Articles

Showing 339 articles

• Original Research

  Published 12 October 2026

  Camk2d upregulation is associated with postoperative cognitive dysfunction in aged rats: pharmacological inhibition of CaMKII attenuates hippocampal neuroinflammation and neuronal apoptosis

  Kaihua Wei · Shiwen Fan · Yujia Zhao · Xiaobin Cai · Xinlei Qin · Jingwen Zhai · Liping Xie

  Frontiers in Aging Neuroscience

  doi 10.3389/fnagi.2026.1975677

• Mini Review

  Published 12 October 2026

  The impact of aging, sex, and exercise on brain mitochondria

  Jianhua Zhang · Victor Darley-Usmar · Yun Li

  Frontiers in Aging

  doi 10.3389/fragi.2026.1920914

• Systematic Review

  Published 12 October 2026

  Interventions for mental health and substance use in brain injury populations: systematic evidence map and review with interactive data visualization

  Cole J. Kennedy · Yichun Zhao · Simon Kurkimaki · Nicholas Gavas · Emily L. Spargo · Bernard Dupriez-Mitchell · Devon Rees · Zahra Premji · Erica Woodin · Julia Schmidt · Janelle Breese Biagioni · Mauricio A. Garcia-Barrera

  Frontiers in Digital Health

  doi 10.3389/fdgth.2026.1748621

• Review

  Published 12 October 2026

  The liver–gut–bone axis in hepatic osteodystrophy: mechanisms, clinical evidence and therapeutic perspectives

  Liangping Zhang · Ting Jiang · Rongqi Cao · Linqiu Han · Ligang Ni

  Frontiers in Cellular and Infection Microbiology

  doi 10.3389/fcimb.2026.1935323

• Review

  Published 12 October 2026

  Mitochondrial quality control at the ferroptosis-pyroptosis interface in diabetic cardiomyopathy: a narrative critical synthesis

  Shibo Sun · Jiarui Li · Mingxiu Sun · Xin Song · Ming Tang · Likun Du

  Frontiers in Cardiovascular Medicine

  doi 10.3389/fcvm.2026.1950950

• Case Report

  Published 12 October 2026

  Case Report: staged segment-specific open and endovascular treatment of chronic post-dissection aortic disease with descending thoracic and giant infrarenal aneurysmal components

  Azat Chinaliyev · Mukhammejan Orazbay · Gulinur Chinaliyeva · Didar Khassenov · Tokan Sultanaliyev · Irlan Sagandykov · Aktolkyn Daumen

  Frontiers in Cardiovascular Medicine

  doi 10.3389/fcvm.2026.1925462

• Original Research

  Published 12 October 2026

  Barriers and facilitators for sustainable fall prevention in a Chinese tertiary hospital: perspectives from nurses and managers

  Xiang Chen · Mi Zhao · Zhenhui Tao · Bei Li · Dan Zhu · Jingwen Meng · Mengyun Yang · Ziye Huang · Chenchen Zhao · Chunyue Li · Qiaohong Wang

  Frontiers in Public Health

  doi 10.3389/fpubh.2026.1939324

• Review

  Published 12 October 2026

  Multi-omics insights into immune dysregulation and candidate biological programs in kawasaki disease: toward precision immunomodulation

  Yun Han · Jiaying Liu · Chengxu Song · Li Fu · Yu Gu · Yu Zeng · Zhenzhuang Zou

  Frontiers in Pediatrics

  doi 10.3389/fped.2026.1960681

• Review

  Published 12 October 2026

  Non-acid reflux and reflux laryngitis: new perspectives on mechanism, diagnosis and treatment

  Hongshan Chang · Rui Sun · Huan Qiu · Yunhong Ning · Lei Yao

  Frontiers in Medicine

  doi 10.3389/fmed.2026.1949945

• Mini Review

  Published 12 October 2026

  Arsenic trioxide-induced cardiotoxicity: insights into the oxidative stress-inflammation positive feedback loop, translational biomarkers and targeted cardioprotective strategies— a narrative review

  Haiyan Wu · Jian Lv · Xiaoyang Hu

  Frontiers in Oncology

  doi 10.3389/fonc.2026.1954263

• Review

  Published 12 October 2026

  Antitumor immunity and immune-related toxicity during immune checkpoint inhibition: mechanistic overlap, tissue selectivity, and interventional evidence

