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Frontiers in Systems Biology

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An exciting journal integrating theory, experimentation, and practical application across biology and biomedicine to tackle some of the most urgent questions we face as humans.

Frontiers in Systems Biology is an interdisciplinary, PubMed Central, DOAJ, Scopus and WoS ESCIindexed journal that breaks down the individualistic silos of modernday research and promotes integration and systems thin...

About the journal

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  • Peer review

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  • Publishing fees

    Article processing charges apply to articles accepted for publication by our external editors after rigorous peer review.

Editors

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Edoardo Saccenti

Wageningen University and Research

Netherlands

Specialty Chief Editor

Data and Model Integration

Eric H Chang

Feinstein Institute for Medical Research

United States

Specialty Chief Editor

Integrative Systems Neuroscience

Harinder Singh

University of Pittsburgh

United States

Specialty Chief Editor

Systems and Synthetic Immunology

Ioannis P Androulakis

Rutgers, The State University of New Jersey

United States

Specialty Chief Editor

Translational Systems Biology and In Silico Trials

Jennifer Lovejoy

HudsonAlpha Institute for Biotechnology

United States

Specialty Chief Editor

Systems Concepts, Theory and Policy in Biology and Medicine

Jishnu Das

University of Pittsburgh

United States

Specialty Chief Editor

Systems and Synthetic Immunology

Rongling Wu

The Pennsylvania State University (PSU)

United States

Specialty Chief Editor

Integrative Genetics and Genomics

300 editors · 0 reviewers

Articles

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Research topics

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About the journal

Scope

Frontiers in Systems Biology is an interdisciplinary, PubMed Central, DOAJ, Scopus and WoS ESCI-indexed journal that breaks down the individualistic silos of modern-day research and promotes integration and systems thinking across scientific fields to achieve answers to life’s biggest questions. With an international editorial board led by Field Chief Editor Prof Yoram Vodovotz (University of Pittsburgh, USA), Frontiers in Systems Biology explores the complexities of biology at a systems level and welcomes submissions that integrate theory, experimentation, and practical application, and that which helps to address fundamental questions that bridge the gap between different disciplines and methods. The journal covers the following subject areas: data and model integration integrative genetics and genomics integrative systems microbiology integrative systems neuroscience integrative systems ecology, evolution, and plant science multiscale mechanistic modeling systems concepts, theory and policy in biology and medicine systems and synthetic immunology translational systems biology and In Silico trials. Manuscripts that use a reductionist approach for genetic and genomic research, studies that focus solely on pre-clinical models or descriptive network models without dynamic representation of biological mechanisms, and machine learning/AI models that focus solely on diagnosis without potential interventions are not suitable for publication in this journal. Please note this journal does not accept mendelian randomization or bibliometric studies. Frontiers in Systems Biology is committed to advancing developments in the field of systems biology research by communicating scientific knowledge to researchers and the public alike, to enable the scientific breakthroughs of the future. As part of our commitment to promoting Systems Thinking, we have undertaken a number of webinar events within the journal which can be viewed on the Frontiers in Systems Biology Playlist on YouTube.

Aims

Frontiers in Systems Biology is an interdisciplinary, PubMed Central, DOAJ, Scopus and WoS ESCI-indexed journal that breaks down the individualistic silos of modern-day research and promotes integration and systems thinking across scientific fields to achieve answers to life’s biggest questions.

With an international editorial board led by Field Chief Editor Prof Yoram Vodovotz (University of Pittsburgh, USA), Frontiers in Systems Biology explores the complexities of biology at a systems level and welcomes submissions that integrate theory, experimentation, and practical application, and that which helps to address fundamental questions that bridge the gap between different disciplines and methods.

The journal covers the following subject areas:

data and model integration

integrative genetics and genomics

integrative systems microbiology

integrative systems neuroscience

integrative systems ecology, evolution, and plant science

multiscale mechanistic modeling

systems concepts, theory and policy in biology and medicine

systems and synthetic immunology

translational systems biology and In Silico trials.

Manuscripts that use a reductionist approach for genetic and genomic research, studies that focus solely on pre-clinical models or descriptive network models without dynamic representation of biological mechanisms, and machine learning/AI models that focus solely on diagnosis without potential interventions are not suitable for publication in this journal. Please note this journal does not accept mendelian randomization or bibliometric studies.

Frontiers in Systems Biology is committed to advancing developments in the field of systems biology research by communicating scientific knowledge to researchers and the public alike, to enable the scientific breakthroughs of the future.

As part of our commitment to promoting Systems Thinking, we have undertaken a number of webinar events within the journal which can be viewed on the Frontiers in Systems Biology Playlist on YouTube.

