Articles

Showing 300 articles

• Review

  Published 12 October 2026

  Copper complexes in the triple-negative breast cancer landscape: advances and opportunities

  Paula Marynella Alves Pereira Lima · André Carlos Pereira de Matos · Gabriela da Silva Guimarães · Laryssa Aparecida Sales Barbosa · Thaise Gonçalves Araújo

  Frontiers in Molecular Biosciences

  doi 10.3389/fmolb.2026.1931263

• Original Research

  Published 12 October 2026

  Socioeconomic costs and health-related quality of life associated with oculopharyngeal muscular dystrophy

  Ian C. Smith · Alyssa Grant · Lola E. R. Lessard · Homira Osman · Fien Oelbrandt · Hanns Lochmüller · Hugh J. McMillan · Gerald Pfeffer · Lawrence Korngut · Cynthia Gagnon · Stacey Lintern · Katherine A. Selby · Ari Breiner · Kednapa Thavorn · Jodi Warman-Chardon

  Frontiers in Public Health

  doi 10.3389/fpubh.2026.1918801

• Review

  Published 12 October 2026

  From environmental occurrence to human exposure: multisystem toxicity, immune-relevant mechanisms, and gaps in health-risk assessment of liquid crystal monomers

  Hongchi Zhang · Jingle Qiu · Zhenyu Lu · Xiangbin Zheng · Xia Huo · Xijin Xu

  Frontiers in Public Health

  doi 10.3389/fpubh.2026.1977975

• Systematic Review

  Published 12 October 2026

  The CXCL12/CXCR4 axis in breast cancer-associated fibroblasts: a transcriptome analysis and systematic literature review

  Sergey Vladimirov · David Sergeevichev · Maria Bogachek · Alina Kazakova · Anastasia Leonteva · Vladimir Richter · Anna Nushtaeva

  Frontiers in Bioengineering and Biotechnology

  doi 10.3389/fbioe.2026.1920541

• Original Research

  Published 12 October 2026

  Integrative population genetics and multi-omics reveal IL15RA as a shared pathogenic hub in rheumatoid arthritis-related heart failure

  Qishun Geng · Chaoying Wen · Meijia Yang · Yuhan Zhou · Meng Yang · Qishun Geng · Jie Zhao

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1956897

• Review

  Published 12 October 2026

  Recombinant bacterial β -galactosidases for lactose bioconversion and galacto-oligosaccharide production: a comparative overview

  Anel Kostanova · Yuliya Shamsiyeva · Zhiger Akishev · Bekbolat Khassenov · Annelya Tursunbekova

  Frontiers in Microbiology

  doi 10.3389/fmicb.2026.1943869

• Original Research

  Published 12 October 2026

  Machine learning–based validation of Human Phenotype Ontology (HPO) terms for systemic autoinflammatory diseases using the Eurofever Registry: the ODINO project

  Caterina Matucci-Cerinic · Giacomo Cavalca · Matteo Vergani · Roberta Caorsi · Marielle van Gjin · Guilaine Boursier · Eugenia Mosci · Giovanni Fiorito · Paolo Uva · Marco Gattorno

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1936099

• Review

  Published 12 October 2026

  Epigenetic and mitochondrial regulation in kidney disease: emerging mechanisms and therapeutic opportunities

  Atul Rawat · Narayan Prasad · Chandan Komalkumar · Harshit Singh · Saurabh Chaturvedi · Sultan Ahmed · Brijendra Kumar · Ravi Shankar Kushwaha

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1910925

• Review

  Published 12 October 2026

  Microbial-derived metabolites in cancer: evidence boundaries, immune mechanisms and translational pathways

  Xuefeng Shi · Shunjun Wang · Wenhao Ouyang

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1947330

• Brief Research Report

  Published 12 October 2026

  Distinct spatial immune architectures in tumor and tumor-adjacent tissues of early-stage non-small cell lung cancer

  Isabella Polic · Claudio Arrechedera · Jared K. Slone · Amanda Montoya · Emily Bontekoe · Peixin Jiang · Anika Patel · Tatiana V. Karpinets · Xiaogang Wu · Xingzhi Song · Qianyun Luo · Heladio Ibarguen · Auriole Tamegnon · Mei Jiang · Cara Haymaker · Annikka Weissferdt · Ara A. Vaporciyan · Lydia E. Kavraki · Tina Cascone · Ignacio Wistuba · Luisa Maren Solis Soto · John V. Heymach · Jianjun Zhang · Don L. Gibbons · Alexandre Reuben

