Articles

Showing 28 articles

• Original Research

  Published 12 October 2026

  Identification and validation of biomarkers related to oxidative stress in pediatric sepsis utilizing WGCNA and multiple machine learning algorithms

  Yumeng Liu · Gang Luo

  Frontiers in Bioinformatics

  doi 10.3389/fbinf.2026.1745381

• Hypothesis and Theory

  Published 12 October 2026

  Influencing the exposome, patient macroenvironment, tumor microenvironment through-line to improve clinical outcomes

  Samuel F. Yanuck · Neil E. Alexis

  Frontiers in Oncology

  doi 10.3389/fonc.2026.1929067

• Original Research

  Published 12 October 2026

  Multi-cohort screening of PANoptosis-related genes reveals PARP1 as a key target, and AZD5305 exerts anti-tumor effects in neuroblastoma

  Shujun Shi · Zhaoxia Zhang · Junyi Luo · Zhaoying Wang · Tao Mi · Liming Jin · Xiangpan Kong · Jinkui Wang · Junhong Liu · Li Wang · Dawei He

  Frontiers in Oncology

  doi 10.3389/fonc.2026.1903085

• Mini Review

  Published 12 October 2026

  Autophagy as a potential link between progesterone responsiveness and endometrial immune function in recurrent implantation failure

  Li Guo · Jinghong Xie · Mengyu Wang · Shuang Ma · Xinyan Zhang · Yu Guan

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1990439

• Review

  Published 12 October 2026

  Functional single-cell omics in gynecological cancers immunotherapy: from heterogeneity dissection to clinical translation

  Dong-mei Li · Kai-ge Pei · Bo-wen Yang · Ming-rong Qie · Jin-feng Xu · Lan Zhong · Liang Song

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1981010

• Review

  Published 12 October 2026

  Glutamine metabolic reprogramming in acute and chronic kidney diseases: mechanistic insights and therapeutic implications

  Ruotong Xu · Jin Zhao · Minna Liu · Yifan Qiao · Xiaoxuan Ning · Shiren Sun

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1939528

• Review

  Published 12 October 2026

  Macrophage functional plasticity in periodontitis: microenvironmental regulation, disease progression, and therapeutic targeting

  Ziqi Gu · Xinyu Li · Gulinur Awuti

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1973755

• Review

  Published 12 October 2026

  Nutritional regulation of the tumor immune microenvironment: metabolic mechanisms, immunotherapy response, and nursing implications

  Danwei Zhong · Congjue Li · Zunyao Xiao

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1938564

• Mini Review

  Published 12 October 2026

  Spatial heterogeneity in glioblastoma: linking single-cell and spatial multi-omics to vaccine immunotherapy

  Juan Yuan · Yong Liu

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1921816

• Brief Research Report

  Published 12 October 2026

  Distinct spatial immune architectures in tumor and tumor-adjacent tissues of early-stage non-small cell lung cancer

  Isabella Polic · Claudio Arrechedera · Jared K. Slone · Amanda Montoya · Emily Bontekoe · Peixin Jiang · Anika Patel · Tatiana V. Karpinets · Xiaogang Wu · Xingzhi Song · Qianyun Luo · Heladio Ibarguen · Auriole Tamegnon · Mei Jiang · Cara Haymaker · Annikka Weissferdt · Ara A. Vaporciyan · Lydia E. Kavraki · Tina Cascone · Ignacio Wistuba · Luisa Maren Solis Soto · John V. Heymach · Jianjun Zhang · Don L. Gibbons · Alexandre Reuben

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1981839

• Correction

  Published 12 October 2026

  Correction: Effect and mechanism of Emodin on mouse myeloid-derived suppressor cells

  Frontiers Production Office

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.2001607

• Mini Review

  Published 9 October 2026

  Biomarker-guided immunotherapy in osteosarcoma: from immune microenvironment profiling to patient stratification and combination strategies

  Qingqing Li

  Frontiers in Medicine

  doi 10.3389/fmed.2026.1987146

• Original Research

  Published 9 October 2026

  Adverse reactions of immune checkpoint inhibitors combined with acetaminophen/non-steroidal anti-inflammatory drugs (NSAIDs): a pharmacovigilance analysis of drug–drug interactions

  Xiayang Ren · Lihui Xue · Yanfeng Wang · Jian Xiao

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1833275

• Systematic Review

  Published 8 October 2026

  Mapping the intellectual landscape of lactylation research: a bibliometric analysis of global trends and emerging frontiers

  Jieyan Wang · Zhou Li · Xiya Li · Xiyu Liu · Zhaohua Zhong · Yantong Wan · Hui Liang

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1841236

• Review

  Published 7 October 2026

  Gut mycobiome dysbiosis in digestive system cancers: immune remodeling and translational implications

  LingBo Ma · Zhen Wang · Jie Mao

  Frontiers in Cellular and Infection Microbiology

  doi 10.3389/fcimb.2026.1902754

• Systematic Review

  Published 7 October 2026

  Global research trends in m 6 A demethylases and cancer: a bibliometric and visualization analysis

  Hao Lei · Hui Guo · Rong Lei · Jumei Sun · Yuanhang Yu · Lei Li · Chunping Liu · Guanghua Fu

