Review
Published
Application of large language models in early screening of Alzheimer’s disease: a scoping review
Jianan Tian · Weidong Huang · Yongmei Wen · Yifan Liang
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1906641
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Showing 114 articles
Review
Published
Digital biomarkers derived from wearable and portable devices in prodromal Parkinson’s disease and at-risk populations: a scoping review
Ting Yu · Qian Wang · Mingxia Pan · Yuanfang Xiong · Shiya Hu · Yiping Deng · Lingyu Kuang · Hanjiao Liu
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1850991
Original Research
Published
Explainable machine learning integrating CT-derived intratumoral heterogeneity for histological subtype prediction in pure ground-glass lung adenocarcinoma: multicenter validation and transcriptomic characterization
Ying Deng · Jiajun Liu · Dinghua Li · Bingyi Zhang · Bin Xiang · Wanyin Qi · Sanhong Zhang
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1958127
Original Research
Published
Chronic disease count and fall-related characteristics among community-dwelling older adults: a cross-sectional study of recurrent falls and fall timing
Yu Chen · Junliang Zhou · Yuanyuan Cai · Jierong Li
Frontiers in Public Health
doi 10.3389/fpubh.2026.1882689
Review
Published
Multi-omics insights into immune dysregulation and candidate biological programs in kawasaki disease: toward precision immunomodulation
Yun Han · Jiaying Liu · Chengxu Song · Li Fu · Yu Gu · Yu Zeng · Zhenzhuang Zou
Frontiers in Pediatrics
doi 10.3389/fped.2026.1960681
Original Research
Published
Comparative analysis of three-year outcomes of different interbody fusion approaches for grade I-II lumbar spondylolisthesis with spinal stenosis
Jian Luo · Li-Hua Shen · Teng-Fei Zhao · Chang-Shen Bao · Zhi-Chao Gao · Yong-Jun Meng · Guo-Fu Zheng
Frontiers in Surgery
doi 10.3389/fsurg.2026.1847229
Original Research
Published
Age as a significant prognostic factor in patients meeting the global ARDS definition but not the Berlin definition
Pan Pan · Jin Chen · Tiantian Zhang · Cheng Haibo · Zhang Wanyi · Xiaobo Han · Han Xinjie · Hu Xingshuo · Yang Qingyun · Gu Hongjun · Liu Yuhong · Lixin Xie
Frontiers in Medicine
doi 10.3389/fmed.2026.1929746
Original Research
Published
Incremental prognostic value of the T-helper 1/T-helper 2 immune phenotype and 72-h change in sequential organ failure assessment for in-hospital mortality in sepsis with and without type 2 diabetes: a retrospective two-cohort study
Dongxu Pan · Zongnan Lv · Jiayan Li · Bo Zhang · Feifei Xu · Wuxiang Huang · Wei Chen · Xuejun Mo
Frontiers in Medicine
doi 10.3389/fmed.2026.1911557
Original Research
Published
Multi-sequence magnetic resonance imaging radiomics integrated with clinical features predicts pelvic lymph node metastasis in cervical cancer: a retrospective-prospective cohort study
Wanqing Gong · Xiaoyi Liu · Mengli Wang · Xiaowen Hu · Guangping Yan · Kun Liu · Yongxin Li · Tingting Zhang
Frontiers in Medicine
doi 10.3389/fmed.2026.1910248
Systematic Review
Published
Imaging biomarkers related to 18F-FDG PET/CT for predicting microvascular invasion in hepatocellular carcinoma: a systematic review and meta-analysis
Zhigang Li · Ke Gong · Ning Liu
Frontiers in Oncology
doi 10.3389/fonc.2026.1948193
Original Research
Published