Source: https://www.frontiersin.org/journals/systems-biology/about

ISSN
2674-0702
Editor-in-Chief
Yoram Vodovotz (University of Pittsburgh, Pittsburgh, United States) — Field Chief Editor
Established
2026

Sections

  • Data and Model Integration

    Official section page: https://www.frontiersin.org/journals/systems-biology/sections/data-and-model-integration

  • Integrative Genetics and Genomics

    Official section page: https://www.frontiersin.org/journals/systems-biology/sections/integrative-genetics-and-genomics

  • Integrative Systems Ecology, Evolution and Plant Science

    Official section page: https://www.frontiersin.org/journals/systems-biology/sections/integrative-systems-ecology-evolution-and-plant-science

  • Integrative Systems Microbiology

    Official section page: https://www.frontiersin.org/journals/systems-biology/sections/integrative-systems-microbiology

  • Integrative Systems Neuroscience

    Official section page: https://www.frontiersin.org/journals/systems-biology/sections/integrative-systems-neuroscience

  • Multiscale Mechanistic Modeling

    Official section page: https://www.frontiersin.org/journals/systems-biology/sections/multiscale-mechanistic-modeling

  • Systems Concepts, Theory and Policy in Biology and Medicine

    Official section page: https://www.frontiersin.org/journals/systems-biology/sections/systems-concepts-theory-and-policy-in-biology-and-medicine

  • Systems and Synthetic Immunology

    Official section page: https://www.frontiersin.org/journals/systems-biology/sections/systems-and-synthetic-immunology

  • Translational Systems Biology and In Silico Trials

    Official section page: https://www.frontiersin.org/journals/systems-biology/sections/translational-systems-biology-and-in-silico-trials

Article types accepted

  • Original Research
  • Systematic Review
  • Methods
  • Review
  • Mini Review
  • Policy and Practice Reviews
  • Hypothesis and Theory
  • Perspective
  • Clinical Trial
  • Case Report
  • Community Case Study
  • Data Report
  • Policy Brief
  • Brief Research Report
  • General Commentary
  • Opinion
  • Correction
  • Editorial
  • Specialty Grand Challenge
  • Technology and Code
  • FAIR² Data

Fees and currencies

  • Article processing charges (official)
  • - Category A: CHF 2,195 — Original Research, Systematic Review, Methods, Review, Policy and Practice Reviews, Hypothesis and Theory, Clinical Trial, Technology and Code
  • - Category B: CHF 1,750 — Mini Review, Perspective, Case Report, Community Case Study, Data Report, Policy Brief, Brief Research Report, General Commentary, Opinion
  • - Category C: CHF 0 — Correction, Editorial
  • Currency: CHF

Fees are charged only after acceptance. Waivers and discounts are available for authors with limited funding.

Fees and waivers policy

Editorial policies

Peer review

  • Official peer-review process: https://www.frontiersin.org/about/peer-review

Publication ethics

  • Policies and publication ethics: https://www.frontiersin.org/guidelines/policies-and-publication-ethics

Indexing

  • Bielefeld Academic Search Engine (BASE)
  • Biological Abstracts
  • BIOSIS Previews
  • CNKI Scholar
  • CLOCKSS
  • Crossref
  • Dimensions
  • Chinese Academy of Sciences GoOA
  • OpenAIRE
  • EBSCO
  • DOAJ
  • Scopus
  • Web of Science Emerging Sources Citation Index (ESCI)
  • Committee on Publication Ethics (COPE)
  • PubMed Central (PMC)
  • ProQuest

Affiliated societies

  • Committee on Publication Ethics

Source: https://www.frontiersin.org/journals/systems-biology/about

Instructions for authors

Accepted article types

  • Original Research (fee category A)
  • Systematic Review (fee category A)
  • Methods (fee category A)
  • Review (fee category A)
  • Mini Review (fee category B)
  • Policy and Practice Reviews (fee category A)
  • Hypothesis and Theory (fee category A)
  • Perspective (fee category B)
  • Clinical Trial (fee category A)
  • Case Report (fee category B)
  • Community Case Study (fee category B)
  • Data Report (fee category B)
  • Policy Brief (fee category B)
  • Brief Research Report (fee category B)
  • General Commentary (fee category B)
  • Opinion (fee category B)
  • Correction (fee category C)
  • Editorial (fee category C)
  • Specialty Grand Challenge
  • Technology and Code (fee category A)
  • FAIR² Data

Author guidelines

  • https://www.frontiersin.org/journals/systems-biology/for-authors/author-guidelines

Peer review

  • https://www.frontiersin.org/about/peer-review

Journal metrics

Citation score
4.7
Impact indicator
0.74
Acceptance rate
15
Articles
50
Total views
0
Downloads
0
Citations
0

Internal metrics, calculated on this platform and maintained by the editorial office.

Official bibliometric indicators

Impact factor
2.6
CiteScore
4.7
Citations
1226
Acceptance rate
33
Time to publication
105

Source: official publisher page · retrieved 2026-10-16

Some values were updated by the editorial office on 2026-10-22.