PerspectivePublished 4 September 2026The importance of the life cycle perspective for safety assessment in the European Commission’s Safe and Sustainable by Design FrameworkIrantzu Garmendia Aguirre · Irini Furxhi · Agnieszka Mech · Kirsten Rasmussen · Hubert RauscherFrontiers in Toxicologydoi 10.3389/ftox.2026.1909986