Hypothesis and TheoryPublished 24 August 2026Relative Sertoli-cell FSH hyporesponsiveness as a potential contributor to sperm DNA fragmentation: a hypothesis-driven narrative review and proposal of the FERTILE frameworkHussein KandilFrontiers in Urologydoi 10.3389/fruro.2026.1915445
Specialty Grand ChallengePublished 5 August 2026Grand challenges in anesthetic pharmacology: toward personalized, outcome-focused practiceTomohiko AoeFrontiers in Anesthesiologydoi 10.3389/fanes.2026.1934044
Original ResearchPublished 11 June 2026Computational analysis and validation of UGT1A1/4 missense variants impacting tecovirimat metabolism in monkeypox patientsAmro A. Abdelazim · Sameh E. Hassanein · Mohamad Maged · Nada S. Al-Theyab · Itoh Kimiko · Kotb A. AttiaFrontiers in Systems Biologydoi 10.3389/fsysb.2026.1821230
Epigenetics and EpigenomicsPublished 30 October 2025Epigenetic repurposing of carbohydrate metabolic inhibitors for insulin resistance: targeting DNMT1 and HDAC3 for β-cell restorationMuhammad Javid Iqbal · Luis A. SalazarFrontiers in Epigenetics and Epigenomicsdoi 10.3389/freae.2025.1691949