Articles

Showing 275 articles

• Original Research

  Published 12 August 2026

  Mepolizumab reduces systemic corticosteroid-related toxicities and healthcare burden in patients with eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome: a retrospective database study

  Thanai Pongdee · Jared Silver · Arijita Deb · Francois Laliberte · Chi Gao · Annalise Hilts · Kaixin Zhang · Daisy Liu · Amy G. Edgecomb

  Frontiers in Allergy

  doi 10.3389/falgy.2026.1843149

• Case Report

  Published 11 August 2026

  Case Report: Pancreatic amphicrine-like carcinoma with acinar differentiation harboring a KANK4-RAF1 gene fusion

  Sabrina Kammerer · Peter Bode · Heide Schreiber · Guacimara Ortega Sanchez

  Pathology and Oncology Research

  doi 10.3389/pore.2026.1612537

• Brief Research Report

  Published 4 August 2026

  Computational design of orthogonal operators and synthetic repressors for transcriptional logic gates

  Nathaniel Howitz · Stephen N. Rondthaler · Lauren B. Andrews

  Frontiers in Synthetic Biology

  doi 10.3389/fsybi.2026.1854859

• Original Research

  Published 4 August 2026

  Heavy metal and pesticide toxicity in agricultural soils across a farming intensity gradient in Central Zambia

  Aaron C. Siyunda · Davies Lungu · Natasha M. Mwila · Jones Yengwe · Akbar A. Ganatra · Hemant Tripathi · Steven M. Sait · Rupert J. Quinnell · Martin Simuunza · Lavel Moonga · Xiaomei Yang · Rima Osman · Luuk Fleskens · Violet Nkhoma · Andy Dougill · Erastus Mwanaumo

  Frontiers in Soil Science

  doi 10.3389/fsoil.2026.1903905

• Review

  Published 30 July 2026

  Beyond one drug–one target: AI-guided discovery of multi-target antiviral therapeutics

  Vrinda Gupta · Sahil Sharma · Vikrant Abbot · Rohit Bhatia · Neeraj Choudhary · Dinesh Kumar

  Frontiers in Virology

  doi 10.3389/fviro.2026.1853552

• Original Research

  Published 29 July 2026

  In vitro cytotoxic and anti-inflammatory activities of Ayapana triplinervis essential oil and hydroethanolic extract

  Lucas Gabriel V. Barbosa · Luana de Sousa P. Barros · Alexandre Motta da Silva · Leandra Feliz Santos · Renata Cunha Silva · Carlos Vinícius A. da Silva · Raphael Oliveira de Figueiredo · Flavia Cristina A. Lucas · Laine Celestino Pinto · Joyce Kelly da Silva · Hector Henrique F. Koolen · Pablo Luis B. Figueiredo

  Frontiers in Natural Products

  doi 10.3389/fntpr.2026.1888636

• Review

  Published 29 July 2026

  Bioactive constituents of Hericium erinaceus: extraction strategies, health benefits and food applications

  Vibhuti Gurung · Narashans Alok Sagar · Nitu Rani

  Frontiers in Natural Products

  doi 10.3389/fntpr.2026.1872464

• Original Research

  Published 29 July 2026

  Synthesis, optimization, and biosafety assessment of nanozeolite-based slow-release nitrogen fertilizers for spinach beet (Beta vulgaris var. bengalensis)

  Pooja Lakshmidevarahalli Ramalingappa · Renu Singh · Shiva Dhar · Harshwardhan Choudhary · Jorge Gardea-Torresdey · Manoj Shrivastava

  Frontiers in Soil Science

  doi 10.3389/fsoil.2026.1820226

• Original Research

  Published 28 July 2026

  Burden of snakebite and the knowledge of health professionals toward envenomation management in Hamer wereda, South Omo, Ethiopia

  Jemal Mohammed · Demise Mulugeta · Anberebir Alemu · Abebe M. Aga · Fanos Tadesse Woldemariyam · Yeweynshet Tesera · Abate Waldetensai · Henok Ferede · Dejene Getachew · Ayele Bizuneh · Dereje Nigussie