Development and validation of a nomogram for predicting chest drainage after CT-guided percutaneous lung biopsy: a multicenter retrospective study
Haiyu Liang · Yanyan Tang · Weicong Kang · Yanfeng Zhao
Frontiers in Oncology
doi 10.3389/fonc.2026.1930072
Perspective
Published
Revisiting proton therapy for adenoid cystic carcinoma: a case worth making
Astha Rohit · Adam Holtzman · James Bates · Scott Lester · Roi Dagan · Barbara Vischioni · Ester Orlandi · Maria Bonora · Amy Tien Yee Chang · Rohan Deraniyagala · Martin Bues · Steven Frank · Samir H. Patel · Atsushi Musha · Tatsuya Ohno · Nancy Lee · Lisa McGee
Frontiers in Oncology
doi 10.3389/fonc.2026.1979803
Original Research
Published
Early dynamics of eosinophils and the neutrophil-to-lymphocyte ratio are associated with severe immune-related adverse events during nivolumab therapy for metastatic renal cell carcinoma
Ondřej Fiala · Jan Králíček · Jindřich Kopecký · Michal Vočka · Tomas Buchler · Hana Študentová · Jana Obertová · Beáta Rondzíková · Martin Matějů · Dominik Šafčák · Matej Hrnčár · Peter Priester · Martina Spisarová · Anežka Zemánková · Radka Lohynská · Michaela Tkadlecová · Lucie Grmelová · Petr Stránský · Bohuslav Melichar · Patrik Palacka · Alexandr Poprach
Frontiers in Immunology
doi 10.3389/fimmu.2026.1944728
Systematic Review
Published
The application of square-stepping exercise in patients with stroke: a scoping review
Yali Yan · Juan Xu · Jiaxin Yao · Yuanyuan Liu · Mengdan Li · Xinxin Geng
Frontiers in Neurology
doi 10.3389/fneur.2026.1952887
Original Research
Published
Robot-assisted aspiration improves survival over conservative treatment in critical primary brainstem hemorrhage: a multicenter, volume-stratified cohort study
Haoming Guo · Xiaoliang Wang · Jialong Li · Shuoxuan Che · Qingyang You · Shang Gao · Lifeng Wu · Juncang Zhao · Zhiqiang Wang · Tao Li · Hailong Du · Xiaosong Liu · Lei Zhao · Xianming Wang · Shan Zhang · Wei Tian · Jianliang Wu
Frontiers in Neurology
doi 10.3389/fneur.2026.1954969
Original Research
Published
Long-term post-trial extension of osilodrostat therapy in selected Canadian patients with Cushing disease from the LINC 3 and LINC 4 programs
Luciana Martel-Duguech · Ghislaine Houde · Constance Chik · Syed Ali Imran · André Lacroix
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1902818
Clinical Trial
Published
Efficacy of Huangbai liniment for diabetic foot ulcers with multidrug-resistant organism infection: a randomized controlled multicenter trial
Ning Wang · Gang Wang · Min Zhou · Keren Zhang · Tong Zhou · Xuewan Wang · Guangyao Yang · Lijuan Deng · Tianyi Huang · Shang Ju
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1926211
Original Research
Published
Spondylodiscitis in a tuberculosis-endemic setting in Somalia: epidemiological, clinical, radiological, and outcome findings from a retrospective study
Hussein Salad Yusuf · Abdirisak Ali Abukar · Mohamed Said Adan · Abdiaziz Siad Mohamed · Zakariye Yusuf Mohamed · Mustaf Abdi Ulusow · Mohamed Osman Dahir Alasow · Abdiwahid Ahmed Ibrahim · Naimo Awil Dahir
Frontiers in Tuberculosis
doi 10.3389/ftubr.2026.1971442
Original Research
Published
Admission platelet-to-hemoglobin ratio and 1-year outcomes after percutaneous coronary intervention: a multicenter registry cohort study
Jeong Tae Byoun · Donghyeon Joo · Sungho Jo · Jae Young Cho · Kyeong Ho Yun
Frontiers in Cardiovascular Medicine
doi 10.3389/fcvm.2026.1981126
Original Research
Published
