Mini Review
Published
SIRT2 in metabolism, aging, and longevity
Menghui Li · Yihuan Dong · Wen Ren · Weixia Dong · Shaoping Ji
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1990670
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 45 articles
Original Research
Published
Comparative transcriptomic analysis reveals the protective mechanism of ferulic acid against lipopolysaccharide-induced ferroptosis in IPEC-J2 cells
Jiayu Chen · Hongchao Li · Yaxuan Niu · Tao Guo · Xiangyu Wang · Yue Zhang · Wenwen Wang · Yuanqing Xu · Yuan Wang · Mingxing Chu
Frontiers in Veterinary Science
doi 10.3389/fvets.2026.1950560
Review
Published
Immunometabolic crosstalk between dysfunctional adipose tissue and the brain: implications for postoperative cognitive dysfunction in obesity
Ya-Jiao Hu · Juan Ni · Jin-Xi Zhang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1965479
Review
Published
Lactate dynamics at the Pseudomonas aeruginosa –host interface: bacterial metabolism, host defense, and emerging links to histone lactylation
Yi Jian · Zhijie Wu · Yuqiang Liang · Jin Cao · Mei Li · Fashuang Yang · Ke Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1979311
Mini Review
Published
T-cell metabolic reprogramming in systemic lupus erythematosus: linking intracellular metabolism to effector differentiation and senescent-like/exhausted-like states
Yi Zou · Zhichu Ren · Yuki Kudo · Michihito Kono
Frontiers in Immunology
doi 10.3389/fimmu.2026.1961063
Original Research
Published
SCD1 inhibition promotes lipid peroxidation and enhances anti-PD-1 response in triple-negative breast cancer
Quentin Herrera Garfia · Aurélien Azam · Eric Bonneil · Laetitia Montero-Ruiz · Mohsen Momeni · Mohammad Farran · Robin Jehay · Nor Eddine Sounni
Frontiers in Immunology
doi 10.3389/fimmu.2026.1843935
Original Research
Published
Metformin and atorvastatin ameliorate MASH via the AMPK/NF-κB pathway
Bin Zhang · Na Li · Fang Liu · Guorui Wang · Quanwei Chen · Yiming Sun · Ni Yang · Hao Zhang · Jianjun Han
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1972846
Original Research
Published
Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and post-stroke depression in patients with acute ischemic stroke
Yu Yun · Jie Liu · Yaqiang Li
Frontiers in Psychiatry
doi 10.3389/fpsyt.2026.1882234
Systematic Review
Published
Effects and safety of acupuncture on inflammatory biomarkers in patients with coronary heart disease: a systematic review and meta-analysis
Linghao Meng · Di Sun · Houfang Ma · Shuhan Zhao · Songyan Bai · Wenzeng Zhu · Limei Zhang · Shuai Shi
Frontiers in Cardiovascular Medicine
doi 10.3389/fcvm.2026.1891405
Review
Published
Pharmacological regulation of chondrocyte ferroptosis by plant-derived metabolites in osteoarthritis: from molecular mechanisms to targeted nanodelivery
Tianci Guo · Qi Liu · Jida Wang · Keming Ren · Longyao Zhang · Jinzhong Sheng · Aifeng Liu
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1949976
Original Research
Published
Association between changes in obesity- and lipid-related indices and the risk of cardiovascular disease: a prospective cohort study in Northwest China
Jinlong You · Wu Ding · Xue Wang · Jing Tang · Xiuqian Li · Rui Wang · Yuanyuan Li · Yana Bai · Minzhen Wang · Shan Zheng
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1975120
Review
Published
Metabolic-inflammatory heterogeneity in PCOS assisted reproduction: a compartmental susceptibility model
Lin Yuying
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1963493
Systematic Review
Published
Berberine and metabolic dysfunction-associated steatotic liver disease: a global analysis of molecular mechanisms, translational challenges and research frontiers
Fei Yu · Sihan Yin · Jiayu Zhu · Kewei Sun
Frontiers in Nutrition
doi 10.3389/fnut.2026.1969017
Original Research
Published
Integrated gut microbiome and serum metabolomics identify candidate metabolic signatures of uric acid nephropathy
Min Cui · Sheng Li · Chenyu Wang · Jingxiu Dou · Yunyun Zhu · Qin Chen
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1941602
Original Research
Published
Direct RNA sequencing-based multi-omics profiling reveals transcriptional and post-transcriptional remodeling in mice with diet-induced atherosclerosis
Xin Liu · Xueyu Han · Wenjun Qiu · Fengming Guo · Yan Guo · Yipeng Gao · Yuxin Liu · Ruichen Xu · Ke Hu · Bo Shen
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1953461
Original Research
Published
Response of broiler chickens fed low-energy diets to increase levels of lysolecithin: linking growth performance with lipid metabolism gene expression, gut microbial modulation, intestinal morphology, and economic efficiency