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1981839

• Systematic Review

  Published 12 October 2026

  Global trends and hotspots of genetic research on non-syndromic cleft lip with or without cleft palate: a bibliometric and bioinformatics analysis

  Yuxuan Shang · Mingjian Zhao · Shuangshuang Gao · Shikang Gao · Mengru Zhu

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1907333

• Methods

  Published 12 October 2026

  A modular verification and validation framework for hybrid-capture next-generation sequencing HLA typing in clinical histocompatibility laboratories

  Alice Scarpa · Diego Ferrarese · Samantha Guidotti · Veronica Scaglia · Angela Rossi

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1959391

• Original Research

  Published 12 October 2026

  Multi-model genome-wide association analysis reveals natural allelic variation and candidate loci for kernel phytic acid content in quality protein maize

  Sushil Kumar · Sourabh Kumar · Dinesh Kumar Saini · Rainy Rainy · Abhijit Kumar Das · Chikkappa G. Karjagi · Dharampaul Chaudhary · Shailendra Singh Gaurav · Ramesh Kumar

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1925511

• Original Research

  Published 12 October 2026

  Cross-lineage anomaly detection of microRNA expression: a framework for deriving exploratory candidate biomarkers in sarcoma

  Mritunjoy Dey · Piotr Remiszewski · Ewelina Perdas · Paweł Golik · Jakub Piątkowski · Anna M. Czarnecka

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1907450

• Review

  Published 12 October 2026

  Early life stress, lower urinary tract dysfunction, and respiratory disease: a proposed shared-mechanism framework

  Tadanobu Chuyo Kamijo · Mayoko Tsuji

  Frontiers in Physiology

  doi 10.3389/fphys.2026.1929695

• Original Research

  Published 12 October 2026

  Whole-exome sequencing reveals cumulative rare variant burden associated with susceptibility to anti-tuberculosis drug-induced liver injury in a Han Chinese cohort

  Yang Hao · Xiaoqing Zhang · Daiyun Huang · Shengyin Qin · Yunxiao Lin · Jianwen Ruan · Lu Shen · Na Zhang · Zhenting Wang · Cong Huai · Jianquan Zhang

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1952049

• Original Research

  Published 12 October 2026

  Nonlinear relationship between serum LH levels on hCG trigger day and live birth rates in patients with fresh embryo transfer: a retrospective cohort study

  Yue Zhang · Yuxuan Xiao · Aimin Yang · Yang Yang · Lei Jiang · Jiahua Zheng · Kaixuan Guo · Wei Wang

  Frontiers in Endocrinology

  doi 10.3389/fendo.2026.1957191

• Review

  Published 12 October 2026

  Role of histone post-translational modifications in preeclampsia: from pathogenesis to diagnostic and therapeutic strategies

  Yuanxuan Ma · Renwei Zhang · Mengting Yang · Jingli Wang · Bo Hou · Shiguo Liu

  Frontiers in Endocrinology

  doi 10.3389/fendo.2026.1973542

• Original Research

  Published 9 October 2026

  Influence of yoga on the epigenetics of obesity: a study on its short- and medium-term benefits in the treatment of patients with severe/morbid obesity eligible for bariatric surgery

  Carmela Asteria · Giorgia Scichilone · Rosanna Cardani · Dejan Lazarevic · Valentina Milani · Federico Ambrogi · Laura Valentina Renna · Marco Morelli · Francesca Giannese · Anna Sofia Tascini · Nicoletta Caridi · Fabiana Barbieri · Michela Ravelli · Alessandro Giovanelli

  Frontiers in Public Health

  doi 10.3389/fpubh.2026.1858629

• Review

  Published 9 October 2026

  Evidence boundaries and integrated disease management of microbial disease risks in protected Cymbidium faberi production: a translational framework and validation agenda

  Yufeng Deng · Dongfeng Wei · Shichao Gu · Min Yu · Jinzhi Yao · Meicheng Zhao · Lei Qin · Taiji Kou

  Frontiers in Plant Science

  doi 10.3389/fpls.2026.1952084

• Original Research

  Published 9 October 2026

  Whole-genome sequencing analysis of phylogenetic relationships and lineage diversity of Mycobacterium tuberculosis in Western Kenya

  Susan Musau · Eleanor I. Lamont · Victor Moses Musyoki · Susan Odera · Noel Onyango · Steve Wandiga · Inosters Wambua Nzuki · Bob Morrison · Reymond Mumo · David Sherman · Marianne W. Mureithi · Videlis Nduba

