Review
Published
When absence becomes functional: lysine deserts in protein regulation and evolution
Natalia A. Szulc
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1959694
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Articles
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Showing 19 articles
Original Research
Published
Tumor-educated macrophages promote ferroptosis inhibition in pancreatic cancer via activating the p62-KEAP1-NRF2 pathway
Shouying Li · Dongxue Qi · Hanyang Yi · Lina Yang · Tonglei Xu · Wenkai Zhou · Weidong Xu · Ziheng Xu · Haodong Tang · Fangliang Xie · Chunfang Zhang · Xuyang Liang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938077
Review
Published
NEDD4-1: from molecular mechanisms to clinical translation in human diseases
Haifen Tian · Yongsheng Huang · Yun Liang · Chengjun Huang · Bingbing Wei · Chang-Neng Liao · Weijie Zhou
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1897001
Review
Published
Role of histone post-translational modifications in preeclampsia: from pathogenesis to diagnostic and therapeutic strategies
Yuanxuan Ma · Renwei Zhang · Mengting Yang · Jingli Wang · Bo Hou · Shiguo Liu
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1973542
Review
Published
The 19S proteasome as a therapeutic target in hematologic malignancies
Idaly M. Olivas · Mayra A. Gonzalez-Henry · Saeedeh Darvishi · Evelyn M. Esparza · Anna M. Eiring
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1918833
Mini Review
Published
TRIM22 in cancer: a context-dependent E3 ligase at the interface of interferon, p53, and tumor plasticity
Chenjie Qiu · Liangliang Dai
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1977247
Review
Published
Stress granule phase transitions and neuronal fate in cerebral ischemia-reperfusion injury
Xue Liao · Li Li · Xiaohong Zhang · Qin Chen · Chunyan Guo · Jinsong Luo · Tian Wang · Zuhong Wang
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1927505
Review
Published
Activation of silent synapses driven by emerging technologies: mechanisms, disease associations, and prospects for clinical translation
Yongli Li · Yong Liao · Shouyao Zhang · Chenggui Xu · Ruhua Lan · Pengbin Zhao · Ruilu Liu · Yongli Song · Xinghe Zhang
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2026.1923815
Original Research
Published
New mechanistic insight into SARM1 activation: TRIM32-mediated ubiquitination is a key lever that actuates SARM1’s catalytic action, leading to axon degeneration and cell death
Hitoshi Murata · Nahoko Tomonobu · Ken-ichi Yamamoto · Rie Kinoshita · Masakiyo Sakaguchi
Frontiers in Neural Circuits
doi 10.3389/fncir.2026.1842408
Original Research
Published
Gap junction protein connexin 36 proteostatic mechanisms in photoreceptor cells subjected to excitotoxic stress
Monika Katan · Klaudia Mróz · Joanna Lewin-Kowalik · Adrian Smędowski
Acta Biochimica Polonica
doi 10.3389/abp.2026.16091
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Original Research
Published
Hydrogen peroxide as a multifaceted regulator of the Atg4 protease and autophagy in the pathogenic fungus Alternaria alternata
Hsin-Yu Lu · Je-Jia Wu · Celine Yen Ling Choo · Pei-Ching Wu · Kuang-Ren Chung
Frontiers in Fungal Biology
doi 10.3389/ffunb.2026.1881957
Review
Published
Post-translational modifications as a regulatory code for tau function in health and disease
Abigail J. Nordbeck · Bhirisha Sharma · Charles A. Garcia · Jui-Heng Tseng
Frontiers in Dementia
doi 10.3389/frdem.2026.1834737
Review
Published
Revisiting the clastosome: a stress-induced nuclear proteolytic compartment of mammalian cells
Miguel Lafarga · María T. Berciano · Noemí Rueda · Sofía Cardona-Cortés · Olga Tapia
Frontiers in Neuroanatomy
doi 10.3389/fnana.2026.1839944
Brief Communication
Published
Enhanced oxidative stress resilience in C. elegans acox-1.1 mutants through CTL-3 and proteasomal regulation
Woori Bae · Mina Norman · Myon Hee Lee
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10796
Review
Published
Thirty years of reaper: lessons learned from programmed cell death in Drosophila
Hermann Steller
Frontiers in Cell Death
doi 10.3389/fceld.2026.1770008
Cell Death
Published
The good, the bad, and the modified: CYLD’s post-translational tale
Yanis M. Macé · Nicolas Bidère · Tiphaine Douanne
Frontiers in Cell Death
doi 10.3389/fceld.2025.1583221
Biophysics
Published
Functional dynamics of human ubiquitin C-terminal hydrolases
Sarita Puri · Shang-Te Danny Hsu
Frontiers in Biophysics
doi 10.3389/frbis.2024.1479898
RNA Research
Published
SUMOylation regulation of ribosome biogenesis: Emerging roles for USP36
Yunhan Yang · Yanping Li · Rosalie C. Sears · Xiao-Xin Sun · Mu-Shui Dai
Frontiers in RNA Research
doi 10.3389/frnar.2024.1389104
RNA Research
Published
The Cajal body marker protein coilin is SUMOylated and possesses SUMO E3 ligase-like activity
Katheryn E. Lett · Douglas M. McLaurin · Sara K. Tucker · Michael D. Hebert
Frontiers in RNA Research
doi 10.3389/frnar.2023.1197990