ReviewPublished 12 October 2026Functional single-cell omics in gynecological cancers immunotherapy: from heterogeneity dissection to clinical translationDong-mei Li · Kai-ge Pei · Bo-wen Yang · Ming-rong Qie · Jin-feng Xu · Lan Zhong · Liang SongFrontiers in Immunologydoi 10.3389/fimmu.2026.1981010
Original ResearchPublished 9 October 2026A novel CAF-related gene signature for prognostic and immunotherapy response prediction in PDAC based on single-cell RNA-seq and bulk RNA-seq dataXuezhi Du · Zesheng Li · Yuwei Wang · Lei Han · Jinjin Sun · Weipeng GongFrontiers in Pharmacologydoi 10.3389/fphar.2026.1873756
Original ResearchPublished 7 October 2026Integrating transcriptomic analysis and experimental validation unravels autophagy- and lactylation-related gene signatures in acute myocardial infarctionJun Peng · Li Chen · Lizhen Liu · Xiangdong Xu · Huiwen SongFrontiers in Cardiovascular Medicinedoi 10.3389/fcvm.2026.1814910
Original ResearchPublished 6 October 2026Integrating Mendelian randomization with single-cell and spatial transcriptomics to investigate gut microbiota-associated genetic signals and molecular characteristics in prostate cancerChenjie Qiu · Huilin Zhang · Zongmin Du · Yuan Gao · Liangliang DaiFrontiers in Cellular and Infection Microbiologydoi 10.3389/fcimb.2026.1899354
Original ResearchPublished 30 September 2026Integrated bulk and single-cell transcriptomic analyses with experimental validation identify PLOD1 as a diagnostic biomarker and TGF-β1-responsive profibrotic mediator in dupuytren’s diseaseXianjie Lin · Mingming Wang · Yutian Lin · Yinshen Zhu · Zhijiang Ye · Haoran ChenFrontiers in Molecular Biosciencesdoi 10.3389/fmolb.2026.1924451
ReviewPublished 15 September 2026Stress-induced tunneling nanotube communication in CNS glial cells: implications for inflammatory demyelination and repair failureYanjun Liu · Mingming Li · Wei Liu · Jia Guo · Jian YinFrontiers in Cellular Neurosciencedoi 10.3389/fncel.2026.1949981
Original ResearchPublished 4 September 2026Alternative splicing remodeling and splicing factor regulatory networks define immune-associated molecular heterogeneity in dilated cardiomyopathyJia Li · Yiyu He · Xianxian Zhao · Zhifu Guo · Jinchao Song · Xiaowei SongFrontiers in Bioinformaticsdoi 10.3389/fbinf.2026.1934275
Original ResearchPublished 6 July 2026Transcriptomics-based identification of shared biomarkers across type 2 diabetes, mild cognitive impairment, and uric acid metabolismYan Liu · Dongmei Kang · Yuan LeiExperimental Biology and Medicinedoi 10.3389/ebm.2026.11060
Original ResearchPublished 15 April 2026Molecular mechanisms underlying psoriasis and depression: an integrated analysis using mendelian randomization, transcriptomics, and single-cell sequencingBaojun De · Wenfeng Bao · Nagongbilige Hea · Jun FangFrontiers in Molecular Medicinedoi 10.3389/fmmed.2026.1770665
Original ResearchPublished 2 March 2026Identification of potential hub genes related to ferroptosis and hypoxia in dilated cardiomyopathy: a bioinformatic analysis with preliminary experimental validationXiqin Wang · Chrismis Novalinda Ginting · William LeslieExperimental Biology and Medicinedoi 10.3389/ebm.2026.10709