Original ResearchPublished 12 October 2026Incremental prognostic value of the T-helper 1/T-helper 2 immune phenotype and 72-h change in sequential organ failure assessment for in-hospital mortality in sepsis with and without type 2 diabetes: a retrospective two-cohort studyDongxu Pan · Zongnan Lv · Jiayan Li · Bo Zhang · Feifei Xu · Wuxiang Huang · Wei Chen · Xuejun MoFrontiers in Medicinedoi 10.3389/fmed.2026.1911557
ReviewPublished 12 October 2026Plant-derived extracellular nanovesicles in musculoskeletal repair and functional rehabilitation: mitochondrial–immune–metabolic regulationNingning Zhu · Ningrui Wang · NaNa Zhou · Baodong Ye · Jingjing LiuFrontiers in Chemistrydoi 10.3389/fchem.2026.1968520
ReviewPublished 12 October 2026Obesity-driven inflammation and immune dysregulation in cancer development and progressionPritika Pandey · Jeb F. Struder · Erika T. Rezeli · Evan M. Paules · Stephen D. Hursting · Michael F. Coleman · Kristin A. AltweggFrontiers in Oncologydoi 10.3389/fonc.2026.1947958
PerspectivePublished 12 October 2026From macrofungal polysaccharides to precision microbial immunotherapy: reprogramming the tumor microenvironment through immunometabolic and gene-regulatory pathwaysKingsley Excel Dunga · Sylvester Chibueze Izah · Ebinyo Rebecca Aseibai · Matthew Chidozie Ogwu · Vivian Ibienebakabobo Promise · Nsikak Godwin Etim · Irene Nneka OhanusiFrontiers in Oncologydoi 10.3389/fonc.2026.1966586
ReviewPublished 12 October 2026Immunometabolic crosstalk between dysfunctional adipose tissue and the brain: implications for postoperative cognitive dysfunction in obesityYa-Jiao Hu · Juan Ni · Jin-Xi ZhangFrontiers in Immunologydoi 10.3389/fimmu.2026.1965479
ReviewPublished 12 October 2026Glutamine metabolic reprogramming in acute and chronic kidney diseases: mechanistic insights and therapeutic implicationsRuotong Xu · Jin Zhao · Minna Liu · Yifan Qiao · Xiaoxuan Ning · Shiren SunFrontiers in Immunologydoi 10.3389/fimmu.2026.1939528
ReviewPublished 12 October 2026Macrophage functional plasticity in periodontitis: microenvironmental regulation, disease progression, and therapeutic targetingZiqi Gu · Xinyu Li · Gulinur AwutiFrontiers in Immunologydoi 10.3389/fimmu.2026.1973755
ReviewPublished 12 October 2026Epigenetic and mitochondrial regulation in kidney disease: emerging mechanisms and therapeutic opportunitiesAtul Rawat · Narayan Prasad · Chandan Komalkumar · Harshit Singh · Saurabh Chaturvedi · Sultan Ahmed · Brijendra Kumar · Ravi Shankar KushwahaFrontiers in Immunologydoi 10.3389/fimmu.2026.1910925
Mini ReviewPublished 12 October 2026T-cell metabolic reprogramming in systemic lupus erythematosus: linking intracellular metabolism to effector differentiation and senescent-like/exhausted-like statesYi Zou · Zhichu Ren · Yuki Kudo · Michihito KonoFrontiers in Immunologydoi 10.3389/fimmu.2026.1961063
Mini ReviewPublished 12 October 2026Metabolic stress and macrophage efferocytosis in osteoarthritis: mechanisms and therapeutic implicationsHaoYang Wu · DeChao Yuan · RenJian He · ShiWei LiuFrontiers in Immunologydoi 10.3389/fimmu.2026.1999085
ReviewPublished 9 October 2026Metabolic reprogramming and metabolic homeostasis in podocyte injury: novel mechanistic insights and natural product therapiesZhongjie Qu · Wenqing Ba · Meijing Tang · Wenze Jiang · Mengting Zhu · Keda LuFrontiers in Cell and Developmental Biologydoi 10.3389/fcell.2026.1978760
ReviewPublished 8 October 2026Nutrition, thyroid function, and tuberculosis: exploring the endocrine–immune axisNooneh Khachatourian · Rubina Takhmazian · Vishwanath VenketaramanFrontiers in Tuberculosisdoi 10.3389/ftubr.2026.1945832
Original ResearchPublished 8 September 2026In silico transcriptomic analysis nominates TSPAN32 as a central node of SCFA-driven immunometabolic reprogramming in intestinal epithelial cellsZahra Masood · Iqra Sarwar · Ayesha Sanam · Amber Zaidi · Muhammad Zulfiqah SadikanFrontiers in Bioinformaticsdoi 10.3389/fbinf.2026.1847552
ReviewPublished 24 August 2026Mitochondrial control of blood-brain barrier homeostasis in neuroinflammatory psychiatric disordersLarli Misael Pérez-López · Alberto Camacho-Morales · Ivón Howland-Álvarez · Antonio Alí Pérez-MayaFrontiers in Molecular Neurosciencedoi 10.3389/fnmol.2026.1924581
ReviewPublished 20 August 2026From metabolism to neurodegeneration: how microglial functional reprogramming drives neurodegenerative diseasesQiaoqiao Cui · Ke Zheng · Qiyun Liu · Lizhen Wang · Yixin Liu · Ruifang Bai · Wei Zhang · Junhong Guo · Xueli Chang · Juan WangFrontiers in Molecular Neurosciencedoi 10.3389/fnmol.2026.1921079
Original ResearchPublished 10 April 2026Immunometabolic reprogramming of Mycobacterium tuberculosis -responsive memory CD4 + T cell subsets is linked to long-term protective immunityVaishnavi Kaipilyawar · Samantha Leong · Arianne Lovey · Lorenzzo L. Stringari · Reynaldo Dietze · Jerrold J. Ellner · Rodrigo Ribeiro-Rodrigues · Padmini SalgameFrontiers in Tuberculosisdoi 10.3389/ftubr.2026.1783887
ReviewPublished 12 December 2025Mycobacteria as evolutionary drivers of host innate immunity: insights from comparing experimental host modelsMariona Cortacans · Pere-Joan CardonaFrontiers in Tuberculosisdoi 10.3389/ftubr.2025.1735950
