Articles

Showing 59 articles

• Original Research

  Published 12 October 2026

  Fibrinolytic suppression and increased uterine artery resistance are associated with embryo resorption in DBA/2 mated CBA/J mice

  Youchen Liu · Jingjing Wang · Boning Huang · Ping Tang · Fangle Liu · Yuying Zheng · Yilin Li · Huiyi Xie · Liuqing Lin · Xinrong Yang · Xiubing Zhang · Jie Gao · Baoqin Lin

  Frontiers in Physiology

  doi 10.3389/fphys.2026.1942168

• Original Research

  Published 9 October 2026

  Clinical challenges in vaccine and monoclonal antibody development against ESCAPE pathogens: insights from EMA scientific advice procedures

  Igor Stojkov · Linda Marchioro · Isabelle Bekeredjian-Ding · Benjamin Hofner

  Frontiers in Medicine

  doi 10.3389/fmed.2026.1931144

• Hypothesis and Theory

  Published 9 October 2026

  Based on the skeletal-muscle dual stem cell chemotaxis and bidirectional differentiation mechanism to reinterpret the “sinew-bone interdependence” theory

  Jiahao Dong · Tao Chen

  Frontiers in Cell and Developmental Biology

  doi 10.3389/fcell.2026.1869812

• Original Research

  Published 8 October 2026

  Availability and reimbursement of fixed-dose combination medicines for hypertension treatment in Central and Eastern Europe

  Rafał Nowak · Przemysław Holko · Iris Hoxha · Alexandra Savova · Pero Draganić · Jana Skoupa · Agnes Männik · Zoltán Kaló · Arturs Praskilevics · Kristina Garuoliene · Ljubica Shuturkova · Elena Chitan · Natasa Duborija-Kovacevic · Michał Owca · Ioana Bianchi-Manaila · Nikola Stefanovic · Tomas Tesar · Tamás Ágh · Paweł Kawalec

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1889485

• Systematic Review

  Published 8 October 2026

  Selected traditional Chinese medicines for treating amyotrophic lateral sclerosis: a Bayesian network meta-analysis based on randomised controlled trials

  Chen Shen · Xiao-Ti Wu · Heng Yin · Jing-Ling Zuo · Chen-Hao Zhang · Feng Cao · Ying Zhang · Zi-Yu Tian · Nicola Robinson · Jian-Ping Liu

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1706211

• Review

  Published 5 October 2026

  Plant mediated nanoparticles from Cissus quadrangularis L.: a comprehensive review on antimicrobial resistance, biological activities and therapeutic applications

  K. Vinoth · S. Ramesh Kumar

  Frontiers in Nanotechnology

  doi 10.3389/fnano.2026.1945218

• Review

  Published 5 October 2026

  Advances and applications of engineered protein therapeutics and their role in precision medicine

  Wadha Aldossary · Nada Alqahtani · Layla Asiri · Noora Alkhurayef · Samar Alagl · Sana Alturki · Duha Saad · Mashael Al Yahya · Samah Al-Harthi

  Frontiers in Bioengineering and Biotechnology

  doi 10.3389/fbioe.2026.1857362

• Original Research

  Published 2 October 2026

  Prevalence and associated factors of catastrophic health expenditure among adults with chronic pain in an urban slum of Delhi: a community-based cross-sectional study

  Shivani Rao · Kinshuk Gupta · Priyanka Aggarwal · Amod Laxmikant Borle · Nandini Sharma · Mongjam Meghachandra Singh

  Frontiers in Health Services

  doi 10.3389/frhs.2026.1933208

• Hypothesis and Theory

  Published 28 September 2026

  A pragmatic workflow for integrating large language models into toxicological risk assessment