Clinical reasoning in canine meningoencephalitis of unknown origin and glioma: the role of signalment, history and neurological examination
Franziska Spohn · Samira Abani · Peter J. Dickinson · Karen M. Vernau · Christine M. Toedebusch · Kevin D. Woolard · Andreas Beineke · Holger A. Volk · Jasmin N. Nessler
Frontiers in Veterinary Science
doi 10.3389/fvets.2026.1920683
Original Research
Published
Laboratory-derived inflammatory–nutritional exploratory phenogroups and their associations with functional limitation and 30-day same-center all-cause unplanned readmission in patients with heart failure
Yilian Zhang · Xu Zhang · Hongbin Song · Qiyu Hu · Jingzhu Nan
Frontiers in Nutrition
doi 10.3389/fnut.2026.1985953
Systematic Review
Published
Extracorporeal kidney support in neonates and infants: therapeutic perspectives and outcomes in multiple organ dysfunction syndrome—a structured narrative review
Gulmira Zhauarova · Dinagul Baesheva · Gulnur Nadirbekova · Kamilla Rakhimova · Bolat Bekishev · Talgat Ibrayev
Frontiers in Pediatrics
doi 10.3389/fped.2026.1739965
Original Research
Published
Radiomics-based interpretable machine learning model for identifying high-risk patients with small bowel obstruction: a multicenter study
Guozheng Zhang · Xiaohui Liu · Weitao Huang · Xisong Zhu · Cong Xia · Hua Xia · Yuguo Wei · Xiaowei Han · Danqiong Wang
Frontiers in Medicine
doi 10.3389/fmed.2026.1848334
Original Research
Published
Development and temporal validation of a calibrated machine learning model for in-hospital blood culture positivity using routine clinical data
Tao Huang · Zhenzhen Tan · Longyang Jiang · Xuping Yang · Shurong Wang · Yilan Huang
Frontiers in Medicine
doi 10.3389/fmed.2026.1956921
Original Research
Published
Identification and validation of early vital sign trajectory subphenotypes for risk stratification in sepsis-associated liver injury: a multicenter retrospective cohort study
Weihang Wang · Jing Ma · Bingqing Wang · Jiayang Wang · Zexi Zang · Qiyao Liu · Zhi Gao · Wei Chen · Yuxin Deng · Zhiqing Zhang · Yongfang Jiang
Frontiers in Medicine
doi 10.3389/fmed.2026.1835574
Original Research
Published
Aortic versus non-aortic cryopreserved allograft and donor-specific outcome: a retrospective observational study
Matthias Buerger · Anna Schneider · Franz Bartholomé · Philipp Pauli · Alexandra Bonietzki · Thorben Michaelis · Melanie Rusch · Grischa Hoffmann · Rene Rusch · Sebastian Kapahnke
Frontiers in Surgery
doi 10.3389/fsurg.2026.1957142
Review
Published
Free flap selection strategies and advances in facial soft tissue defect reconstruction
Junzhi Zhao · Xing He · Kangcha Chen · Jianhui Zhou · Guoqiang Li · Jialu Liu
Frontiers in Surgery
doi 10.3389/fsurg.2026.1912392
Original Research
Published
Comparison of feasibility, inter-instrument agreement, and prognostic value of four frailty assessment instruments in geriatric colorectal cancer patients: a 3-year multicenter prospective cohort study
Lei Ma · Feiyu Shi · Chenhao Hu · Kexue Wang · Lei Zhang · Penghong Qu · Junjun She
Frontiers in Oncology
doi 10.3389/fonc.2026.1878424
Review
Published
From image biomarkers to treatment decisions: multimodal AI and clinical translation in gynecologic oncology
Mohamad Bakir · Mohammad Khaldoun Al Masri · Yousef Mushtaha · Narmeen Shaikh · Mohammed Raddaoui · Khalid Said Mohammad
Frontiers in Oncology
doi 10.3389/fonc.2026.1960963
Original Research
Published