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1943884

• Original Research

  Published 6 October 2026

  Integrating Mendelian randomization with single-cell and spatial transcriptomics to investigate gut microbiota-associated genetic signals and molecular characteristics in prostate cancer

  Chenjie Qiu · Huilin Zhang · Zongmin Du · Yuan Gao · Liangliang Dai

  Frontiers in Cellular and Infection Microbiology

  doi 10.3389/fcimb.2026.1899354

• Original Research

  Published 6 October 2026

  scTIME: single-cell-informed interpretable modeling of immunotherapy-associated immune states in non-small cell lung cancer

  Guozhi Chen · Chenqiu You · Hong Gao · Chengjie Xu

  Frontiers in Artificial Intelligence

  doi 10.3389/frai.2026.1918104

• Original Research

  Published 1 October 2026

  Exploring the immune enhancement effect of radiotherapy combined with NK cells on non-small cell lung cancer based on proteomics technology

  Cui Chang · Tang Youming · Lu Ying · Lei Ningning · Guo Chunhui · Wei Dekai · Liang Mei · Wu Qiyuan · Liu Gechen · Wu Fasheng · Chen Jibing

  Oncology Reviews

  doi 10.3389/or.2026.1853377

• Original Research

  Published 30 September 2026

  Integrated bulk and single-cell transcriptomic analyses with experimental validation identify PLOD1 as a diagnostic biomarker and TGF-β1-responsive profibrotic mediator in dupuytren’s disease

  Xianjie Lin · Mingming Wang · Yutian Lin · Yinshen Zhu · Zhijiang Ye · Haoran Chen

  Frontiers in Molecular Biosciences

  doi 10.3389/fmolb.2026.1924451

• Original Research

  Published 24 September 2026

  Integrative multi-omics characterization of KLRB1/CD161 in diffuse large B-cell lymphoma: associations with immune context, subtype biology, and therapeutic response

  Erwei Li · Yingying Tang · Yuanyuan Wanyan · Yu Liang

  Frontiers in Molecular Biosciences

  doi 10.3389/fmolb.2026.1903725

• Original Research

  Published 23 September 2026

  Integrative oxidative stress–disulfidptosis analysis identifies NPR3 and ZNF366 as cell-type-associated candidate markers in clear cell renal cell carcinoma

  Ping Wang · Zhixuan Cai · Gaofeng Wu · Guangfeng Zhu

  Frontiers in Molecular Biosciences

  doi 10.3389/fmolb.2026.1912537

• Review

  Published 23 September 2026

  Recent progress in stimuli-responsive hydrogel-based drug delivery for inflammatory bowel disease

  Yuxin Zou · Yanze Wang · Miao Zhang · Xiaoxue Wei · Wenjun Liao · Xiaorui Wang · Honghua Li

  Frontiers in Materials

  doi 10.3389/fmats.2026.1960078

• Review

  Published 11 September 2026

  Analysis of the heterogeneity of the immune microenvironment of bone metastases and new strategies of nanotechnology intervention

  Chenyang Wu · Xueli Qiu · Chao Wang · Jinyu Bai · Xiaozhong Zhou

  Oncology Reviews

  doi 10.3389/or.2026.1820639

• Original Research

  Published 10 September 2026

  Palmitoylation-related lncRNAs link molecular signaling, immune remodeling, and tumor progression in glioma: prognostic modeling and functional validation of LYRM4-AS1

  Juan Xu · Chen Zhang · Lingling Pu · Xiaoyang Zhu · Xiaoan Sheng · Juanjuan Dong · Miaomiao Song · Chao Wang

  Frontiers in Molecular Neuroscience

  doi 10.3389/fnmol.2026.1901839

• Mini Review

  Published 22 July 2026

  Inflammation, infection, and immune dysregulation in chronic kidney disease: translational and epidemiological perspectives

  Aminu Shittu

  Frontiers in Nephrology

  doi 10.3389/fneph.2026.1919658

• Original Research

  Published 28 May 2026

  Proof-of-principle 4-marker spatial profiling reveals distinct, location-independent immune clusters in biliary tract cancers

  Federico Rossari · Michele Sala · Margherita Rimini · Silvia Camera · Mara Persano · Giovanni Tonon · Chiara Bonini · Maria Giulia Cangi · Lorenza Pecciarini · Claudio Doglioni · Maurilio Ponzoni · Chiara Balestrieri · Federica Pedica · Andrea Casadei-Gardini

  Pathology and Oncology Research

  doi 10.3389/pore.2026.1612389

• Epigenetics and Epigenomics

  Published 4 September 2024

  Quantification of tumour-infiltrating immune cells through deconvolution of DNA methylation data in Ewing sarcomas

  Sara Patrizi · Silvia Vallese · Lucia Pedace · Claudia Nardini · Alessandra Stracuzzi · Sabina Barresi · Isabella Giovannoni · Luana Abballe · Celeste Antonacci · Ida Russo · Angela Di Giannatale · Rita Alaggio · Franco Locatelli · Giuseppe Maria Milano · Evelina Miele

  Frontiers in Epigenetics and Epigenomics

  doi 10.3389/freae.2024.1427399