  Arianna Bassan · Alexander Amberg · Maria Letizia Barreca · Paul M. Bradley · Frank Bringezu · Joyce De Paula Souza · Corinne Guicheney · Elena Lo Piparo · Simona Kovarich · Andrey Massarsky · Georgia Maundrill · Lance Molnar · Cristina Parenti · Patricia Parris · Manuela Pavan · John F. Reichard · Ron Steigerwalt · Olga Tcheremenskaia · Kenneth Unice · Christopher J. Waine · Geraldine Whelan · Angela White · Glenn J. Myatt

  Frontiers in Toxicology

  doi 10.3389/ftox.2026.1877128

• Original Research

  Published 25 September 2026

  Quality by design driven development of a Monteverdia ilicifolia herbal medicine: from plant to granules

  Alberto Araujo de Caux · José Cláudio Klier Monteiro Filho · Ruan Barbosa da Silva e Medeiros · Marili Villa Nova Rodrigues · Marcos Nopper Alves · Marcus Bruno Soares Forte · Maria Isabel Rodrigues · Rodney Alexandre Ferreira Rodrigues

  Frontiers in Natural Products

  doi 10.3389/fntpr.2026.1887810

• Review

  Published 23 September 2026

  Paraprobiotics and postbiotics: from mechanistic evidence to food applications and clinical translation

  Diana Pasarin · Iuliu-Gabriel Malos · Andra-Ionela Ghizdareanu · Antonia Gabriela Malos · Daniela Ianitchi · Gabriela Malos · Noemi Elena Virna · Catalin Bogdan Matei · Alina Alexandra Dobre · Luiza Capra · Georgeta Ramona Ivan · Bogdan Frunzareanu

  Frontiers in Food Science and Technology

  doi 10.3389/frfst.2026.1965558

• Review

  Published 21 September 2026

  Transport phenomena in polymeric nanoparticle drug delivery systems: linking soft-matter design to biological performance

  Samson Oluwabamise Dada · Adegboyega Daniel Osifuwa · Ifeoluwa Deborah Boyede

  Frontiers in Soft Matter

  doi 10.3389/frsfm.2026.1931284

• Hypothesis and Theory

  Published 18 September 2026

  Authentic content as an effective mechanism for embedding patient voices in health innovation: a hypothesis and conceptual framework

  Rohin Malhotra

  Frontiers in Health Services

  doi 10.3389/frhs.2026.1833920

• Review

  Published 18 September 2026

  Implementation of the World Health Organization’s Package of Essential Noncommunicable Disease Interventions: an overview of reviews

  Hongyi Xu · Yiming Hu · Maoshu Li · Jing Yang · João Joaquim Breda · Jing Wu · Alarcos Cieza

  Public Health Reviews

  doi 10.3389/phrs.2026.1609607

• Review

  Published 18 September 2026

  Novel bioactive compounds in the treatment of osteoporosis: chemistry-driven discovery from preclinical validation to clinical translation

  Honghui Fan · Songtao Jin

  Frontiers in Chemistry

  doi 10.3389/fchem.2026.1917991

• Original Research

  Published 14 September 2026

  Factors associated with common mental disorder symptoms and lived experiences among adults with hypertension in Nepal: a mixed-methods study

  Lisasha Poudel · Binita Acharya · Bipsana Shrestha · Shreya Shrestha · Archana Shrestha · Buna Bhandari · Brandon A. Kohrt · Dristy Gurung · Sauharda Rai

  Frontiers in Epidemiology

  doi 10.3389/fepid.2026.1769884

• Original Research

  Published 11 September 2026

  Cohort retention in seasonal malaria chemoprevention: an analysis of magnitude and associated factors in Northern Bahr el Ghazal, South Sudan

  Francis Okot · Norman Aweno · Ebenezer C. Ikechukwu · Abubaker Rom · Gerald Kabuye · Jamshed Khan · Anthony Kirabira · Atemthi Dhieu Dau · Amanya Jacob · Ezbon WApary · Simon Peter Katongole · Denis Mubiru · Chukwudi A. Nnaji

  Frontiers in Malaria

  doi 10.3389/fmala.2026.1913848

• Review

  Published 25 August 2026

  Translational advances in diabetic nephropathy management: integrating nanoformulation-based drug delivery systems