  Chengyan Shi · Chunhai Li · Jun Yan

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1958441

• Review

  Published 12 October 2026

  Autophagy in Pseudomonas aeruginosa infection: host defense, bacterial countermeasures, and therapeutic targeting

  Bingbing Zhang · Yanling Huang · Lingling Wen · Qiaoli Hua · Lijun Zhao · Jiangang Shen · Meiling Zhu

  Frontiers in Microbiology

  doi 10.3389/fmicb.2026.1976209

• Review

  Published 12 October 2026

  TA-TMA as a clinical model for precision complement therapeutics in stem cell transplantation

  Sonata Jodele

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1959683

• Review

  Published 12 October 2026

  Glutamine metabolic reprogramming in acute and chronic kidney diseases: mechanistic insights and therapeutic implications

  Ruotong Xu · Jin Zhao · Minna Liu · Yifan Qiao · Xiaoxuan Ning · Shiren Sun

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1939528

• Review

  Published 12 October 2026

  Epigenetic and mitochondrial regulation in kidney disease: emerging mechanisms and therapeutic opportunities

  Atul Rawat · Narayan Prasad · Chandan Komalkumar · Harshit Singh · Saurabh Chaturvedi · Sultan Ahmed · Brijendra Kumar · Ravi Shankar Kushwaha

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1910925

• Review

  Published 12 October 2026

  Lactate dynamics at the Pseudomonas aeruginosa –host interface: bacterial metabolism, host defense, and emerging links to histone lactylation

  Yi Jian · Zhijie Wu · Yuqiang Liang · Jin Cao · Mei Li · Fashuang Yang · Ke Wang

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1979311

• Original Research

  Published 12 October 2026

  Low-frequency passive mechanical stimulation produces antidepressant-like effects in rats involving gut–brain axis modulation

  Rong Gao · Wenjing Pu · Yifei Lv · Liqiong Liu · Yan Zhao · Hao Liu · Li Chen · Nan Guan · Hongen Li

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1928978

• Original Research

  Published 12 October 2026

  Admission-based predictors of in-hospital AKI in HFrEF: a single-centre retrospective study

  Feng Dai · Xiaomin Li · Zihe Wang · Siyu Tan · Fengyang Han · Xiang Song

  Frontiers in Physiology

  doi 10.3389/fphys.2026.1928628

• Original Research

  Published 12 October 2026

  Berberine ameliorates thioacetamide-induced liver injury in zebrafish through PPARγ signaling and restores bile acid homeostasis

  Peng Sun · Jun Wu · Xiaoyu Zhu · Yanshuang Ren · Zhanyi Zhou · Wenjian Zhen · Yuan Ma · Xue Ding · Menghan Huang · Yuying Zhang · Wei Gong · Hao Wang

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1881966

• Review

  Published 12 October 2026

  High-altitude gastric disorders: insights into maladaptation pathophysiological mechanisms, disease spectrum and prevention strategies

  Huihui Shang · Rong Zhang · Youbang Xie · Airong Yang · Jing Wang

  Frontiers in Physiology

  doi 10.3389/fphys.2026.1944395

• Original Research

  Published 12 October 2026

  Taxifolin alleviates podocyte injury and macrophage chemotaxis associated with diabetic nephropathy by directly targeting RBP1 identified via multi-omics and machine learning

  Zi-Xuan Wang · Wen-Xuan Wang · Qiong-Dan Liang · Ling-Dong Kong

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1933167

• Original Research

  Published 12 October 2026

  Electroacupuncture pretreatment attenuates myocardial ischemia/reperfusion injury-induced ferroptosis via the p53/SLC7A11/GPX4 pathway

  Jing Mao · Qian-Ru Guo · Yi-Pu Luo · Cong-Fei Liu · Zhen-Yang Cao · Yun-Tao Yu · Wen-Wei Wu · Xin-Yu Luan · Dan-Ning Xu · Hua Wang · Pu Chen · Song Wu

  Frontiers in Physiology

  doi 10.3389/fphys.2026.1928208

• Original Research

  Published 12 October 2026

  Quercetin attenuates polystyrene nanoplastic-induced intestinal barrier injury through modulation of macrophage inflammatory responses

  Jian Kang · Heng Yang · Yan Wang · Xin Zhang · Chunyang Zhu · Yanhong Zhou · Yanqin Li