  Frontiers in Tropical Diseases

  doi 10.3389/fitd.2026.1857331

• Original Research

  Published 27 July 2026

  Bioactivity screening of plant ethanol extracts against Plutella xylostella and field evaluation of an optimized botanical combination formulation

  Jie Zhang · Xiaoe Wang · Xiaoli Xu. · Williamson Gustave · Xiaokai Zhang

  Acta Biochimica Polonica

  doi 10.3389/abp.2026.16918

  2,321 views

• Original Research

  Published 24 July 2026

  Iron-oxide nanoparticle-integrated soft contact lenses: optical optimization, catalytic functionality, and biocompatibility

  Aswathi Ram P · Muhammed Shebeeb · Muhammed Hisham · Sanjana Chandran · Said El Turk · Haider Butt

  Frontiers in Medical Technology

  doi 10.3389/fmedt.2026.1782878

• Original Research

  Published 21 July 2026

  Closing the loop in aquaponics: biological and physicochemical recovery of nutrients from aquaculture sludge for circular bioeconomy

  Luca Gerdes genannt Janßen · Mostafa Elshobary · Noémie Ramos · Tamara Schwenkler · Stephan Ende · Anja Noke

  Frontiers in Aquaculture

  doi 10.3389/faquc.2026.1842840

• Mini Review

  Published 20 July 2026

  Nanosystems for delivery of indolicidin peptide

  José Gregorio Martín Bedoya · Katia Conceição

  Frontiers in Medical Technology

  doi 10.3389/fmedt.2026.1845120

• Review

  Published 16 July 2026

  The molecular pathways of polyphenols in combating multidrug-resistant microbial superbugs: a comprehensive mechanistic review

  Michael T. Bayode · Shina Oguntuase · Joseph Chimezie · Ayomide Okiti · Esther Oyedeji · Isaac Ajayi · Jeremiah Adesanya

  Frontiers in Natural Products

  doi 10.3389/fntpr.2026.1879559

• Original Research

  Published 16 July 2026

  Formulation and evaluation of quinoa seed oil loaded folic acid conjugated bovine serum albumin nanoparticles for anti-breast cancer activity

  Syed Abuzar Raza Rizvi · Rupali Ghosh · Zaid Siddiqui · Nancy Sanjay Gupta · Abul Vafa · Javed Ahmad · Saima Wajid

  Frontiers in Nanotechnology

  doi 10.3389/fnano.2026.1852250

• Review

  Published 15 July 2026

  PSMA-targeted radioligand therapy in advanced prostate cancer: a narrative review of ^177Lu-PSMA, emerging ^225Ac-PSMA strategies, and therapeutic sequencing

  Natalia Gierulska · Nina Jankowska · Adrianna Kwiatkowska · Piotr Kuchno · Kinga Łysak · Katarzyna Szklener · Kamil Kośmider · Magdalena Skórzewska

  Oncology Reviews

  doi 10.3389/or.2026.1834484

• Systematic Review

  Published 15 July 2026

  Global research landscape and trends of metabolomics in diabetic kidney disease: focus on immunometabolic interactions

  Yuting Li · Changlin Li · Jiamin Duan · Qingli Yang · Jing Zhang · Duo Yu · Yuwei Chen · Jianing Ni · Xiaomeng Lin · Xudong Cai

  Frontiers in Clinical Diabetes and Healthcare

  doi 10.3389/fcdhc.2026.1791774

• Original Research

  Published 8 July 2026

  Chemical profiling and pharmacological potential of myxobacteria isolated from Brazilian mangrove sediments

  Renan S. Oliveira · Luís G. F. Feitosa · Caio S. Moura · Elthon G. Ferreira · Andrezza J. Gozzo · Letícia V. Costa-Lotufo · Norberto P. Lopes · Anna C. C. Aguiar · Marcelo J. P. Ferreira · Paula C. Jimenez

  Frontiers in Natural Products

  doi 10.3389/fntpr.2026.1816108

• Original Research

  Published 7 July 2026

  Mapping the otoactive landscape: an LLM-aided extraction of compounds and their targets

