Review
Published
Flavonoids in cancer pharmacology: molecular mechanisms, tumor microenvironment regulation, and drug resistance
Zhengyuan Yu · Zhanyi Zhou · Ni Yin · Hongcheng Ge
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1969337
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 36 articles
Original Research
Published
Physiologically-based pharmacokinetic model to predict pharmacokinetics of KY0467 in humans and guide dose selection in infants and children
Panpan Xie · Yanyan Yang · Xuemei He · Ming Yang · Zhixing Chen · Xi Weng · Aixin Shi
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1866331
Original Research
Published
Independent correlates of vancomycin steady-state trough concentration among patients undergoing combined CABG and valve surgery: observational findings for intra-aortic balloon pump support
Bei-bei Shao · Tao Feng · Ji-cheng Jiang · Wen-lu Xing · Ming Ni · Lu-lu Li · Chao Liu · Shu-ping Meng · Yong-cheng Ma · Ai-feng Wang
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1888382
Mini Review
Published
From formation history to intra-articular service: coupling network evolution, fatigue, degradation, and drug release in adaptive hydrogel microspheres
Yang Gu · Fude Jiao · Yuqin Fang · Jun Zhang · Yong Hu · Yunqiang Zhuang
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1979560
Original Research
Published
Population cellular kinetics and exposure-CSR analysis of CAR-T cells in Chinese patients with relapsed/refractory B-ALL
Yicong Bian · Jinjie Yuan · Chenrong Huang · Kaijie Zhang · Ling Xue · Fan Xia · Liqing Kang · Yan Wang · Hua Zhang · Lei Yu · Depei Wu · Liyan Miao
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1878984
Case Report
Published
Case Report: Sustained pubertal suppression for 68 months with a single histrelin acetate implant in central precocious puberty
Sofya Ilmer · Parissa Salemi
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1951374
Case Report
Published
Case Report: Panic attacks after tirzepatide injection in two female patients with recurrent depressive disorder
Ulrich Palm · Markus Backmund · Hubertus Himmerich
Frontiers in Drug Safety and Regulation
doi 10.3389/fdsfr.2026.1880796
Clinical Trial
Published
An intravaginal ring for HIV pre-exposure prophylaxis: assessment of safety and pharmacokinetics in a randomized, placebo-controlled clinical trial
Kathleen L. Vincent · John A. Moss · Mark A. Marzinke · Richard B. Pyles · Lauren Dawson · Trevelyn J. Olive · Irina Butkyavichene · Amalia E. Castonguay · John M. Cortez · Mariana Remedios-Chan · Patricia Galvan · Sofia Rivera · Simon Webster · Manjula Gunawardana · Amy P. Adler · Christina M. Ramirez · Hans M. L. Spiegel · Craig W. Hendrix · Peter A. Anton · Marc M. Baum
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1955105
Original Research
Published
Instillation timing as the main determinant of aqueous humor nepafenac exposure
Angelo Macri · Annalisa Salis · Margherita Tarallo · Michele Iester · Gianluca Damonte · Francesca Mattioli
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1913752
Review
Published
Phytocannabinoid-drug interactions: pharmacokinetic and pharmacodynamic mechanisms, clinical relevance and toxicological considerations
Diogo Alexandre Gomes · Wellyngton Vieira Eufrázio · Marcella Silva Ribeiro · Linério Ribeiro de Novais Júnior · Flávia Rigo · Patrícia de Aguiar Amaral · Antonella Campanale · Antônio Inserra · Rafael Mariano de Bitencourt
Frontiers in Toxicology
doi 10.3389/ftox.2026.1952599
Review
Published
Black boxes and petri dishes: AI models for antimicrobial pharmacokinetics, drug properties, and resistance
Jacob K. McPherson · Surbhi Sharma · Biswajit Mishra · Fadi Shehadeh · Eleftherios Mylonakis
Frontiers in Bacteriology
doi 10.3389/fbrio.2026.1926678
Review
Published
Tanshinone IIA and sodium tanshinone IIA sulfonate in ischemic stroke: evidence, exposure, and translational readiness
Aiyue Fan · Weiting Chen · Min Tang · Yangtian Ye · Yaling Jin
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1959038
Review
Published
Ferroptosis nanomedicine for cancer therapy: strategies and challenges
Yanpin Ma · Ziyi Xu · Hudabia Akram · Tiancheng Yang · Jiachun Sun · Xinyu Gu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1950781
Review
Published
Next-generation nanomedicine for cancer therapy: advances, challenges, and future perspectives
Biswajit Mohanty · Puja Saikia · Piyush Pandey · Chira R. Bhattacharjee
Frontiers in Chemistry
doi 10.3389/fchem.2026.1920337
Mini Review
Published
Menopause-associated gut microbiome remodeling and pharmacomicrobiomics: emerging mechanisms influencing drug response
Susanne B. Haga
Frontiers in Microbiomes
doi 10.3389/frmbi.2026.1953547
Review
Published
Innovative nanomedicine strategies for precision-controlled targeted drug delivery: recent preclinical progress
Ashna Sureshkumar · Prakash Balu
Frontiers in Biomaterials Science
doi 10.3389/fbiom.2026.1916503
Review
Published
Gastrointestinal complications of cocaine use: a narrative literature review
Abeer Qasim · Saran Lal Ajai Mokan Dasan · Fnu Veena · Sameer Kandhi · Harish Patel
