zhang · Diya Wang · Haihua Shu · Fang Ye
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1922426
Review
Published
Multipath interaction network of annexin A2: multifaceted regulation and translational perspectives in neurological diseases
Yong Guan · Ping Gu · Dachuang Guo · Liqiang Huang · Dongye Lian · Caicai Zhang · Jigao Feng · Hao Peng
Frontiers in Genetics
doi 10.3389/fgene.2026.1916220
Review
Published
HSV-1 infections of the prefrontal cortex: regional vulnerability, cellular mechanisms, and neurocognitive consequences
Hannah Chau · Julia Schurr · Jonna M. Leyrer-Jackson · Erin S. Honsa
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1887935
Review
Published
Epigenetic, chromatin-associated, and epitranscriptomic regulation in chronic pain: mechanisms and translational prospects
Jianan You · Lei Li
Frontiers in Genetics
doi 10.3389/fgene.2026.1904744
Review
Published
Hyperbaric oxygen therapy in sepsis-associated encephalopathy: pathophysiological rationale, preclinical evidence, and translational challenges
Yikun Xie · Yihao Li · Yujing Li · Shuai Chen · Guanqi Song · Hongyu Wang
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1941147
Review
Published
Purinergic signaling in the gut neuro-glial-immune axis: mechanisms of homeostasis, inflammation, and gastrointestinal dysfunction
Eduardo E. Valdez-Morales · Andrómeda Liñán-Rico · Raquel Guerrero-Alba
Frontiers in Gastroenterology
doi 10.3389/fgstr.2026.1954794
Original Research
Published
Protective effects of an aqueous extract from Pinctada fucata martensii mucus on ultraviolet A-induced skin photoaging: in vitro and in vivo evidence
Anqi Cao · Xiaohui Wang · Siwei Quan · Yingfa Qin · Wenjiang Cai · Junmin Quan
Frontiers in Natural Products
doi 10.3389/fntpr.2026.1961314
Review
Published
Microglial handling of myelin debris and remyelination after ischaemic stroke: recognition, intracellular processing, lipid fate, and oligodendroglial repair
Mingrui Song · Nan Bu · Long Wei · Jing Chen
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1945478
Review
Published
Stress-induced tunneling nanotube communication in CNS glial cells: implications for inflammatory demyelination and repair failure
Yanjun Liu · Mingming Li · Wei Liu · Jia Guo · Jian Yin
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1949981
Original Research
Published
ALDH1/2 deficiency modulates dieldrin-induced dopaminergic neurodegeneration and reactive glial morphometry in male mice
Omar A. Yanouri · Adam J. Schuller · Savannah M. Rocha · Aidan M. Briggs · Paul A. Martinez · Elizabeth Fernandez · Randy Strong · Xueshu Li · Hans-Joachim Lehmler · Jonathan A. Doorn · Ronald B. Tjalkens
Frontiers in Toxicology
doi 10.3389/ftox.2026.1888799
Review
Published
Guanfacine and HCN channels: bridging neuroinflammation and prefrontal cortex function in autism spectrum disorder
Kazuhiko Yamamuro · Takahira Yamauchi · Manabu Makinodan
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1915506
Original Research
Published
Diversity of glutamate receptors in glial cells of the mouse optic nerve
Nine F. Kompier · Marcus Semtner · Sophie Walter · Christian Steinhäuser · Christiane Nolte · Helmut Kettenmann
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1911068
Review
Published
Periodontitis and Alzheimer's disease, common pathways in down syndrome
Fabio Arriola-Pacheco · Alicia Leonor Pinzón-Té · Rodrigo Serrano-Piña · Bertha Arelly Carrillo-Ávila · Jaime Díaz-Zúñiga · Samanta Melgar-Rodríguez · Víctor Manuel Martínez-Aguilar
Frontiers in Dental Medicine
doi 10.3389/fdmed.2026.1930049
Review
Published