  Aylin del Moral-Morales · Jean Arguello‐Camarillo · Jesús Yael Castañón Bello · Angélica Chavez-Romero · José L. Medina-Franco · Hugo Nájera · Gerardo Pérez-Hernández

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1834905

• Review

  Published 7 July 2026

  Obesity from the perspective of the liver

  Miklós Csala · József Mandl

  Pathology and Oncology Research

  doi 10.3389/pore.2026.1612376

• Editorial

  Published 7 July 2026

  Editorial: Engineered nanomaterials: understanding their toxicity and environmental impacts

  Sarmistha Saha · Brigitta Buttari · Luciano Saso

  Frontiers in Nanotechnology

  doi 10.3389/fnano.2026.1899853

• Original Research

  Published 6 July 2026

  Selective adsorption of Pb 2+ from acid mine drainage through a poly (hydroxamic acid) (PHA) ligand: an HSAB-guided coordination mechanism

  Nozipho Nompumelelo Mzinyane

  Frontiers in Environmental Chemistry

  doi 10.3389/fenvc.2026.1835320

• Review

  Published 2 July 2026

  CAR-T cell therapy in glioblastoma: from αβ to γδ T-cell platforms

  Costanza Dieli · Roberta Costanzo · Anna Maria Corsale · Federica Paolini · Marta Di Simone · Claudia Avellone · Francesco Dieli · Domenico Gerardo Iacopino · Salvatore Marchiafava · Rosario Maugeri · Serena Meraviglia

  Oncology Reviews

  doi 10.3389/or.2026.1808229

• Review

  Published 2 July 2026

  Positioning rituximab in the therapeutic strategies for SLE

  Chrysanthi Staveri · Stamatis-Nick C. Liossis

  Frontiers in Lupus

  doi 10.3389/flupu.2026.1877692

• Review

  Published 24 June 2026

  To label or not to label? The paradox of small-molecule probes in biological characterization

  Mario E. Cuevas-Galindo · Arturo Jiménez-Sánchez

  Frontiers in Photonics

  doi 10.3389/fphot.2026.1858154

• Review

  Published 23 June 2026

  Impact of plant-based interventions on gynecological cancers: a narrative review of mechanistic interplays and clinical evidence

  Fidelis Batale Fabrael · John Sotunsa · Kehinde Samuel Olaniyi · Onome Bright Oghenetega · Oluwatobi Adewale · Blessing Monica Akindele · Faith Olanrewaju · Nekabari Lekpa Gbimadee · Seyi Olayemi · Abosede Oreoluwa Bolaji · Marvellous Osewe Iyobhebhe · Emmanuel Mololuwa Adegbotoluwa · Emmanuel Damilare Folahanmi · John Ahmadu Kaisar · Precious Adeoye Oyedokun

  Frontiers in Molecular Medicine

  doi 10.3389/fmmed.2026.1832188

• Original Research

  Published 18 June 2026

  Identification of novel DNA gyrase B inhibitors in Mycobacterium species using integrated computational approaches

  Jagritee Yadav · Lalhmangaihzuali · Harish Shukla · Anshuman Chandra · Sudhir Kumar Singh · Meenakshi Singh

  Frontiers in Tuberculosis

  doi 10.3389/ftubr.2026.1854329

• Perspective

  Published 18 June 2026

  Glyphosate: North America's toxic food crops and the enduring legacy of disease

  J. A. Barnett · D. L. Gibson

  Frontiers in Environmental Health

  doi 10.3389/fenvh.2026.1863758

• Review

  Published 12 June 2026

  Cardio-oncology in multidisciplinary synergy: addressing the rising burden of cancer therapy-related cardiovascular toxicity (CTR-CVT) in advancing oncology practices

  Putri Dwi Astuti · Eko Adhi Pangarsa · Andreas Arie Setiawan · Daniel Rizky · Budi Setiawan · Charles Limantoro · Damai Santosa · Catharina Suharti

  Oncology Reviews

  doi 10.3389/or.2026.1852886

• Brief Research Report

  Published 12 June 2026

  Anti-leishmanial activity and dereplication using GC-MS assisted by molecular networking of the essential oil from the leaves and inflorescence of Melaleuca viminalis (myrtaceae)