  Frontiers in Microbiology

  doi 10.3389/fmicb.2026.1980516

• Original Research

  Published 9 October 2026

  Sodium-dependent multivitamin transporter deficiency caused by novel SLC5A6 mutations: a clinical case and personalized mice model study

  Anastasia V. Priymak · Olga A. Averina · Margarita A. Novikova · Oleg A. Permyakov · Svetlana A. Garmash · Alexander Yu Rudenko · Vlasta O. Bobrynina · Alexander M. Mazur · Artem V. Artiukhov · Vasily A. Aleshin · Olga A. Bazhanova · Polina A. Zotova · Mikhail O. Bortyazh · Mariia A. Emelianova · Olga O. Grigorieva · Ekaterina A. Nikolaeva · Vasily N. Manskikh · Olga A. Dontsova · Ekaterina Yu Zakharova · Egor B. Prokhortchouk · Petr V. Sergiev

  Frontiers in Cell and Developmental Biology

  doi 10.3389/fcell.2026.1925753

• Original Research

  Published 9 October 2026

  Performance of non-invasive prenatal screening for 15q11q13 copy number variations in a cohort of 90,693 pregnancies

  Diyu Chen · Liang Hu · Hongyan Niu · Zhenming Li · Shuxian Zeng · Xiaoyi Cong · Pingnan Sun · Weiqiang Liu

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1937108

• Brief Research Report

  Published 9 October 2026

  A spectrum of tumorigenesis in an IDH1 -mosaic patient with Ollier disease, acute myeloid leukaemia, and parathyroid adenoma

  Victoria Lopez Delhoulle · Adrien De Voeght · Rafael Fernandez Carazo · Iulia Nechifor-Potorac · Edith Sepulchre · Evelyne Willems · Patrick Pétrossians · Benjamin Koopmansch · Elisa Docampo · Vincent Bours · Saskia Bulk · Frédéric Lambert

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1889201

• Mini Review

  Published 9 October 2026

  Distinct host genetic determinants of HIV acquisition and disease progression: the case of classical HLA class I

  Marion Amujal · James Bumba

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1982540

• Policy Brief

  Published 8 October 2026

  Genomic surveillance of mosquito resistance to guide cost-effective insecticide policy in Rwanda

  Nzungize Lambert · Naomi A. Dyer · Umuhoza Diane · Ellie Sherrard-Smith · Mutesa Leon

  Frontiers in Tropical Diseases

  doi 10.3389/fitd.2026.1887818

• Original Research

  Published 8 October 2026

  A personalized nutrition intervention advances meal timing and is associated with reduced postprandial lipid and inflammatory responses in night shift workers

  Maaike van der Rhee · Tim J. van den Broek · Inês Chaves · Martijn E. T. Dollé · Linda W. M. van Kerkhof · Alex Burdorf · Heidi M. Lammers-Van der Holst · Johanneke E. Oosterman · Suzan Wopereis

  Frontiers in Nutrition

  doi 10.3389/fnut.2026.1912094

• Original Research

  Published 8 October 2026

  A light-responsive engineered probiotic system to alleviate anxiety via gut-brain axis

  Yuling Chang · Zhaofang Hang · Yuhan Zhang · Yuhao Zhu · Xingang Li · Xuejun Wang · Di Zhang

  Frontiers in Bioengineering and Biotechnology

  doi 10.3389/fbioe.2026.1864003

• Original Research

  Published 8 October 2026

  High-resolution characterization of classical and non-classical HLA diversity reveals important admixture in Brazilian indigenous

  Newton De Freitas Centurião · Lidia Cardoso Francisco · Manuel Mindlin Lafer · Roberta Sitnik · João Renato Rebello Pinho · Giselle Lima Groetares · Elena Outon Alonso · Gabriella Camerini Maciel · Margareth Afonso Torres

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1948784

• Correction

  Published 8 October 2026

  Correction: Tissue-specific aging—a new paradigm based on transcriptional insights from select model systems and humans

  Stewart Frankel · Blanka Rogina

  Frontiers in Genetics

  doi 10.3389/fgene.2026.2008131

• Case Report

  Published 8 October 2026

  Case Report: Case series: growth hormone replacement for severe growth hormone deficiency during BRAF inhibitor therapy in pediatric low-grade glioma: long-term follow-up

  Marta Panciroli · Antonio Verrico · Marco Crocco · Sara Cencioni · Chiara Morreale · Antonia Ramaglia · Valentina Iurilli · Gianluca Piccolo · Claudia Milanaccio · Mohamad Maghnie · Natascia Di Iorgi