Hanan S. Al-Khalaifah · Wafaa A. Eleraky · Sabry A. A. El-Sayed · Basant M. Shafik · Asmaa T. Y. Kishawy · Doaa Ibrahim · Shimaa A. E. Atwa · Sherief M. Abdel-Raheem · Marwa El-Shahat · Khalid Youssif · Anaam E. Omar
Frontiers in Veterinary Science
doi 10.3389/fvets.2026.1921649
Original Research
Published
Nicotine and tobacco smoke reshape neuronal signaling networks from a single-nucleus transcriptomic perspective
Jian Jiang · Anfu Hu · Yixiao Jin · Xia Li · Guo-Jun Zhou · Yi Shen · Chengyun Xu · Xing Ji · Ximei Wu · Hong-Juan Wang
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1953804
Original Research
Published
A comprehensive comparison of single- and composite-seaweed feeds on growth performance, lipid metabolism, and immune function of large yellow croaker (Larimichthys crocea)
Yueming Dang · Liyue Chai · Ruochen Xia · Sifeng Zhu · Guoyi Li · Rui Yang · Jianping Wang · Juanjuan Chen · Qiqin Liu
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1947273
Original Research
Published
Time-restricted feeding during the inactive phase vs. ad libitum feeding: diet-dependent effects on weight and metabolic markers in male Wistar rats
Ladan Hajhamidiasl · Murat Baş · Ozgur Yilmaz · Samed Ozer · Salim Yilmaz · Sedat Arslan
Frontiers in Nutrition
doi 10.3389/fnut.2026.1968504
Original Research
Published
Stage-specific transcriptional atlas of goose satellite cells uncovers sex-biased molecular dynamics associated with embryonic skeletal muscle development
Cui Wang · Kai Shi · Yi Liu · Yongping Yang · Guitao Jiang · Chuang Li · Shufang Chen · Huiying Wang · Daqian He
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1957937
Review
Published
M 6 A modification in lipid metabolism and related diseases
Zhiwen Hu · Didi Yuan · Xi Feng · Sai Hu
Frontiers in Genetics
doi 10.3389/fgene.2026.1890451
Original Research
Published
Mapping DEHP-induced metabolic dysregulation through multi-omics and systems biology: an adverse outcome pathway network approach
Elisavet Renieri · Achilleas Karakoltzidis · Nafsika Papaioannou · Dayna R. Schultz · Thanasis Papageorgiou · Catherine Gabriel · Ilias S. Frydas · Kévin Bernal · Xavier Coumoul · Etienne B. Blanc · Normand Podechard · Hélène Le Mentec · Charbel Touma · Sophie Langouët · Talía Boronat-Belda · Hilda Ferrero · Paloma Alonso-Magdalena · Karine Audouze · Spyros Karakitsios · Dimosthenis A. Sarigiannis
Frontiers in Toxicology
doi 10.3389/ftox.2026.1930835
Original Research
Published
The impact of zeaxanthin and lycopene on fatty acid beta-oxidation in isolated peroxisomes from frozen livers of obese rats
Lina Baz · Mona Al-Thepyani
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1906904
Original Research
Published
The role of goat FTO/IGF2BP1-mediated BCL11A m6A modification in intramuscular adipocyte differentiation
Wuqie QuBi · Yong Wang · Xin Li · Kehan Liu · Fangjun Lin · Yanyan Li · Jiani Xing · Youli Wang · Haitao Shi · Jiangjiang Zhu · Yaqiu Lin
Frontiers in Animal Science
doi 10.3389/fanim.2026.1875964
Review
Published
Effects of dietary C18 PUFA-rich oils on rumen function, growth performance, nutrient digestibility, ruminal lipid metabolism and milk and meat quality in ruminants: a review
Yufeng Wang · Yongli Wang · Zhihao Qiao · Mingshan Liu · Yuwei Yan · Xianxian Huo
Frontiers in Animal Science
doi 10.3389/fanim.2026.1913762
Original Research
Published
Bioinspired rhyolite particles as a functional material for lipid regulation in diet-induced obesity
Ahmad Bikharudin · Masahiro Okada · Satoshi Wakai · Ping-Chin Sung · Akihisa Otaka · Nutan Bhingaradiya · YuYang Jiao · Takuya Matsumoto
Frontiers in Food Science and Technology
doi 10.3389/frfst.2026.1964244
Correction
Published
Correction: Pregnancy and lactation exposure to bisphenol S induces ferroptosis via disrupted hepatic lipid metabolism in offspring mice
Mengfen Pan · Xinxin Guo · Caiyun Wei · Nuo Xu · Yan Su · Zhensong Ma · Huaicai Zeng
Frontiers in Toxicology
doi 10.3389/ftox.2026.1911506
Original Research
Published
Integrative genome-scale metabolic model of GABAergic neurons reveals metabolic signatures across the mild cognitive impairment – Alzheimer disease continuum
Andrea Angarita-Rodríguez · Johan H. Largo-González · Julián Pérez-Mejía · Daniel Balcazar · Viviana Vargas-López · Jason A. Papin · Andrés Pinzón · Janneth González
Frontiers in Systems Biology
doi 10.3389/fsysb.2026.1897648
Review
Published
Molecular mechanisms underlying drug resistance in protozoan parasites: emerging mechanisms and therapeutic perspectives