  Ana Clara L. N. Silva · Marisi G. Soares · Eduard Choi Jr. · Gabriela V. Araujo Flores · Luiz Felipe D. Passero · Márcia D. Laurenti · Patrícia Sartorelli

  Frontiers in Natural Products

  doi 10.3389/fntpr.2026.1826685

• Original Research

  Published 12 June 2026

  Electrophysiological mechanisms behind the differential cardiotoxicity of chemotherapeutic agents Bortezomib and Carfilzomib

  Dario Melgari · Serena Calamaio · Anthony Frosio · Rachele Prevostini · Alessio Malacrida · Luigi Anastasia · Carlo Pappone · Gabriella Nicolini · Guido Cavaletti · Ilaria Rivolta

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1774061

• Original Research

  Published 12 June 2026

  Phenotypic profiling of Pathogen Box compounds MMV667494 and MMV028694 in bloodstream-form Trypanosoma brucei brucei

  Pearl Ihuoma Akazue · Neils Ben Quashie · Sue Vaughan · Harry P. de Koning · Theresa Manful Gwira

  Experimental Biology and Medicine

  doi 10.3389/ebm.2026.10979

• Original Research

  Published 11 June 2026

  An exploration of markers of microvascular dysfunction in kidney transplant recipients randomized to belatacept: no clinical impact of CNIs on endothelial function

  Edwin O. W. Bredewold · Rudmer J. Postma · Joe Chan · My H. S. Svensson · Annette Bruchfeld · Johannes W. de Fijter · Hans Furuland · Anders Hartmann · Lars Mjornstedt · Karin Skov · Inga soveri · Soeren S. Sorensen · Bengt Fellstrom · Jacques M. Duijs · Roel Bijkerk · Joris I. Rotmans · Anton-Jan van Zonneveld

  Frontiers in Transplantation

  doi 10.3389/frtra.2026.1812847

• Review

  Published 11 June 2026

  The cutaneous mirror: leveraging drug-induced skin phenotypes as early visual risk signals for systemic toxicity, a comprehensive review

  Hind B. Alshalhoob · Lama M. Albelowi · Aseel S. Alotaibi · Shada Khalid Alanazi · Leen E. Alturki · Zahra Saleh Alsindi · Waad Abdulelah Alduraywish · Sarah Anwar Almulla · Ahmed Anwar Almulla · Nouf Abdulaziz Almagushi · Sarah Khalifah Alkhezzi

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2026.1825005

• Original Research

  Published 11 June 2026

  Pelargonium graveolens essential oil against clinical Candida and reference isolates: insights into virulence inhibition and therapeutic perspectives

  Chahrazed Benzaid · Manel Lina Djendi · Sarra Touaibia · Lina Raghed Klaiaia · Ahlam Kihal · Lazhari Tichati · Amel Soussa · Mahmoud Rouabhia

  Frontiers in Fungal Biology

  doi 10.3389/ffunb.2026.1868001

• Perspective

  Published 9 June 2026

  Emerging role of genipin as a therapeutic in diseases of the peripheral nervous system

  Archie Patel · Nadja Zeltner

  Frontiers in Biomaterials Science

  doi 10.3389/fbiom.2026.1852025

• Review

  Published 8 June 2026

  Quantum dots for biomedical innovation: overview, applications, and biosafety

  JuCai Wang · YueHeng Qi · MeiQiu Xu

  Frontiers in Nanotechnology

  doi 10.3389/fnano.2026.1833993

• Systematic Review

  Published 5 June 2026

  Efficacy and safety of PD-1 inhibitors in recurrent or metastatic squamous cell carcinoma of the head and neck: a systematic review and meta-analysis

  Abdullah Alabbasi · Muhanad Alzahrani · Ziyad Alzahrani · Faris Sultan · Maha AlQahtani · Alaa Sultan

  Oncology Reviews

  doi 10.3389/or.2026.1745071

• Review

  Published 4 June 2026

  Vector-amplified toxicity of microplastics and heavy metals in aquatic invertebrates: mechanistic insights and implications for sustainable aquaculture