  Frontiers in Endocrinology

  doi 10.3389/fendo.2026.1940850

• Original Research

  Published 8 October 2026

  Composite indices of insulin resistance and sensitivity versus matched component-variable models for incident diabetes prediction

  Qiujun Liu · Canyu Liu · Yuanhao Lv · Yanxuan Liu

  Frontiers in Endocrinology

  doi 10.3389/fendo.2026.1957473

• Case Report

  Published 8 October 2026

  Case Report: Hyperinsulinemic hypoglycemia and arterial aneurysms in KAT6B-related disorder: case observation and literature perspective

  Nicola Improda · Francesco Maria Rosanio · Giada Ballarin · Fabio Acquaviva · Giangiacomo di Nardo · Lorenza Lepore · Antonia Pascarella · Virginia Mirra · Maria Rosaria Licenziati

  Frontiers in Endocrinology

  doi 10.3389/fendo.2026.1938759

• Original Research

  Published 8 October 2026

  Apparent dissociation between hemodynamic and neurochemical responses during chemogenetic modulation of cortical circuits in rats

  Fatemeh Anvari-Vind · Nathalie Just

  Frontiers in Neuroscience

  doi 10.3389/fnins.2026.1916498

• Brief Research Report

  Published 7 October 2026

  Molecular identification of Comstockaspis perniciosa and its associated Aphytis parasitoid in apple orchards of Kazakhstan

  Alibek Makhambetov · Valeriya Kostyukova · Gulnur Zholdasbek · Zarina Dairbekova · Bakyt Dulat · Alexandr Pozharskiy · Gulshariya Kairova · Dilyara Gritsenko

  Frontiers in Insect Science

  doi 10.3389/finsc.2026.1960516

• Original Research

  Published 7 October 2026

  Molecular epidemiology and geographic distribution of Theileria spp. in Kazakhstan: a countrywide cattle survey and a southern sheep survey

  Kassym Mukanov · Alexander Ostrovskii · Dinara Kamalova · Anara Ryskeldina · Amirkhan Kassen · Maxat Berdikulov · Sarsenbay Abdrakhmanov · Alexandr Shevtsov · Christian Bauer

  Frontiers in Veterinary Science

  doi 10.3389/fvets.2026.1987322

• Original Research

  Published 7 October 2026

  Bioremediation of lead and manganese from wastewater using different Bacillus spp. with FTIR spectroscopic analysis

  Walaa M. Nasr · Mohamed A. El-Kammah · Mohamed A. S. Abdelrazek · Hassan E. Flefel · Hossam Khedr · Nada A. El-Morsy · Mohamed E. Elmasry

  Frontiers in Environmental Science

  doi 10.3389/fenvs.2026.1936478

• Original Research

  Published 7 October 2026

  Duplication of the SOX3 gene in an SRY -negative boy with a 46,XX karyotype: a case report and a review of the literature

  Júlia Martinková · Hana Řezáčová · Alena Šantavá · Jana Drábová · Miroslav Štolfa · Radek Vodička · Jiřina Zapletalová · Miroslava Balaščaková · Anna Křepelová

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1861766

• Hypothesis and Theory

  Published 7 October 2026

  The developmental dopamine trajectory hypothesis of ADHD across the lifespan

  Raly James Perez Custodio · Stephan Getzmann · Edmund Wascher · Michael C. Pan · Florence Ingred Samante · Fred Lawrence Samante · Bung-Nyun Kim · Hee Jin Kim · Eugene C. Yi · Jae Hoon Cheong

  Frontiers in Psychiatry

  doi 10.3389/fpsyt.2026.1944446

• Perspective

  Published 6 October 2026

  Validating electrical stimulation through the somatosensory system: a perspective on mismatch negativity and auditory prostheses

  Sergei Tugin · Polina Pavlova · Natalia Karpova · Boriss Sagalajev

  Frontiers in Human Neuroscience

  doi 10.3389/fnhum.2026.1912789

• Original Research

  Published 6 October 2026

  Daily regulation of glucocerebrosidase activity and impact of fixed-time rotarod training in a mouse model of Gba1 -associated Parkinson's disease

  Chiara Bertasini · Shima Tavakolian Haghighi · Maria Giusy Bruno · Fabio Paio · Carlo Alberto Artusi · Matteo Brunelli · Federico Schena · Massimo Venturelli · Ugo Moretti · Maria Grazia Romanelli · Giovanna Paolone