  Mohd Danish Ansari · Ashish Vishwakarma · Md Quamuddin · Mansi Aggarwal · Hashim Khan · Muhammad Fauzi Abd Jalil · Syed Mahmood · Adil Farooq Wali · Sirajunisa Talath · Mohamed El-Tanani

  Frontiers in Medical Technology

  doi 10.3389/fmedt.2026.1951734

• Perspective

  Published 21 August 2026

  Holding the line against artemisinin partial resistance in Africa: the case for preemptive treatment policy

  Shyamkumar Sriram

  Frontiers in Malaria

  doi 10.3389/fmala.2026.1916099

• Original Research

  Published 19 August 2026

  Detection of TR34/L98H pan-azole-resistant Aspergillus fumigatus in poultry farm environments

  Bianca Gomes · Marta Dias · Renata Cervantes · Lídia Gonçalves · Elisabete Carolino · Miguel J. N. Ramos · Mónica Nunes · Ricardo Dias · Carla Viegas

  Frontiers in Fungal Biology

  doi 10.3389/ffunb.2026.1858050

• Mini Review

  Published 18 August 2026

  Unravelling biofilm complexity: a regulatory science perspective

  Leanne M. Cleaver · Carmen H. Coxon

  Frontiers in Bacteriology

  doi 10.3389/fbrio.2026.1886299

• Mini Review

  Published 20 July 2026

  Nanosystems for delivery of indolicidin peptide

  José Gregorio Martín Bedoya · Katia Conceição

  Frontiers in Medical Technology

  doi 10.3389/fmedt.2026.1845120

• Perspective

  Published 16 June 2026

  From community to policy: a frontline model for dementia assessment and brain health

  Kyle DeDecker · Ngozi Iroanyah · Adam Morrison · Julie Datta · Ibukun-Oluwa Omolade Abejirinde · Caitlin R. Siu · Christina Stergiou-Dayment · Shawn Paron · Christa M. Studzinski

  Frontiers in Dementia

  doi 10.3389/frdem.2026.1821709

• Original Research

  Published 3 June 2026

  Antiparasitic triterpenic ester and ursolic acid lipid nanocapsule design, cytotoxicity, and permeability evaluation for oral delivery

  Laura Schioppa · Cecilia Bohns Michalowski · Lucia Mamede · Romano Terrasi · Marie-France Hérent · Giulio G. Muccioli · Raphaël Frédérick · Michel Frederich · Ana Beloqui · Joelle Quetin-Leclercq

  Frontiers in Drug Delivery

  doi 10.3389/fddev.2026.1846904

• Community Case Study

  Published 29 May 2026

  Strengthening pharmacovigilance and regulatory capacity in Southern Africa (SPaRCS): achievements, experiences and lessons learned from a participatory action learning project

  Michelle Viljoen · Star Khoza · Mukesh Dheda · Libert Chirinda · Frieda Shigwedha · Anna Shimbulu · SipheSihle Nhlabatsi · Nomsa Shongwe · Albert Figueras · Raffaella Ravinetto · Hazel Bradley

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2026.1765077

• Perspective

  Published 29 May 2026

  The promise and peril of mirror bacteria

  Kyna Rigouts · Gregor Becker

  Acta Biochimica Polonica

  doi 10.3389/abp.2026.16673

• Original Research

  Published 20 May 2026

  Empirical antibiotic prescribing in COVID-19 patients: patterns and predictors in a resource-constrained Central Indian setting

  Manju Purohit · Deepali Pathak · Devendra Baghel · Jitendra Jat · Ashish Sharma · Ashish Pathak

  Frontiers in Antibiotics

  doi 10.3389/frabi.2026.1826199

• Review

  Published 11 May 2026

  Sequence-dominant protein therapeutics: mechanistic foundations for efficient biologics development