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1973458

• Original Research

  Published 12 October 2026

  Whole-exome sequencing reveals cumulative rare variant burden associated with susceptibility to anti-tuberculosis drug-induced liver injury in a Han Chinese cohort

  Yang Hao · Xiaoqing Zhang · Daiyun Huang · Shengyin Qin · Yunxiao Lin · Jianwen Ruan · Lu Shen · Na Zhang · Zhenting Wang · Cong Huai · Jianquan Zhang

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1952049

• Mini Review

  Published 12 October 2026

  From emergency myelopoiesis to trained immunity? Reframing post-stroke myeloid reprogramming along the brain-bone marrow axis

  TongZhu Wei · YongJiu Wang

  Frontiers in Neurology

  doi 10.3389/fneur.2026.1976078

• Editorial

  Published 12 October 2026

  Editorial: Photobiomodulation therapy for brain disorders, volume II

  Qianting Deng · Ge Song · Luodan Yang

  Frontiers in Neurology

  doi 10.3389/fneur.2026.2009205

• Original Research

  Published 12 October 2026

  Development and internal validation of a clinical prediction model for postoperative venous thromboembolism after neurosurgical intervention in patients with traumatic brain injury

  Dongping Li · Jianhui Chen · Chunfa Weng · Jianhuang Huang

  Frontiers in Neurology

  doi 10.3389/fneur.2026.1953953

• Mini Review

  Published 12 October 2026

  Mapping the neural basis of the perception of “flow of time”: interval timing and mental time travel in the human brain

  Ryuta Ochi · Mitsuru Kawamura

  Frontiers in Neurology

  doi 10.3389/fneur.2026.1960572

• Case Report

  Published 12 October 2026

  Case Report: Laser thermal ablation for severe primary hyperparathyroidism in a pregnant patient with MEN1 syndrome

  Mateusz Obal · Marcin Motyka · Grzegorz Sokołowski · Tomasz Piskorz · Hubert Huras · Alicja Hubalewska-Dydejczyk

  Frontiers in Endocrinology

  doi 10.3389/fendo.2026.1964081

• Retraction

  Published 12 October 2026

  Retraction: 17β-Estradiol protects neural stem/progenitor cells against ketamine-induced injury through estrogen receptor β pathway

  Frontiers Editorial Office

  Frontiers in Neuroscience

  doi 10.3389/fnins.2026.2017403

• Hypothesis and Theory

  Published 12 October 2026

  Synchrony in neural and visceral systems: a bioelectric basis of consciousness

  Ravinder Jerath · Varsha Malani

  Frontiers in Neuroscience

  doi 10.3389/fnins.2026.1642963

• Review

  Published 9 October 2026

  Natural compounds as potential countermeasures for spaceflight-associated neuro-ocular syndrome

  R. Mikal Lange · Tasneem P. Sharma

  Frontiers in Ophthalmology

  doi 10.3389/fopht.2026.1801651

• Correction

  Published 9 October 2026

  Correction: Perioperative management for invasive brain–computer interface implantation under surgical navigation in a patient with traumatic spinal cord injury: a case report

  Shuhui Yang · Qiang Sun · Hong Mo · Wenyao Cui

  Frontiers in Human Neuroscience

  doi 10.3389/fnhum.2026.1995038

• Review

  Published 9 October 2026

  Gene, microbiome, and anti-aging doping in sport: molecular mechanisms, detection strategies, and implications for sports rehabilitation medicine

  Diego Cotella

  Frontiers in Sports and Active Living

  doi 10.3389/fspor.2026.1984895

• Original Research

  Published 9 October 2026

  Evaluation of large language models for ICI-related liver injury with an emerging microbiome focus

  Man Sun · Dan Zang · Huan Zhou · Jun Chen

  Frontiers in Cellular and Infection Microbiology

  doi 10.3389/fcimb.2026.1955356

• Original Research

  Published 9 October 2026

  Risk factors for aortic disease combined with coronary artery disease and the significance of preoperative coronary assessment in endovascular aortic repair

  Yuping Lei · Mingduo Zhang · Mengmeng Wang · Xuewen Qi · Yuzeng Xue · Yong Yang · Hang Gao · Zhongzhi Liu · Zebo Xiu

  Frontiers in Cardiovascular Medicine

  doi 10.3389/fcvm.2026.1967015

• Mini Review

  Published 9 October 2026

  Risk stratification of pediatric chest pain: red flags, diagnostic yield, and an evidence-informed clinical framework

