Review
Published
Tumor antigens across cancer progression: from immune recognition and selection to precision cancer immunotherapy
Stanley P. Leong
Frontiers in Immunology
doi 10.3389/fimmu.2026.1939919
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Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 25 articles
Original Research
Published
Design of multi-epitope vaccine based on G2c genotype PEDV antigen and its immunogenicity and protective effect in piglets
Hao Luo · Zaixing Sun · Jingxin Wang · Lin Lan · Baoning Wang
Frontiers in Veterinary Science
doi 10.3389/fvets.2026.1942409
Original Research
Published
Design of a tetravalent dengue vaccine incorporating T-cell epitopes from NS3 and NS5 proteins and B-cell epitopes from the envelope protein using an immunoinformatics approach
Theerawat Dobutr · Pemikar Srifa · Nawamin Pinpathomrat
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1934834
Review
Published
Advances and applications of engineered protein therapeutics and their role in precision medicine
Wadha Aldossary · Nada Alqahtani · Layla Asiri · Noora Alkhurayef · Samar Alagl · Sana Alturki · Duha Saad · Mashael Al Yahya · Samah Al-Harthi
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1857362
Original Research
Published
Immunoinformatics-guided design and in silico evaluation of BAFF- and APRIL-adjuvanted multi-epitope vaccine candidates against human metapneumovirus
Reham M. Alahmadi · Maaweya Awadalla · Halah Z. Al-Rawi · Ayman Mubarak · Wafa Ali Eltayb · Mohnad Abdalla · Han Yu · Bandar Alosaimi
Frontiers in Virology
doi 10.3389/fviro.2026.1949694
Original Research
Published
Immunoinformatics-based design of a multi-epitope mRNA vaccine candidate targeting the major human-infecting hepatitis E virus genotypes 1–4
Maham Mehrangaze Khonza · Zain Saeed · Zohra Jabeen · Wafaa Arab · Sehrish Kakakhel · Maham Yamin · Mazen M. Ghaith · Aneela Javed · Ali Zohaib · Rwaa H. Abdulal
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1922523
Original Research
Published
The optimized endolysosomal degradation assay with standardized enzyme activity represents an orthogonal method for predicting protein immunogenicity and T cell epitopes
Elif Öztemiz · Christof Regl · Hans Brandstetter · Christian G. Huber · Kitty Verhoeckx · Gabriele Gadermaier
Frontiers in Allergy
doi 10.3389/falgy.2026.1936335
Review
Published
Animal reuse in safety assessment studies: a review of current practices, challenges and 3Rs opportunities
John S. Kendrick · David A. Shaw · Marie Jourdain · Claudia Senn · Helen Beyer · Fiona R. Sewell
Frontiers in Toxicology
doi 10.3389/ftox.2026.1854281
Review
Published
Advancements in CRISPR-based in vivo gene therapy for hemophilia
Xiaoyu Zhang · Kaidi Xu · Shihui Zou · Zhiyao Zhu · Shuzhi Teng · Ping Huang
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1924733
Review
Published
Nipah virus vaccine development: current platforms, preclinical evidence, and clinical translation
Shrabonti Chatterjee · Joydeep Mahata · Athika Firdous · Moh. Royhan Afnani · Rangga Adhi Prastika · Muhammad 'Ahdi Kurniawan · Volta Kellik Setiawan · Farah Arini Subekti · Fara Disa Durry · Sukma Sahadewa · Aswin Rafif Khairullah · Yudhi Nugraha · Tegar Achsendo Yuniarta · Timotius Ivan Hariyanto · Abhishek Singh · Vikash Jakhmola · Nitin Sharma · Abdugani Abdurasulov · Maksim Rebezov · Arif Nur Muhammad Ansori · Rollando Rollando · Arli Aditya Parikesit
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1906594
Original Research
Published
Innate immune activation profiles are associated with polarization of the T cell response to recombinant arenaviral vectors
Sarah Szaffich · Valentin Just · Natalija Cvetkovic · Naila Pepic · Michael Schwendinger · Kia Katchar · Klaus K. Orlinger · Henning Lauterbach · Josipa Raguz · Katell Bidet Huang
Frontiers in Systems Biology
doi 10.3389/fsysb.2026.1897043
Review
Published
Oral absorption of high molecular weight polyethylene glycols: mechanistic, safety and regulatory insights
Chiara G. M. Gennari · Sara Azari · Antonella Casiraghi · Umberto M. Musazzi
Frontiers in Drug Safety and Regulation