  Sarfaraz K. Niazi

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1781560

• Original Research

  Published 11 May 2026

  Outcomes of post-approval non-interventional safety studies in pregnancy: wide variation demonstrates need for further standardization

  Stacy Chen · Sarah C. MacDonald

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2026.1805759

• Review

  Published 8 May 2026

  Gold nanomaterials in the diagnosis and treatment of kidney diseases: from fundamental transport mechanisms to clinical translation prospects

  Haicheng Liu · Jingyi Zhao · Jiankun Zheng · Kecheng Lou · Yuwei Zhong

  Frontiers in Nanotechnology

  doi 10.3389/fnano.2026.1846780

• Original Research

  Published 7 May 2026

  Global pharmacovigilance reporting: comparative analysis of adverse event obligations across five major regulatory authorities

  Carlos G. Bernaus · Maria Lilia Bournissen

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2026.1821686

• Original Research

  Published 16 April 2026

  Investigation on partial acidulation of rock phosphate using acetic acid and acidic calcium phosphate solutions

  Youness Sedki Alaoui · Yuriy Sakhno · Pavlo Ivanchenko · Mohamed Hafidi · Martin Jemo · Deb P. Jaisi

  Frontiers in Chemical Engineering

  doi 10.3389/fceng.2026.1779902

• Review

  Published 15 April 2026

  Analytical similarity as the primary determinant of monoclonal antibody development: toward evidence-efficient regulatory frameworks

  Sarfaraz K. Niazi

  Frontiers in Drug Delivery

  doi 10.3389/fddev.2026.1801236

• Correction

  Published 18 March 2026

  Correction: Colour of medicines and children’s acceptability: What children think of the colour of oral dosage forms?

  Frontiers Production Office

  Frontiers in Drug Delivery

  doi 10.3389/fddev.2026.1818974

• Original Research

  Published 9 March 2026

  Federating AI-related regulations for human therapeutics: an AI-enabled, continuously updating regulatory intelligence system

  Rominder Singh · Mukesh Pareek · Michael Prokle · Eduardo Sanchez · Uwe Hohgrawe · Jared R. Auclair

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2026.1718379

• Brief Research Report

  Published 26 February 2026

  Retrospective observational study of Kampo medicines for suppressing the side effects of endocrine therapy in the treatment of breast cancer: a pilot study

  Shin Takayama · Atsuhiko Furuta · Haruhiko Shindo · Ryutaro Arita · Kaolu Sato · Tadashi Ishii

  Frontiers in Cancer Control and Society

  doi 10.3389/fcacs.2026.1677567

• Original Research

  Published 13 February 2026

  Colour of medicines and children’s acceptability: What children think of the colour of oral dosage forms?

  Elisa Alessandrini · Sveinbjorn Gizurarson · Jennifer Walsh · Roy Turner · Daniel Schaufelberger · Sonia Iurian · Hannah Batchelor · Sandra Klein · Begonya Nafria · Pamela Dicks · Segolene Gaillard · Axel R. Franz · Jasmin Albano · Aleksander Wisniewski · Charlotte Vermehren · Christina Gade · Jon Traerup Andersen · Catherine Tuleu

  Frontiers in Drug Delivery

  doi 10.3389/fddev.2026.1744120

• Mini Review

  Published 11 February 2026

  Standardization of canine infections for the development of antileishmanial drugs

  A. I. Olías-Molero · M. J. Corral-Caridad · M. D. Jiménez-Antón · M. Mateo-Barrientos · J. Carrión · J. J. Torrado · J. M. Alunda

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1754269

• Review

  Published 12 January 2026

  Skin wound healing part II: from traditional cataplasm to advanced wound dressings

  Amanda Guadalupe Romero · Andrea Paola Rodriguez · Silvia Noemi Kozuszko · Kenichi Nagano · Carmelo José Felice · Naoki Katase

  Frontiers in Soft Matter

  doi 10.3389/frsfm.2025.1681598

• Review

  Published 18 December 2025

  A narrative review on the environmental impact of medicines: from water analysis and in vivo studies to prescribing appropriateness, based on European and Italian legal frameworks