  Lingling Meng · Wenjing Zhu · Jianli Lv

  Frontiers in Pediatrics

  doi 10.3389/fped.2026.1988473

• Systematic Review

  Published 9 October 2026

  Extracorporeal kidney support in neonates and infants: therapeutic perspectives and outcomes in multiple organ dysfunction syndrome—a structured narrative review

  Gulmira Zhauarova · Dinagul Baesheva · Gulnur Nadirbekova · Kamilla Rakhimova · Bolat Bekishev · Talgat Ibrayev

  Frontiers in Pediatrics

  doi 10.3389/fped.2026.1739965

• Review

  Published 9 October 2026

  Thermal micro-insults during routine dental procedures: a forgotten determinant of pulp and dentine fate - a scoping review

  Chinmay D. Bhat · Vandana Sadananda · Gowrish S. Bhat

  Frontiers in Dental Medicine

  doi 10.3389/fdmed.2026.1917342

• Original Research

  Published 9 October 2026

  Association of Serum GDF-15 with Bone and Muscle Parameters in Community-Dwelling Individuals

  Nicia I. Profili · Sokratis Makrogiannis · Roberto Castelli · Maria Benelli · Valeria Orrù · Michele Marongiu · Edoardo Fiorillo · Francesco Cucca · Alessandro P. Delitala

  Frontiers in Medicine

  doi 10.3389/fmed.2026.1920342

• Original Research

  Published 9 October 2026

  Explainable machine learning for preoperative prediction of acute kidney injury after intertrochanteric fracture surgery in older adults

  Weizhang Lin · Ximing Lin · Hongpeng Gao

  Frontiers in Medicine

  doi 10.3389/fmed.2026.1961926

• Original Research

  Published 9 October 2026

  Identification and validation of early vital sign trajectory subphenotypes for risk stratification in sepsis-associated liver injury: a multicenter retrospective cohort study

  Weihang Wang · Jing Ma · Bingqing Wang · Jiayang Wang · Zexi Zang · Qiyao Liu · Zhi Gao · Wei Chen · Yuxin Deng · Zhiqing Zhang · Yongfang Jiang

  Frontiers in Medicine

  doi 10.3389/fmed.2026.1835574

• Original Research

  Published 9 October 2026

  Age-related hepatic tolerance to ischemia-reperfusion injury in a rat model of extended hepatectomy

  Dmitry G. Akhaladze · Ivan V. Tverdov · Alexander A. Andreev-Andrievskiy · Mikhail A. Mashkin · Olga Yu. Frolova · Nikolay S. Grachev

  Frontiers in Surgery

  doi 10.3389/fsurg.2026.1902759

• Review

  Published 9 October 2026

  Genesis—progression of early jaw osteoradionecrosis in head and neck cancer survivors: dynamics of independent but interconnected factors

  Sylvie E. Delanian

  Frontiers in Oncology

  doi 10.3389/fonc.2026.1941783

• Original Research

  Published 9 October 2026

  Research trends and emerging topics in gut microbiota-derived metabolites and diabetic kidney disease: a multi-database bibliometric analysis (2014–2025)

  Xinyu Yang · Xiangning Huang · Yaru Shi · Yunfeng Yu · Rong Yu

  Frontiers in Microbiology

  doi 10.3389/fmicb.2026.1967850

• Hypothesis and Theory

  Published 9 October 2026

  Based on the skeletal-muscle dual stem cell chemotaxis and bidirectional differentiation mechanism to reinterpret the “sinew-bone interdependence” theory

  Jiahao Dong · Tao Chen

  Frontiers in Cell and Developmental Biology

  doi 10.3389/fcell.2026.1869812

• Review

  Published 9 October 2026

  Metabolic reprogramming and metabolic homeostasis in podocyte injury: novel mechanistic insights and natural product therapies

  Zhongjie Qu · Wenqing Ba · Meijing Tang · Wenze Jiang · Mengting Zhu · Keda Lu

  Frontiers in Cell and Developmental Biology

  doi 10.3389/fcell.2026.1978760

• Original Research

  Published 9 October 2026

  A novel CAF-related gene signature for prognostic and immunotherapy response prediction in PDAC based on single-cell RNA-seq and bulk RNA-seq data

  Xuezhi Du · Zesheng Li · Yuwei Wang · Lei Han · Jinjin Sun · Weipeng Gong

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1873756