Original ResearchPublished 4 September 2026Comparative in vitro safety assessments of synthetized and plant-derived cannabidiol (CBD), and pharmacokinetics of synthetized CBD: evidence of similar toxicological profiles and accumulation upon repeated oral administrationE. T. Wong · D. Bovard · W. K. Schlage · W. Xia · H. Isa · O. Sirbu · A. R. Kolli · G. N. Nikolajsen · S. S. Jensen · J. Ho · B. Phillips · J. HoengFrontiers in Toxicologydoi 10.3389/ftox.2026.1844643