  Frontiers in Cellular Neuroscience

  doi 10.3389/fncel.2026.1924016

• Original Research

  Published 6 October 2026

  Clinical factors predicting tic persistence into adulthood

  Ariadne Kaylor · Joshua A. Senior · Evan Realbuto · Jenna LaRochelle · Dongmei Yu · Daisy T. Noriega-Makarskyy · Angela Essa · Carol A. Mathews · Jeremiah M. Scharf

  Frontiers in Psychiatry

  doi 10.3389/fpsyt.2026.1948693

• Original Research

  Published 6 October 2026

  Adverse childhood experiences and functional stability in the affective-to-psychotic spectrum: a longitudinal multistate analysis of employment and relationship outcomes

  Fanny Senner · Elena Merkle · Michael Lauseker · Eva C. Schulte · Urs Heilbronner · Monika Budde · Daniela Reich-Erkelenz · Mojtaba Oraki Kohshour · Alba Navarro-Flores · Maria Heilbronner · Ion-George Anghelescu · Volker Arolt · Bernhard T. Baune · Detlef E. Dietrich · Andreas J. Fallgatter · Christian Figge · Markus Jäger · Georg Juckel · Carsten Konrad · Nathalie Kühnen · Eva Z. Reininghaus · Max Schmauß · Andrea Schmitt · Simon Senner · Carsten Spitzer · Alkomiet Hasan · Peter Falkai · Thomas G. Schulze · Kristina Adorjan · Sergi Papiol · Sophie-Kathrin Greiner

  Frontiers in Psychiatry

  doi 10.3389/fpsyt.2026.1930635

• Review

  Published 6 October 2026

  Context-dependent oxytocin receptor signaling: from molecular architecture to transcript-level receptor engineering

  Benjamin Jurek · Julia J. Winter · Daniel S. Quintana

  Frontiers in Neuroscience

  doi 10.3389/fnins.2026.1938379

• Review

  Published 5 October 2026

  Epigenetics in Alzheimer’s disease: from molecular mechanisms to emerging novel biomarkers

  Elisabetta D’Aversa · Miriana Grisafi · Salvatore Pernagallo · Francesca Salvatori · Ajay V. Singh · Alessia Nucciarone · Veronica Tisato · Donato Gemmati

  Frontiers in Aging Neuroscience

  doi 10.3389/fnagi.2026.1959361

• Original Research

  Published 5 October 2026

  Instillation timing as the main determinant of aqueous humor nepafenac exposure

  Angelo Macri · Annalisa Salis · Margherita Tarallo · Michele Iester · Gianluca Damonte · Francesca Mattioli

  Frontiers in Molecular Biosciences

  doi 10.3389/fmolb.2026.1913752

• Original Research

  Published 5 October 2026

  Engineering a hemoglobin variant with enhanced stability and oxygen affinity using a protein language model

  Sergey Shityakov · Alexander S. Novikov · Ekaterina V. Skorb · Thomas Dandekar

  Frontiers in Chemistry

  doi 10.3389/fchem.2026.1898272

• Original Research

  Published 5 October 2026

  Quantitative analysis of posture and gait in the differential diagnosis of functional and organic motor disorders: a multicenter cross-sectional study

  Michela Russo · Roberto Erro · Carlo Ricciardi · Marialuisa Gandolfi · Angela Sandri · Marianna Amboni · Elisabetta Sarasso · Andrea Gardoni · Silvia Basaia · Sofia Cuoco · Immacolata Carotenuto · Claudia Vinciguerra · Annibale Botto · Daniele Giuseppe Romano · Ilaria Antonella Di vico · Mirta Fiorio · Serena Camozzi · Giulia Pedrotti · Anna Fratucello · Giancarlo Mansueto · Francesca Benedetta Pizzini · Marco Barillari · Matteo Francesco Lauriola · Mariachiara Tozzi · Francesca Rusciano · Christian Geroin · Melania Fasoli · Angela Marotta · Francesca Salaorni · Giovanna Maddalena Squintani · Sara Mariotto · Stefano Tamburin · Fabio Paio · Giuseppe De Biasi · Giuseppe Piscosquito · Elisa Sibilla · Elisa Canu · Massimo Filippi · Federica Agosta · Maria Romano · Paolo Barone · Francesco Amato · Michele Tinazzi · Maria Teresa Pellecchia

  Frontiers in Bioengineering and Biotechnology

  doi 10.3389/fbioe.2026.1872332