Frontiers in Gastroenterology
doi 10.3389/fgstr.2026.1907090
Original Research
Published
Comparative in vitro safety assessments of synthetized and plant-derived cannabidiol (CBD), and pharmacokinetics of synthetized CBD: evidence of similar toxicological profiles and accumulation upon repeated oral administration
E. T. Wong · D. Bovard · W. K. Schlage · W. Xia · H. Isa · O. Sirbu · A. R. Kolli · G. N. Nikolajsen · S. S. Jensen · J. Ho · B. Phillips · J. Hoeng
Frontiers in Toxicology
doi 10.3389/ftox.2026.1844643
Review
Published
Expanding treatment options for syphilis during pregnancy: a review of alternatives to penicillin
Claire L. Townsend · Lynne Mofenson · Sami Gottlieb · Remco P. H. Peters · Oriol Mitjà · Clara Pérez-Mañá · Elaine J. Abrams · Sinead Delany-Moretlwe · Shahin Lockman · Catriona Waitt · Kathryn Miele · Melanie M. Taylor · Françoise Renaud
Frontiers in Global Women's Health
doi 10.3389/fgwh.2026.1879243
Original Research
Published
Breastmilk transfer and infant exposure to atazanavir/ritonavir in breastfeeding women with HIV: results from IMPAACT 2026
Emily Anne Barr · Mauricio Pinilla · Jeremiah D. Momper · Ahizechukwu C. Eke · Lucy Koech · Kristina M. Brooks · Victoria Ndyanabangi · Sandra K. Burchett · Sujith Valiyaparambil · Mark Mirochnick · Alice Marie Stek · Brookie M. Best · Rachael Jeffrey · Chelsea Stotz · Marije Van Schalkwyk · Renee Browning · David E. Shapiro · Kathleen M. Powis
Frontiers in Reproductive Health
doi 10.3389/frph.2026.1892081
Review
Published
Beyond one drug–one target: AI-guided discovery of multi-target antiviral therapeutics
Vrinda Gupta · Sahil Sharma · Vikrant Abbot · Rohit Bhatia · Neeraj Choudhary · Dinesh Kumar
Frontiers in Virology
doi 10.3389/fviro.2026.1853552
Perspective
Published
Redefining the geography of pharmaceutical innovation: Kelly Chibale as a harbinger for integrated drug discovery in Africa
Fidele Ntie-Kang · Peter Mubanga Cheuka · Richard Kwamla Amewu · Elizabeth V. M. Kigondu · Collen Masimirembwa
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1884834
Correction
Published
Correction: Fundamentals of dermatologic drug discovery
Frontiers Editorial Office
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1939675
Mini Review
Published
Nanosystems for delivery of indolicidin peptide
José Gregorio Martín Bedoya · Katia Conceição
Frontiers in Medical Technology
doi 10.3389/fmedt.2026.1845120
Perspective
Published
Modulating the human gut microbiome-host system: a new drug discovery paradigm
Gonzalo Colmenarejo
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1898583
Review
Published
Fundamentals of dermatologic drug discovery
Ayman Grada
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1777138
Review
Published
Physical feasibility gating in early drug discovery: a decision framework for identifying predictable physical failures, with retrospective illustration
Sarfaraz K. Niazi
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1799663
Review
Published
Analytical similarity as the primary determinant of monoclonal antibody development: toward evidence-efficient regulatory frameworks
Sarfaraz K. Niazi
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1801236
Review
Published
Beyond GLP-1: underexplored peptide–receptor systems as the next frontier in drug discovery
Sarfaraz K. Niazi
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1792418
Mini Review
Published
Navigating the complexity of oral peptide delivery: challenges and strategies to enhance oral bioavailability
Noor-Ul-Ain Khalid · Edgardo Rivera-Delgado · Thomas von Erlach
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1809842
Original Research
Published
Search for marker proteins to assess blood–brain barrier development
Yukari Shigemoto-Mogami · Kimiko Nakayama-Kitamura · Kaoru Sato
Frontiers in Neuroanatomy
doi 10.3389/fnana.2026.1717532
Review
Published
Local delivery of tranexamic acid for hemorrhage control in trauma: a narrative review
Henry T. Peng · Christian J. Kastrup · Catherine Tenn · Andrew Beckett
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1771095
Mini Review
Published
Precision anesthesia and pharmacogenomics: a scoping review of personalized drug response
Sarina Nikzad · Ofelia Loani Elvir-Lazo · Robert Wong
Frontiers in Anesthesiology
doi 10.3389/fanes.2026.1727481
Drug Safety and Regulation
Published
Developing decision support algorithm for hypertension medications for use in a digital therapeutic system
Jeannie K. Lee · J. Skye Nicholas · Amani Albadawi · Kathleen C. Insel
Frontiers in Drug Safety and Regulation
doi 10.3389/fdsfr.2025.1476998
Analytical Science
Published
Enhancing constituent estimation in nucleic acid mixture models using spectral annealing inference and MS/MS information
Taichi Tomono · Satoshi Hara · Junko Iida · Takashi Washio
Frontiers in Analytical Science
doi 10.3389/frans.2025.1494615
Analytical Science
Published
A Bayesian approach for constituent estimation in nucleic acid mixture models
Taichi Tomono · Satoshi Hara · Yusuke Nakai · Kazuma Takahara · Junko Iida · Takashi Washio
Frontiers in Analytical Science
doi 10.3389/frans.2023.1301602