Research trends and emerging topics in gut microbiota-derived metabolites and diabetic kidney disease: a multi-database bibliometric analysis (2014–2025)
Xinyu Yang · Xiangning Huang · Yaru Shi · Yunfeng Yu · Rong Yu
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1967850
Correction
Published
Correction: A multicenter, randomized, double-blind, double-simulated, positive drug parallel-controlled clinical trial to evaluate the efficacy and safety of Xiao’er Fengreqing oral liquid in the treatment of acute pharyngitis/ tonsillitis in children
Lei Shi · Kai Liu · Yike Song · Chunsun Mu · Chunxiang Wang · Yongchao Jiang · Robb Russell · Yaqian Wen · Rihe Liu · Jianping Liu · Huilan Liu · Zhaolan Liu
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1988967
Mini Review
Published
Saliva-based genomic signatures for early detection of oral squamous cell carcinoma: the state and perspectives of translation
Hiren Hansraj Patadiya · Satya Upadhyayula · Vrunda T. Adeshara
Frontiers in Genetics
doi 10.3389/fgene.2026.1831378
Study Protocol
Published
Effect of epidural spinal cord stimulation combined with personalized neurorehabilitation in chronic motor-complete spinal cord injury: study protocol for the phase II single-arm feasibility RESTORES (RESToration Of Rehabilitative function with Epidural spinal Stimulation) trial
Kai Rui Wan · Zhi Yan Valerie Ng · Seng Kwee Wee · Fatimah Misbaah · Wen Li Lui · Min Wee Phua · Tegan Plunkett · Neethu Robinson · Aung Aung Phyo Wai · Cuntai Guan · Ananda Sidarta · Rosa Qi Yue So · Brian Premchand · Kezia Susanto · Luca Cocchi · Seyed Ehsan Saffari · Rui Xin Justin Ker · Wai Hoe Ng
Frontiers in Neurology
doi 10.3389/fneur.2026.1967078
Original Research
Published
Long-term survival after transcatheter aortic valve implantation in nonagenarian patients: a multicenter real-world study
Gianluca Pagnoni · Marco Loffi · Dalia Caleffi · Susan Darroudi · Giuseppe Masaracchia · Benedetta Frassoni · Francesco Marangi · Sophia di Michele · Davide Gabbieri · Luciano Losi · Alberto Monello · Fabio Alfredo Sgura · Salvatore Arrotti · Rosario Rossi · Daniele Iaccarino · Marco Ruozzi · Vincenzo Guiducci · Filippo Luca Gurgoglione · Giorgio Benatti · Luigi Vignali · Giampaolo Niccoli · Giuseppe Boriani · Daniela Aschieri · Francesca Coppi
Frontiers in Cardiovascular Medicine
doi 10.3389/fcvm.2026.1945453
Original Research
Published
Knowledge, attitudes, and practices of emergency nurses regarding sepsis nutritional management: a multicenter cross-sectional study
Lin Xiao · Weijia Pei · Huijun Zhu
Frontiers in Nutrition
doi 10.3389/fnut.2026.1933045
Original Research
Published
Head-to-head comparison of glucose-to-albumin ratio against five albumin-derived indices for predicting 28-day ICU mortality in critically ill patients with spontaneous intracerebral hemorrhage: a multicenter retrospective study
Fangbin Hao · Luokai Huangfu · Wenxuan Li · Yanteng Li · Rui Hui · Caihong Sun · Meijing Liu · La Shi · Shenghan Xu · Gang Cheng · Jianning Zhang
Frontiers in Nutrition
doi 10.3389/fnut.2026.1909009
Original Research
Published
Comparison of an automated and paper bladder diary in pediatric patients: mixed-methods, randomized crossover study
Lola Bladt · An Bael · Nathalie Segers · Karolien De Moerloose · Katrien Klockaerts · Hendrik-Jan Florin · Lukas Van Campenhout · Stefan De Wachter · Alexandra Vermandel · Karen De Baets · Gunter De Win
Frontiers in Pediatrics