  Jaynos R. Cortes · John Lloyd F. Penionez · Jay D. Tering · Fabio C. Ruaza

  Frontiers in Aquaculture

  doi 10.3389/faquc.2026.1841755

• Original Research

  Published 3 June 2026

  Antiparasitic triterpenic ester and ursolic acid lipid nanocapsule design, cytotoxicity, and permeability evaluation for oral delivery

  Laura Schioppa · Cecilia Bohns Michalowski · Lucia Mamede · Romano Terrasi · Marie-France Hérent · Giulio G. Muccioli · Raphaël Frédérick · Michel Frederich · Ana Beloqui · Joelle Quetin-Leclercq

  Frontiers in Drug Delivery

  doi 10.3389/fddev.2026.1846904

• Systematic Review

  Published 28 May 2026

  Environmental epigenetic modifiers in neurodegenerative diseases: a systematic review of epigenomic mechanisms and therapeutic targets

  Pranay Wal · Sunita Mishra · Debashish Pradhan · Ankita Wal · Debashis Purohit · Lalit Mohan Nainwal · Vivek Dhir · Amin Gasmi

  Frontiers in Epigenetics and Epigenomics

  doi 10.3389/freae.2026.1833533

• Original Research

  Published 22 May 2026

  Scaling human liver microphysiological systems: implementing a higher-throughput liver acinus microphysiological system platform

  Dillon C. Gavlock · Michael W. Castiglione · Allen Wang · Mahboubeh Varmazyad · Lawrence A. Vernetti · Mark E. Schurdak · D. Lansing Taylor · Jacquelyn A. Brown · Mark T. Miedel

  Experimental Biology and Medicine

  doi 10.3389/ebm.2026.11038

• Original Research

  Published 21 May 2026

  A pilot study on therapeutic drug monitoring of asparaginase in Indian children with high-risk ALL: evidence for suboptimal exposure

  Himanshu Dhanda · Shamsuz Zaman · Bhavika Rishi · Raj Kamal · Manpreet Kaur · Nitika Anand · Baseer Noor · Pranay Tanwar · Sufian Zaheer · Prashant Prabhakar · Fouzia Siraj · Amitabh Singh · Aroonima Misra

  Frontiers in Hematology

  doi 10.3389/frhem.2026.1779396

• Perspective

  Published 20 May 2026

  Convergent mitochondrial toxicity of fluorinated agents in oncological anaesthesia: sevoflurane, 5-fluorouracil, and the ACOD1/itaconate immune axis

  Ivan N. Dushin

  Frontiers in Anesthesiology

  doi 10.3389/fanes.2026.1839640

• Review

  Published 18 May 2026

  Pathogenesis of diabetic cardiomyopathy and emerging therapeutic strategies: a network-based perspective

  Haoqing Ren · Hengli Lai

  Frontiers in Clinical Diabetes and Healthcare

  doi 10.3389/fcdhc.2026.1823872

• Original Research

  Published 15 May 2026

  Virtual screening and molecular dynamics simulations of cannabinoid receptor 2 agonists as drug candidates for osteoarthritis therapy

  Fernanda F. De Souza · Juliana F. Vilachã · Heberth De Paula · Kathia Maria Honorio

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1809420

• Original Research

  Published 13 May 2026

  Programmable Ru(II) phototherapeutics: master dials, mode switches, and coligand-controlled reactivity

  Alisher Talgatov · Gurleen Kaur · Ge Shi · John A. Roque · Patrick C. Barrett · Debby Sunday · Tariq Sainuddin · Susy Kim · Gagan Deep · Antonio Francés-Monerris · Marta E. Alberto · Colin G. Cameron · Sherri A. McFarland

  Frontiers in Chemical Biology

  doi 10.3389/fchbi.2026.1771939

• Review

  Published 11 May 2026

  The mucosal-neural axis in chemotherapy-induced gastrointestinal toxicity

  Mikaela R. Nemani · Sandra Rieger

  Oncology Reviews

  doi 10.3389/or.2026.1814601