PerspectivePublished 12 October 2026From macrofungal polysaccharides to precision microbial immunotherapy: reprogramming the tumor microenvironment through immunometabolic and gene-regulatory pathwaysKingsley Excel Dunga · Sylvester Chibueze Izah · Ebinyo Rebecca Aseibai · Matthew Chidozie Ogwu · Vivian Ibienebakabobo Promise · Nsikak Godwin Etim · Irene Nneka OhanusiFrontiers in Oncologydoi 10.3389/fonc.2026.1966586