  Irene Cristini · Elisabetta Poluzzi · Federica Soardo · Salvatore Crisafulli · Stefano Polesello · Ursula Kirchmayer · Marco Milani · Francesca Russo · Michele Nicoletti · Giovanna Scroccaro · Paola Deambrosis · Shima Tavakolian Haghighi · Jacopo Grisotto · Ugo Moretti · Giovanna Paolone · Gianluca Trifirò

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2025.1681648

• Review

  Published 11 December 2025

  Skin wound healing part I: ancestral and modern medicines for the development of new technologies

  Andrea Paola Rodriguez · Amanda Guadalupe Romero · Silvia Noemi Kozuszko · Lucca Comotti · Kenichi Nagano · Carmelo José Felice · Naoki Katase

  Frontiers in Soft Matter

  doi 10.3389/frsfm.2025.1683717

• Review

  Published 1 December 2025

  The use of observed-to-expected analyses as a signal detection tool in COVID-19 vaccine safety surveillance: lessons learned from an industry perspective

  Laurence Serradell · Antonella Fretta · Jenny Nachbar · Jill Dreyfus · Diana Garofalo · Arianna Lucini · Susan Mather · Daina Esposito · Anne-Laure Chabanon · Vincent Bauchau · Sarah Sellers

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2025.1650992

• Policy and Practice Reviews

  Published 26 November 2025

  Post-approval safety studies of vaccines in pregnancy: available regulatory guidance and next steps towards the more efficient generation of safety evidence

  Sarah C. MacDonald · Adrienne P. Guignard · Flor M. Munoz · Eileen O. Dareng · Kourtney J. Davis · Marina Amaral de Avila Machado · Shahar Shmuel · Laura Taddei · Lydie Marcelon

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2025.1648854

• Review

  Published 26 November 2025

  Discrepancies in regulations in post-marketing safety surveillance of drug-device combination products in the EU and US: a review

  Joan D’souza · Mukesh Nandave · Ruth Blöchlinger

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2025.1609455

• Impact Journals

  Published 7 October 2025

  Precision cardiovascular medicine: shifting the innovation paradigm

  Masanori Aikawa · Abhijeet R. Sonawane · Sarvesh Chelvanambi · Takaharu Asano · Arda Halu · Joan T. Matamalas · Sasha A. Singh · Shizuka Uchida · Elena Aikawa · Alex Arenas · Jean-Luc Balligand · Chiara Giannarelli · Calum A. MacRae · Neil V. Morgan · Cécile Oury · Hendrik Tevaearai Stahel · Joseph Loscalzo

  Frontiers in Science

  doi 10.3389/fsci.2025.1474469

• Drug Safety and Regulation

  Published 10 September 2025

  Identifying regulatory outcomes of Non-interventional Post-Authorisation Safety Studies (PASS) in the European repository of studies using publicly available information

  M. F. Almas · A. Girardi · S. Crisafulli · K. Gvozdanovic · K. M. Hakkarainen · G. Hyeraci · W. E. Hoogendoorn · B. Rillmann · G. Roberto · G. Vitturi · G. Trifirò · ENCePP WG3

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2025.1574430

• Malaria

  Published 28 August 2025

  Knowledge, beliefs and adherence to antimalarial medications among patients in the Ga East Municipality of Ghana

  Michelle Akua Amoako · Victor Collins Wutor · Benoit Banga N’guessan

  Frontiers in Malaria

  doi 10.3389/fmala.2025.1582682

• Natural Products

  Published 22 August 2025

  A review on integrative approaches in oncology: bridging ayurvedic medicine and modern cancer therapeutics

  Sudhanshu Kumar Jha · Neha Singh · Ozasvi R. Shanker · Ishika Antil · Jaydeep Singh Baghel · Vittal Huddar · Richa Tripathi

  Frontiers in Natural Products

  doi 10.3389/fntpr.2025.1635197