Kavithma Uduwela · Koshila Ranasinghe
Frontiers in Parasitology
doi 10.3389/fpara.2026.1934996
Original Research
Published
Rotenone-induced oxidative stress triggers peroxisomal alterations in BV-2 microglial cells
Alessio Valenza · Maurizio Muzzi · Francesca Rendina · Irene Montali · Daniele Pensabene · Anna Fracassi · Marco Segatto · Sandra Moreno
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1941513
Editorial
Published
Editorial: Environmental toxicity in metabolism
Tracey Woodlief
Frontiers in Toxicology
doi 10.3389/ftox.2026.1925459
Review
Published
From metabolism to neurodegeneration: how microglial functional reprogramming drives neurodegenerative diseases
Qiaoqiao Cui · Ke Zheng · Qiyun Liu · Lizhen Wang · Yixin Liu · Ruifang Bai · Wei Zhang · Junhong Guo · Xueli Chang · Juan Wang
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1921079
Review
Published
Microglia-mediated neuroinflammation in Alzheimer’s disease: mechanisms and emerging therapeutic targets
Lianjing Xu · Ying Zhang · Li Jiang · Jin Feng Xing · Jing Hu · Tianye Lan · Guang Ta
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1902577
Original Research
Published
Multi-omics reveals rhizosphere soil metabolismte-microbiota interactions in different varieties of sorghum under nutrient-deficient stress
Suxian Yan · Huiming Li · Yuzhong Cheng · Zuoyi Li · Hongmei Shi
Frontiers in Soil Science
doi 10.3389/fsoil.2026.1893513
Original Research
Published
Lipid-based protein sparing in juvenile whiteleg shrimp (Penaeus vannamei Boone, 1931) under reduced-protein diets and the limits of functional additives
Joren Alutaya · Brett Laudato · Jaynos R. Cortes
Frontiers in Aquaculture
doi 10.3389/faquc.2026.1908055
Original Research
Published
Genetic evidence for causal relationships between brain functional networks and domain-specific recovery after nondisabling ischemic stroke
Huan Cai · Zhenchun Huang · Jialin Liang · Hao Zhang · Zhonghua Liu
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10948
Original Research
Published
Comparative metabolomics provides insights into the metabolic reprogramming of the predatory Arma custos (Fabricius) during low-temperature storage
Yifan Dong · Xiaoyan Yuan · Zihan Shi · Yansong Xiao · Shaolong Wu · Can Wang · Lin Tan · Weiai Zeng · Yusheng Wang
Frontiers in Insect Science
doi 10.3389/finsc.2026.1820584
Review
Published
Sustainable flavor engineering in fermented foods: biochemical routes and technological applications of lactic acid bacteria
Debashree Borthakur · Bipin Kumar Sharma · Twesigye Duncan
Frontiers in Industrial Microbiology
doi 10.3389/finmi.2026.1834783
Review
Published
Stimulated Raman scattering microscopy: fundamentals, instrumentation, and chemical imaging applications
Fake Lu
Frontiers in Chemical Biology
doi 10.3389/fchbi.2026.1754307
Mini Review
Published
The choroid plexus- cerebrospinal fluid axis as a lifespan regulator of neural stem cells and circuit plasticity
Kelren S. Rodrigues · Rie Yamashita · Sayako Katada
Frontiers in Neural Circuits
doi 10.3389/fncir.2026.1818927
Review
Published
Oxidative stress in steroid-induced necrosis of femoral head: a review revealing new insights into pathogenic mechanisms
Yuansheng Wu · Ruixuan Ma · Hongjiang Jiang
Frontiers in Musculoskeletal Disorders
doi 10.3389/fmscd.2026.1788598
Review
Published
Acid sphingomyelinase inhibition as an antiviral strategy: mechanisms, functional inhibitors, and therapeutic potential against SARS-CoV-2 and beyond
Suvechha Bhandari · Abimbola O. Kolawole · Craig A. Rohan · Jeffrey B. Travers
Frontiers in Virology
doi 10.3389/fviro.2026.1791294
Original Research
Published
HIF1α reinforces PPARγ-dependent metabolic rechanneling to support lipid accumulation in adipocytes
Chaonan Zhu · Meiqian Wu · Minh Duc Pham · Yue Wang · Arka Provo Das · Yijie Mao · Peter Mirtschink · Ting Yuan · Jaya Krishnan
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2026.1716464
Epigenetics and Epigenomics
Published
Non-coding RNAs at the intersection of epigenetics and cancer metabolism
Nicolò Mangraviti · Serena Castelli
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1699969
Molecular Medicine
Published
Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD)
Claudia Theys · Tineke Vanderhaeghen · Evelien Van Dijck · Cedric Peleman · Anne Scheepers · Joe Ibrahim · Ligia Mateiu · Steven Timmermans · Tom Vanden Berghe · Sven M. Francque · Wim Van Hul · Claude Libert · Wim Vanden Berghe
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2023.1283170