doi 10.3389/fdsfr.2026.1851318
Review
Published
Elastin-like polypeptides in radiopharmaceutical delivery: current evidence, design principles, and translational challenges
Haidong Tian · Kepei Yang · Hongyan Li · Jianxi Xiao
Frontiers in Biomaterials Science
doi 10.3389/fbiom.2026.1911811
Brief Research Report
Published
Outer membrane vesicle loaded thin films as a stable room temperature vaccine platform
Nolan M. Randall · Julia Squissato · Cagla Numanoglu · William Dubois · Hannah Lee · Stephanie M. Curley
Frontiers in Biomaterials Science
doi 10.3389/fbiom.2026.1913356
Original Research
Published
Breadth of neutralization induced by vYF next generation yellow fever vaccine
Yves Girerd-Chambaz · Elisabeth Marion · Joseline Ruiz · Nathalie Mantel
Frontiers in Virology
doi 10.3389/fviro.2026.1833390
Review
Published
Fish waste collagen: a sustainable bioresource for innovative functional foods and nutraceuticals
Anand Vaishnav · Jam Lal · Naresh Kumar Mehta · Soibam Khogen Singh · Mocherla Bhargavi Priyadarshini · Kumar Gaurav · Shivbhajan Chandravanshi · Aditya Singh · Nitesh Kumar Yadav · Bikash Kumar Pati · Nongthongbam Sureshchandra Singh
Frontiers in Aquaculture
doi 10.3389/faquc.2026.1755817
Mini Review
Published
The application of CRISPR gene-editing technology in influenza prevention and control
Xinyi Zhang · Hangyi Shi · Jianlan Yang · Lailing Du · Xinling Zhang · Xiaoping Li
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1844919
Review
Published
Analytical similarity as the primary determinant of monoclonal antibody development: toward evidence-efficient regulatory frameworks
Sarfaraz K. Niazi
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1801236
Systematic Review
Published
Nanoparticle-mediated mRNA delivery for cancer, autoimmunity, and genetic diseases: a rapid review
Okechukwu Paul-Chima Ugwu · Fabian C. Ogenyi · Mariam Basajja · Chinyere N. Ugwu · Mundu M. Mustafa · Michael Ben Okon
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1793322
Review
Published
The role of necroptosis as a possible therapeutic target in multiple myeloma: the emerging roles of necroptosis
Duygu Aydemir
Frontiers in Hematology
doi 10.3389/frhem.2026.1686097
Original Research
Published
A next-generation strategy for HIV-1 vaccination: computational design of a multi-epitope subunit vaccine targeting global circulating variants
Sajid Khan · Zarlish Attique · Muhammad Hamza · Lingyu Li · Muhammad Imran · Li Yu · Suping Zhang
Frontiers in Virology
doi 10.3389/fviro.2025.1705632
Bacteriology
Published
Safety and immunogenicity of a recombinant double-mutant heat-labile toxin derived from enterotoxigenic Escherichia coli in healthy Bangladeshi adults delivered by three different routes
Taufiqur Rahman Bhuiyan · Farhana Khanam · Salima Raiyan Basher · Pinki Dash · Mohiul Islam Chowdhury · Shahinur Haque · Nabila Binte Harun · Aklima Akter · Polash Chandra Karmakar · Al Hakim · Shaheena Amin · Mohammad Kamruzzaman · Nasrin Parvin · Tasnuva Ahmed · Jessica Butts · Marcela F. Pasetti · Rezwanul Wahid · Marcelo B. Sztein · Nicole Maier · Jessica A. White · Kay M. Tomashek · A. Louis Bourgeois · Shahida Baqar · Karen L. Kotloff · Firdausi Qadri · Wilbur H. Chen
Frontiers in Bacteriology
doi 10.3389/fbrio.2025.1567791
Drug Delivery
Published
Gene hydrogel platforms for targeted skin therapy: bridging hereditary disorders, chronic wounds, and immune related skin diseases
Liangtao Li
Frontiers in Drug Delivery
doi 10.3389/fddev.2025.1598145
Drug Delivery
Published
Corrigendum: Preliminary results on novel adjuvant combinations suggest enhancement immunogenicity of whole inactivated pandemic influenza vaccines
Allegra Peletta · Aurélie Marmy · Samo Guzelj · Alcidia Ramos Barros · Žiga Jakopin · Gerrit Borchard
Frontiers in Drug Delivery
doi 10.3389/fddev.2024.1519969
Analytical Science
Published
Reliable particle sizing in vaccine formulations using advanced dynamic light scattering
Coline Bretz · Andrea Jauslin · Dario Leumann · Marius Koch · Andrea Vaccaro
Frontiers in Analytical Science
doi 10.3389/frans.2024.1358893