Original ResearchPublished 16 September 2026Identification of natural TLR4 modulators through network pharmacology and molecular modeling in SARS-CoV-2 Acinetobacter baumannii co-infectionMebarka Ouassaf · Shafi Ullah Khan · Kannan R. R. Rengasamy · Nada S. Alhaggass · Bader Y. AlhatlaniFrontiers in Chemistrydoi 10.3389/fchem.2026.1916568
Original ResearchPublished 23 July 2026ALS-associated FUS mutations induce site-specific alterations in conformational dynamics and molecular interactionsChristodoulos Amourgianos · Themis P. Exarchos · Panagiotis Vlamos · Marios G. KrokidisFrontiers in Chemical Biologydoi 10.3389/fchbi.2026.1851848
Specialty Grand ChallengePublished 16 February 2026Revisiting the grand challenges: the road travelled and ahead at the frontiers of computer-aided drug designJosé L. Medina-FrancoFrontiers in Drug Discoverydoi 10.3389/fddsv.2026.1780834
Original ResearchPublished 10 November 2025New analogs of 5-substituted-2(1 H )-pyridone containing of natural amino acids as potential drugs in idiopathic pulmonary fibrosis. Investigation in silico and preliminary in vitroKrystyna Dzierzbicka · Maria Skrzypkowska · Monika Gensicka-Kowalewska · Mateusz Daśko · Bartosz SłomińskiActa Biochimica Polonicadoi 10.3389/abp.2025.15218