The effects of abused drugs on ferroptosis pathways: potential therapeutic targets for substance use disorders
Tamara Bouchard · Brooke Russell · Liam Liyang Guo · Tina Nguyen · Yan Cheng · Yan Y. Sanders · Ming-Lei Guo
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1899553
Review
Published
Neuroinflammation in postoperative cognitive dysfunction: the multi-target potential of esketamine in modulating microglial responses and synaptic integrity
Hao-Tian Li · Guang-Yong Lin · Wen-Tao Xing · Yu Liu · Chuan-Xiang Zhang
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1868647
Original Research
Published
Primary cell and tissue cultures of human choroid plexus epithelial cells
Ronja Bihlmaier · Melanie Scharr · Peter H. Neckel · Bernhard Hirt · Andreas F. Mack
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1827493
Editorial
Published
Editorial: Cellular and animal models of neurodegenerative and neuroinflammatory conditions
Juan Antonio García-León · Beatriz García-Díaz · David Baglietto-Vargas · Carlos J. Rodriguez-Ortiz
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1961369
Hypothesis and Theory
Published
Cervico-suboccipital sensorimotor convergence as an upstream autonomic pathway in bilateral rhythmic stimulation
Ioulia Milovanov
Frontiers in Integrative Neuroscience
doi 10.3389/fnint.2026.1862966
Original Research
Published
Rotenone-induced oxidative stress triggers peroxisomal alterations in BV-2 microglial cells
Alessio Valenza · Maurizio Muzzi · Francesca Rendina · Irene Montali · Daniele Pensabene · Anna Fracassi · Marco Segatto · Sandra Moreno
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1941513
Review
Published
From metabolism to neurodegeneration: how microglial functional reprogramming drives neurodegenerative diseases
Qiaoqiao Cui · Ke Zheng · Qiyun Liu · Lizhen Wang · Yixin Liu · Ruifang Bai · Wei Zhang · Junhong Guo · Xueli Chang · Juan Wang
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1921079
Original Research
Published
Collagen-induced restructuring of astrocytes and vessels in organotypic mouse brain slices
Eva Steiner · Valentin Wolfgang · Christian Humpel
Frontiers in Aging
doi 10.3389/fragi.2026.1910447
Review
Published
Microglia-mediated neuroinflammation in Alzheimer’s disease: mechanisms and emerging therapeutic targets
Lianjing Xu · Ying Zhang · Li Jiang · Jin Feng Xing · Jing Hu · Tianye Lan · Guang Ta
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1902577
Methods
Published
Open and closed loop differential target multiplexed spinal cord stimulation in patients with persistent spinal pain syndrome type II: protocol for a one year European multicenter cohort study (ENDLESS)
Lisa Goudman · Kliment Gatzinsky · Vivek Mehta · Kavita Poply · Ashish Gulve · Iris Smet · Paul Murphy · Dirk Rasche · Georgios Matis · Jan Willem Kallewaard · José Manuel Trinidad · Pasquale De Negri · Philippe Rigoard · ENDLESS consortium · Maarten Moens
Frontiers in Pain Research
doi 10.3389/fpain.2026.1922595
Hypothesis and Theory
Published
A minimal three-arm oral regimen for healthspan: mechanistic alignment with transcriptomic signals from a large parental-lifespan GWAS
Ngo Cheung
Frontiers in Aging
doi 10.3389/fragi.2026.1856979
Original Research
Published
Boldine treatment prevents chronic cognitive impairment and exaggerated fear learning in rats exposed to repetitive low-level blast injury
Georgina Perez Garcia · Gissel M. Perez · Rita De Gasperi · Miguel A. Gama Sosa · Serena Yeung · Carolyn W. Zhu · Patrick R. Hof · Jiangping Pan · Shahrukh Khalique · Alexey Kozlenkov · Wei Zhao · Carlos A. Toro · Gregory A. Elder · Christopher P. Cardozo
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1894226