doi 10.3389/fped.2026.1959698
Systematic Review
Published
Treatment of idiopathic pulmonary hemosiderosis in children: a systematic review
PengCheng Liu · ZhiChao Lei
Frontiers in Pediatrics
doi 10.3389/fped.2026.1982437
Original Research
Published
Stepwise surgical management of rectal foreign bodies: a multicenter operative case series and systematic review
In Kyu Park · Kyung Uk Jung · Songsoo Yang · Sung Ryol Lee · Joosung Park · Hyung Ook Kim · Hungdai Kim · Jaemin Jo · Joon Young Choi · Sung Yoon Jang · Hongki Gwak · Weon Young Chang · Ho-kyung Chun · Donghyoun Lee
Frontiers in Surgery
doi 10.3389/fsurg.2026.1933279
Mini Review
Published
Cenobamate in super-refractory status epilepticus: current evidence from a patient-level synthesis
Giovanni Falcicchio · Teresa Francavilla
Frontiers in Neurology
doi 10.3389/fneur.2026.1961349
Review
Published
Digital health meets Parkinson’s disease: a bibliometric exploration of wearable sensors research and emerging frontiers (2005–2026)
Lan Xiong
Frontiers in Neuroinformatics
doi 10.3389/fninf.2026.1937585
Original Research
Published
Higher fibrosis-4 index is associated with 2-year cardiovascular events in Vietnamese adults with type 2 diabetes mellitus: a prospective cohort study
Quoc Bao Vu · Hong Minh Cong Vo · Xuan Linh Tran · Tuan Vu Nguyen · Thi Khanh Tuong Tran
Frontiers in Gastroenterology
doi 10.3389/fgstr.2026.1973311
Original Research
Published
Knowledge and practices regarding postoperative neonatal pain assessment among healthcare professionals in Kinshasa: a multicenter cross-sectional survey
Eriksson Landu · Joseph Nsiala · Arriel Makembi Bunkete · Wilfrid Mbombo · Stéphane Mutombo · Patrick Mukuna · Carl Lemba · Christian Nantulu · Patricia Kabuni · Alphonse Mosolo · Jean-Pierre Ilunga · Benjamin Kabwe · Médard Bulabula · Berthe Barhayiga
Frontiers in Pain Research
doi 10.3389/fpain.2026.1968968
Original Research
Published
The diagnostic accuracy of ultrasonography in pediatric intussusception and its role in predicting the need for surgery
Murat Solmaz · Osman Gultekin · Ozhan Orhan · Devran Demir
Frontiers in Pediatrics
doi 10.3389/fped.2026.1940450
Original Research
Published
Endovascular treatment versus best medical treatment for acute anterior cerebral artery occlusion: a single-center inverse probability of treatment-weighted cohort study
Xiaolin Wan · Baoming Lei · Kun Tang · Haifeng Liu · Yi Yang · Wenhua Liu · Zhangbao Guo
Frontiers in Neurology
doi 10.3389/fneur.2026.1896249
Methods
Published
NEOBIC-XR: a home-based extended reality exercise platform and multicenter evaluation framework for supportive oncology care
Alex Fuentes-Raventos · Mel Slater · Paula Jimenez-Fonseca · Patricia Cruz-Castellanos · Ane Ruiz-Eguino · Carmen Naveiras-Alba · Berta Obispo · Xim Cerda-Company · Jesús Menéndez-López · Caterina Calderon
Frontiers in Virtual Reality
doi 10.3389/frvir.2026.1927617
Original Research
Published
Prognostic value of postoperative dynamic PNI trajectories for biochemical recurrence in patients with high-risk localized prostate cancer: a longitudinal trajectory clustering study
Bo Yu · Xuchao Dai · Jianguo Zhu
Frontiers in Nutrition
doi 10.3389/fnut.2026.1963784
Original Research
Published
Persistent postoperative pediatric pain: a secondary analysis of the 4P prospective observational multicenter study
Anna K. M. Persson · Johanna Broman
Frontiers in Pain Research
doi 10.3389/fpain.2026.1930534